Macaca mulatta (rhesus monkey): 693523 Help Entry 693523            CDS       T01028                                  Symbol ADCY3 Name (RefSeq) adenylate cyclase type 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism mcc  Macaca mulatta (rhesus monkey) Pathway mcc00230   Purine metabolism mcc01100   Metabolic pathways mcc01522   Endocrine resistance mcc04015   Rap1 signaling pathway mcc04020   Calcium signaling pathway mcc04022   cGMP-PKG signaling pathway mcc04024   cAMP signaling pathway mcc04062   Chemokine signaling pathway mcc04072   Phospholipase D signaling pathway mcc04081   Hormone signaling mcc04082   Neuroactive ligand signaling mcc04114   Oocyte meiosis mcc04211   Longevity regulating pathway mcc04213   Longevity regulating pathway - multiple species mcc04261   Adrenergic signaling in cardiomyocytes mcc04270   Vascular smooth muscle contraction mcc04371   Apelin signaling pathway mcc04540   Gap junction mcc04611   Platelet activation mcc04713   Circadian entrainment mcc04714   Thermogenesis mcc04723   Retrograde endocannabinoid signaling mcc04724   Glutamatergic synapse mcc04725   Cholinergic synapse mcc04727   GABAergic synapse mcc04740   Olfactory transduction mcc04750   Inflammatory mediator regulation of TRP channels mcc04911   Insulin secretion mcc04912   GnRH signaling pathway mcc04913   Ovarian steroidogenesis mcc04914   Progesterone-mediated oocyte maturation mcc04915   Estrogen signaling pathway mcc04916   Melanogenesis mcc04918   Thyroid hormone synthesis mcc04921   Oxytocin signaling pathway mcc04923   Regulation of lipolysis in adipocytes mcc04925   Aldosterone synthesis and secretion mcc04926   Relaxin signaling pathway mcc04927   Cortisol synthesis and secretion mcc04928   Parathyroid hormone synthesis, secretion and action mcc04934   Cushing syndrome mcc04935   Growth hormone synthesis, secretion and action mcc04962   Vasopressin-regulated water reabsorption mcc04970   Salivary secretion mcc04971   Gastric acid secretion mcc04972   Pancreatic secretion mcc04976   Bile secretion mcc05032   Morphine addiction mcc05163   Human cytomegalovirus infection mcc05166   Human T-cell leukemia virus 1 infection mcc05200   Pathways in cancer mcc05207   Chemical carcinogenesis - receptor activation mcc05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mcc00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     693523 (ADCY3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     693523 (ADCY3)    04371 Apelin signaling pathway     693523 (ADCY3)    04020 Calcium signaling pathway     693523 (ADCY3)    04072 Phospholipase D signaling pathway     693523 (ADCY3)    04024 cAMP signaling pathway     693523 (ADCY3)    04022 cGMP-PKG signaling pathway     693523 (ADCY3)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     693523 (ADCY3)    04081 Hormone signaling     693523 (ADCY3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     693523 (ADCY3)   09144 Cellular community - eukaryotes    04540 Gap junction     693523 (ADCY3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     693523 (ADCY3)    04062 Chemokine signaling pathway     693523 (ADCY3)   09152 Endocrine system    04911 Insulin secretion     693523 (ADCY3)    04923 Regulation of lipolysis in adipocytes     693523 (ADCY3)    04912 GnRH signaling pathway     693523 (ADCY3)    04913 Ovarian steroidogenesis     693523 (ADCY3)    04915 Estrogen signaling pathway     693523 (ADCY3)    04914 Progesterone-mediated oocyte maturation     693523 (ADCY3)    04921 Oxytocin signaling pathway     693523 (ADCY3)    04926 Relaxin signaling pathway     693523 (ADCY3)    04935 Growth hormone synthesis, secretion and action     693523 (ADCY3)    04918 Thyroid hormone synthesis     693523 (ADCY3)    04928 Parathyroid hormone synthesis, secretion and action     693523 (ADCY3)    04916 Melanogenesis     693523 (ADCY3)    04925 Aldosterone synthesis and secretion     693523 (ADCY3)    04927 Cortisol synthesis and secretion     693523 (ADCY3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     693523 (ADCY3)    04270 Vascular smooth muscle contraction     693523 (ADCY3)   09154 Digestive system    04970 Salivary secretion     693523 (ADCY3)    04971 Gastric acid secretion     693523 (ADCY3)    04972 Pancreatic secretion     693523 (ADCY3)    04976 Bile secretion     693523 (ADCY3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     693523 (ADCY3)   09156 Nervous system    04724 Glutamatergic synapse     693523 (ADCY3)    04727 GABAergic synapse     693523 (ADCY3)    04725 Cholinergic synapse     693523 (ADCY3)    04723 Retrograde endocannabinoid signaling     693523 (ADCY3)   09157 Sensory system    04740 Olfactory transduction     693523 (ADCY3)    04750 Inflammatory mediator regulation of TRP channels     693523 (ADCY3)   09149 Aging    04211 Longevity regulating pathway     693523 (ADCY3)    04213 Longevity regulating pathway - multiple species     693523 (ADCY3)   09159 Environmental adaptation    04713 Circadian entrainment     693523 (ADCY3)    04714 Thermogenesis     693523 (ADCY3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     693523 (ADCY3)    05207 Chemical carcinogenesis - receptor activation     693523 (ADCY3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     693523 (ADCY3)    05163 Human cytomegalovirus infection     693523 (ADCY3)   09165 Substance dependence    05032 Morphine addiction     693523 (ADCY3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     693523 (ADCY3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     693523 (ADCY3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     693523 (ADCY3) Enzymes [BR:mcc01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      693523 (ADCY3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N HNOBA RAP1 Peptidase_S49_N Motif Other DBs NCBI-GeneID:  693523 NCBI-ProteinID:  NP_001192150 Ensembl:  ENSMMUG00000009600 LinkDB All DBs Position 13:84069839..84171041 Genome browser AA seq 1144 aa AA seqDB search MPRNQGFSEPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMRLTFVPE SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSSDKLAPLAVAGIGLLLDII LFVLCKKELLPDRATRRVVPYLLWLLITAQIFSYLGLNFARAHAASDTVGWQVFFVFSFF ITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQEELKGMQLLREILANVFLYLCAIAVG IMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGDGGSRCD YLEEKGIETYLIIASKPEVKKTATQNGLNGSALPNGAPASSKSSSPALIETKEPNGSAHS SGSTSEKPEEQDAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESA QVVKKRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCTALVEILIDPWLMTN YVTFVVGEILLLILTICSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMAN VVDMLSCLQYYTGPSNATAGMETKGGCLENPKYYNYVAVLSLIATIMLVQVSHMVKLTLM LLVAGAVAAINLYAWRPVFDEYDHRRFREHDLPMVTLEKMQGFTPGLNGTDRLPLVPSKY SMTVMVFLMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEHV ARHFLGSKKRDEELYSQTYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDFD SLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFASSNKEDKSERERWQHLADLADFA LAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVM GNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKPATFPNGPSVTLPHQV VDNS NT seq 3435 nt NT seq  +upstreamnt  +downstreamnt atgccgaggaaccagggcttctctgagcccgagtactcggccgagtactcagccgagtac tccgtcagcctgccctccgaccctgaccgcggggtgggccggacccatgaaatctcggtc cggaactcgggctcctgcctgtgcctgcctcgcttcatgcggctgaccttcgtgccggag tccttggagaacctctaccagacttacttcaaaaggcagcgccacgagaccctgctggtg ctggtggtctttgctgccctctttgactgctacgtggtggtcatgtgtgctgtggtcttc tccagcgacaagctggctcccctcgccgtggctggaattggactgctgttggacatcatc ctcttcgtgctctgcaaaaaggagctgctcccggaccgggccacccgcagagtggtgccc tatctgctgtggctgctcataactgcccagatcttctcctacctgggcctgaacttcgcg cgtgcccacgcggccagtgacaccgtgggctggcaggtcttcttcgtcttctccttcttc atcacgctgcctctcagcctcagccccatcgtgatcatctccgtggtctcctgtgtggtg cacaccttggtcctgggggtcactgtggcccagcagcagcaggaggagctgaaggggatg cagctgctgcgcgagatcctggccaacgtcttcctctacctgtgtgccatcgctgtgggc atcatgtcctactacatggctgaccgcaagcaccgcaaggccttcctggaggcccgccag tcgctggaggtgaagatgaacctggaagagcagagccagcagcaggagaacctcatgctt tccatcctgcccaagcacgtggctgatgagatgctgaaagacatgaagaaagacgagagc cagaaggaccagcagcagttcaacaccatgtacatgtaccgccatgagaacgtcagcatc ctctttgccgacatcgtgggctttacccagctgtcttctgcctgcagtgcccaggagctc gtgaagctgctcaacgagctctttgcccgctttgacaagctggcagctaaataccaccag ctgcggattaagatcctgggcgactgctactactgcatctgcggcctgcctgactaccgg gaggaccacgccgtctgctccatcctcatggggctcgccatggtggaggccatctcgtat gtgcgggagaagaccaagactggggtggacatgcgtgtgggggtgcacacgggcaccgtg ctggggggcgtcctgggccagaagcgctggcagtacgatgtgtggtcaactgacgtcact gtagccaacaagatggaggccggcggcatccctgggcgtgtgcacatctcccagagcacc atggactgcctgaaaggggagtttgatgtggaaccaggcgatgggggcagccgctgtgac tacctagaagagaagggtattgaaacctacctcatcattgcctccaagccagaggtgaag aaaacagccacccagaatggcctcaatggctcggccctgcccaatggagcaccagcttcc tcaaagtccagctcccctgccctcattgagaccaaggagcccaacgggagtgcccacagc agcgggtccacatcagagaaacccgaggagcaggatgcccaggctgacaacccctcattc cccaacccgcgccggaggctgcgcctgcaggacctggctgaccgagtggtggacgcctcc gaagacgagcacgagctcaaccagctgctcaacgaggccctgctggagcgagagtctgcc caagtagtaaagaagagaaacaccttcctcctgtccatgcggttcatggaccctgagatg gaaacacgctactcggtggagaaggagaagcagagtggggctgccttcagctgctcctgc gtcgtcctgctctgcacggctctggtcgagatactcatcgacccctggctaatgacaaac tatgtgaccttcgtggtgggtgagattctgctcctcatcctgaccatctgctccctggct gccatctttccccgggcctttcctaagaagcttgtggccttctcgacttggattgaccgg acccgctgggccaggaacacctgggccatgctcgccatcttcatcctggtgatggcaaat gtcgtggacatgctcagctgtctccagtactacacaggacccagcaacgcgacagcaggg atggagacgaagggcggctgcctggagaaccccaagtattacaactacgtggccgtgctg tctctcatcgccaccatcatgctggtgcaggtcagccacatggtgaagctcacgcttatg ctgctcgtcgcgggcgccgtggccgccatcaacctctacgcctggcgccccgtcttcgat gaatacgaccaccggcgttttcgggagcatgacttacctatggtgaccttagagaagatg cagggattcacccctgggctcaacggcactgacaggctgcccctggtgccttccaagtac tccatgacggtgatggtgttcctcatgatgctgagcttctactacttctcccgccatgta gaaaaactggcacggacacttttcttgtggaagattgaggtccacgaccagaaggaacgt gtctacgagatgcgacgctggaacgaggccttggtcaccaacatgttgcctgagcacgtg gcacgccatttcctggggtccaagaagagagatgaggagctgtacagccagacgtatgat gagattggagtcatgtttgcctccctgcccaactttgctgacttctacacagaggagagc atcaacaatggcggtatcgagtgtctgcgtttcctcaatgaaatcatctcggattttgac tctctcctggacaatcccaagttccgggtgatcaccaagatcaaaaccattggcagcacg tacatggcagcttcaggagtcacccctgacgtcaacactaatggctttgccagctccaac aaggaggacaagtctgagagagaacgctggcagcacctggctgacctggccgactttgca ctggccatgaaggatacgctcaccaacatcaacaatcagtccttcaataacttcatgctg cgcataggcatgaacaaaggcggggttctggctggggtcatcggagcccggaaaccacac tacgacatctggggcaatacggtcaatgtagccagcaggatggagtccacgggggtcatg ggcaacatccaggtggtagaagaaacccaagtcatcctccgagagtacggcttccgcttt gtgaggcgaggccccatctttgtgaagggaaagggggagttgctgaccttcttcttgaag gggcgggacaagccagccaccttccccaacggcccctctgtcacactgccccaccaggtg gtagacaactcctga

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