| Entry |
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| Symbol |
ABCC4
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| Name |
(RefSeq) multidrug resistance-associated protein 4 isoform X3
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| KO |
| K05673 | ATP-binding cassette, subfamily C (CFTR/MRP), member 4 |
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| Organism |
mcc Macaca mulatta (rhesus monkey)
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| Pathway |
| mcc04981 | Folate transport and metabolism |
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| Brite |
KEGG Orthology (KO) [BR:mcc00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
695407 (ABCC4)
09132 Signal transduction
04024 cAMP signaling pathway
695407 (ABCC4)
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
695407 (ABCC4)
04981 Folate transport and metabolism
695407 (ABCC4)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
695407 (ABCC4)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:mcc02000]
695407 (ABCC4)
Transporters [BR:mcc02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
695407 (ABCC4)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
17:complement(76790590..77082241)
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| AA seq |
1282 aa
MYSVLPEDRSQHLGEELQGFWDKEVLRAENDAQKPSLTRAIIKCYWKSYLVLGIFTLIEE
SAKVIQPIFLGKIINYFENYDPMDSVALNTAYAYATVLTVCTLILAILHHLYFYHVQCAG
MRLRIAMCHMIYRKALRLSNMAMGKTTTGQIVNLLSNDVNKFDQVTVFLHFLWAGPLQAI
AVTALLWMEIGISCLAGMAVLIILLPFQSCFGKLFSSLRSKTATFTDARIRTMNEVITGI
RIIKMYAWEKSFSDLVTNLRKKEISKILRSSYLRGMNLASFFSASKIIVFVTFTTYMLLG
NVITASRVFVAVTLYGAVRLTVTLFFPAAIEKVSEAIISIRRIQNFLLLDEISQRNRQPP
SDGKKMVHVQDFTAFWDKASETPTLQGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELA
PSHGLVSVHGRIAYVSQQPWVFSGTVRSNILFGKKYEKERYEKVIKACALKKDLQLLEDG
DLTVIGDRGTTLSGGQKARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQTLH
EKITILVTHQLQYLKAASQILILKDGKMVQKGTYTEFLKSGIDFGSLLKKDNEESEQLPV
PGTPTLRNRTFSESSVWSQQSSRPSLKDGAVETQDTENVPVTLSDENRSEGKVGFQAYKN
YFRAGAHWIVIIFLILLNTAAQVAYVLQDWWLSYWANQQSTLNVTVNGGGNVTKKLDLNW
YLGIYSGLTAATVLFGIARSLLVFYVLVNSSQTLHNKMFESILKAPVLFFDRNPIGRILN
RFSKDIGHLDDLLPLTVLDFIQTLLQVVGVVSVAVAVIPWIAIPLVPLGIVFIFLRRYFL
ETSRDVKRLESTTRSPVFSHLSSSLQGLWTIRAYKAEERCQELFDAHQDLHSEAWFLFLT
TSRWFAVRLDAICAMFVIVVAFGSLILAKTLDAGQVGLALSYALTLMGMFQWCVRQSAEV
ENMMISVERVIEYTDLEKEAPWECQKRPPPTWPHEGVIIFDNVNFMYSLDGPLVLKHLTA
LIKSREKVGIVGRTGAGKSSLISALFRLSEPEGKIWIDKILTTEIGLHDLRKKMSIIPQE
PVLFTGTMRKNLDPFNEHTDEELWNALQEVQLKETIEDLPGKMDTELAESGSNFSVGQRQ
LVCLARAILRKNQILIIDEATANVDPRTDELIQKKIREKFAHCTVLTIAHRLNTIIDSDR
IMVLDSGRLKEYDEPYVLLQNKESLFYKMVQQLGKAEAAALTETAKQVYFKRNYPHIGHT
DHMVTNTSNGQPSTLTIFETAL |
|---|
| NT seq |
3849 nt +upstreamnt +downstreamnt
atgtattcagtgctaccagaagaccgctcacagcaccttggagaggagttgcaagggttc
tgggataaagaagttttaagagctgagaatgacgcacagaagccttctttaacaagagca
atcataaagtgttactggaaatcttatttagttttgggaatttttacattaattgaggaa
agtgccaaagtaatccagcccatatttttgggaaaaattattaattattttgaaaattac
gatcccatggattccgtggctttgaacacagcgtacgcctatgccacggtgctgactgtt
tgcacgctcattttggccatactgcatcacttatatttttatcacgttcagtgtgctggg
atgaggttacgaatagccatgtgccatatgatttatcggaaggcacttcgtcttagtaac
atggccatggggaagacaaccacaggccagatagtcaatctgctgtccaatgatgtcaac
aagtttgaccaggtgacagtgttcttacacttcctgtgggcagggccactgcaggcgatc
gcagtgactgccctactctggatggagataggaatatcgtgccttgctggaatggcagtt
ctaattattctcctgcccttccaaagctgtttcgggaagttgttctcatcactgaggagt
aaaactgcaactttcacggatgccaggatcaggaccatgaatgaagttataactggcata
aggataataaaaatgtacgcctgggaaaagtcattttcagatcttgttaccaatttgaga
aagaaggagatttccaagattctgagaagttcctacctcagagggatgaatttggcctca
tttttcagtgcaagcaaaatcatcgtgtttgtgactttcaccacctacatgctcctcggc
aacgtgatcacagccagccgcgtattcgtggccgtgacactgtatggggctgtgcggctg
acggtcaccctcttcttccccgcagccattgagaaggtgtcagaggcaatcatcagcatc
cgaagaatccagaactttttgctacttgatgagatatcacagcgtaaccgtcagccgccg
tcagatggtaaaaagatggtgcatgtgcaggactttactgctttttgggataaggcatca
gagaccccaactctacaaggcctttcctttactgtcagacctggtgaattgttagctgtg
gtcggccccgtgggagcagggaagtcatcactgttaagtgctgtgctcggggaattggcc
cccagtcacgggctggtcagcgtgcatggaagaattgcttatgtgtctcagcagccctgg
gtgttctcgggaactgtgaggagtaatattttatttgggaagaaatatgaaaaggaacga
tatgaaaaagtcataaaggcttgtgctctgaaaaaggatttacagctgttggaggatggt
gatctgactgtgataggagatcggggaaccacgctgagtggagggcagaaagcgcgggta
aaccttgcaagagcagtgtatcaagatgctgacatctatctcctggacgatcctctcagc
gcagtagatgcggaagttagcaggcacttgttcgaactgtgtatttgtcaaactttgcat
gagaagatcacaattttagtgactcatcagttgcagtacctcaaagctgcaagtcagatt
ctgatattgaaagatggtaaaatggtgcagaaggggacttacactgagttcctaaaatct
ggtatagattttggctcccttttgaagaaggacaacgaggaaagcgaacaacttccagtt
ccaggaactcccacgctgaggaatcgcaccttctccgagtcttcggtttggtctcagcaa
tcttctagaccctccttgaaagatggtgctgtggagacccaagacacggagaatgtccca
gttacactctcagacgagaaccgttctgaaggaaaagttggttttcaggcctataagaat
tacttcagagctggtgctcactggattgtcatcattttccttattctcctaaacactgca
gctcaggttgcctatgttcttcaagattggtggctttcgtactgggcaaaccaacaaagt
acgctaaatgtcactgtaaatggaggaggaaatgtaaccaagaagctagatcttaactgg
tacttaggaatttattcaggtttaaccgcagctaccgttctttttggcatagcaagatct
ctgttggtattctacgtccttgttaattcttcacaaactttgcacaacaaaatgtttgag
tcaattctgaaagctccggtattattctttgatagaaatccaataggaagaattttaaat
cgtttctccaaagacattggacacttggatgatttactgccactgacggttttagatttc
atccagacattgctacaagtggttggtgtggtctctgtggctgtggctgtgattccttgg
atcgcaatacccttggttccccttggaatcgttttcatttttcttcggcgatattttttg
gaaacatcaagagatgtgaagcgcctggaatctacaactcggagcccagtgttttcccac
ttatcatcttctctccagggcctctggaccatccgggcatacaaagcagaagagaggtgt
caggaactgtttgatgcacaccaggatttacattcagaggcttggttcttgtttttgaca
acatcccgctggttcgccgtccgtctggatgccatctgtgccatgtttgtcatcgtcgtt
gcctttgggtccctgattctggcaaaaactctggatgccgggcaggtgggcttggcgctg
tcctacgccctcacactcatggggatgtttcagtggtgtgttcgacaaagtgccgaagtt
gagaatatgatgatctcagtagaaagagtgattgaatacacagaccttgaaaaagaagca
ccttgggaatgtcagaaacgcccgccaccgacctggccccatgaaggagtgatcatcttt
gacaatgtgaacttcatgtacagtctagatgggcctctggtactgaagcatctgacagcg
ctcattaaatcacgagaaaaggttggcattgtgggaagaactggagctggaaaaagttcc
ctcatctcagccctttttagactgtcagaacccgaaggtaaaatttggattgataagatc
ttgacaactgaaattggacttcacgatttaaggaagaaaatgtcaatcatacctcaggaa
cctgttttgttcactggaacaatgaggaaaaacctggatcccttcaatgagcacacggat
gaggaactgtggaatgccttacaagaggtacaacttaaagaaaccattgaagatcttcct
ggtaaaatggatactgaattagcagaatcaggatccaattttagtgtcggacaaagacaa
ctggtatgccttgccagggcaattctcaggaaaaatcagatattgattattgatgaagcg
acggcaaatgtggatccaagaactgatgagttaatacaaaagaaaatccgggagaaattt
gcccactgcaccgtgctaaccattgcacacaggttgaacaccattattgacagcgacagg
ataatggttttagattcaggaagactgaaagaatatgatgagccatatgttttgctacaa
aataaagagagcctattttacaagatggtgcaacaactgggcaaggcagaagccgcggcc
ctcactgaaacagcaaaacaggtatacttcaaaagaaattatccacatattggtcacact
gaccatatggttacaaacacttccaatggacagccctcgaccttaactattttcgagaca
gcactatga |
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