Macaca mulatta (rhesus monkey): 697694
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Entry
697694 CDS
T01028
Symbol
BACE1
Name
(RefSeq) beta-secretase 1 precursor
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
697694 (BACE1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
mcc01002
]
697694 (BACE1)
Enzymes [BR:
mcc01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
697694 (BACE1)
Peptidases and inhibitors [BR:
mcc01002
]
Aspartic peptidases
Family A1: pepsin family
697694 (BACE1)
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Gene cluster
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
Motif
Other DBs
NCBI-GeneID:
697694
NCBI-ProteinID:
NP_001247857
Ensembl:
ENSMMUG00000007785
UniProt:
F7CQI1
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All DBs
Position
14:complement(110348789..110379649)
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AA seq
501 aa
AA seq
DB search
MAQALPWLLLWMGAGVLPAHGTQHGIRLPLRSGLGGAPVGLRLPRETDEEPEEPGRRGSF
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI
DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
HVHDEFRTAAVEGPFVTPDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
RCLRCLRQQHDDFADDISLLK
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atggcccaagccctgccctggctcctgctgtggatgggcgcgggagtgctgcctgcccac
ggcacccagcacggcatccggctgcccctgcgcagcggcctggggggagcccccgtgggg
ctgcggctgccccgggagaccgacgaagagcccgaggagcccggccggaggggcagcttt
gtggagatggtggacaacctgaggggcaagtcggggcagggctactacgtggagatgacc
gtgggcagccccccgcagacgctcaacatcctggtggatacaggcagcagtaactttgca
gtgggtgctgccccccaccccttcctgcatcgctactaccagaggcagctgtccagcaca
taccgggacctccggaagggtgtgtatgtgccctacacccagggcaagtgggaaggggag
ctgggcaccgacctggtaagcatcccccatggccccaacgtcactgtgcgtgccaacatt
gctgccatcactgaatcagacaagttcttcatcaacggctccaactgggaaggcatcctg
gggctggcctatgctgagattgccaggcctgacgactccctggagcctttctttgactct
ctggtaaagcagacccacgttcccaacctcttctccctgcagctttgtggtgctggtttc
cccctcaaccagtctgaagtgctggcctctgtcggagggagcatgatcattggaggtatc
gaccactcgctgtacacaggcagtctctggtatacacccatccggcgggagtggtattat
gaggtgatcattgtgcgggtggagatcaatggacaggatctgaaaatggactgcaaggag
tacaactatgacaagagcattgtggacagtggcaccaccaaccttcgtttgcccaagaaa
gtgtttgaagctgcagtcaaatccatcaaggcagcctcctccacagagaagttccctgat
ggtttctggctaggagagcagctggtgtgctggcaagcaggcaccaccccttggaacatt
ttcccagtcatctcactctacctaatgggtgaggttaccaaccagtccttccgcatcacc
atccttccgcagcaatacctgcggccagtggaagatgtggccacgtcccaagacgactgt
tacaagtttgccatctcacagtcatccacgggcactgttatgggagctgttatcatggag
ggcttctacgttgtctttgatcgggcccgaaaacgaattggctttgctgtcagcgcttgc
catgtgcacgatgagttcaggacggcagcggtggaaggcccttttgtcaccccggacatg
gaagactgtggctacaacattccacagacagatgagtcaaccctcatgaccatagcctat
gtcatggctgccatctgcgccctcttcatgctgccactctgcctcatggtgtgtcagtgg
cgctgcctccgctgcctgcgccagcagcatgatgactttgctgatgacatctccctgctg
aagtga
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