Macaca mulatta (rhesus monkey): 698223
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Entry
698223 CDS
T01028
Symbol
ROCK1
Name
(RefSeq) rho-associated protein kinase 1
KO
K04514
Rho-associated protein kinase 1 [EC:
2.7.11.39
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc04022
cGMP-PKG signaling pathway
mcc04024
cAMP signaling pathway
mcc04062
Chemokine signaling pathway
mcc04071
Sphingolipid signaling pathway
mcc04270
Vascular smooth muscle contraction
mcc04350
TGF-beta signaling pathway
mcc04360
Axon guidance
mcc04510
Focal adhesion
mcc04520
Adherens junction
mcc04530
Tight junction
mcc04611
Platelet activation
mcc04670
Leukocyte transendothelial migration
mcc04810
Regulation of actin cytoskeleton
mcc04921
Oxytocin signaling pathway
mcc05135
Yersinia infection
mcc05163
Human cytomegalovirus infection
mcc05200
Pathways in cancer
mcc05205
Proteoglycans in cancer
mcc05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
698223 (ROCK1)
04071 Sphingolipid signaling pathway
698223 (ROCK1)
04024 cAMP signaling pathway
698223 (ROCK1)
04022 cGMP-PKG signaling pathway
698223 (ROCK1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
698223 (ROCK1)
04520 Adherens junction
698223 (ROCK1)
04530 Tight junction
698223 (ROCK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
698223 (ROCK1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
698223 (ROCK1)
04670 Leukocyte transendothelial migration
698223 (ROCK1)
04062 Chemokine signaling pathway
698223 (ROCK1)
09152 Endocrine system
04921 Oxytocin signaling pathway
698223 (ROCK1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
698223 (ROCK1)
09158 Development and regeneration
04360 Axon guidance
698223 (ROCK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
698223 (ROCK1)
05206 MicroRNAs in cancer
698223 (ROCK1)
05205 Proteoglycans in cancer
698223 (ROCK1)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
698223 (ROCK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
698223 (ROCK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mcc01001
]
698223 (ROCK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mcc03036
]
698223 (ROCK1)
Enzymes [BR:
mcc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
698223 (ROCK1)
Protein kinases [BR:
mcc01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
698223 (ROCK1)
Chromosome and associated proteins [BR:
mcc03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
698223 (ROCK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH
C1_1
Pkinase_C
APH
Motif
Other DBs
NCBI-GeneID:
698223
NCBI-ProteinID:
NP_001248063
Ensembl:
ENSMMUG00000004656
UniProt:
H9EPT5
LinkDB
All DBs
Position
18:61311019..61467663
Genome browser
AA seq
1354 aa
AA seq
DB search
MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYK
DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGEEETFPIPKAFVGNQLPFVGFTYYSNRRYLSSANPNDNRTSSNA
DKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLEST
VSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKL
SQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRLLENSKSQTD
KDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLN
HSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKL
KEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLLLEQES
NKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMR
ELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAE
SEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEETNSMLTKDMEILRRENE
ELTEKMKKAEEEYKLEKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRK
KANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECAHRNELQMQL
ASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSVPNRGNIKRYGWKK
QYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILY
ANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCDACAKPLWHVFKPPPALE
CRRCHVKCHRDHLDKKEDLICPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNP
PSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTS
NT seq
4065 nt
NT seq
+upstream
nt +downstream
nt
atgtcgactggggacagttttgagactcgatttgaaaaaatcgacaacctgctgcgggat
cccaaatcggaagtgaattcggattgtttgctggatggattggatgctttggtatatgat
ttggattttcctgccttaagaaaaaacaaaaatattgacaactttttaagcagatataaa
gacacaataaataaaatcagagatttacgaatgaaagccgaagattatgaagtagtgaag
gtgattggtagaggtgcatttggagaagttcaattggtaaggcataaatccaccaggaag
gtatatgctatgaagcttctcagcaaatttgaaatgattaagagatctgattctgctttt
ttctgggaagaaagggacatcatggcttttgctaatagtccgtgggttgttcagcttttt
tatgcattccaagatgatcgttatctctacatggtgatggaatacatgcctggtggagat
cttgtaaacttaatgagcaactatgatgtgcctgaaaaatgggcacgattctatactgca
gaagtagttcttgcattggatgcaatccattccatgggttttattcacagagatgtgaag
cctgataacatgctgctggataaatctggacatttgaagttagcagattttggtacttgt
atgaagatgaataaggaaggcatggtacgatgtgatacagcagttggaacacctgattat
atttcccctgaagtattaaaatcccaaggtggtgatggttattatggaagagaatgtgac
tggtggtcggttggggtatttttatacgaaatgcttgtaggtgatacacctttttatgca
gattctttggttggaacttacagtaaaattatgaaccataaaaattcacttacctttcct
gatgataatgacatatcaaaagaagcaaaaaaccttatttgtgccttccttactgacagg
gaagtgagattaggacgaaatggtgtagaagaaatcaaacgacatctcttcttcaaaaat
gaccagtgggcttgggaaacactccgagatactgtagcaccagttgtacctgatttaagt
agtgacattgatactagtaattttgatgacttggaagaagataaaggagaggaagaaaca
ttccctattcctaaagcttttgttggcaatcaactaccttttgtaggatttacatattat
agcaatcgtagatacttatcttcagcaaatcctaatgataacaggactagctccaatgca
gataaaagcttgcaggaaagtttgcagaaaacaatctataagctggaagaacagctgcat
aatgaaatgcagttaaaagatgaaatggagcagaagtgcagaacctcaaacataaaacta
gacaagataatgaaagaattggatgaagagggaaatcaaagaagaaatctagaatctaca
gtgtctcagattgagaaggagaaaatgttgctacagcatagaattaatgagtaccaaaga
aaagctgaacaggaaaatgagaagagaagaaatgtagaaaatgaagtttctacattaaag
gatcagttggaagacttaaagaaagtaagtcagaattcacaacttgctaatgagaagctg
tcccagttacaaaagcagctagaagaagccaatgacttacttaggacagaatcagacaca
gctgtaagactgaggaagagtcacacagaaatgagcaagtcaattagtcagttagagtcc
ctgaacagagagttgcaagagagaaatcgacttttagagaattctaagtcacaaacagac
aaagattattaccagctgcaagctatattggaagctgaacgaagggacagaggtcatgat
tctgagatgatcggagaccttcaagctcgaattacatctttacaagaggaggtgaagcat
ctcaaacataatcttgaaaaagtggaaggagaaagaaaagaggctcaagacatgcttaat
cactcagaaaaggaaaagaataatttagaaatagatttaaactacaaacttaaatcatta
caacaacggttagaacaagaggtaaatgaacacaaagtaaccaaagctcgtttaactgac
aaacatcaatctattgaagaggcaaagtctgtggcaatgtgtgagatggaaaaaaagctg
aaagaagaaagagaagctcgagagaaggctgaaaatcgggttgttcagattgagaaacag
tgttccatgctagacgttgatctgaagcaatctcagcagaaactagaacatttgactgga
aataaagaaaggatggaggatgaagttaagaatctaaccctgctactggagcaggaatca
aataagcggctgttgttacaaaatgaattgaagactcaagcatttgaggcagacaattta
aaaggtttagaaaagcagatgaaacaggaaataaatactttattggaagcaaagagatta
ttagaatttgagttagctcagcttacgaaacagtatagagggaatgaaggacagatgcgg
gagctgcaagatcagcttgaagctgaacagtatttctcgacactttataaaacccaggta
aaggaacttaaagaagaaattgaagaaaaaaacagagaaaatttaaagaaaatacaggaa
ctacaaaatgaaaaagaaactcttgctactcagttggatctagcagaaacaaaagctgag
tctgagcagttggctcgaggccttctggaagaacagtattttgaattgactcaagaaagc
aagaaagctgcttcaagaaatagacaagagattacagataaagatcacactgttagtcgg
cttgaagaaacaaacagcatgctaaccaaagatatggaaatattaagaagagagaacgaa
gagctaacagagaaaatgaagaaggcagaggaagaatataaattggagaaggaggaggag
atcagtaatcttaaggctgcctttgaaaagaatatcaacactgagcgaacccttaaaaca
caggctgttaacaagttggcagaaataatgaatcgaaaagattttaaaattgatagaaag
aaagctaatacacaagatttgagaaagaaagaaaaggaaaatcgaaagctacaactggaa
ctcaaccaagaaagagagaaattcaaccagatggtagtgaaacatcagaaggagctgaat
gacatgcaagcgcaactggtagaagaatgtgcacataggaatgagcttcagatgcagttg
gccagcaaagagagtgatattgagcaattgcgtgctaaacttttggacctctcggattct
acaagtgttgctagttttcctagtgctgatgaaactgatggaaacctcccagagtcaaga
attgaaggttggctttcagtaccaaatagaggaaatataaaacgatatggctggaagaaa
cagtatgttgtggtaagcagcaaaaaaattttgttctataatgatgaacaagataaggag
caatccaatccctctatggtattggacatagataaactgtttcacgttagacctgtaacc
caaggagatgtgtatagagctgaaactgaagaaattcctaaaatattccagatactatat
gcaaatgaaggtgaatgtagaaaagatgtagagatggaaccagtacaacaagctgaaaaa
actaatttccaaaatcacaaaggccatgagtttattcctacactctaccactttcctgcc
aattgtgatgcctgtgccaaacctctctggcatgtttttaagccaccccctgccctagag
tgtcgaagatgccatgttaagtgccacagagatcacttagataagaaagaggacttaatt
tgtccatgtaaagtaagttatgacgtaacatcagcaagagatatgctgctgttagcatgt
tctcaggatgaacaaaaaaaatgggtaactcatttagtaaagaaaatccctaagaatcca
ccatctggttttgttcgtgcctcccctcgaacactttctacaagatccactgcaaatcag
tctttccggaaagtggtcaaaaatacatctggaaaaactagttaa
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integrated database retrieval system
