Macaca mulatta (rhesus monkey): 701186
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Entry
701186 CDS
T01028
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc00260
Glycine, serine and threonine metabolism
mcc00630
Glyoxylate and dicarboxylate metabolism
mcc00670
One carbon pool by folate
mcc01100
Metabolic pathways
mcc01200
Carbon metabolism
mcc01230
Biosynthesis of amino acids
mcc01240
Biosynthesis of cofactors
mcc01523
Antifolate resistance
mcc04981
Folate transport and metabolism
Module
mcc_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
701186 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
701186 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
701186 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
701186 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
701186 (SHMT1)
Enzymes [BR:
mcc01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
701186 (SHMT1)
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Gene cluster
GFIT
Motif
Pfam:
SHMT
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
701186
NCBI-ProteinID:
NP_001244360
Ensembl:
ENSMMUG00000013535
UniProt:
F7FV99
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Position
16:complement(18175976..18213528)
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AA seq
483 aa
AA seq
DB search
METPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
INYDQLEENARLFHPKLIIAGTSCYSRNLDYARLRKIADENGAYLMADMAHISGLVVAGV
VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKNVDPKTGKEILYNLESLINSAVFPGL
QGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALMELGYKIVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQK
VAQFIHRGIELTLQIQSDIGVRATLKEFKERLAGDKYQGAVQALREEVESFASLFPLPGL
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NT seq
1452 nt
NT seq
+upstream
nt +downstream
nt
atggagacgccagtcaatggggcccacaaggatgctgacctgtggtcctcacatgacaag
atgctggcacagcccctgaaagacagtgatgttgaggtttacaacatcattaagaaggag
agtaaccggcagcgggttggattggagctgattgcctcggagaatttcgccagccgagca
gttttggaggccctaggctcttgcttaaataacaaatactctgaggggtacccgggccag
agatactatggcgggactgagtttattgatgaactggagaccctctgtcagaagcgagcc
ctgcaggcctataagctggacccacagtgctggggggtcaacgtccagccctactcaggc
tcccctgcaaacttcgctgtgtacactgccctggtggaaccccatgggcgcatcatgggc
ctggacctgccagatgggggccacctgacccatgggttcatgacagacaagaagaaaatc
tctgccacgtccatcttctttgaatctatgccctataaggtgaacccagacactggctac
atcaactatgaccagctggaggagaacgcacgcctcttccacccgaagttgatcatcgca
ggaaccagctgctactcccgaaacctggactatgcccggctgcggaagattgcagatgag
aacggggcatatctcatggcggacatggcacacatcagtgggctggtggtggctggcgtg
gtgccctccccatttgaacactgccacgtggtgaccaccaccactcacaagaccctgcga
ggctgccgagctggcatgatcttctacaggaaaggagtgaaaaatgtggatcccaagact
ggcaaagagattctgtacaacctggagtctcttatcaattctgctgtgttccctggcctg
cagggaggtccccacaaccacgccattgctggggttgctgtggccctgaagcaagctatg
actctggaatttaaagtttatcagcaccaggtggtggccaactgcagggctctgtctgag
gcactgatggagctgggctacaaaatagtcacaggtggttctgacaaccatttgatcctc
gtggatctccgttccaaaggcacagacggtggaagggctgagaaggtgctagaagcctgt
tctattgcctgcaacaagaacacctgcccaggtgacagaagtgctctgcggcccagtgga
ctgcggctggggaccccagcactgacgtctcgtggacttttggaaaaagacttccaaaaa
gtagcccagtttattcacagagggatagagctgaccctgcagatccagagcgacattggt
gtcagagccaccctgaaggagttcaaggagagactggcaggggataagtaccagggggcc
gtgcaggctctccgggaggaggttgagagcttcgcctctctcttccctctgcctggcctg
cccgacttctaa
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