Macaca mulatta (rhesus monkey): 701758
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Entry
701758 CDS
T01028
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc00562
Inositol phosphate metabolism
mcc01100
Metabolic pathways
mcc04014
Ras signaling pathway
mcc04015
Rap1 signaling pathway
mcc04020
Calcium signaling pathway
mcc04024
cAMP signaling pathway
mcc04070
Phosphatidylinositol signaling system
mcc04919
Thyroid hormone signaling pathway
mcc04933
AGE-RAGE signaling pathway in diabetic complications
mcc05205
Proteoglycans in cancer
Module
mcc_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
701758 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
701758 (PLCE1)
04015 Rap1 signaling pathway
701758 (PLCE1)
04020 Calcium signaling pathway
701758 (PLCE1)
04070 Phosphatidylinositol signaling system
701758 (PLCE1)
04024 cAMP signaling pathway
701758 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
701758 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
701758 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
701758 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mcc04131
]
701758 (PLCE1)
Enzymes [BR:
mcc01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
701758 (PLCE1)
Membrane trafficking [BR:
mcc04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
701758 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
701758 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
701758
NCBI-ProteinID:
XP_015003197
UniProt:
F7GTK6
LinkDB
All DBs
Position
9:94144179..94492657
Genome browser
AA seq
2317 aa
AA seq
DB search
MTSEEITASVLIPVTQRKVVSAQSAADESSEKVSDINISKAHTVRQSGETSHTISRLNKL
KEEPSGSNLPKILSITREKIVSDENSNEKCWEKSMPDSVKNLNINCNNILRNHQHGLPQR
QFYEMYNSVVEEDLCLETGILSPLERKVFPGIQLELDRPSMGINPLGNQSAIIETGRADP
DSSTAVFHFHYEVDRRMSDTFCTLSENLILDDCGNCVPLPGGEEKQKENYMAYTCKLMEL
AKNCDNKNEQLQCDHCDTLNDKYFCFEGSCQKVDMVCSSHSFCKEDFTDSQTAKTFLSHF
EDFPDNCEDVEEDAFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLIA
WSYIDQKRNGPLLPCGRVMEPLSTVEIKQGGSRRLSEAQWYPIYNAVRRGEETENTVGSL
LHFFTKLPASETAHGRISVGPCLKQCVRDTVYEYRATLQRTSISQYITGSLLEATTSLGA
RSGLLSTFGGSTGRMMLKERQPGPSVANSNTLPSSSAGISKELIDLQPLIQFPEEVASIL
MEQEQSIYRRVLPVDYLCFLTRDLGTPECQRSLPCLKASISASILTTQNGEHNALEDLVM
RFNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKM
WQFMDQSDIETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDG
ASGLMKICPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQVIRSCSR
SLETDEEDSPSEGNSSRKSSLKDKSRWQFIIGDLLDSDNDIFEQSKEYDSHGSEDSQKAF
DHGTELIPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWVKPTTA
SPASTKAKLGVLNNTAEPGKFPLLGNAGLSGLTEGVLDLFAVKAVYMGHPGIDIHTVCVQ
NKLGSMFLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQR
QQWLRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSARNPSPGTSAKNAEKPSMQRNNTL
GISTTKKKKKILMRGESGEATDDEMATRKAKMHKECRSRSGSDPQDINEQEESEANTIAS
PPNPLPSRRAHSLTTAGSPNLAAGTSSPIRPVSSPVLPSSNKSPSSAWSSSSWHGRIKGG
MKGFQSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDVYAVPCSRSGSESAPLYTNLM
IDENTSDLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSL
GIFGVGILQLNDFLVNCQGEHCTYDEILSIIQKFEPNISMCHQGLMSFEGFARFLMDKEN
FASKNDESQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELD
CWDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAE
IFKTVFGEKLVAKFLFETDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQL
ASMQAQAYNGGNANPPPANNEEEEDEEDEYDYDYESLSDADVLTASPAPNGQEDNILEDR
PENKSCSDKLQFEYSEEIPKRIKKADNSACNKGKVYDMELGEEFYLDQNKKESRQIAPEL
SDLVIYCQAVKFPGLSTLNASGSNRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSC
EGIRQTWEESSSPLNPTTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLL
RTYPAATRIDSSNPNPIMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVL
WDKNCPMYQKFSPLERDLDSMDPVVYSLTIVSGQNVCPSNSTGSPCIEVDVLGMPLDSCH
FRTKPIHRNTLNPMWNEQFLFRVHFEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRH
LQLRNLHNEVLEISSLFINSRRMEENSSGSPMSASSMFTTEERKCLQTHRVTVHGVPGPE
PFTVFTINGGTKAKQLLQQILTTEQDIKPVTTDYFLMEEKYFISKEKNECRKQPFQRAIG
PEEEIVQILSSWFPEEGYVGRILLKTQQENLEEKNIVQDDKEVILSSEEESFFVQVHDVS
PEQPRTVIKAPRVSTAQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTTNKKSTTP
KSSQRVLLDQECVFQAQSKWKGAGKFILKLKEQVQASREDKKKGISFASELKKLTKSTKQ
PRGLTSPSQLLTSESIQTKEEKPVGGLSSSDTMDYRQ
NT seq
6954 nt
NT seq
+upstream
nt +downstream
nt
atgacttctgaagaaattacagcttctgttctcatacctgtgactcagagaaaagtggtt
tctgcccagtcagctgcagatgaaagtagtgaaaaggtctcagacatcaatatttcaaaa
gcacatactgtcagacaaagtggggagacttctcataccatctcacgactgaacaaactt
aaagaagaaccttctggaagcaacttgccaaagattctctcaataacaagggagaaaata
gtgagtgatgagaacagtaatgaaaaatgctgggagaaaagcatgccagattctgtgaaa
aaccttaacattaactgcaacaacatattgagaaaccatcagcatggccttcctcaaaga
cagttttatgaaatgtacaactctgttgttgaggaagacctgtgtttagaaactggaatt
ctgtctccactggaaagaaaggtgttccctggaattcaactggaactagacagaccttcc
atgggcattaatcctttaggaaatcagtcagcaatcatagagacaggcagagcagaccct
gacagcagcacggcagtatttcattttcattatgaagttgacagaagaatgtcagacact
ttctgtaccctatcagaaaacttaattttagacgattgtggaaattgtgtaccactacct
gggggtgaggagaagcaaaaggaaaactacatggcatatacctgtaaactgatggaattg
gccaaaaattgtgataataagaatgaacagctgcagtgtgatcattgtgacaccttgaat
gataaatacttttgctttgaaggctcttgccagaaggtggacatggtatgttcaagtcat
agcttttgtaaggaagattttactgacagtcaaactgccaagacctttttgagtcatttt
gaggatttccctgataattgtgaagatgtagaagaagatgcttttaaaagcaaaaaggag
cggtccactttgttagtcaggagattctgtaaaaatgacagagaagttaagaaatctgtg
tataccggcacaagagcaattgtgaggactctgccttctggccacattgggctgattgca
tggagttacatagatcagaagagaaatggtcccttactgccttgtgggagagtaatggaa
cccctatcaacagtggagataaagcaaggtgggagccgacgtctgtcagaagcccagtgg
tatcctatctacaatgcagtgagaagaggagaagaaacagaaaatacagttggatctcta
ctccatttcttcaccaagctcccagcctccgagacagcccatggaagaataagtgttggt
ccatgcttaaagcaatgtgtccgagacactgtatatgagtatcgcgccaccctccaaagg
acttcaatatcgcagtacatcaccggttctctcctagaagcaaccacatctttgggagca
agaagtggccttctcagtacttttggaggatccactggacgaatgatgctgaaagaacgc
cagccaggcccctctgtggccaattccaacaccctcccttcaagttcagctgggatcagc
aaggagctgatcgatctgcagcctctcatccagttcccagaggaagtcgccagcatcctg
atggagcaggagcagagtatttaccgcagggtcttgccggtcgactacctttgcttctta
acacgggacttgggcactcccgaatgccagaggtccctgccctgcctcaaagcatccatc
tcagcgtcaattcttaccactcagaatggagagcacaatgcccttgaagatctggtgatg
aggtttaatgaggtgagctcctgggtgacgtggctgatcctcacggcaggctccatggag
gagaagcgagaagtcttttcatatttggtgcatgtggccaagtgctgctggaacatgggc
aactacaacgctgtcatggagttcttggctggcctcaggtcaagaaaagttttaaaaatg
tggcagtttatggaccagtctgatattgagaccatgaggagcctgaaggatgctatggcc
cagcatgagtcctcttgtgagtacagaaaggtggtgacacgtgccctgcacatccctggc
tgtaaggtggttccgttctgtggagtgtttcttaaggagctctgtgaagtgcttgacggc
gcctctggcctcatgaagatatgcccgcggtacaattcccaagaagaaactttagagttt
gtagcagattacagtggacaagataatttcttacaacgagtgggacaaaatggcttaaag
aattcggagaaggagtccactgtcaacagcatctttcaggtcatccggagctgcagtcga
agtctggagacagacgaggaggacagccccagtgaagggaacagctccaggaaaagttcc
ttgaaggataaaagccgatggcagtttataattggagatttgttggattcagacaatgat
atctttgagcaatccaaagaatacgactctcatggttcagaggactcacagaaggccttc
gaccatggaacggagctcatcccatggtatgtgctgtccatccaagccgatgtgcaccag
ttcctgctgcagggtgccacggtcatccactacgaccaggacacacacctctctgcccgc
tgcttcctccagcttcagcctgacaatagcaccttgacctgggtaaagcccacaactgcc
tccccagccagcactaaagcaaaacttggtgtacttaataacacagctgagcctggaaaa
ttcccactactgggcaatgctggattaagtggcctgacggaaggggtcttggatcttttt
gcagtgaaggctgtatacatgggccaccctggcattgatatacacactgtgtgtgttcag
aacaaactgggtagcatgttcctgtcagagactggtgtgacactgctctatgggcttcag
accacagacaatagattattgcacttcgtggcaccaaagcacacagctaaaatgctcttc
agcggattgttggaactcactagagctgtgagaaagatgaggaaattccctgaccaaaga
cagcagtggctgcggaaacagtacgtcagcctctatcaggaggatggacggtatgaaggc
ccaactttggctcatgctgtggagttgtttggtggcagacgatggagtgctcgaaacccc
agccccggcacatctgcaaagaatgctgagaagcccagtatgcagagaaacaacaccctg
ggcataagcactaccaagaaaaagaagaaaatcctcatgaggggtgagagtggagaggca
actgacgacgagatggcaacccgaaaggccaagatgcacaaagagtgtcgaagccggagt
ggttctgatcctcaagacattaatgaacaagaagaatcagaggcgaataccatcgctagc
ccgccaaaccccctcccttccagaagagcccactctttgaccacagctgggtcccccaac
ttggctgccgggacgtcatctcccatcaggccagtgtcctcccctgtgctgccttcttca
aacaagagcccgtccagtgcttggagcagtagtagctggcacggacggatcaaaggcggc
atgaagggatttcagagcttcatggtttcagacagcaacatgagttttgttgaatttgtt
gagctgttcaaatcgttcagtgtcaggagccgcaaggacctgaaggatctgtttgatgtc
tatgcagtgccctgcagccgatctggatccgagtcagccccgctctacaccaacttgatg
attgatgaaaacaccagcgatcttcagcctgacctagatctgttgaccagaaatgtctca
gatttggggttgttcatcaagagtaaacagcagctatcagacaaccagaggcagatatct
gatgccattgctgctgcaagcatcgtgacaaatggcactgggattgagagcacatctctg
ggcattttcggggtgggcatacttcagctcaacgatttcctcgtgaattgccaaggagaa
cactgcacttatgatgaaatcctcagcatcatccagaagtttgagcctaacatcagtatg
tgtcatcagggactaatgtcatttgaagggtttgcaaggtttctgatggataaagaaaat
tttgcctcaaaaaatgatgagtcacaggagaacattaaagaactgcagctacccctctca
tactattacatcgaatcttcgcacaatacctacctcacgggccatcagctcaaaggagaa
tcctcggtagaactctacagccaggtcctcttgcaaggctgtcgaagtgtagaattggac
tgctgggacggagacgatgggatgcccatcatttatcatggacatacactgacaaccaag
atccccttcaaggaagtggttgaagccattgatcgcagtgccttcatcaactctgacctg
ccaatcatcatatcgattgagaaccactgttcattgcctcagcaacgaaaaatggcagaa
attttcaagactgtgtttggagaaaagctggtggctaaattcttatttgagactgatttc
tcagatgatccaatgcttccttcacctgaccaactcagaaggaaagtgcttcttaaaaac
aagaaactaaaagcccatcagacgccagtggatatcttaaagcaaaaggctcatcagtta
gcatctatgcaagcgcaggcttataatggtgggaatgccaaccccccacctgccaataat
gaggaagaggaagatgaggaggacgaatatgattatgactatgaatccctttctgatgca
gatgtccttactgcctcccctgctcctaacggtcaggaagacaacattctggaagacaga
cctgaaaataaatcatgtagtgacaagcttcagtttgagtatagtgaagaaatccccaag
aggataaagaaggcagataactctgcttgcaacaaaggaaaggtttatgatatggaactg
ggagaagaattttatcttgatcagaataaaaaggaaagcagacagattgcaccagagctt
tctgaccttgtaatctattgtcaagcagtaaaatttccaggactgtcaactctaaatgca
tctggctctaacagaggaaaggaaaggaaaagcaggaagtccatttttggcaacaatccg
ggcagaatgagcccaggggagacagcatcatttaacaaaacatctggaaaaagttcctgt
gaaggcattcgacagacctgggaggaatcttcttcccctctcaacccaaccacgtccctc
agtgctatcattagaactcctaaatgttatcatatctcgtcgctgaatgaaaatgccgcc
aaacgtctgtgtcgcaggtattctcagaaactgatccagcataccgcctgtcagctgctg
agaacttaccctgctgccactcgcatcgactcctccaacccaaaccccatcatgttctgg
ctccatgggatacagctcgtggcactcaactaccagaccgatgatctccctttacattta
aatgctgcaatgtttgaggcaaatggtggttgtggttatgttttgaaacctccagttctg
tgggacaagaactgcccgatgtatcagaagttttctccactggaaagagatttggacagc
atggatcctgtagtctattctttaactattgtctctggtcagaatgtgtgccccagtaac
agcacgggaagcccgtgcattgaagtcgacgtcctgggcatgcctctggacagctgccat
ttccgcacaaagcccatccatcgaaacaccctgaaccccatgtggaacgagcagtttctg
ttccgcgttcacttcgaagatcttgtatttcttcgttttgcagttgtggaaaacaacagt
tcagcggtaactgctcagagaatcattccactgaaagctttaaaacgaggctatcgacat
cttcagctgcgaaaccttcacaatgaagtcttggagatctctagtttattcattaacagc
agaaggatggaagaaaattcctctggcagtcccatgtcagcctcttcgatgtttactaca
gaagaaagaaaatgtttgcagactcacagagtcacggtgcatggggtcccagggccagag
ccctttactgttttcactattaatggaggcaccaaggcaaagcagcttctgcagcaaatt
ctgacaactgaacaagacatcaaacctgttaccacagactattttttgatggaagaaaaa
tattttatatctaaagaaaagaatgaatgcaggaaacaaccattccagagagccattggt
ccagaagaggagatcgtgcaaattttaagcagctggtttccagaagagggatatgtgggc
aggattctcttaaaaacccagcaggaaaacctagaagagaaaaacattgttcaagatgac
aaagaggtgatcttgagctcagaggaggagagtttctttgtccaagtgcatgatgtttct
ccagagcaacctcgaacagtcatcaaagcaccccgcgtcagcaccgcacaggatgtcatt
cagcagaccttatgcaaagccaaatattcctacagcatcctgagcaaccccaatccaagt
gactatgtgcttctggaagaggtggtgaaagacactaccaacaagaagtctaccacaccc
aagtcctctcagcgggtccttctggatcaggagtgtgtgtttcaagcccaaagcaagtgg
aaaggtgcaggaaaattcatccttaagctaaaggagcaggtgcaggcatctcgagaagac
aaaaagaaaggcatttcttttgcaagtgaactcaagaagctcaccaagtcaactaaacag
ccccgaggacttacatcaccttctcagctcttgacctcagaaagtatccaaaccaaggag
gagaaacctgtgggtggcttgtcctccagtgacacaatggattaccgacagtga
DBGET
integrated database retrieval system
