Macaca mulatta (rhesus monkey): 703422
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Entry
703422 CDS
T01028
Symbol
ARHGEF4
Name
(RefSeq) rho guanine nucleotide exchange factor 4
KO
K05769
Rho guanine nucleotide exchange factor 4/29
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc04810
Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
703422 (ARHGEF4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mcc04131
]
703422 (ARHGEF4)
Membrane trafficking [BR:
mcc04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
703422 (ARHGEF4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RhoGEF
PH
SH3_1
SH3_9
SH3_2
Motif
Other DBs
NCBI-GeneID:
703422
NCBI-ProteinID:
XP_028686422
LinkDB
All DBs
Position
12:593215..802601
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AA seq
1864 aa
AA seq
DB search
MLSVVHFLRSFFKTPEPDAHLPGEGEIEDNQLPTSPVEQVEQGWSRQTDRDDSETLSQQS
ETGSDTKTDPFESASDTESLSGDLPRGVFHPLRGTPVDTEVPWEYPDVSATGPPQEQHLT
SVPGLHAKEELGLSPGLKDDSCKNGWRAFATVAGEQEAGHLWDCATSLEREALLAGAPRH
TGCCLQRATDSSGPEPERGVAIQDLRGLSAVSLQKSRSEGYLGIPVVWPFLLWCCELGRS
WPHIHNRARALVPLSRDPVDSTAPLGTRTKRESTLSLAGDTELLWSQPHLDVPCQPPLRT
SCLLHTKRHHSAPETIGDKNRASPIHDCGHLRAPVRAHSIAGFSSECPEDPMGPNVVKSG
TPVKEGEENERDPRTQNALSPTPTPLAGPLPAFQSGAPHLQGPCKPDGFRLQRAFQDTPS
ADLLGENQLRQESRSCLVASCLTSELVKLSAEEVPEPAEYKSEQSPESRTQEPQGTQLAP
RAAAERQTQKHLWGISVEAGNQTSNFTSKYVLGVESKPPTRAKFPRQPSSQGTQVWSGDS
MGCLEVSDSSDAPETTQKSSAIDTSKAAEEAMFLDPNFREQALQGLSEFKAATVSHCGPG
AEEGEQGPGGAVGRQLEPKAGGEASRGRGALIIVAVEQKGLQAARSNARPVPEALPPRFP
EERPESPPSTGETACESPATGKTPAGKECELLQPVAQAAELGSVLVPRAALVEKPSTAAP
PGETLRGESQSPGPGERGAGEAPEGGAAAAPGQRPRIPALEPPQPPRGLRKAVQEPGKRP
TFSKVTSFRKGRPLAAESPGGDPAPTTEGRGGGLSGPEGLPPENLPRAARWDPPPLHHGD
ASAWPEFAPQAAGDGTAGPAGTGHMGTAGDLGRRGPSSESCNAKRLKTTEKKLRARLALA
HKTFSSFFESIVVEKENTQERSPGSPKGEKEKSRLRQGSWRAFLKSKDTESPKKPALVRP
LLGPGILSPAETDSHCEERAGDKEGYVFSDHWAPPLAPTPLPPSLVSPERRRKSEPTIKC
TAAREGGRYLPSGIFPEKSWLVSPGSPRAQQAGIAHTLPSSSASYLAYENPGTPCRPTSP
KPLSPRPNAQRTGPHYPGRGSAVSMVSLGSYSYVDSSSGDPERPKIPKGRTSLLLSLQTL
NQDEQKEEGREGGPGPRGLGTAPWLRDLPGNENHMPWEEPASEKPSCSHIRKAFHMEPAR
KPCFTTEMVTWALLCVSAEAVHGEAHSQPRGIPHRSPISVDDLWLEKTQRKKLQKQAHVE
RSLHVGAVHKDGVKCWRKTIITSPESLNLRRRSRPLSQSAPTGLNHMGWPEHIPGTAMPD
GALDTAVRADEVGSEEDLYDDLHSSGHHYSHPGGGGEQLAINELISDGSVVCAEALWDHV
TMDDQELGFKAGDVIEVMDATNREWWWGRVADCEGWFPASFVRLRVNQDEPADDEAPRAR
DGGAEDGGAEAQSSKDQMRTNVINEILSTERDYIKHLRDICEGYVRQCRKRADMFSEEQL
RTIFGNIEDIYRCQKAFVKALEQRFNRESPHLSELGACFLEHQADFQIYSEYCNNHPNAC
VELSRLTKLSKYVYFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHR
DFKDVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIYSGEL
TRVTQPQAKSQQRMFFLFDHQLIYCKKDLLRRDVLYYKGRLDMDGLEVVDLEDGKDRDLH
VSIKNAFRLHCGATGDSHLLCTRKPEQKQRWLKAFAREREQVQLDQETGFSITELQRKQA
MLNASKQQVTGKPKAVGRPCYLTRQKHPALPGSRPQQQVLVLAEPRRKPSTFWHSISRLA
PFRK
NT seq
5595 nt
NT seq
+upstream
nt +downstream
nt
atgctcagcgtcgtgcacttcctccggagcttcttcaagactccagagccagatgcacac
ctgccaggtgaaggtgagattgaagataaccagctccccacatcccctgtggaacaagtg
gagcagggatggagccggcagacagaccgcgatgattctgaaacactgtcccagcagagt
gaaactggatcagacacaaaaactgacccctttgaaagtgcctccgacacagagtccttg
tctggggacctcccgaggggagtcttccaccctctgagaggtacccctgtagacacagaa
gtgccttgggaataccctgatgtctcagcaactggaccccctcaagagcagcatttgacc
agtgttcctgggcttcatgcaaaggaagaactcggtttgtcccctggcttaaaggacgac
tcttgcaaaaatgggtggcgagcctttgccaccgttgctggagaacaggaggcaggacac
ctctgggactgcgcgacgagcctggagcgagaggctttgctggcaggggctccccgacac
acagggtgctgcttacagagggccacagacagcagcggtccggagccagaacggggggtg
gctattcaagacctcagagggctctccgctgtctctcttcagaaatccaggtctgagggc
tatctgggcatcccagtggtctggcccttccttctctggtgctgtgaactgggtcggagt
tggccacatatccacaacagggccagggcacttgtgccacttagcagagacccagtggac
agcacagcccctctggggaccaggacaaaaagggaaagtactctaagccttgcaggggac
acagaactgctctggtcccagccccacttggatgttccctgccagcctcctttgagaaca
tcttgccttctacacaccaagcgtcatcatagtgccccagaaactattggtgacaagaat
agggcatcccccatacacgactgtgggcacttgagggcaccggtcagggcccattccata
gcagggttttcctcagagtgccccgaggatcccatgggaccgaatgttgtgaagtctggc
acccctgtgaaggaaggggaagaaaatgaacgagatccaagaacacaaaacgccctttcc
cctacacccaccccgctggctggcccgcttcctgcttttcaaagtggggctccgcatctg
cagggtccctgcaagcccgatgggtttcgcttgcaaagggcctttcaggacactccttct
gcagatctcctgggggaaaaccagttaagacaggaatccaggtcatgtctggtggcttca
tgcctcacgtcagagttagtgaagctcagtgcggaggaagtgcctgagcctgctgagtac
aagtcggagcaaagcccagaaagcagaacccaggaaccccaaggcacccaactcgcacca
agagctgctgctgagagacagacacagaagcacctctggggcatttctgtcgaggcagga
aaccaaaccagtaatttcacatcaaagtatgtgctcggcgtggaaagcaagccacctacc
agggccaagttcccacggcagcctagcagtcaggggacccaggtgtggagtggagactca
atgggctgcttggaagtgagtgacagttcagatgcccctgagaccacccagaagtcaagc
gcaatagacacttcaaaggcagccgaagaggccatgtttctagaccccaatttcagggaa
caggctttgcaaggtctttcagaattcaaggcagccacggtgtctcactgcggccctggg
gctgaggagggtgaacaggggcctgggggtgccgtgggccggcagctggagcccaaagca
ggcggtgaggcctccaggggcaggggcgccctcatcattgtggctgtggagcagaaaggt
cttcaggccgccaggagcaatgcgaggcctgttccagaagcactgccccctcgctttcct
gaggaaagaccggaatctcccccgagcactggcgagaccgcctgtgagtctcccgctacg
gggaaaacaccagccggtaaagagtgtgagctgcttcagcccgtggcccaggccgcagag
ctcgggagcgtgctggttccccgagctgctttggtggagaagccgagcacagcggcgccc
ccgggagagacactgcgtggggagagccagagccccgggcccggggagcgtggcgccggg
gaggccccggagggcggcgctgcagcagccccgggccagcgcccgcgtatccctgccttg
gagccgccccagccgccacgcgggcttcgcaaggccgtgcaggaacctgggaagcgcccc
acgttttccaaggtgacctccttcaggaagggcaggcccttggccgctgagagcccagga
ggggacccggccccgaccaccgagggccgcggcgggggtctttcaggccccgaggggctc
cccccggagaatctgccccgggcggcccgctgggacccgccgcctctgcaccacggggac
gccagcgcctggcccgagtttgccccgcaggctgcaggcgacgggaccgcagggccggca
gggactgggcacatggggaccgcaggggaccttggtaggcgagggccttcctctgagagc
tgtaacgcaaagagactcaaaacaacggagaaaaagctcagggcaaggttagccttggct
cataagaccttttcaagcttttttgagtcaatcgttgtagagaaagagaacacccaggaa
cgttccccaggttctcccaagggcgagaaggagaagagcaggctgcgccagggttcctgg
cgggcctttctgaaaagcaaagacaccgaaagccccaaaaagcccgccctagtgagaccg
ctgctaggacccggaattctttccccggcagagaccgacagccactgtgaggaacgggcg
ggggacaaagagggctatgtttttagcgatcactgggcacccccacttgcccccacacct
ttgccccccagtttagtttctccagaacgcaggaggaaaagtgaaccgaccatcaagtgc
acagccgcccgggaaggcggtaggtacctaccttcaggtatctttcctgaaaagtcctgg
ctggtgtcccccggcagccctcgggcccagcaggctggcatcgcgcacaccctgccttcc
agctctgccagctacctggcatatgaaaaccccgggacgccctgcagacccacgagcccc
aaacccctgagtcccaggcctaatgctcagcggacgggtccccactaccccgggaggggt
agcgccgtctccatggtttctcttggaagctacagctacgtggacagcagttcaggggac
cctgaaagacccaagattcccaagggccggaccagtctcctgctttctctgcagacgcta
aaccaggatgagcagaaggaagagggcagggaaggaggcccgggtccacgcggcttgggc
acagcgccctggctcagggaccttcctgggaatgagaaccacatgccctgggaagaacca
gcaagtgagaagcccagttgctctcacattcggaaggctttccacatggagcctgcccgg
aagccctgcttcaccactgagatggtgacatgggccctcctctgcgtctctgcagaggct
gtgcacggggaggctcattcacagcctaggggcatccctcaccgctcacccatcagtgtg
gatgacctgtggctggagaagacacagagaaagaagttgcagaagcaggcccacgtcgaa
aggagtctgcatgtaggggcagtgcacaaagatggagtcaagtgctggagaaagacgatc
attacctctccagagtctttgaatctccgtagaagaagccgtccactctcccagagtgct
ccaacgggactgaaccacatgggctggccagagcacatacctggcactgccatgcctgat
ggagctctggacacagctgtccgcgctgatgaagtggggagcgaggaggacctgtatgat
gacctgcacagctccggccaccactacagccaccctggagggggtggtgagcagctggct
atcaatgagctcatcagcgatggcagtgtggtctgcgctgaagcactctgggaccatgtc
accatggatgaccaggagctgggtttcaaagctggggatgtcatcgaagtgatggatgcc
accaacagagagtggtggtggggccgggtcgccgactgcgagggctggtttccagccagc
ttcgttcggctgcgggtgaaccaggacgagcccgcggacgacgaggcccctcgggccagg
gacggcggggcggaggacggcggggcggaggcgcagagcagcaaggaccagatgcggacc
aacgtcatcaacgagattctcagcaccgagcgggactacatcaagcacctgcgcgacatc
tgcgagggctacgtccgccagtgccgcaagcgcgcagacatgttcagcgaggagcagctg
cgcaccatcttcgggaacatcgaggacatctaccgctgccagaaggccttcgtgaaggcc
ctggagcagaggttcaaccgcgaaagcccgcacctgagcgagctgggtgcctgcttcctg
gagcatcaagccgacttccagatctactcggagtactgcaataaccaccccaacgcctgc
gtggagctctcccggctcaccaagctcagcaagtacgtgtacttcttcgaggcctgccgg
ctgctgcaaaagatgattgacatctccctggatggcttcctgctgactccggtgcagaag
atctgcaagtaccctctgcagctggccgagctgctcaaatacacgcacccccagcacagg
gacttcaaggacgttgaagctgccttgcatgccatgaagaatgtggcccagctcatcaac
gagcggaagcggagacttgagaacatcgacaagattgctcagtggcagagctccatagag
gactgggagggtgaagatctcttggtcaggagctcagaactcatctactcgggggagctg
actcgagttacgcagcctcaagccaagagccagcagagaatgttctttctctttgaccac
cagctcatctactgtaagaaggacctgctgcgccgcgacgtgttgtactacaagggccgg
ctggacatggacggcctggaggtggtggacctggaggacgggaaggacagagacctccat
gtgagcatcaagaacgccttccggctgcactgtggcgccacaggggacagccacctgctg
tgcaccaggaagcccgagcagaagcagcgctggctcaaggcctttgccagggagagggag
caggtgcagctggaccaggagacaggcttctccatcactgaactgcagaggaagcaggcc
atgctgaatgccagcaagcagcaggtcacagggaagcccaaagctgttggccggccctgc
tacctgacgcgccagaagcacccagccctgcccggcagccggccccagcagcaggtcctg
gtgctggcggagcccaggcggaagccatctaccttctggcacagcatcagccggctggca
cccttccgcaagtga
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