Macaca mulatta (rhesus monkey): 705676
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Entry
705676 CDS
T01028
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc00140
Steroid hormone biosynthesis
mcc01100
Metabolic pathways
mcc05215
Prostate cancer
Module
mcc_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
705676 (SRD5A2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
705676 (SRD5A2)
Enzymes [BR:
mcc01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
705676 (SRD5A2)
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Motif
Pfam:
Steroid_dh
DUF1295
DUF6832
PEMT
Motif
Other DBs
NCBI-GeneID:
705676
NCBI-ProteinID:
XP_001105329
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Position
13:77309668..77368348
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AA seq
284 aa
AA seq
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MGWRLALHKGVAGAALSSARAAATGEEHGAMQVQCQQSPVLAGSATLVALGALVLYVAKP
SGYGKHTESLKPAATRLPARAAWFLQELPSFAVPAGILARQPLSLFGPPGTVLLGLFCVH
YFHRTFVYSLLNRGRPYPAVLIFRGIAFCAGNGFLQSYYLIYCAEYPDGWYTDIRFCLGV
FLFILGMGVNIHSDYILRQLRKPGEITYRIPQGGLFTYVSGANFLGEIIEWIGYALATWS
LPALAFAFFSVCFLGLRAFHHHRFYLKMFEDYPKSRKALIPFIF
NT seq
855 nt
NT seq
+upstream
nt +downstream
nt
atggggtggcgtctggcgctccataaaggggttgcgggggccgcgctctcttctgctagg
gcagcggccaccggcgaggaacacggcgcgatgcaggttcagtgccagcagagcccagtg
ctggcaggcagcgccactttggtcgcccttggggcactggtcttgtacgtcgcgaagccc
tccggctacgggaagcacacggagagcctgaagcccgcggctacccgcctgccagcccgc
gcagcctggttcctgcaggagctgccctccttcgcggtgcccgcggggatcctcgctcgg
cagcccctctccctcttcgggccacctgggacggtgcttctgggcctcttctgcgtacat
tacttccacaggacatttgtgtactcactgctcaatcgagggaggccttatccagctgta
ctcattttccgaggcattgccttctgcgctggaaatggattccttcaaagctactatctg
atttactgtgctgaataccctgatgggtggtacacagacatacggttttgcttgggtgtc
ttcttatttattttgggaatgggagtcaacatccatagtgactatatattgcgccagctc
aggaagcctggagaaatcacctacaggattccacaaggtggcttgtttacgtatgtttct
ggagccaatttccttggtgagatcattgaatggatcggctatgcgctggccacttggtcc
ctcccagcacttgcatttgcatttttctcagtttgtttccttgggctgcgagcttttcac
caccataggttctacctcaagatgtttgaggactaccccaaatctcggaaagcccttatt
ccattcatcttttaa
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