Macaca mulatta (rhesus monkey): 707977 Help Entry 707977            CDS       T01028                                  Symbol KRAS Name (RefSeq) GTPase KRas   KO K07827   GTPase KRas Organism mcc  Macaca mulatta (rhesus monkey) Pathway mcc01521   EGFR tyrosine kinase inhibitor resistance mcc01522   Endocrine resistance mcc04010   MAPK signaling pathway mcc04012   ErbB signaling pathway mcc04014   Ras signaling pathway mcc04015   Rap1 signaling pathway mcc04062   Chemokine signaling pathway mcc04068   FoxO signaling pathway mcc04071   Sphingolipid signaling pathway mcc04072   Phospholipase D signaling pathway mcc04137   Mitophagy - animal mcc04140   Autophagy - animal mcc04150   mTOR signaling pathway mcc04151   PI3K-Akt signaling pathway mcc04210   Apoptosis mcc04211   Longevity regulating pathway mcc04213   Longevity regulating pathway - multiple species mcc04218   Cellular senescence mcc04360   Axon guidance mcc04370   VEGF signaling pathway mcc04371   Apelin signaling pathway mcc04540   Gap junction mcc04550   Signaling pathways regulating pluripotency of stem cells mcc04625   C-type lectin receptor signaling pathway mcc04650   Natural killer cell mediated cytotoxicity mcc04660   T cell receptor signaling pathway mcc04662   B cell receptor signaling pathway mcc04664   Fc epsilon RI signaling pathway mcc04714   Thermogenesis mcc04720   Long-term potentiation mcc04722   Neurotrophin signaling pathway mcc04725   Cholinergic synapse mcc04726   Serotonergic synapse mcc04730   Long-term depression mcc04810   Regulation of actin cytoskeleton mcc04910   Insulin signaling pathway mcc04912   GnRH signaling pathway mcc04914   Progesterone-mediated oocyte maturation mcc04915   Estrogen signaling pathway mcc04916   Melanogenesis mcc04917   Prolactin signaling pathway mcc04919   Thyroid hormone signaling pathway mcc04921   Oxytocin signaling pathway mcc04926   Relaxin signaling pathway mcc04929   GnRH secretion mcc04933   AGE-RAGE signaling pathway in diabetic complications mcc04935   Growth hormone synthesis, secretion and action mcc04960   Aldosterone-regulated sodium reabsorption mcc05010   Alzheimer disease mcc05022   Pathways of neurodegeneration - multiple diseases mcc05034   Alcoholism mcc05160   Hepatitis C mcc05161   Hepatitis B mcc05163   Human cytomegalovirus infection mcc05165   Human papillomavirus infection mcc05166   Human T-cell leukemia virus 1 infection mcc05167   Kaposi sarcoma-associated herpesvirus infection mcc05170   Human immunodeficiency virus 1 infection mcc05200   Pathways in cancer mcc05203   Viral carcinogenesis mcc05205   Proteoglycans in cancer mcc05206   MicroRNAs in cancer mcc05207   Chemical carcinogenesis - receptor activation mcc05208   Chemical carcinogenesis - reactive oxygen species mcc05210   Colorectal cancer mcc05211   Renal cell carcinoma mcc05212   Pancreatic cancer mcc05213   Endometrial cancer mcc05214   Glioma mcc05215   Prostate cancer mcc05216   Thyroid cancer mcc05218   Melanoma mcc05219   Bladder cancer mcc05220   Chronic myeloid leukemia mcc05221   Acute myeloid leukemia mcc05223   Non-small cell lung cancer mcc05224   Breast cancer mcc05225   Hepatocellular carcinoma mcc05226   Gastric cancer mcc05230   Central carbon metabolism in cancer mcc05231   Choline metabolism in cancer mcc05235   PD-L1 expression and PD-1 checkpoint pathway in cancer mcc05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mcc00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     707977 (KRAS)    04012 ErbB signaling pathway     707977 (KRAS)    04014 Ras signaling pathway     707977 (KRAS)    04015 Rap1 signaling pathway     707977 (KRAS)    04370 VEGF signaling pathway     707977 (KRAS)    04371 Apelin signaling pathway     707977 (KRAS)    04068 FoxO signaling pathway     707977 (KRAS)    04072 Phospholipase D signaling pathway     707977 (KRAS)    04071 Sphingolipid signaling pathway     707977 (KRAS)    04151 PI3K-Akt signaling pathway     707977 (KRAS)    04150 mTOR signaling pathway     707977 (KRAS)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     707977 (KRAS)    04137 Mitophagy - animal     707977 (KRAS)   09143 Cell growth and death    04210 Apoptosis     707977 (KRAS)    04218 Cellular senescence     707977 (KRAS)   09144 Cellular community - eukaryotes    04540 Gap junction     707977 (KRAS)    04550 Signaling pathways regulating pluripotency of stem cells     707977 (KRAS)   09142 Cell motility    04810 Regulation of actin cytoskeleton     707977 (KRAS)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     707977 (KRAS)    04650 Natural killer cell mediated cytotoxicity     707977 (KRAS)    04660 T cell receptor signaling pathway     707977 (KRAS)    04662 B cell receptor signaling pathway     707977 (KRAS)    04664 Fc epsilon RI signaling pathway     707977 (KRAS)    04062 Chemokine signaling pathway     707977 (KRAS)   09152 Endocrine system    04910 Insulin signaling pathway     707977 (KRAS)    04929 GnRH secretion     707977 (KRAS)    04912 GnRH signaling pathway     707977 (KRAS)    04915 Estrogen signaling pathway     707977 (KRAS)    04914 Progesterone-mediated oocyte maturation     707977 (KRAS)    04917 Prolactin signaling pathway     707977 (KRAS)    04921 Oxytocin signaling pathway     707977 (KRAS)    04926 Relaxin signaling pathway     707977 (KRAS)    04935 Growth hormone synthesis, secretion and action     707977 (KRAS)    04919 Thyroid hormone signaling pathway     707977 (KRAS)    04916 Melanogenesis     707977 (KRAS)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     707977 (KRAS)   09156 Nervous system    04725 Cholinergic synapse     707977 (KRAS)    04726 Serotonergic synapse     707977 (KRAS)    04720 Long-term potentiation     707977 (KRAS)    04730 Long-term depression     707977 (KRAS)    04722 Neurotrophin signaling pathway     707977 (KRAS)   09158 Development and regeneration    04360 Axon guidance     707977 (KRAS)   09149 Aging    04211 Longevity regulating pathway     707977 (KRAS)    04213 Longevity regulating pathway - multiple species     707977 (KRAS)   09159 Environmental adaptation    04714 Thermogenesis     707977 (KRAS)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     707977 (KRAS)    05206 MicroRNAs in cancer     707977 (KRAS)    05205 Proteoglycans in cancer     707977 (KRAS)    05207 Chemical carcinogenesis - receptor activation     707977 (KRAS)    05208 Chemical carcinogenesis - reactive oxygen species     707977 (KRAS)    05203 Viral carcinogenesis     707977 (KRAS)    05230 Central carbon metabolism in cancer     707977 (KRAS)    05231 Choline metabolism in cancer     707977 (KRAS)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     707977 (KRAS)   09162 Cancer: specific types    05210 Colorectal cancer     707977 (KRAS)    05212 Pancreatic cancer     707977 (KRAS)    05225 Hepatocellular carcinoma     707977 (KRAS)    05226 Gastric cancer     707977 (KRAS)    05214 Glioma     707977 (KRAS)    05216 Thyroid cancer     707977 (KRAS)    05221 Acute myeloid leukemia     707977 (KRAS)    05220 Chronic myeloid leukemia     707977 (KRAS)    05218 Melanoma     707977 (KRAS)    05211 Renal cell carcinoma     707977 (KRAS)    05219 Bladder cancer     707977 (KRAS)    05215 Prostate cancer     707977 (KRAS)    05213 Endometrial cancer     707977 (KRAS)    05224 Breast cancer     707977 (KRAS)    05223 Non-small cell lung cancer     707977 (KRAS)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     707977 (KRAS)    05170 Human immunodeficiency virus 1 infection     707977 (KRAS)    05161 Hepatitis B     707977 (KRAS)    05160 Hepatitis C     707977 (KRAS)    05163 Human cytomegalovirus infection     707977 (KRAS)    05167 Kaposi sarcoma-associated herpesvirus infection     707977 (KRAS)    05165 Human papillomavirus infection     707977 (KRAS)   09164 Neurodegenerative disease    05010 Alzheimer disease     707977 (KRAS)    05022 Pathways of neurodegeneration - multiple diseases     707977 (KRAS)   09165 Substance dependence    05034 Alcoholism     707977 (KRAS)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     707977 (KRAS)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     707977 (KRAS)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     707977 (KRAS)    01522 Endocrine resistance     707977 (KRAS)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mcc04131]     707977 (KRAS)   09183 Protein families: signaling and cellular processes    04031 GTP-binding proteins [BR:mcc04031]     707977 (KRAS) Membrane trafficking [BR:mcc04131]  Endocytosis   Macropinocytosis    Ras GTPases     707977 (KRAS) GTP-binding proteins [BR:mcc04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     707977 (KRAS) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase MeaB FeoB_N ATP_bind_1 Septin G1_gp67_C TPR_Trm732 NPR1_interact Motif Other DBs NCBI-GeneID:  707977 NCBI-ProteinID:  NP_001248441 Ensembl:  ENSMMUG00000015381 UniProt:  I0FRK8 LinkDB All DBs Position 11:complement(26498849..26546682) Genome browser AA seq 188 aa AA seqDB search MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL PSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKK SKTKCVIM NT seq 567 nt NT seq  +upstreamnt  +downstreamnt atgactgaatataaacttgtggtagttggagctggtggcgtaggcaagagtgccttgacg atacagctaattcagaatcattttgtggacgaatatgatccaacaatagaggattcctac aggaagcaagtagtaattgatggagaaacctgtctcttggatattctcgacacagcaggt caagaggagtacagtgcaatgagggaccagtacatgaggactggggagggctttctttgt gtatttgccataaataatactaaatcatttgaagatattcaccattatagagaacaaatt aaaagagttaaggactctgaagatgtacctatggtcctagtaggaaataaatgtgatttg ccttctagaacagtagacacaaaacaggctcaggacttagcaagaagttacggaattcct tttattgaaacatcagcaaagacaagacagggtgttgatgatgccttctatacattagtt cgagaaattcgaaaacataaagaaaagatgagcaaagatggtaaaaagaagaaaaagaag tcaaagacaaagtgtgtaattatgtaa

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