KEGG   Macaca mulatta (rhesus monkey): 708065
Entry
708065            CDS       T01028                                 
Name
(RefSeq) cholesterol side-chain cleavage enzyme, mitochondrial
  KO
K00498  cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
Organism
mcc  Macaca mulatta (rhesus monkey)
Pathway
mcc00140  Steroid hormone biosynthesis
mcc01100  Metabolic pathways
mcc04913  Ovarian steroidogenesis
mcc04925  Aldosterone synthesis and secretion
mcc04927  Cortisol synthesis and secretion
mcc04934  Cushing syndrome
Module
mcc_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
Brite
KEGG Orthology (KO) [BR:mcc00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    708065
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    708065
   04925 Aldosterone synthesis and secretion
    708065
   04927 Cortisol synthesis and secretion
    708065
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    708065
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:mcc00199]
    708065
Enzymes [BR:mcc01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.6  cholesterol monooxygenase (side-chain-cleaving)
     708065
Cytochrome P450 [BR:mcc00199]
 Cytochrome P450, animal type
  CYP11 family
   708065
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 708065
NCBI-ProteinID: XP_014998187
UniProt: I2CWI8
LinkDB
Position
7:complement(51348476..51378582)
AA seq 521 aa
MLAKGLPPRSVLVKGCQTFLSAPKERLGHLRVPTSEGAGISTRSPRPFNEIPSPGDNGWL
NLYHFWRETGTHKVHLHHVQNFQKYGPIYREKLGNVESVYVIDPEDVALLFKSEGPNPER
FLIPPWVAYHQYYQRPIGVLLKKSAAWKKDRVALNQEVMAPETTKNFLPLLDAVSRDFVS
VLHRRIKKAGSGNFSGDISDDLFRFAFESITNVIFGERQGMLEEVVNPEAQRFIDAIYQM
FHTSVPMLNLPPDLFRLFRTKTWKDHVAAWDVIFSKADMYTENFHWELRQKGNVHHDYRG
ILYRLLGDSKMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAAR
RQAQGDMATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRGYMIPAKTLVQVAIY
ALGREPTFFFDPENFDPTRWLSKDKNITYFRNLGFGWGVRQCLGRRIAELEMTIFLINML
ENFRVEIQHLSDVGTTFNLILMPEKPISFTFWPFNQEATQE
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgctggccaagggtcttcccccacgctcagtcttggtcaaaggctgccagacctttctg
agtgcccccaaggagaggctggggcatctcagggtgcccaccagtgagggagctggcatc
tccactcgcagtcctcgccccttcaatgagatcccctctcctggtgacaatggctggcta
aacctgtaccatttctggagggagacaggcacacacaaagtccaccttcaccatgtccag
aatttccagaagtatggcccgatttacagggagaagctcggcaacgtggagtcggtttat
gtcatcgaccctgaagatgtggcccttctctttaagtccgagggccccaacccagaacga
ttcctcatcccgccctgggtcgcctatcaccaatattaccagagacccataggagtcctg
ttgaagaagtcagcagcctggaagaaagaccgggtggccctgaaccaggaggtgatggct
ccagagaccaccaagaactttttgcccctgttggatgcagtgtctcgggacttcgtcagt
gtcctgcacaggcgaatcaagaaagcaggctccggaaatttctcaggggacatcagcgat
gacctgttccgctttgcctttgagtccatcactaacgtcatttttggggagcgccagggg
atgctggaggaagtagtgaaccccgaggcccagcggttcattgatgccatctaccagatg
ttccacaccagcgtccccatgctcaaccttcccccagacctattccgtctgttcaggacc
aagacctggaaggaccatgtggccgcatgggacgtgattttcagcaaagctgacatgtac
accgagaacttccactgggaattgagacagaaaggaaatgttcaccatgattaccgtggc
atcctctacagactcctgggagacagcaagatgtccttcgaggacatcaaggccaacgtc
acagagatgctggcaggaggggtggacacgacgtccatgaccctgcagtggcacttgtat
gagatggcacgcaacctgaaggtgcaggatatgctgcgggcagaggtcttggctgcgcgg
cgccaggcccagggagacatggccacgatgctgcagctggtccccctcctcaaagccagc
atcaaggagacactgagacttcaccccatctccgtgaccctgcagagatatctcgtaaat
gacttggttcttcgaggttacatgattcctgccaagacactggtgcaggtggccatctat
gctctgggccgagagcccactttcttcttcgacccggaaaattttgacccaacccgatgg
ctgagcaaagacaagaacattacctacttccggaacttgggctttggctggggtgtgcgg
cagtgtctgggacggcggatcgccgagctagagatgaccatcttcctcatcaatatgctg
gagaacttcagagttgaaatccaacatctcagcgatgtgggcaccacattcaacctcatc
ctgatgcctgaaaagcccatctccttcaccttctggccctttaaccaggaagcaacccag
gagtga

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