Macaca mulatta (rhesus monkey): 708706
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Entry
708706 CDS
T01028
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc04010
MAPK signaling pathway
mcc04020
Calcium signaling pathway
mcc04022
cGMP-PKG signaling pathway
mcc04024
cAMP signaling pathway
mcc04260
Cardiac muscle contraction
mcc04261
Adrenergic signaling in cardiomyocytes
mcc04270
Vascular smooth muscle contraction
mcc04723
Retrograde endocannabinoid signaling
mcc04725
Cholinergic synapse
mcc04726
Serotonergic synapse
mcc04727
GABAergic synapse
mcc04911
Insulin secretion
mcc04912
GnRH signaling pathway
mcc04921
Oxytocin signaling pathway
mcc04924
Renin secretion
mcc04925
Aldosterone synthesis and secretion
mcc04927
Cortisol synthesis and secretion
mcc04929
GnRH secretion
mcc04934
Cushing syndrome
mcc04935
Growth hormone synthesis, secretion and action
mcc05010
Alzheimer disease
mcc05020
Prion disease
mcc05022
Pathways of neurodegeneration - multiple diseases
mcc05207
Chemical carcinogenesis - receptor activation
mcc05410
Hypertrophic cardiomyopathy
mcc05412
Arrhythmogenic right ventricular cardiomyopathy
mcc05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
708706 (CACNA1S)
04020 Calcium signaling pathway
708706 (CACNA1S)
04024 cAMP signaling pathway
708706 (CACNA1S)
04022 cGMP-PKG signaling pathway
708706 (CACNA1S)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
708706 (CACNA1S)
04929 GnRH secretion
708706 (CACNA1S)
04912 GnRH signaling pathway
708706 (CACNA1S)
04921 Oxytocin signaling pathway
708706 (CACNA1S)
04935 Growth hormone synthesis, secretion and action
708706 (CACNA1S)
04924 Renin secretion
708706 (CACNA1S)
04925 Aldosterone synthesis and secretion
708706 (CACNA1S)
04927 Cortisol synthesis and secretion
708706 (CACNA1S)
09153 Circulatory system
04260 Cardiac muscle contraction
708706 (CACNA1S)
04261 Adrenergic signaling in cardiomyocytes
708706 (CACNA1S)
04270 Vascular smooth muscle contraction
708706 (CACNA1S)
09156 Nervous system
04727 GABAergic synapse
708706 (CACNA1S)
04725 Cholinergic synapse
708706 (CACNA1S)
04726 Serotonergic synapse
708706 (CACNA1S)
04723 Retrograde endocannabinoid signaling
708706 (CACNA1S)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
708706 (CACNA1S)
09164 Neurodegenerative disease
05010 Alzheimer disease
708706 (CACNA1S)
05020 Prion disease
708706 (CACNA1S)
05022 Pathways of neurodegeneration - multiple diseases
708706 (CACNA1S)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
708706 (CACNA1S)
05412 Arrhythmogenic right ventricular cardiomyopathy
708706 (CACNA1S)
05414 Dilated cardiomyopathy
708706 (CACNA1S)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
708706 (CACNA1S)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
mcc04040
]
708706 (CACNA1S)
Ion channels [BR:
mcc04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
708706 (CACNA1S)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
PKD_channel
Motif
Other DBs
NCBI-GeneID:
708706
NCBI-ProteinID:
XP_014975975
Ensembl:
ENSMMUG00000017414
UniProt:
F7HPW3
LinkDB
All DBs
Position
1:complement(58468289..58543090)
Genome browser
AA seq
1873 aa
AA seq
DB search
MEPSSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLENPLRKACISIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNSLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFTIVFLGVFTVILEQVNVIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFTGTDIVATVENE
EPSPCARTGSGRRCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLD
EDLRGYMSWITQGEVMDVEDFREGKLSLDEGGSDTESLYEIAGLNKIIQFIRHWRQWNRI
FRWKCHDIVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTRLQDIANRVLLSLFTVEML
MKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLLRIFKITK
YWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRYDFEDTEVRRSNFDNF
PQALISVFQVLTGEDWTSMMYNGIMAYGGPSYPGMLVCIYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEERKRRKMSKGLPDKSEEEKSTMAKKLEQKPKGEGIPTTAKL
KIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPLSPRPRPLAELQLKEKAVPIPEASSFF
IFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILKHFDIGFT
SVFTVEIVLKMTTYGAFLHKGSFCRNYFNMLDLLVVAVSLISMGLESSAISVVKILRVLR
VLRPLRAINRAKGLKHVVQCMFVAISTIGNIVLVTTLLQFMFACIGVQLFKGKFFRCTDL
SKMTEEECRGYYYVYKDGDPMQIELRHREWVHSDFHFDNVLSAMMSLFTVSTFEGWPQLL
YKAIDSNEEDVGPIYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHY
NQSEQMNHISDILNVAFTIIFTLEMILKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIALVDGTQINRNNNFQTFPQAVLLLFRCA
TGEAWQEILLACSYGKLCDPESDYAPGEEYTCGTNFAYYYFISFYMLCAFLVINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDIVQIQAGLR
TIEEEAAPEIRRTVSGDLAAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNSLPP
VMASQRPLQFTEIEMEELESPVFLEDFHQDPRTNPLARANTNNANANVAYGNSNHSNSHV
FSSVHYEREFPEETETSAIRGGALGQPCRALGPHSKPCVEKLKGLMTQRAMPRGQAPPAP
CQCPRVESPMPEDRRSSTPGSLHEETPHSRSTGENTSRCSAPATTLLIQEALVRGGLGTL
AADANFIMATGQALADACQMEPEEVEVMATELLKGREAPEGMASSLGCLNLGSSLGSLDQ
HQGSQETLIPPRL
NT seq
5622 nt
NT seq
+upstream
nt +downstream
nt
atggagccgtcctcaccccaggatgaaggcctgaggaagaaacagcccaagaagccggtt
cctgagattctgccaaggccaccccgggccttgttctgcctgaccctggagaaccccctg
aggaaggcctgcatcagcatcgtagaatggaagcccttcgagacgatcatcttgcttacc
atctttgccaactgtgtggccttggccgtgtacctgcccatgccagaagatgacaacaac
tctctgaacctcggcctggagaagctggagtatttcttcctcatcgtcttctcgattgaa
gccgccatgaagatcattgcctacggcttcttattccaccaggatgcttacctgcgcagc
ggctggaatgtgctggacttcaccattgtcttcctgggggtcttcaccgtgattctggaa
caggttaacgtcatccaaagcaacacagccccaatgagcagcaaaggagccggcttggat
gtcaaggccctcagagccttccgagtgctcagacccctccggctggtgtcgggggtgcct
agcctgcaggtggtcctgaactccatcttcaaggccatgctccccctcttccacatcgcc
ctgctggtcctctttatggtcatcatctatgccatcatcgggctggagctcttcaagggc
aagatgcacaagacctgctacttcactggcacagatatcgtggccacagtggagaatgag
gagccatcgccctgtgccaggacaggctcagggcgccggtgcaccatcaatggcagtgag
tgccggggtggctggccagggcccaaccatggcatcacccactttgacaacttcggcttc
tccatgctcaccgtgtaccagtgcatcaccatggagggatggactgacgtcctttactgg
gtcaatgatgccatcgggaatgagtggccctggatctattttgtcaccctcattctgctg
ggatccttcttcatcctcaacctggtgctgggtgtcctgagcggggaattcaccaaggag
cgggagaaggccaagtccaggggaaccttccagaagctccgggagaagcagcagctagat
gaggaccttcggggctacatgagctggatcacgcagggcgaggtcatggacgttgaggac
ttcagagaaggaaaactgtctttggatgaaggtggctctgacacagagagcctgtatgaa
attgcaggcttgaacaaaatcatccagttcatccggcactggaggcagtggaaccgcatc
tttcgctggaagtgccacgacatcgtgaagtccaaggtcttctattggctagtgattctc
atcgttgccctcaacaccctgtctatcgcctcagagcaccacaaccagcctctctggctg
acccgtttacaagacattgccaaccgggtgctactgtccctcttcactgtcgagatgctg
atgaagatgtatgggctgggcctgcgccagtacttcatgtccatcttcaaccgcttcgac
tgcttcgtggtgtgcagcggcatcctggagatcctgctggtggagtcgggcgccatgacg
cccctgggcatctccgtgctccgctgcatccgcctcctgaggatcttcaagatcaccaaa
tactggacgtcgctgagcaacctggtggcatccctgctcaactccatccgctccatcgcc
tccctgctgctgctgctcttcctcttcatcgtcatcttcgccctcctgggcatgcagctc
tttggggggaggtatgactttgaggacacagaagtacggcgcagcaacttcgacaacttt
ccccaagccctcatcagcgtcttccaggtcctgacgggtgaagactggacttcaatgatg
tacaatgggatcatggcctacggtgggccgtcctaccccggcatgcttgtgtgcatttac
ttcatcatcctttttgtctgtggcaactacatcctgctcaatgtcttcctggccattgcc
gtggacaacctggccgaggcggagagcctgacttctgcccagaaagccaaggctgaggaa
agaaaacgcaggaagatgtccaagggtctcccagacaagtcagaggaggagaagtccacg
atggccaagaagctggagcagaaacccaagggtgaaggcatccccaccactgccaagctg
aaaattgatgagtttgaatctaatgtcaatgaggtgaaggatccctatccctcagctgac
ttcccaggggatgacgaggaagatgagcccgagatcccactgagcccccgtccacgcccc
ctggctgagctgcagctgaaagagaaggccgtgcccattccagaagccagttccttcttc
attttcagccccaccaataagatccgtgtcctgtgtcaccgcatcgtcaatgccacctgg
ttcaccaacttcatcctgctctttatcctgctcagcagcgctgcactggctgcggaagac
cccatccgggctgattccatgaggaatcagatccttaaacactttgacatcgggttcacc
tctgtcttcactgtggagattgtcctcaagatgacgacctatggagccttcctgcacaaa
ggttccttctgccgcaattacttcaacatgctggacctgctggtggtggccgtgtccctc
atctccatgggacttgagtccagcgccatctccgtggtgaagatcctgagggttctgagg
gtgctccgaccactcagagccatcaacagagccaaggggttgaagcacgtggtgcagtgc
atgttcgtggccatcagcaccatcgggaacatcgtgctggtcactaccctcctacagttc
atgtttgcctgcatcggcgtccagctcttcaaggggaagttcttcaggtgcaccgacttg
tccaagatgacagaggaggagtgcaggggctactactacgtgtacaaggacggggacccc
atgcagatagagctgcgtcaccgtgagtgggtacacagcgacttccacttcgacaatgtg
ctctcagccatgatgtccctcttcacggtctccaccttcgagggatggcctcaactgctg
tacaaggccatagactccaatgaggaggatgtgggtcccatctacaacaaccgtgtggag
atggccatcttcttcatcatctacatcatcctcattgctttcttcatgatgaacatcttc
gtgggcttcgtcattgtcaccttccaggagcagggagagactgagtacaagaactgtgag
ctggacaagaaccagcgccaatgtgtacagtacgccctgaaggcccgcccactgaggtgc
tacattcccaaaaacccataccagtaccaggtgtggtacgttgtcacctcctcctacttt
gaatacctgatgtttgcccttatcatgctcaacaccatctgccttggcatgcagcactac
aaccagtcagagcagatgaaccacatttcagacatcctcaatgtggccttcactatcatc
ttcaccctggagatgatccttaagctcatggccttcaaggccaggggttactttggagac
ccctggaatgtgtttgacttcctgattgtcattggcagcatcattgatgtcatcctcagc
gagatcgacactttcctggcctccagcgggggactgtattgcctgggtggaggctgcggg
aacgttgacccagatgagagtgcccgcatctccagtgccttcttccgcctgttccgtgtc
atgaggctgatcaagctgctgagccgggcagagggagtgcgcaccctcctgtggacgttc
atcaagtccttccaggccctaccctacgtggctctgctcatcgtcatgctcttcttcatc
tacgctgtcatcggcatgcagatgtttgggaagatcgccttggtggatgggacccaaata
aaccggaacaacaacttccagaccttcccacaagctgtgctgctgctcttcaggtgtgca
acaggtgaggcctggcaggaaatcctactggcctgcagctatgggaagctgtgtgaccca
gagtcggactacgccccaggggaggagtacacatgtggcaccaactttgcatactactac
ttcatcagcttctacatgctctgcgccttcctggtcatcaacctctttgtggctgtcatc
atggacaattttgactacctcacccgggactggtccatcctgggccctcatcacctggat
gagttcaaggccatctgggcagagtatgacccggaggctaaggggaggatcaaacacctg
gacgtggtgaccctgctgagaaggattcagccccctctgggctttgggaagttctgccca
catcgcgtagcttgtaagcggctggtgggcatgaacatgcccctgaacagtgacggcaca
gtcaccttcaatgccacactcttcgccctggtccgcacagcacttaagatcaagacagaa
ggtaactttgagcaggccaatgaggagctgagggccatcatcaagaagatctggaagaga
accagcatgaagctcttggaccaggtcatccctccaataggagatgatgaggtgacagtg
gggaagttctacgccacattcctcatccaggagcacttccggaagttcatgaagcgccag
gaggagtattatggctatcggcccaagaaggacattgtacagatccaggcaggactgcgg
accattgaggaagaggcagcccccgagatccgtcgcacggtctcaggagacctggctgct
gaggaggagctggagagagccatggtggaggctgcaatggaggagggaatattccggagg
actggaggcctgtttggccaggtggacaacttcctggaaaggaccaactccctgcccccg
gtcatggccagtcagaggcccctccagtttactgagatagagatggaagagctggagtca
ccggtcttcttggaggacttccatcaagatccacgcaccaaccccctggctcgtgccaat
accaacaatgccaatgccaatgttgcctatggcaacagcaaccatagcaacagtcatgtg
ttttccagtgtccactatgaaagggagttcccagaagagacagagacatctgctatcaga
ggaggagcccttggccaaccctgcagggccctgggaccccacagcaaaccttgtgtggag
aagctaaagggactgatgacccagagggcaatgcccagaggccaggcacctcctgccccc
tgccagtgccccagggtggagtcccccatgcctgaggacagaaggagctccacaccaggg
tctctgcacgaggagacaccccacagcaggagcaccggggagaatacttccaggtgctca
gcgccagctacaaccctgctgatccaagaggctctggttcgagggggcctgggcaccttg
gcagctgatgcaaacttcatcatggcaacaggccaggccctggcagatgcctgccaaatg
gaaccagaggaagtggaggtcatggcaacagagctactgaaaggacgagaggccccagag
ggcatggctagctccctgggatgcctgaacctcggttcctccctgggcagccttgaccag
caccagggctcccaggagacccttattcctcccaggctgtga
DBGET
integrated database retrieval system
