Macaca mulatta (rhesus monkey): 710019
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Entry
710019 CDS
T01028
Symbol
IDH1
Name
(RefSeq) isocitrate dehydrogenase [NADP] cytoplasmic
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc00020
Citrate cycle (TCA cycle)
mcc00480
Glutathione metabolism
mcc01100
Metabolic pathways
mcc01200
Carbon metabolism
mcc01210
2-Oxocarboxylic acid metabolism
mcc01230
Biosynthesis of amino acids
mcc04146
Peroxisome
mcc05230
Central carbon metabolism in cancer
Module
mcc_M00009
Citrate cycle (TCA cycle, Krebs cycle)
mcc_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
710019 (IDH1)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
710019 (IDH1)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
710019 (IDH1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
710019 (IDH1)
Enzymes [BR:
mcc01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
710019 (IDH1)
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GFIT
Motif
Pfam:
Iso_dh
XRN1_D2_D3
Motif
Other DBs
NCBI-GeneID:
710019
NCBI-ProteinID:
NP_001252708
Ensembl:
ENSMMUG00000016077
UniProt:
I2CTQ9
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Position
12:complement(95649267..95667830)
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AA seq
414 aa
AA seq
DB search
MSKKISGGSVVELQGDEMTRIIWELIKEKLIFPYVELDLQSYDLGIENRDATNDQVTKDA
AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKSQFE
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELAFFANALE
EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
NT seq
1245 nt
NT seq
+upstream
nt +downstream
nt
atgtccaaaaaaatcagtggcggttctgtggtagagctgcaaggagatgaaatgacacga
atcatttgggaattgattaaagagaaactcatttttccctatgtggaattggatctacag
agctatgatttaggcatagagaatcgtgatgccaccaacgaccaggtcaccaaggatgct
gcagaagctataaagaagtataatgttggcgtcaaatgtgccactatcactcctgatgag
aagagggttgaggagttcaagttgaaacaaatgtggaaatcaccaaatggcaccatacga
aatattctgggtggcacggtcttcagagaagccattatctgcaaaaatatcccccggctt
gtgagtggatgggtaaaacctatcatcataggtcgtcatgcttacggggatcaatacaga
gcaactgattttgttgttcctgggcctggaaaagtagagataacctacacaccaagtgat
ggaacccaaaaggtgacatacctggtacataactttgaagagggtggtggtgttgccatg
gggatgtataatcaagataagtcaattgaagattttgcacacagttccttccaaatggct
ctgtctaagggttggcctttgtatctgagcaccaaaaacactattctgaagaaatatgat
gggcgttttaaagacatctttcaggagatatatgacaagcagtacaagtcccaatttgaa
gcccaaaagatctggtatgagcataggctcatcgatgacatggtggcccaagctatgaaa
tcagagggaggcttcatctgggcctgtaaaaactatgatggtgacgtgcagtcggactct
gtggcccaagggtatggctctctcggcatgatgaccagtgtgctggtttgtccagatggc
aagacagtagaagcagaggctgcccacgggactgtaacccgtcactaccgcatgtaccag
aaaggacaggagacgtccaccaatcccattgcttccatttttgcctggaccagagggtta
gcccacagagcaaagcttgataacaataaagaacttgccttctttgcaaatgctttggaa
gaagtctgtattgagacaattgaggctggcttcatgaccaaggacttggccgcttgcatt
aaaggtttacccaatgtgcaacgttctgactacttgaatacatttgagttcatggacaaa
cttggagaaaacttgaagatcaaactagctcaggccaaactttaa
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