Macaca mulatta (rhesus monkey): 710833
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Entry
710833 CDS
T01028
Symbol
HMGCL
Name
(RefSeq) hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X2
KO
K01640
hydroxymethylglutaryl-CoA lyase [EC:
4.1.3.4
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc00280
Valine, leucine and isoleucine degradation
mcc00650
Butanoate metabolism
mcc01100
Metabolic pathways
mcc04146
Peroxisome
Module
mcc_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
710833 (HMGCL)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
710833 (HMGCL)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
710833 (HMGCL)
Enzymes [BR:
mcc01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.3 Oxo-acid-lyases
4.1.3.4 hydroxymethylglutaryl-CoA lyase
710833 (HMGCL)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
Aldolase_II
Motif
Other DBs
NCBI-GeneID:
710833
NCBI-ProteinID:
XP_014986375
Ensembl:
ENSMMUG00000019548
UniProt:
H9Z8B6
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Position
1:200922420..200964472
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AA seq
325 aa
AA seq
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MAAMTKALPRRLVGLASLRAVSTSSMDTLPKQVKIVEVGPRDGLQNEKNIVSTPVKIKLI
DMLSEAGLSVIEATSFVSPKWVPQMADHAEVLKGIQKFPGITYPVLIPNLKGFEAAVAAG
AKEVSIFGAASELFTKKNINCSIEESFQRFDAILKAAQSANISVRGYVSCVLGCPYEGKI
SPAKVAEVTKKFYSMGCYEISLGDTIGVGTPGIMKDMLSAVMQEVPPAALAVHCHDTYGQ
ALANTLMALQMGVSVVDSSVAGLGGCPYAQGASGNLATEDLVYMLEGLGIHTGVNLQKLL
EAGNFICQALNRKTSSKVAQATCKL
NT seq
978 nt
NT seq
+upstream
nt +downstream
nt
atggcagcaatgacgaaggcgcttccgcggcgactggtgggcttggcgtcccttcgggct
gtcagcacctcatctatggacactttaccaaagcaagtgaaaattgtggaagttggtccc
cgagacggtctacaaaatgaaaagaatatcgtatctactccagtgaaaatcaagctgata
gacatgctttctgaagcaggactctctgttatagaagcaaccagctttgtgtctcctaag
tgggttccccagatggctgaccatgctgaagtcttgaagggcattcagaagtttcctggc
atcacctacccagtcctgatccccaatttgaaaggcttcgaggcagcggttgctgctgga
gccaaggaagtcagcatctttggagctgcctcagagcttttcaccaagaagaacatcaat
tgttccatagaggagagttttcagaggtttgacgcgatcttgaaggcagcacaatcagcc
aatatttctgtgcgggggtacgtctcctgtgtgcttggctgcccttatgaagggaagatc
tccccagctaaagtagctgaggtcaccaagaagttctactcaatgggctgctacgagatc
tccctgggggacaccattggtgtgggcaccccagggatcatgaaagacatgctgtctgct
gtcatgcaggaagtgcctccggctgccctggctgtccactgccatgacacctatggccaa
gccctggccaacaccctgatggccctgcagatgggagtgagtgtcgtggactcttctgtg
gcaggacttggaggctgtccctatgcacagggggcatcaggaaacttggccacggaggac
ctggtctacatgctagagggcttgggcattcacacgggtgtgaatctccagaagcttctg
gaagctgggaactttatctgtcaagccctgaacagaaaaactagctccaaagtggctcag
gctacctgtaaactctga
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