Macaca mulatta (rhesus monkey): 711782 Help Entry 711782            CDS       T01028                                  Symbol SYNE1 Name (RefSeq) nesprin-1 isoform X1   KO K19326   nesprin-1 Organism mcc  Macaca mulatta (rhesus monkey) Pathway mcc04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:mcc00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     711782 (SYNE1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:mcc03036]     711782 (SYNE1) Chromosome and associated proteins [BR:mcc03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     711782 (SYNE1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 SYNE1 CH KASH Spectrin_SYNE1_2 SYNE3 STIV_B116-like Motif Other DBs NCBI-GeneID:  711782 NCBI-ProteinID:  XP_028703074 Ensembl:  ENSMMUG00000019048 LinkDB All DBs Position 4:complement(58291310..58820670) Genome browser AA seq 8832 aa AA seqDB search MATSRGASRCPRDIANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDG VKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKSMHRGSPIKLVNINSTD IADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVT TKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLEKVKGR SNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNAGTDGQ EDDEILPGFPSFANSIQNFKREDRLILKEMKVWIEQFERDLTRAQMVESNLQDKYQSFKH FRVQYEMKRKQIEHLVQPLHRDGKLSLDQALVKQSWDRVTSRLFDWHIQLDKSLPAPLGT IGAWLYRAEVALREEITIQQVHEETANTIQRKLEQHKDLLQNTDAHKRAFHEIYRTRSVN GIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRR ESVEQLLQNYVSFIENSKFFEQYEVTYQILKQTAEMYVKAEGSVEEAENVMKFMNETTAQ WRNLSVEVRSVRSMLEEVISNWDRYGNTVASLQAWLEDAEKMLNQSEIAKKDFFRNLPHW IQQHTAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYAQADEMDRMKKEY TDCVFTLSAFATEAHKKFCEPLEVSFMNVKLLIQDLEDIEQRVPVMDAQYKIITKTAHLI TKESPQEEGKEMFATMSKLKEQLTKVKECYSPLLYESQQLLIPLEELEKQMTSFYDSLGK INEIITVLEREAQSSALFKQKHQELLACQENCKKTLTLIEKGSQSVQKFVTLSNVLKHFD QTRLQRQIADVHVAFQSMVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEK GDPEELLRRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQG EAPYHLLHLKIDVEKNRFLASVEECRTELDRETKLMPQEGSEKIIKEHRVFFSDKGPHHL CEKRLQLIEELCVKLPVRDPVRDTPGTCHATLKELRAAIDSTYRKLMEDPDKWKDYTNRF SEFSSWISTNETQLKGIKGEAIDTANHREVKRAVEEIRNGVTKRGETLSWLKSRLKVLTE VSSENQAQKQGDELAKLSSSFKALVTLLSEVEKMVSNFGDCVQYKEIVKNSLEELISGSK EVQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIAQAQQEEGGLPDRGREE LRKLESTLDGLERSRERQERRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSFSSLE SLSSELEQTKEFSKRTENIAVQAENLVKEASEIPLGPQNKQLLQQQAQSIKEQVKKLEDT LEEDIKTMEMVKTKWDHFGSNFETLSVWITEKEKELNALETSSSAMDMQISQIKVTIQEI ESKLSSIVGLEEEAQSFAQFVTTGESARIKAKLTQIRRYWEELREHAQCLEGTILGHLSQ QQKFEKNLRKIQQSVSEFEDKLAVPIKICSSATETYKVLQEHMDLCQALESLSSLITTFS ASARKVVNRDSCVQEAAALQHQYEDTLRRAKERQTALENLLAHWQRLEKELSSFLTWLER GEAIASSPEMDISADRVKVEGELQLIQALQNEVVSQASFYSKLLQLKESLFSIASKDDVK MVKLHLEQLDERWRDLPQIIDKRINFLQSVVAEHQQFDELLLSFSVWIKLFLSELQTTSE ISIMDHQVALTRHKDHAAEVESKKVELQSLQGHLAKLGSLGRAEDLHLLQGKAEDCFQLF EEASQVVERRQLALSHLAEFLQSHASLSGILHQLRQTVEATNSMNKNESDLIEKDLNDAL QDAKALESAAVSLDGILSKAQYHLKSGSSEQRTSCRATADQLCGEVERIQNLLGTKQSEA DALAVLKKAFQDQKEELLKSIEDIEERTDKERLKEPTRQALQQRLRVFNQLEDELNSHEH ELCWLKDKAKQIAQKDVAFAPEVDREINRLAVTWDDTKRLIHENQGQCCGLIDLMREYQN LKSTVSKVLENASSVIVTRTTIKDQEDLKWAFSKHETAKNKMNYKQKDLDNFTSKGKHLL SELKKIHSSDFSLVKTDMESTVDKWLDVAEKLEENMDRLRVSLSIWDDVLSSRDEIEGWS NNSVPQMAKNISNLDNRLRAEELLKEFESEVKNKALRLEELHSKVNDLKELTKNLETPPD LQFIEADLRQKLEHAKEITEVAKGTLKDFTAQSTQVEKFINDITTWLAKVEESLMNCAQT DTCEGLKKVKDIQKELQSQQSNISSTQENLNSLCRKYHSAELENLGCAMTGLIKKHEVVS QLCSKTQASLQESLEKHFSESMQEFQEWFLGAKASAKESSDRTGDSKVLEAKLHDLQNLL DSVSDGQSKLDAVTQEGQTLYAHLSKQIVSSIQEQITRANEEFQAFLKQCLKDKQALQDC ASELGSFEDQHRKLNLWIHEMEERFNTENLGESKQHIPEKKNEVHKVEMFLGELLAARES LDKLSQRGQLLSEEGHGAGQEGRLCSQLLTSHQNLLRMTKEKLRSCQVALQEHEALEEAL QSMWSWVKAIQDRLACAESTLGSKDTLEKRLSQIQDILLMKGEGEVKLNMAIGKGEQALR SSNKEGQRVIQTQLETLKEVWADIMSSSIHAQSTLESVISQWNDYLERKNQLEQWMESVD QKVEHPLQPQPGLKEKFALLDRLQSILSEAEDHTRALHRLIAKSRELYEKTEDESFKDTA QEELKTQFNDIMTVAKEKMRKVEEIVKDHLMYLDAVHEFTDWLHSAKEELHRWSDMSGDS SATQKKLSKIKELIDSREIGASRLSRVESLAPEVKQNTTASGCELMHTEMQALRADWKQW EDSVFQTQSCLENLVSQMALSEQEFSGQAAQLEQALQEFSALLKTWAQQLTLLEGKNTDE EIVECWHKGQEILDALQKAEPRTEDLKSQLNELCRFSRDLSTYSGKVSGLIKEYNCLCLQ ASKGCQNKEQILQQRFRKAFRDFQQWLVNAKITTAKCFDIPQNISEVSTSLQKIQEFLSE SENGQHKLNVMLSKGELLSTLLTKEKAKGIQAKVSGAKEDWKNFHSNLHQKESALENLKI QMKDFEVSAEPIQDWLSKTEKMVHESSNRLYDLPAKRREQQKLQSVLEEIHCYEPQLNRL KEKAQQLWEGQAASKSFRHRVSQLSSQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKELQ DWMTDAIHMLDSYCHPTSDKSVLDSRTLKLEALLSVKQEKEIQMKMIVTRGESVLQNTSP EGIPTIQQQLQSVKDMWASLLSAGIRCKSQLEGALSKWTSYQDDVRQFSGWMDSMEANLN ESERQHAELRDKISMLGKAKLLNEEVLSYSSLLETIEVKGAGMTEHYVTQLELQDLQERY RAIQERAKEAVTKSEKLVRLHQEYQRDLKAFEVWLGQEQEKLDQYSVLEGDAHTHETTLR DLQELQVHCAEGQALLNSVLHTREDVIPSGIPQAEDRALESLRQDWQVYQHKLSETRTQF NNVVNKLRLMEQKFQQVDEWLKTAEEKISPRTIRQSNRATKEIQLHQMKKWHEEVTAYRD EVEEVGARAQEILDESHVNSRMGCQATQLTSRYQALLLQVLEQIKFLEEEIQSLEESESS LSSYSDWYGSTHKNFKNVATKIDKVDTTMMGKKLKTLEVLLKDMEKGHSLLKSAREKGER AVKYLEEGEAERLRKEIHDHVEQLKELTSTVRKEHMTLEKGLHLAKEFSDKCKALTQWIA EYQEILRVPEEPKMELYEKKAQLSKYKSLQQTVLSHEPSVKSVREKGEALLELVQDVTLK DKIDQLQSDYQDLCSIGKEHVFSLEAKVKDHEDYNSELQEVEKWLLQMSGRLVAPDLLET SSLETITQQLAHHKAMMEEIAGFEDRLNNLQMKGDTLIGQCADHLQAKLKQNVHAHLQGT KDSYSAICSTAQRVYQSLEHELQKHVSRQDTLQQCQAWLSTVQPDLEPSPQPPLSRAEAV KQVKHFRALQEQARTYLDLLCSMCDLSNASVKTTAKDIQLTEQMIEQRLVQAQNLTQGWE EIKHLKAELWIYLQDADQQLQNMKRRHSELELSIAQNMVSQVKDFVKKLQSKEASVNTII EKVNKLTKKEESPEHKEINHLNDQWLDLCHQSNNLCLQREEDLQRTRDYHDCMNVVEVFL EKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNLDDKEL VKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMDWAEEQQPNIAEALKQ SPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALSDAQSH VNCLSDLVGQRRKYLNKALSEKSQFLMAVFQATSQIQQHERKIMFREHICLLPDDVSKQV KTCKSAQASLKTYQNEVTGLWAQGRELMKGVTEQEKSEVLGKLQELQSVYDSVLQKCSHR LQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESTELHTQLAKYQHILEQSP EYENLLLMLQRTGQTILPSLNEVDHSYLSEKLNTLPQQFNVIVALAKDKFYKVQEAILAR KEYASLIELTTQSLSELEAQFSRMSKVPTDLAVEEAVALQDGCRAILDEVVGLGEAVDEL NQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQQLERQ LKSVKEEQSKVNEETLPAEEKLKMYHSLGGSLQDSAILLKRVTIHLEDLAPHLDPLAYEK ARHQIQSWQEELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELSGPVYL DLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLAELSEL DGDIQEALRTRQATLTEMFSQCQRYYQVFQAANDWLEDAQEMLQLAGNGLDVESAEENLK NHMEFFSTEDQFHSNLEELRGLVATLDPLIKPTGKEDLEQKMASLELRSQRMSQDSCAQV DLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSDEAEEKLSEHKALVSVVN SFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILEDAVDEW TGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSALGMLRQ QALSMLQDGAAPTPGGEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMVETQIN SVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKDKYLGLYTILP SELSLQLAEVALDLKIRDQIQDKIKEVEQSKAMSQELSRQIQKIAKDLTTILTKLKAKTD NLVQAKTDQKVLGEELDGCNSKLMELDAAVQKFSEQNGQLGKPLAKKIGKLTELHQQTIR QAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIPWNSASQLREQYILHQTLL EESKEIHSDLEVMTEKLQYLTSVYCTEKMSQQVAELGRETEELQQMIKIRLQNLQDAAKD MKKFEAELKKLQTALEQAQATLTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVQAVQLCQ SALRIPEDVVASLPLCHAALRLQEEASRLQHTAIQQCNIMQEAVVQYEQYEQEMKHLQQL IEGAHREIEDKPVATSNIQELQAQISRHEELAQKIKGYQEQIASLNSKCKMLTMKAKHAT MLLTVTEVEGLAEGTEDLDGELLPAPSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEI SSPPACRSPSPVANTDASVNQDIAYYQALSAERLQTDAAKIHPSTSASQELYEPGLEPSA TAKLGDLQRSWETLKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAIELKLSESPEPG RSPESQMAEHQSFLQALMDEILMLQDEINELQSSLAEELVSKSCEADPAEQLALQSTLTV LAERMSTIRMKASGKRQLLEEKLNDQLEEQRQEQALQRYRCEADELDSWLLSTKATLDTA LGTPKEPMDMEAQLVDCQNMLVEIEQKVVALSELSVHNENLLLEGKAHTKDEAEQLAGKL RRLKGSLLELQRALHDKQLNMQQGTAQEKEESDVDLTATQSPGVQEWLAQARTTWTHQRQ SSLQQQKELEQELAEQKSLLRSVASRGEEILIQHSAAETSGDAGEKPDVLSQELGMEGEK SSAEDQMRMKWESLHQEFSTKQKLLQNVLEQEQEQVLYSRPNRLLSGVPLYKGDVPIQDK SAVTSLLDGLNQAFEEVSSQSGGTKRQSIHLEQKLYDGVSATSTWLDDVEERLFVATALL PEETETCLFNQEILAKDIKEMSEEMDKNKNLFSQAFPENGDNRDVIEDTLGCLLGRLSLL DSVVNQRCHQMKERLQQILNFQNDLKVLFTSLADNKYIILQKLANVFEQPVAEQIEAIQQ AEDGLKELDAGIIELKRRGDKLQIEQPSMQELSKLQDMYDELMMTIGSRRSGLNQNLTLK SQYERALQDLADLLETGQEKMAGDQKIIVSSKEEIQQLLDKHKEYFQGLESHMILTETLF RKIISFAVQKETQFHTELMAQASAVLKRAHKRGVELEYILETWSHLDEDQQELSRQLEVV ENSIPSVGLVEENEDRLIDRITLYQHLKSSLNEYQPKLYQVLDDGKRLLISISCSDLESQ LNQLGERWLSNTNKVSKELHRLETILKHWTRYQSESADLIHWLQSAKDRLEFWTQQSVTV PQELEMVRDHLNAFLEFSKEVDAKSSLKSSVLSTGNQLLRLKKVDTATLRSELSHIDSQW TDLLTNIPAVQEKLHQLQMDKLPSRHAISEVMSWISLMENVIQKDEDNIKNSIGYKAIHE YLQKYKGFKIDINCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQILQG LVTEKIQLLEGLLESWSEYENNVQCLKTWFETQEKRLKQQHRIGDQASVQNALKDCQDLE DLIKAKEKEVEKIEQNGLALIQNKKEDVSGIVVGTLQGLGQTWASLDHMVGQLKILLKSV LDQWSNHKVAFDKINSYLMEARYSLSRFRLLTGSLEAVQVQVDNLQNLQDDLEKQERSLQ KFGSITNQLLKECHPPVTETLTNTLKEVNMRWNNLLEEIAEQLHSSKALLQLWQRYKDYS KQCASSVQQQEDRTNELLKAATNKDIADDEVATWIQDCNDLLKGLGTVKDSLFVLHELGE QLKQQVDASAASALQSDQLSLSQHLCALEQALCKQQTSLQAGVLDYETFAKSLEALEAWI VEAEEILQGQDPSHSSDLSTIQERMEELKGQMLKFSSMAPDLDRLNELGYRLPLNDKEIK RMQNLNRHWSLISSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQ HLLEQQRAHELFQAEMFSRQQILHSIIIDGQRLLEQGQVDDRDEFNLKLTLLSNQWQGVI RRAQQRRGIIDSQIRQWQRYREMAEKLRKWLVEVSYLPMSGLGSVPIPLQQARTLFDEVQ FKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELTEIQEKWKSASVRLEEQKKKL AFLLKDWEKCEKGIADSLEKLRTFKKKLSQCLPDHHEELHAEQMRCKELENAVGSWTDDL TQLTLLKDTLSAYISADDISILNERIELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEK NKELCEWLTQMESKVSQNGDILIEEMIEKLKKDYQEEIAVAQENKIQLQQMGERLAKASH ESKASEIEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESEL AKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDS IQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKTSERTAAFPSSS GVIYTVAKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQR WDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQ LKAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELRRYCQEVFGRVERYHK KLIRLPLPDDEHDLSDRELELEDSAALSDLHWHDRSADSLLSPQPSSNPSLSLAQPLRSE RSGRDTPASVDSIPLEWDHDYDLSRDLESAVSRALPSEDEESQDDKDFYLRGAVGLSDVM IPESPEAYVKLTENAIKNTSGDHSALESQIRQLGKALDDSRFQIQQTENIIRSKTPTGPE LDTSYKGYMKLLGECSGSIDSVKRLEHKLKEEEESLPGFVNLHSTETQTAGVIDRWELLQ AQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIELQIKKL KELQKAVDHRKAIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLLEEWRGLL QDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEILQDHHKQLMQIKHELLES QLRVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDVSSS QQDLSSWSSADELDTSGSVSPTSGRSTPNRQKTPRGKCSLSQPGPSVSSPHSRSTKGGSD SSLSEPGPDRSSRAFLFRVLRAALPLQLLLLLLIGLACLVPMSEEDYSCALSNNFARSFH PMLRYTNGPPPL NT seq 26499 nt NT seq  +upstreamnt  +downstreamnt atggcaacctccagaggggcctcccggtgtcctcgggatatcgccaatgtgatgcagagg ctgcaagatgagcaagagatagtacaaaaacgaactttcacaaaatggatcaactctcat ctggccaagcggaaacctccaatggtggtggatgatctttttgaagacatgaaagatggt gttaaactgcttgcccttctggaggtcctgtctgggcagaagctgccttgtgaacaagga cgccggatgaagcgaatccatgctgtggctaacattggcacggcactcaagttcctcgaa ggaagaaagtccatgcacagaggatcaccgattaaattagtcaacattaactccaccgat atagctgacggccgaccctcaatagttcttggattgatgtggaccattattctatatttc cagatcgaagagttgaccagcaacttgccccagctccagtctttgtccagcagcgcatcc tccgtggacagcatagttagctctgagactcccagcccaccaagtaaacggaaggtgacc accaagatccaaggaaatgctaagaaggctttattaaagtgggttcagtacacggctggc aagcagactggaatagaagtaaaagattttgggaagagttggagaagcggggttgccttt cattcagttattcatgccattcgacccgaactggtggacttggagaaagtgaaaggcaga tccaaccgagaaaatctggaggatgctttcactatcgccgaaacggaactggggatccca agactgctagatcctgaagatgttgatgtggataaaccagatgagaagtctattatgacc tatgtggcccagtttctgaaacattatcctgacatccacaatgcaggcactgatgggcaa gaggatgatgaaatacttccaggtttcccatcttttgcaaattctatacaaaattttaag agagaagacaggctaattttgaaggaaatgaaagtttggatagaacaatttgagagagat ttgacaagagcacagatggtggaatcaaatttacaggataaatatcagtcatttaagcac ttcagagttcaatacgaaatgaagaggaaacagattgaacatttagtacaaccattacat agagatggtaaattgtcacttgaccaagcattggtaaaacaatcttgggatagagtgact tccaggctctttgactggcatatacagcttgataaatctcttcctgcacctctgggcacc ataggtgcctggctgtacagagcggaggtggccctgagagaggaaataaccattcagcag gtccacgaggaaacagcaaacacgatacaacggaaacttgagcaacataaggatctgctt caaaacacagatgcccacaaaagagcattccatgaaatctaccggaccaggtctgttaac gggattccagtgccacctgatcaattagaggacatggccgagaggtttcattttgtttcc tccacatcggagctacacctaatgaaaatggaatttttagaattaaagtaccgtctgctt tcactgctggttcttgcagagtcaaagctgaagtcttggatcattaagtacgggaggaga gagtcagtggagcagcttctacaaaactacgtgtcttttatagaaaatagcaagttcttt gaacaatatgaagtgacataccagatcttgaaacagacagctgagatgtatgtcaaagca gaaggttcagtggaagaagctgagaatgtgatgaaattcatgaatgaaaccactgctcag tggaggaatctctcagtagaagttaggagtgtgaggagcatgctggaagaagtgatctct aactgggatcgctatggcaatacagtggctagtctgcaagcctggctagaggatgctgaa aaaatgctcaatcaatcagaaattgccaaaaaggatttttttcgaaatttacctcattgg attcagcagcatactgccatgaatgatgctggcaattttctaattgaaacctgtgatgag atggtttcccgtgacctgaagcagcaattactgttgctaaatgggcggtggagggagttg tttatggaagtcaagcaatatgctcaagctgatgagatggacagaatgaagaaggaatac acagactgtgtttttaccctgtctgcttttgcaacggaagcccataagaaattttgtgaa cccttagaagtctcttttatgaatgtcaagttattaattcaagacttggaggatattgag cagagggtgcctgtgatggatgcccaatacaagataattacaaagacagcacacctcatt accaaagaaagcccccaagaagaaggaaaagaaatgtttgcaacaatgtcaaagctcaaa gagcagctaaccaaggtcaaagaatgttactccccactcctttatgagtctcagcagctg ttgattccgttggaggaattagaaaagcagatgacgtccttttatgactcacttgggaaa atcaatgaaattatcacagttcttgagcgtgaagcacaatcgagtgctctttttaaacaa aaacatcaggaactgttagcttgtcaagaaaactgtaagaaaaccttgacacttattgag aaaggcagtcaaagtgttcaaaagtttgtgaccttgagcaacgtgttaaagcattttgat cagacgaggctacaaagacagattgcagatgttcatgttgcttttcagagtatggtaaag aaaactggagattggaagaagcatgtggaaaccaacagtcgcttgatgaagaagtttgag gagtctcgagcggagttggagaaggtgctgcggattgctcaggagggcttggaggaaaag ggggatccggaggagctcctgcggagacacactgagtttttcagtcagctggatcagagg gtgctcaatgcgttcctgaaagcttgtgatgaactcactgacatccttccagagcaggag cagcaggggcttcaggaagctgttcgaaagctccacaaacaatggaaggatcttcaagga gaagccccttatcatttgcttcatctgaagattgacgtggagaagaataggttcttagcc tctgtagaagaatgcagaactgagctggatcgagagaccaagctgatgccccaggaaggc agtgaaaagataattaaagagcacagggttttcttcagtgacaaaggtcctcatcatctc tgtgagaaaaggttacagctcattgaggaactctgtgtgaaactcccagtccgggatcca gtaagggacacacctggaacctgtcacgcgactctcaaagagctccgagctgccattgac agcacctacaggaagctcatggaagacccagacaagtggaaggactacactaacagattc tctgagttctcatcttggatatctacaaatgagacacaattaaaggggatcaagggtgag gccatcgatactgccaaccacagagaggttaaacgtgccgttgaagagatcagaaatggt gttaccaaaaggggcgagaccctcagctggctgaaatccaggctgaaagttttgacagaa gtttcttctgagaaccaagcccaaaagcagggagatgaattggcaaaattatccagctct ttcaaggctctggtgacgctgctgtcagaggttgaaaagatggtaagcaattttggggac tgtgtacagtacaaagaaatagtcaaaaattctcttgaagaattaatttctggctctaaa gaagtccaggaacaagctgagaagatcttggatactgaaaatctgtttgaagcacagcag ttacttcttcatcaccagcaaaagacaaagcggatctcagcaaagaagagagatgtgcag cagcagatcgcgcaggcgcagcaggaagaaggagggttgcctgaccgaggccgcgaggag ctgcggaagctggagagcaccctggacggcctggagcgaagccgggagaggcaggagcgc cgcatccaggtcacattaagaaaatgggagcgatttgaaacaaacaaagaaacagtagta agatacctttttcaaacaggttccagtcatgaacgcttcttaagttttagcagtttggaa agtttatcttcagaattggaacaaacaaaggagttctctaaacggacagaaaatattgca gtccaggctgagaaccttgtaaaggaagcttcagagataccacttgggccccaaaataag cagctgcttcaacagcaggcccagtcaatcaaagaacaagtcaaaaaattagaagacacg cttgaagaagatattaaaaccatggaaatggtgaaaaccaagtgggatcattttggcagt aattttgagactctgtccgtctggataactgagaaagaaaaagagctcaatgccttggaa acttcgtcatctgccatggacatgcaaatcagccaaattaaggtcacaattcaggaaata 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gagagcaaaaaggttgaattgcagagtctgcagggtcacttagcaaagttgggttctctg ggccgtgctgaggacctccacctcctgcagggcaaggctgaggactgcttccagctgttt gaggaggccagccaggttgtggagaggcggcagcttgccctgtcccatttggcagaattc ctccagagccatgcctctctgtccggcattctccaccagctgaggcaaacggtggaagca accaacagtatgaataagaacgagtctgatttgatagaaaaggacctcaatgatgctctt caagatgctaaagcattagaatctgctgctgtcagtctcgatggcattctttccaaagcc caataccatctgaaaagtgggagctctgagcaaaggacttcctgcagagccacggctgat cagctctgtggagaggtagaaaggatccagaaccttctgggaaccaagcagagtgaggca gatgccctggcagtgttgaaaaaagcattccaagaccagaaagaggagcttctgaaaagc attgaggacattgaagaaaggactgacaaagagcgactgaaagaacctacccgccaagct cttcagcagaggttaagagtgtttaatcagctagaagatgaattgaattctcacgagcat gaactatgttggttgaaagacaaagccaagcaaattgcccagaaagatgtagcttttgca cctgaagttgacagggagataaaccgcttagcagtcacctgggatgataccaaaagacta attcatgaaaatcagggtcaatgctgtggacttattgacttaatgagagaatatcagaac ctgaagtcaactgtatctaaagtcttagaaaatgccagcagtgtgattgtaaccagaact accattaaagatcaagaagatcttaaatgggctttttccaagcatgaaactgccaagaac 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aagattgacaaagtagatacaacaatgatggggaagaaattgaagacgttggaggttttg ctcaaagacatggagaaaggtcacagtttgctgaaatcagcccgggagaaaggagagagg gctgttaaatacttggaggaaggcgaggcagagaggttaagaaaggagattcatgatcac gtggagcagttgaaggaactgaccagcactgtccggaaagaacacatgacactggaaaaa ggtcttcatttagcaaaggaattctcagataaatgcaaagccctgacacagtggatagca gaataccaggaaatcctacgtgttcctgaagaacccaaaatggaattatatgagaaaaaa gctcagttatctaaatacaagtcacttcaacaaacggtgctgtcccatgaaccatcagta aagtcagtgagagagaagggtgaagctcttctggaactagtgcaggatgtcactttaaag gacaaaatagatcaacttcaaagtgattaccaggacctgtgcagcataggaaaggagcat gtcttcagtctggaggcgaaagtcaaagaccatgaagactacaacagtgagctccaagag gttgaaaagtggctgctgcagatgtccggcagactggtggcccctgacctcctggagaca agcagcctggagacaatcacccagcaactggcccaccacaaggcaatgatggaagaaatt gctggttttgaagaccgtttgaacaatcttcaaatgaaaggtgatactttgattggccaa tgtgcagaccacctgcaagcgaaacttaaacaaaacgtccatgctcatctgcagggtaca aaggacagctactcagcgatctgcagcacagctcagagggtgtaccagagtttggaacat gaacttcagaagcacgtcagccgacaagacaccctgcagcagtgccaggcctggctttct 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gaaatgttgcagctggcaggcaatggcctagatgtggagagcgcagaggaaaatctcaaa aaccacatggaatttttcagtacagaggatcagttccacagtaacctggaggagctccgc ggcctggtagccaccctggacccactcatcaagccaacaggcaaagaagacctagaacag aaaatggcttctctggaactcaggagccagaggatgagccaggactcttgtgcccaagtg gatctcttgcagagatgcacagctcaatggcacgattaccagaaagcaagggaagaggtt attgaattgatgaatgatacagaaaagaaattgtctgagttttctttgttgaagacttct tctagtgatgaagcagaagaaaaattgtcagagcacaaggctttagtgtcagtggttaac tctttccatgagaaaatcgtggcccttgaggaaaaagcttcacaactggagaaaaccgga aatgatgctagcaaagccaccctgagcaggtcaatgaccactgtctggcagcgctggaca cgccttcgagctgtggcccaagaccaggagaagatcctggaagatgcagtggatgagtgg acgggctttaacaacaaggttaaaaaggccactgaaatgattgatcagctgcaagataag ttacctggcagttcagcagagaaggcgtcgaaagcggaactcttaactcttcttgaatac cacgacacgttcgttctggagctggagcagcagcagtcggccttgggcatgctccggcag caagccctcagcatgctccaggatggagccgccccgacccccgggggagagccaccgctc atgcaggaaatcaccgcgatgcaagatcggtgcctgaacatgcaggagaaagtgaagact aatggaaagttggtgaagcaagagctgaaggaccgagaaatggtggagactcagatcaat 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accctgacttctccagaagttggacgtctcagtctcaaggagcagctctctcatcggcag catctgttgtctgagatggagtcactgaagccgaaggtgcaagcagtgcagctctgccag agtgccctccggatccccgaggatgtggtcgccagcttacctctgtgtcatgctgctctg cggctgcaggaagaggccagccggctgcagcacaccgccatccagcagtgcaacatcatg caggaggctgtggtgcagtatgaacaatatgagcaagaaatgaaacatctccagcaactc atagaaggagcccacagagagattgaggataaacctgttgccaccagtaacatacaggag ctgcaggctcagatttctcggcatgaggagctggcgcagaaaattaagggctaccaggag cagatcgcttctttgaattccaagtgcaagatgctgacgatgaaagccaagcacgccacc atgctgctgacggtgaccgaggtcgaggggctggcggaagggacagaggacctggacggg gagctcctccccgcgccttcggcccacccctctgtggtcatgatgactgcaggtcgctgt cacactttgctgtcaccggtcactgaggagtctggggaggagggaaccaacagtgagatt tcctctccacctgcctgtcgctccccttcacctgtggctaatacagatgcttctgttaac caggacattgcatattaccaagccttgtctgctgagaggttgcagacagatgccgcaaag attcaccccagcacatcagcgtcccaggagttgtatgaaccaggattggagccatccgct actgccaaactgggtgatttgcagcgttcttgggaaaccttaaagaatgtgatcagtgag aagcagcgcacactctatgaagctttggaacgccagcagaagtaccaggactccctccag tccatctctacgaagatggaggccattgagctgaaactcagtgagagcccagagcccggc aggagtccagaaagccagatggctgaacatcagtctttcctccaggcattgatggatgag attctcatgctccaggatgaaatcaatgagctccagtcctctctcgcagaggagctggta tccaagtcttgtgaggccgaccctgcggagcagctggccttgcagtccacgctcactgtc ttagccgagcgaatgtccaccatcaggatgaaagcctcagggaaacggcagcttttggag gagaagttgaatgatcagctggaggaacaaaggcaggaacaggccctgcagaggtatcgc tgtgaagccgatgagctggacagctggctcttgagtaccaaggccactctggatactgcg ctgggtacacccaaggagcccatggacatggaggcccagcttgtggactgccagaacatg ctggtggaaatagagcagaaggtggtggctttatcagagctgtcagtccacaatgagaac ctgctgctggagggcaaagctcacaccaaggacgaggccgagcagctggctggaaagctg agaaggctcaaggggagcctgctggagctgcagagagccctgcatgataagcagctcaac atgcagcagggaacagcacaggagaaggaggagagcgatgttgacctaacagccacgcag agccccggcgtccaggaatggctggcccaagctcgcaccacatggacccaccagcggcag agcagtctccagcaacaaaaagagttagaacaggaattagctgagcagaagagtctcctt cgctcagtagccagtcgtggagaggagattctaattcaacattcggccgcagagacctct ggtgacgctggcgaaaaacctgatgtgttatcccaggagttggggatggaaggggagaaa tcatccgctgaagaccagatgagaatgaaatgggaaagcttacatcaagaatttagtacc aagcagaaactactacagaatgttctggaacaggaacaagagcaagtgctttatagcagg ccaaatcgactcttgtctggtgtgccgctgtacaaaggggacgtgccgatccaagataaa tctgcagttacgtctttgctggatggactgaaccaggccttcgaggaggtttcatcccag agtggagggacaaagaggcagagtatacacttggagcagaagttatatgatggggtctca gccacctctacttggttggatgatgttgaagaacgtttatttgttgccacagcactttta ccagaagaaacagaaacttgtctcttcaaccaagagattcttgccaaagacattaaggaa atgtctgaagaaatggataagaacaaaaacttgttttcgcaagcttttccagagaatggt gataatcgagatgttattgaagatactttgggttgtcttttgggcaggttatccttgcta gactcagtagtgaatcaacgatgtcatcagatgaaagaaagacttcagcaaatactaaat ttccagaatgatctgaaagtgctgtttacatcactggctgacaacaaatacatcattctg cagaaactggcaaatgtatttgaacaacccgtagcagaacaaatagaggcaatacaacag gctgaagatggactcaaagaattggatgcaggaatcattgaattaaagagacgtggtgac aagttacagattgagcagccgtccatgcaagaactctccaagctccaggacatgtatgat gagctgatgatgaccattggctctcggaggagtggcctgaaccagaaccttacactcaag agtcagtatgagagggccctacaagatctggctgacttgctagaaactggtcaggagaag atggcaggagaccagaaaatcatcgtgtcttccaaagaggaaatccagcaactacttgac aaacataaggaatactttcagggcctggaatctcatatgatcttgactgaaacactcttc agaaagataatcagctttgcagtccagaaggaaacccagttccatacagagctgatggct caggcttctgctgtactgaaacgggctcacaagaggggtgtggagctggagtacattcta gagacgtggtcgcatctagatgaggaccagcaggagcttagcagacagctggaggtggtg gaaaacagcatcccaagcgtgggtctggtggaggagaacgaggacaggcttattgaccgc ataacactctaccagcatttaaaatctagccttaatgaataccagcccaaattatatcaa gtattagatgatggcaaacgacttctgatatccatcagctgctcagatctagaaagtcaa ctaaatcaacttggagagcgctggctaagtaacaccaacaaagtgtctaaggaacttcac agactggaaacaatattgaaacactggaccagatatcaaagtgaatctgcagatctaatt cactggttacagtctgcaaaagacaggctagaattttggactcagcaatctgtgacagtc ccacaagagctggaaatggtccgggatcatctaaatgctttcctggagttttctaaagaa gtggatgccaaatcttccctgaaatcatctgttctgagtactggaaatcagctccttcga ctgaaaaaggtggacacagccacgctgcgctctgagctgtcgcacattgatagccagtgg actgacctgctaaccaatatcccagccgtccaggagaagctccaccagctccagatggat aaactgccttcccgccatgccatttctgaagtcatgagctggatttctctaatggaaaat gttattcagaaggatgaagataatattaaaaattccataggttacaaggcaattcatgaa taccttcagaaatataagggttttaagatagacattaactgtaaacagctgacggtggat tttgtgaaccagtctgtgctacaaatcagcagtcaggatgtggaaagtaaacgtagtgat aagactgattttgctgagcaacttggagcaatgaataaaagttggcaaattctgcaaggt ctagtaactgagaagatccagctgttggaagggttattggaatcttggtcagaatatgaa aataatgtacaatgtctgaaaacatggtttgaaactcaggaaaagagactaaaacaacag catcgaattggagatcaggcttctgttcaaaatgcgctgaaagactgtcaggatctggaa gatttgattaaagcaaaagaaaaagaagtagagaaaattgagcagaatggacttgctttg atccagaacaagaaggaagacgtctctggcattgtcgtgggcacactgcaagggctcggc caaacctgggcgagtttagatcacatggttggacaattaaagatactgttgaaatcagtg cttgaccaatggagtaatcacaaagtggcctttgacaagataaacagttacctcatggag gccagatactctctttcccgattccgtctgctgactggctccttagaagctgtgcaagtt caggtggacaatcttcagaatctccaagatgatctagaaaaacaggaaaggagcttacag aaatttggctctatcaccaaccaattattaaaagagtgccacccgcctgtgacagaaact cttaccaatacactgaaagaagtcaacatgagatggaataacttgctggaagagattgct gagcagctacactccagcaaggccctacttcagctttggcaaagatacaaggactactcg aaacagtgtgcttcgtcggttcagcagcaggaggatcgaaccaatgagctgttgaaggca gccacaaacaaggacatcgccgatgatgaggttgctacatggattcaagattgcaacgac ctcctcaaaggactgggtacagttaaagactccctctttgttctccatgagctgggagag caactgaagcaacaagtggatgcttcagcagcatcagctcttcaatcggatcaactctct ttgagtcaacacttgtgtgccctagagcaggctctctgcaaacagcagacttcgttacag gctggagttcttgattacgaaacctttgccaagagtttagaagctctggaggcctggata gtggaagctgaagaaatactacaagggcaggaccctagccattcatctgacctctccaca atccaggaaaggatggaagaacttaagggacagatgttaaaattcagcagcatggctcca gatttagaccgtctaaatgagcttggatatagattacccttgaatgataaggaaatcaaa aggatgcagaatctgaaccgccattggtctctgatctcctctcagactacagaaagattc agcaagttgcagtcatttttgctacaacatcagactttcttggaaaaatgtgaaacatgg atggagttcctagttcagacagaacaaaagttagcagtagagatttcaggaaattatcag catcttttggaacagcagagagcacatgagttgtttcaagccgagatgttcagtcgtcag cagattttgcactcaatcattattgatgggcaacgtcttctagaacaaggtcaagttgat gacagggatgaattcaacctgaaattgacactcctcagtaatcagtggcagggagtgatt cgcagggcccagcagaggcgggggatcattgacagccagattcgccagtggcaacgctat agggagatggcagaaaagcttcgtaaatggttggttgaagtgtcctacctccccatgagt ggtctcggaagtgttcctataccactgcaacaagcaaggaccctctttgatgaagtgcag ttcaaagaaaaggtgttcctgcggcaacaaggcagctacatcctgactgtggaggctggc aagcaactccttctgtctgcggatagtggcgctgaggccgctttgcaggccgaactcact gaaatccaagagaaatggaaatcagccagcgtgcggctggaagaacagaagaaaaaacta gccttcttgttgaaagactgggaaaaatgtgagaaaggaatagcagattccctggagaaa ctacgaactttcaaaaagaagctttcccagtgtctaccggatcaccacgaagagctccat gcagaacaaatgcgttgcaaggaattagaaaatgcagttgggagctggacagatgacttg acccagttgacgctgctgaaggacaccctctctgcctacatcagtgctgatgatatctcc attcttaatgaacgcatagagcttctgcaaaggcagtgggaagaactatgccaccagctc tccttaaggcggcagcaaataggtgaaagattgaacgaatgggcagtcttcagtgaaaag aacaaggaactctgtgagtggttgactcaaatggaaagcaaggtttctcagaatggagac attctcattgaagaaatgatagagaagctcaagaaggattatcaagaggaaattgctgtt gctcaagagaacaaaatacagctccaacaaatgggagaacgacttgctaaagccagccat gaaagcaaagcatctgagattgaatacaaactgggaaaggttaacgaccggtggcagcat ctcctggacctcattgcagccagggtgaagaagctgaaggagaccctggtggccgtgcag cagctcgataagaacatgagcagcctgaggacctggctcgctcacattgagtcagagctg gccaagccaatagtctacgattcctgtaactcggaagaaatacagagaaagcttaatgag cagcaggaacttcagagagacatagagaagcacagtacaggtgttgcttctgtcctcaac ctgtgtgaagtcctgctgcacgactgtgatgcctgtgccactgatgccgagtgtgactct atccagcaggctacaagaaacctggaccggcggtggagaaacatttgtgctatgtccatg gaaaggagactcaaaatcgaagagacgtggcgattgtggcagaaatttctggatgactat tcacgttttgaagattggctgaagacttcagaaaggacagctgcatttcccagctcttct ggggtaatctatacagttgccaaggaagaactaaagaaatttgaggctttccagcgacag gtccacgagtgcctgacgcagctggaactgatcaacaagcagtaccgccgcctggccaga gagaaccgcactgattcagcctgtagcctcaaacagatggttcacgaaggcaaccagaga tgggacaacctgcaaaagcgcgtcacctccatcttgcgcagactcaagcattttattggc cagcgtgaggagtttgagactgcgcgggacagcattctggtctggctcacggagatggat ctgcagctcactaatattgaacatttttctgagtgtgatgttcaagctaaaataaagcaa ctcaaggccttccagcaggaaatttccctgaaccacaataagattgagcagataattgcc caaggagaacagctgatagaaaagagtgagcccttggatgcggcgatcatcgaggaggaa ctagacgagctccgacggtactgccaggaggtcttcgggcgtgtggaaagataccataag aaactgatccgcctgcctctcccagatgatgagcacgacctctcagacagagagctggag ctggaagactctgcggctctgtcggacctgcactggcatgaccgctctgcagacagcctg ctttctccacagccttcctccaacccctccctgtcgctcgctcagcccctccggagcgag cggtcgggacgagacaccccggctagtgtggactccatccccctggagtgggatcacgac tatgacctcagtcgggacctggagtctgcagtgtccagagctctgccctctgaggatgaa gagagtcaggacgacaaagatttctacctccggggagctgttggcttatcagatgtaatg atccctgaaagccctgaggcctatgtaaaactcacagaaaatgcaatcaaaaatacctct ggggaccacagcgccctagagtcacagatccgacaactgggcaaagccctggatgatagc cgctttcagatacagcaaaccgaaaatatcattcgcagcaaaactcccacggggccagag ctagacaccagctacaaaggctacatgaaactgctgggcgaatgcagtggcagtatagac tccgtgaagagactggagcacaaactgaaggaggaagaggagagccttcctggctttgtt aacctgcatagtaccgaaacccaaacggctggtgtgattgaccgatgggagcttctccag gcccaggcgttgagcaaggagctgaggatgaagcagaacctccagaagtggcagcagttt aactcggacttgaacagcatctgggcctggctgggggacacggaggaggagctggaacag ctccagcgtctggaactcagcactgacatccagacaatcgagctccagatcaaaaagctc aaggagctccagaaagccgtggaccaccgcaaagccatcatcctctccatcaatctctgc agccctgagttcacccaggctgacagcaaggagagtcgggacctgcaggatcgcttgtca cagatgaatgggcgctgggaccgagtgtgttctctgctggaggagtggcggggcctactg caagatgccctgatgcagtgccagggtttccatgaaatgagccatggtttgcttcttatg ctggagaacattgacagaaggaaaaatgaaattgtccctattgattctaaccttgatgca gagatacttcaggaccatcacaaacagcttatgcaaataaagcatgagctgttggaatcc caactcagagtagcctctttgcaagacatgtcttgccaactactggtgaatgctgaagga acagactgtttagaagccaaagaaaaagtccatgttattggaaatcggctcaaacttctc ttgaaggaggtcagtcgtcatatcaaggaactggagaagttattagacgtgtcaagtagt cagcaggatttgtcttcctggtcttctgctgatgaactggacacctcagggtctgtgagt cctacatcaggaaggagcaccccaaacagacagaaaacgccacgaggcaaatgtagtctc tcacagcctggaccctctgtcagcagtccacatagcaggtccacaaaaggtggctccgat tcctccctttctgagcctgggccagatcggtccagccgcgccttcctgttcagagtcctc cgagcagctcttccccttcagcttctcctgctgctcctcatcgggctcgcctgccttgta ccaatgtcagaggaagactacagctgtgccctctccaacaactttgcccggtcattccac cccatgctcagatacacgaatggccctcctccactctga

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