Macaca mulatta (rhesus monkey): 712096
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Entry
712096 CDS
T01028
Symbol
ARHGEF12
Name
(RefSeq) rho guanine nucleotide exchange factor 12 isoform X2
KO
K07532
Rho guanine nucleotide exchange factor 12
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc04270
Vascular smooth muscle contraction
mcc04360
Axon guidance
mcc04611
Platelet activation
mcc04625
C-type lectin receptor signaling pathway
mcc04810
Regulation of actin cytoskeleton
mcc05135
Yersinia infection
mcc05152
Tuberculosis
mcc05163
Human cytomegalovirus infection
mcc05200
Pathways in cancer
mcc05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
712096 (ARHGEF12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
712096 (ARHGEF12)
04625 C-type lectin receptor signaling pathway
712096 (ARHGEF12)
09153 Circulatory system
04270 Vascular smooth muscle contraction
712096 (ARHGEF12)
09158 Development and regeneration
04360 Axon guidance
712096 (ARHGEF12)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
712096 (ARHGEF12)
05205 Proteoglycans in cancer
712096 (ARHGEF12)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
712096 (ARHGEF12)
09171 Infectious disease: bacterial
05135 Yersinia infection
712096 (ARHGEF12)
05152 Tuberculosis
712096 (ARHGEF12)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mcc04131
]
712096 (ARHGEF12)
Membrane trafficking [BR:
mcc04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
712096 (ARHGEF12)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RGS-like
PH_16
RhoGEF
PDZ
PDZ_6
PDZ_2
PH_13
SOS1_NGEF_PH
Pept_S41_N_bact
AAA_23
Motif
Other DBs
NCBI-GeneID:
712096
NCBI-ProteinID:
XP_014971452
Ensembl:
ENSMMUG00000012254
UniProt:
A0A1D5R2Y9
LinkDB
All DBs
Position
14:113406660..113555066
Genome browser
AA seq
1544 aa
AA seq
DB search
MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERIASHDFDPTDSSSKKTKSSSEE
SRSEIYGLVQRCVVIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT
LVTHSNHLEVVKLIRSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPG
ASGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQ
EAKKHIPQLQEQLSKATGSAQDGAVVTPSRPLGDTLTVSEAETDPGDGLGRTDCSSGDAS
RPSSDNADSPKSGPKERIYLEENPEKSETIQDTDTQSLVGSPSTRIAPHIIGAEDDDFGT
EHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRR
IFLEFHQFFLDRSAHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHL
EDFRQKRSMGLTLAESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEILMTAQAVEEDK
SSTMQYVILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDKEGEEKGKRRGFPSI
LGPPRRPSRHDNSAIGRAMELQKARHPKHLSTPSSVSPEPQDSAKVRQSGLANEGIDAGY
LPANSVSSVASGASFSQEGGKENDTGSKQVGETPAPGDTLDGTPRTINTVFDFPPPPLDQ
VQEEECEVERVTEHGTPKPFRKFDSVAFGESQSEDEQFENDLETDPPNWQQLVSREVLLG
LKPCEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQ
LHIGLNEQMKAVRKRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKS
RQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIGKYTEWPTEREKV
KKAADHCRQILNYVNQAVKEAENKQRLEDYQRRLDTSSLKLSEYPNVEELRNLDLTKRKM
IHEGPLVWKVNRDKTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVI
KLSTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTK
PIPLPQSTPGEGDNDEEDPSKLKEEQHGISVTGLQSPDRDLGLEATLISSKPQSHSLSTS
GKSEVRDLFVAERQFAKEQHTDGTLKEVGEDYQITIPDSHLPVSEERWALDALRNLGLLK
QLLVQQLGLTEKSAQEDWQHFPRYRTASQGPQADSVIQNSENIKAYHSGAGHMPFRTGTG
DTATCYSPRTSTESSTPRDSVGLAPQDSQASNILVMDHMIMTPEMPTMEPEGGLDDSGEH
FFDAREAHSDENPSEGDGAVNKEDKDVNLRISGNYLILDGYDPVQESSTDEEVASSLTLQ
PMTGIPAMESTHQQQHSPQNTHSDGAVSPFTSEFLVQQRWGAMEDSCFEIQSPSSCADSQ
SQIMEYIHKIEADLEHLKKVEESYTILCQRLAGSALTDKHSDKS
NT seq
4635 nt
NT seq
+upstream
nt +downstream
nt
atgagtggcacacagtctactatcaccgacaggtttcccctcaaaaaacctataaggcat
ggaagtattttgaaccgagagtcaccaacagataagaagcagaaagttgagcgcattgca
tcacatgattttgaccccacagatagctcctccaagaagacaaagtctagttcagaggag
agtagatccgagatatatggtcttgttcaacgttgcgtagtcatccagaaagatgacaat
ggatttgggctgacggtcagtggagacaatccagtcttcgtacagtctgtcaaagaagat
ggagcagccatgcgggctggagtacagacaggtgatcgaatcatcaaggtgaatggaact
ctggtgactcattcaaatcatctggaggtggtgaagctaatcagatctggttcctatgta
gctctcactgttcagggacgcccacctgggtcgccccagattccacttgccgactctgaa
gtagagccatcagtcattggacatatgtctcccatcatgacatctcctcattcacctgga
gcatctgggaatatggagagaatcactagtcctgtgctcatgggggaggaaaacaatgtg
gttcataaccagaaagtagaaattctgagaaaaatgttacagaaagaacaggaacggcta
cagttattgcaggaagattacaaccgaacacctgcccaaagattgctaaaagagatccaa
gaggccaagaaacacattcctcagctgcaagagcagttatccaaagccacaggctctgct
caggatggagctgtagttacaccctccagacctttaggtgacaccctaacagtcagtgag
gcagaaacagatcctggagatggcctgggcaggactgactgtagcagtggagatgcttct
cggcccagtagtgacaatgcagatagtcccaagagtggccccaaagagaggatttatcta
gaggaaaacccagagaaaagtgaaacaattcaggacactgacactcaatcacttgtcgga
agtccctcaacccgtatagcacctcatattattggagcagaagatgatgattttggtact
gaacatgaacagatcaatggacagtgcagctgtttccagagcattgaattactaaaatct
cgcccggctcatttggctgttttcttacaccatgtagtttcacaatttgaccctgcaact
ttgctctgttatctctattcagacctgtataaacataccaattccaaggaaactcgtcgc
atcttccttgagtttcatcagttctttctagatcgatcagcacacctgaaagtttctgtt
cctgatgaaatgtctgcagatctagaaaagagaagacctgagctcattcctgaggatctg
catcgccactatatccaaactatgcaagaacgagtccatccagaggttcaaaggcactta
gaagattttcggcagaaacgtagtatgggactgaccttggctgaaagcgagctgactaaa
cttgatgcagagcgagacaaggaccggttgactttggagaaggagcggacatgtgcagaa
cagattgttgccaaaattgaagaaatactgatgactgctcaggctgtagaggaagataag
agttccaccatgcagtatgttattctcatgtatatgaagcatttgggagtaaaagtgaaa
gagcctcgaaatttggagcacaaacggggtcggattggatttcttcccaaaatcaagcaa
agtatgaagaaagataaagaaggggaagaaaaagggaagcgaagaggatttcccagcatc
ctgggacccccacggagaccaagccgtcatgacaacagtgcaattggcagagccatggaa
ctacagaaggcgcgccaccctaagcacttatccacaccctcatctgtgagtcctgaacct
caggactctgccaaggtgcgccagagcgggttagcaaatgaaggaatagacgctggatac
ctgcctgccaattccgtgtcttctgtggcttcaggggcctctttttcccaggaaggaggg
aaagagaatgatacaggatcaaagcaagttggagaaacaccagcacctggagacacctta
gatggcacacctcgtactatcaatactgtctttgatttcccaccacctccattagaccaa
gtgcaggaggaggaatgtgaagtagaaagggtgactgaacatgggacaccaaagcccttt
cgaaagtttgacagtgtagcttttggagaaagtcaaagtgaggatgaacaatttgaaaac
gacttagagacagatccacccaactggcagcagcttgttagtcgagaagtgttattggga
ctaaaaccttgtgagatcaaaagacaggaagtgattaatgaattgttctacactgaaaga
gctcatgttcgaacactgaaggttcttgatcaagtgttctatcagcgagtgtccagagaa
ggaattctgtcaccctcagagctacggaaaattttttcaaacttggaagatattcttcaa
cttcatattggattgaatgaacaaatgaaggctgttcgaaagagaaatgagacctctgtt
atcgatcagattggggaagatttgctgacatggttcagcggaccaggagaggagaaattg
aaacatgctgctgctaccttttgcagtaaccaacctttcgccctggaaatgatcaagtct
cgtcagaaaaaggattctcgatttcagacttttgtgcaagatgctgaaagtaatccactg
tgtcgtcgtcttcaactgaaggatattattcccactcaaatgcaaaggcttactaagtac
ccacttctattggataatattggcaaatacacagaatggccaacagaaagggagaaggtg
aagaaagctgcagatcactgtcgtcagatcttaaattatgtaaatcaggctgtcaaggag
gcagaaaacaagcagcgcctcgaagattatcagcgtcgccttgatacctccagcctgaag
ttgtcagagtacccaaatgttgaagagctcaggaatttggatttaacaaaaaggaagatg
attcatgaaggaccattggtttggaaggtgaatagagataaaactattgatttatacaca
ttgctgctggaagacattcttgtattgttacaaaagcaggatgatagactggtgttaagg
tgtcatagtaagattctggcatctacagctgatagcaaacatacgtttagccctgtcatt
aaattgagtacagtgttggttcgacaagtggcaacagataacaaagctttattcgtcatc
tccatgtcagacaatggagctcagatttatgaactggtggcacagacagtttctgaaaag
actgtctggcaggacctaatctgtcggatggctgcatcagtgaaggagcaatccacaaag
ccaattccattaccccagtcaacacctggcgaaggagataatgatgaagaagatccttca
aaattaaaagaggaacagcatggcatttcagtcactggtttgcagagtccagacagagat
ttgggattagaagctaccttaatatcatcaaaacctcagtctcattcactgagtacttct
gggaaatcagaggtacgtgatctctttgtggctgagagacagtttgcaaaggaacaacat
acagatgggacactaaaggaagttggagaagattatcaaatcacaatcccagattcacac
ctgcctgtctcagaagaacgatgggcattggatgcactaagaaatttgggtttgttgaag
cagttgctggtgcagcagctcggtttgactgagaagagcgctcaggaagactggcaacat
ttcccaagatataggacagcctctcaggggccgcaggcagacagcgtcatccagaactct
gaaaatattaaggcctatcattctggtgcaggacatatgccctttagaactggaactggt
gacactgcaacttgttacagtcctcggacttcaactgaatcttccactccacgggattca
gtgggactggcaccccaggatagccaggcaagtaacattttagtaatggaccacatgatt
atgaccccagagatgcctaccatggagccagaagggggtcttgatgacagtggagagcac
ttttttgatgcccgtgaagcacatagtgatgagaatccatcagaaggtgatggagcagtt
aacaaggaagataaggatgttaatttacgcatctcaggaaactatttgatccttgatggc
tatgacccagtgcaggagagttccacagatgaggaggttgcgtcctcacttactctgcag
cccatgacaggcatccctgctatggaatccacccaccagcagcaacattctcctcagaac
actcactctgatggggcagtttcaccattcacctctgaatttctggtccagcagcgctgg
ggagctatggaggattcctgttttgagatccagagtccctcctcttgtgcagattcgcag
agccagatcatggagtacattcataagatagaggctgaccttgaacacttaaagaaggtg
gaggaaagttacaccattctttgccaaaggctggctggatcagccctcacagacaagcac
tcagataaaagttag
DBGET
integrated database retrieval system
