Macaca mulatta (rhesus monkey): 712180
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Entry
712180 CDS
T01028
Symbol
PDE4D
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X8
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc00230
Purine metabolism
mcc01100
Metabolic pathways
mcc04024
cAMP signaling pathway
mcc04928
Parathyroid hormone synthesis, secretion and action
mcc05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
712180 (PDE4D)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
712180 (PDE4D)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
712180 (PDE4D)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
712180 (PDE4D)
Enzymes [BR:
mcc01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
712180 (PDE4D)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE4_UCR
Motif
Other DBs
NCBI-GeneID:
712180
NCBI-ProteinID:
XP_001101097
Ensembl:
ENSMMUG00000012132
UniProt:
F7GZV4
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Position
6:complement(57315151..58848161)
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AA seq
687 aa
AA seq
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MAFVWDPLGATVPGPSTGAKSRLRFSKSYSFDVDNGTSAGRSPLDPMTSPGSGLILQANF
VHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAA
LTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSE
MASNKFKRMLNRELTHLSEMSRSGNQVSEFISNTFLDKQHEVEIPSPTQKEKEKKKRPMS
QISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTV
IMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPA
LEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKL
LQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLL
DNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDK
HNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDD
PEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDE
QVEEEAVGEEEESQPEACVIDDRSPDT
NT seq
2064 nt
NT seq
+upstream
nt +downstream
nt
atggcttttgtttgggatcctctgggagccacagtgccaggaccgtctacaggagccaaa
tcaagattgcgtttctcaaagtcctacagttttgatgtggacaatggcacatctgcggga
cggagtcccttggatcccatgaccagcccaggatctgggctaattctccaagcaaatttt
gtccacagtcaacgccgggagtccttcctgtatcgatctgacagcgattatgacctctct
ccaaagtctatgtcccggaactcctccattgccagtgatatacacggagatgacttgatt
gtgactccatttgctcaggtcttggccagtctgcgaactgtacgaaacaactttgctgca
ttaactaatttgcaagatcgagcacctagcaaaagatcacccatgtgcaaccaaccatcc
atcaacaaagccaccataacagaggaggcctaccagaaactggccagcgagaccctggag
gagctggactggtgtctggaccagttagagaccctacagaccaggcactccgtcagtgag
atggcctccaacaagtttaaaaggatgcttaatcgggagctcacccatctctctgaaatg
agtcggtctggaaatcaagtgtcagagtttatatcaaacacattcttagataagcaacat
gaagtggaaattccttctccaactcagaaggaaaaggagaaaaagaaaagaccaatgtct
cagatcagtggagtcaagaaattgatgcacagctctagcctgactaattcaagtattcca
aggtttggagttaaaactgaacaagaagatgtccttgccaaggaactagaagatgtgaac
aaatggggtcttcatgttttcagaatagcagagttgtctggtaaccggcccttgactgtt
atcatgcacaccatttttcaggaacgggatttattaaaaacatttaaaattccagtagat
actttaattacatatcttatgactctcgaagaccattaccatgctgatgtggcctatcac
aacaatatccatgctgcagatgttgtccagtctactcatgtgctattgtctacacctgct
ttggaggccgtgtttacagatttggagattcttgcagcaatttttgccagtgcaatacat
gatgtagatcatcctggtgtgtccaatcaatttctgatcaatacaaattctgaacttgcc
ttgatgtacaacgattcctcggtcttagagaaccatcatttggctgtgggctttaaattg
cttcaggaagaaaactgtgacattttccagaatttgaccaaaaaacaaagacaatcttta
aggaaaatggtcattgacattgtacttgcaacagatatgtcaaaacacatgaatctacta
gctgatttgaagactatggttgaaactaagaaagtgacaagctctggagttcttcttctt
gataattattccgataggattcaggttcttcagaatatggtgcattgtgcagatctgagc
aacccaacaaagcctctgcaactgtaccgccagtggacggaccggataatggaggagttc
ttccgccaaggagaccgagagagggaacgtggcatggagataagccccatgtgtgacaag
cacaatgcttccgtggaaaaatcacaggtgggcttcatagactatattgttcatcccctc
tgggagacatgggcagacctcgtccaccctgacgcccaggacattttggacactttggag
gacaatcgtgaatggtaccagagcacaatccctcagagcccctctcctgcacctgatgac
ccagaagagggccggcagggtcaaactgagaaattccagtttgaactaactttagaggaa
gatggtgagtcagacacagaaaaggacagtggcagtcaagtggaagaagacactagttgc
agtgactccaagactctttgtactcaagactcggagtctactgaaattcccctcgatgaa
caggttgaagaggaggcagtaggggaagaagaggaaagccagcctgaagcctgtgtcata
gatgatcgttctcctgacacgtaa
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