Macaca mulatta (rhesus monkey): 712850
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Entry
712850 CDS
T01028
Symbol
PDE4A
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X1
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc00230
Purine metabolism
mcc01100
Metabolic pathways
mcc04024
cAMP signaling pathway
mcc04928
Parathyroid hormone synthesis, secretion and action
mcc05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
712850 (PDE4A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
712850 (PDE4A)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
712850 (PDE4A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
712850 (PDE4A)
Enzymes [BR:
mcc01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
712850 (PDE4A)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
PDE4_UCR
Motif
Other DBs
NCBI-GeneID:
712850
NCBI-ProteinID:
XP_014978339
Ensembl:
ENSMMUG00000016122
UniProt:
F6X2P4
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Position
19:10177784..10231870
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AA seq
886 aa
AA seq
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MEPPTVPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAEPERP
PHRPIERADAMDTSDRPGLRTTRMSWPSSFHGTGTGSSGAGGGSSRRFETENGPTPPPGR
SPLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTP
FAQVLASLRSVRSNFSLLTNVPVPTNKRSPLGGPTPVCKATLSEETCQQLARETLEELDW
CLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEI
PSPTMKEREKQQALRPRPSQPPPPPVPHLQPMSQITGVKKLMHSNSLNNSNIPRFGVKTD
QEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYML
TLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGV
SNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDM
VLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLE
LYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL
VHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEESRGPGHPPPPDKFQFELTLEEEEEEE
ISMAPIPCTAQEALTAQGLSGAEEALDTTVAREASPAQESLDVMAQDESLEAELEEVYLT
QQAQSTGSAPVAQDEFSSQEESVVAVSQSSLSALALQSPLLPAWRTLSVSEHAPGLPGLP
STAAEVEAQREHQAAKRACSACTGTSGEDTSALPAPGGGGSGGDPT
NT seq
2661 nt
NT seq
+upstream
nt +downstream
nt
atggagcccccgaccgtcccctcggaaaggagcctgtctctgtcactgcctgggccccgg
gagggccaagccaccctgaagcctccccctcagcacctgtggcggcagcctcggaccccc
atccgtatccagcagcgcggctactccgacagcgcggagcgcgcagagccggagcggccg
cctcaccggcccatagagcgcgccgatgccatggacaccagcgaccggcccggcctgcgc
acgacccgcatgtcctggccctcgtccttccatggcactggcaccggcagcagcggcgcg
ggcggaggcagcagcaggcgcttcgagacagagaatgggccgacaccacctcctggccgc
agccccctggactcgcaggcgagcccaggactcgtgctacatgccggggcggccaccagc
cagcgccgggagtccttcttgtaccgctcggacagcgactatgacatgtcacccaagacc
atgtcccggaactcatcggtcaccagcgaggcgcacgctgaagacctcatcgtaacaccg
tttgctcaggtgctggccagcctccggagcgtccgtagcaacttctcactcctgaccaat
gtgcccgttcccactaacaagcggtccccgctgggcggccccacccctgtctgcaaggcc
acgctgtcagaagaaacgtgtcagcagttggcccgggagacgctggaagagctggactgg
tgtctggagcagctggagaccatgcaaacttaccgctctgtcagcgagatggcctcgcac
aagttcaagaggatgttgaaccgtgaactcacacacctgtcagaaatgagcaggtcggga
aaccaggtctcagagtacatttccacaacattcctggacaaacagaatgaagtggagatc
ccgtcacccacgatgaaggaacgagaaaaacagcaagcgctgcgaccaagaccgtcccag
ccgcccccgccccctgtaccacacttacagcccatgtcccaaatcacaggggtgaaaaag
ttgatgcatagtaacagcctgaacaactctaacattccccgatttggggtgaagaccgat
caagaagagctcctggcccaagaactggagaacctgaacaagtggggcctgaacatcttt
tgcgtgtcagattacgccggaggccgctcgctcacctgcatcatgtacatgatattccag
gagcgggacctgctgaagaaattccgcatccctgtggacacgatggtgacatacatgctg
acgctggaggatcactaccacgctgacgtagcctaccataacagcctgcacgctgccgac
gtactgcagtccacccacgtactgctggctacgcctgcgctagatgcagtgttcacggac
ctggagattctcgccgccctcttcgcggctgccatacacgatgtagatcaccctggggtc
tccaaccagttcctcatcaacaccaattcggagctggcgctcatgtacaacgatgagtcg
gtgctcgagaatcaccacctggccgtgggcttcaagctgctgcaggaggacaactgcgac
atcttccagaacctcagcaagcgccagcggcagagcctacgcaagatggtcatcgacatg
gtgctggctacggacatgtccaagcacatgaccctcctggctgacctgaagaccatggtg
gagaccaagaaagtgaccagctcgggggtcctgctgctggataactactccgaccgcatc
caggtcctccggaacatggtgcactgcgcagacctcagcaaccccaccaagccgctggag
ctgtaccgccagtggacggaccgcatcatggccgagttcttccagcagggtgaccgtgag
cgcgagcgtggcatggaaatcagccccatgtgtgacaagcacactgcctccgtggagaag
tctcaggtgggttttattgactacattgtgcacccattgtgggagacctgggcagacctt
gtccacccagacgcccaggagatcctggacactttggaggacaaccgggactggtactac
agcgccatccggcagagcccgtcgccgccacctgaggaggagtcaagggggccaggtcac
ccacccccacctgataagttccagtttgagctgactctggaggaggaagaagaggaagaa
atatcaatggccccgataccgtgcacagcccaagaggcattgacagcgcagggattgtca
ggagccgaggaagctctggatacaaccgtggcccgggaggcatccccagcgcaggagtca
ttggatgttatggcacaggatgagtccctggaggccgagctggaggaagtgtatttgaca
cagcaggcacagtccacaggcagtgcacctgtggctcaggatgagttctcgtcccaggaa
gaatccgtggttgctgtaagccagagcagcctctccgccctggctcttcaaagccccctt
ctccctgcctggaggaccctgtctgtttcagagcatgccccgggcctcccgggcctcccc
tccacggcggccgaggtggaggcccaacgagagcaccaggctgccaagagggcttgcagt
gcctgcacagggacatctggggaggacacatctgcactcccagctcctggtgggggaggg
tcaggtggagaccctacctga
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