Macaca mulatta (rhesus monkey): 714433
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Entry
714433 CDS
T01028
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc00260
Glycine, serine and threonine metabolism
mcc00630
Glyoxylate and dicarboxylate metabolism
mcc00670
One carbon pool by folate
mcc01100
Metabolic pathways
mcc01200
Carbon metabolism
mcc01230
Biosynthesis of amino acids
mcc01240
Biosynthesis of cofactors
mcc01523
Antifolate resistance
mcc04981
Folate transport and metabolism
Module
mcc_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
714433 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
714433 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
714433 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
714433 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
714433 (SHMT2)
Enzymes [BR:
mcc01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
714433 (SHMT2)
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GFIT
Motif
Pfam:
SHMT
Motif
Other DBs
NCBI-GeneID:
714433
NCBI-ProteinID:
XP_015007584
Ensembl:
ENSMMUG00000021785
UniProt:
A0A8J8Y9U0
G7N7F2
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All DBs
Position
11:56795837..56801444
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AA seq
513 aa
AA seq
DB search
MSGVLGLASQAEPFRPALSPADDATEPHCLHQTGVPAAVRVGRRWNGLCRDGGSWSGWPF
GLSTARQPRLRLGKQTGAGQARRACRTVILRCGSCCRGRRTGSVVAWSSLPQRYYGGAEV
VDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGH
LTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYDQLALTARLFRPRLIIAGTSAYARL
IDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIF
YRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYS
LQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNT
CPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKTKTAKLQDFKSF
LLKDSETSQRLADLRQRVEQFARGFPMPGFDEH
NT seq
1542 nt
NT seq
+upstream
nt +downstream
nt
atgagtggagttctcggcctggcctcacaagctgagccttttcggccagctctgagccct
gcagatgatgcaaccgagcctcactgcttgcatcagacaggggtcccggcggcagtgagg
gttggaaggaggtggaacggcctctgcagagatgggggcagctggtcaggatggccattc
gggctcagcacagcaaggcagcccagactcagactggggaagcaaacaggggctggacag
gccaggagagcctgtcggacagtgatcctgagatgtgggagttgctgcagagggagaagg
acaggcagtgtcgtggcctggagctcattgcctcagagatattatgggggagcagaggtg
gtggatgaaattgagctgctgtgccagcgccgggccttggaagcctttgacctggatcct
gcacagtggggagtcaatgtccagccctactctgggtccccagccaacctggctgtctat
acagcccttctgcaacctcatgaccggatcatggggctggacctgcccgatgggggccat
ctcacccacggctacatgtctgacgtcaagcggatatcagccacgtccatcttcttcgag
tctatgccctataagctcaatcccaaaactggcctcattgactatgaccagctggcactg
actgctcgacttttccgaccgcggctcatcatagctggcaccagtgcctatgctcgcctc
attgactatgcccgcatgagagaggtgtgtgatgaagtcaaagcacacctgctggcagac
atggctcacatcagtggcctggtggctgccaaggtgattccctcgcctttcaagcacgcg
gacatcgtcaccaccactactcacaagactcttcgaggggccaggtcagggctcatcttt
taccggaaaggggtgaaggctgtggaccccaagactggccgggagatcccttacacattt
gaggaccgaatcaactttgctgtgttcccatccctgcaggggggcccccacaatcatgcc
attgctgcagtagctgtggccctaaagcaggcttgcacccccatgttccgggagtactcc
ctgcaggttctgaagaatgctcgggccatggcggatgccctgctagagcgaggctactca
ctagtatcgggtggtactgacaatcacctggtgctggtggacctgcggcccaagggcctg
gatggagctcgggctgagcgggtgctggagcttgtatccatcactgccaacaagaacacc
tgtcctggagaccgaagtgccatcacaccggggggcctgcggcttggggccccggccttg
acttctcgacagttccgtgaggatgacttccggagagttgtggactttatagatgaaggg
gtcaacattggcttagaggtgaagactaagactgccaagctccaggatttcaaatccttc
ctgctcaaggactcagaaacaagtcagcgtctggccgacctcaggcaacgggtggagcag
tttgccaggggcttccccatgcctggttttgatgagcattga
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