KEGG   Macaca mulatta (rhesus monkey): 714952
Entry
714952            CDS       T01028                                 
Symbol
TGFBR1
Name
(RefSeq) TGF-beta receptor type-1 isoform X2
  KO
K04674  TGF-beta receptor type-1 [EC:2.7.11.30]
Organism
mcc  Macaca mulatta (rhesus monkey)
Pathway
mcc04010  MAPK signaling pathway
mcc04060  Cytokine-cytokine receptor interaction
mcc04068  FoxO signaling pathway
mcc04144  Endocytosis
mcc04218  Cellular senescence
mcc04350  TGF-beta signaling pathway
mcc04371  Apelin signaling pathway
mcc04380  Osteoclast differentiation
mcc04390  Hippo signaling pathway
mcc04520  Adherens junction
mcc04659  Th17 cell differentiation
mcc04926  Relaxin signaling pathway
mcc04933  AGE-RAGE signaling pathway in diabetic complications
mcc05142  Chagas disease
mcc05161  Hepatitis B
mcc05166  Human T-cell leukemia virus 1 infection
mcc05200  Pathways in cancer
mcc05210  Colorectal cancer
mcc05212  Pancreatic cancer
mcc05220  Chronic myeloid leukemia
mcc05225  Hepatocellular carcinoma
mcc05226  Gastric cancer
mcc05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mcc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    714952 (TGFBR1)
   04350 TGF-beta signaling pathway
    714952 (TGFBR1)
   04390 Hippo signaling pathway
    714952 (TGFBR1)
   04371 Apelin signaling pathway
    714952 (TGFBR1)
   04068 FoxO signaling pathway
    714952 (TGFBR1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    714952 (TGFBR1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    714952 (TGFBR1)
  09143 Cell growth and death
   04218 Cellular senescence
    714952 (TGFBR1)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    714952 (TGFBR1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    714952 (TGFBR1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    714952 (TGFBR1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    714952 (TGFBR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    714952 (TGFBR1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    714952 (TGFBR1)
   05212 Pancreatic cancer
    714952 (TGFBR1)
   05225 Hepatocellular carcinoma
    714952 (TGFBR1)
   05226 Gastric cancer
    714952 (TGFBR1)
   05220 Chronic myeloid leukemia
    714952 (TGFBR1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    714952 (TGFBR1)
   05161 Hepatitis B
    714952 (TGFBR1)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    714952 (TGFBR1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    714952 (TGFBR1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    714952 (TGFBR1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mcc01001]
    714952 (TGFBR1)
Enzymes [BR:mcc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     714952 (TGFBR1)
Protein kinases [BR:mcc01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR1 family [OT]
   714952 (TGFBR1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr TGF_beta_GS Activin_recp Pkinase_fungal APH FTA2 Haspin_kinase
Other DBs
NCBI-GeneID: 714952
NCBI-ProteinID: XP_001112621
Ensembl: ENSMMUG00000001304
UniProt: F7H0K3
LinkDB
Position
15:complement(43763472..43812747)
AA seq 503 aa
MEAAAAAPRPRLLLLVLAATAAAAAALLPGATALQCFCHLCTKDNFTCVTDGLCFVSVTE
TTDKVIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTTVKSSPG
LGPVELAAVIAGPVCFVCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDL
IYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREER
SWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVE
GMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDS
ATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGI
HEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGA
ARLTALRIKKTLSQLSQQEGIKM
NT seq 1512 nt   +upstreamnt  +downstreamnt
atggaggcggcggccgctgctccgcgtccccggctgctcctcctcgtgctggcggcgacg
gcggcggcggcggcggcgctgctcccgggggcgacggcattacagtgtttctgccacctc
tgtacaaaagacaattttacttgtgtgacagatgggctctgctttgtctctgtcacagag
accacagacaaagttatacacaacagcatgtgtatagctgaaattgacttaattcctcga
gataggccatttgtatgtgcaccctcttcaaaaactgggtctgtgactacaacatattgc
tgcaatcaggaccattgcaataaaatagaacttccaactactgtaaagtcatcacctggc
cttggtcccgtggaactggcagctgtcattgctggaccagtgtgctttgtctgcatctca
ctcatgttgatggtgtatatctgccacaaccgcactgtcattcaccatcgagtgccaaat
gaagaggacccttcattagatcgtccttttatttcagagggtactacgttgaaagactta
atttatgatatgacaacatcaggttctggctcaggtttaccattgcttgttcagagaaca
attgcgagaactattgtgttacaagaaagcattggcaaaggtcgatttggagaagtgtgg
cgaggaaagtggcggggagaagaagttgctgttaagatattctcttctagagaagaacgt
tcatggttccgtgaggcagagatttatcaaactgtgatgttacgtcatgaaaacatcctg
ggatttatagcagcagacaataaagacaatggcacttggactcagctctggttggtgtca
gattatcatgagcatggatccctttttgattacttaaacagatacacagttactgtggaa
ggaatgataaaacttgctctgtccacagcgagcggtcttgcccatcttcacatggagatt
gttggtactcaaggaaagccagccattgctcacagagatttgaaatcaaagaatatcttg
gtaaagaagaatggaacttgctgtattgcagacttaggactggcagtaagacacgattca
gccacagataccattgatattgctccaaaccacagagtgggaacaaaaaggtacatggcc
cctgaagttcttgatgattccataaatatgaaacattttgaatccttcaaacgtgctgac
atctatgcaatgggcttagtattctgggaaattgctcgacgatgttccattggtggaatt
catgaagattaccagctgccttattatgatcttgtaccttctgacccatcagtggaagaa
atgagaaaagttgtttgtgaacagaagttaaggccaaatatcccaaacagatggcagagc
tgcgaagccttgagagtaatggctaaaattatgagagaatgttggtatgccaacggagca
gctaggcttacagcattgcggattaagaaaacattatcacaactcagtcaacaggaaggc
atcaaaatgtaa

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