KEGG   Macaca mulatta (rhesus monkey): 714983
Entry
714983            CDS       T01028                                 
Symbol
PDE10A
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X7
  KO
K18438  cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35]
Organism
mcc  Macaca mulatta (rhesus monkey)
Pathway
mcc00230  Purine metabolism
mcc01100  Metabolic pathways
mcc04024  cAMP signaling pathway
mcc05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:mcc00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    714983 (PDE10A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    714983 (PDE10A)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    714983 (PDE10A)
Enzymes [BR:mcc01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.17  3',5'-cyclic-nucleotide phosphodiesterase
     714983 (PDE10A)
    3.1.4.35  3',5'-cyclic-GMP phosphodiesterase
     714983 (PDE10A)
SSDB
Motif
Pfam: PDEase_I GAF GAF_2 GAF_3 SpoVT_C HD DUF7334
Other DBs
NCBI-GeneID: 714983
NCBI-ProteinID: XP_001105004
Ensembl: ENSMMUG00000023614
LinkDB
Position
4:4739016..5415945
AA seq 709 aa
MQGVVYELNSYIEQRLDTGGDNQLLLYELSSIIKIATKADGFALYFLGECNNSLCIFTPP
GIKEGKPRLIPAGPITQGTTISAYVAKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLC
LPIVTAIGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELN
DFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIGEEK
EGKPVFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCM
PIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRV
TMEKLSYHSICTAEEWQGLMRFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGT
SCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHALFTDLERKGLLIAC
LCHDLDHRGFSNTYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYE
QVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTK
LWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTT
LTQILPPTEPLLKACRDNLNQWEKVIRGEETATWISSPSVAQKTAASED
NT seq 2130 nt   +upstreamnt  +downstreamnt
atgcagggagttgtatatgaactaaacagctatatagaacaacggttggacacaggagga
gacaaccagctactcctctatgaactgagcagcatcatcaaaatagccacaaaagctgat
ggatttgcattgtatttccttggagagtgcaataatagcctgtgcatattcacaccacct
gggataaaggaaggaaaaccccgcctcatccctgctgggcccatcactcagggcaccacc
atctctgcttatgtggccaagtccaggaagacattgctagtagaagacatccttggagat
gagcgatttccaagaggtactggactggaatcagggactcgtatccagtctgttctttgc
ttaccaattgtcactgcaattggtgacttgattggtattcttgagctgtatcggcactgg
ggcaaagaagccttctgtcttagtcaccaggaggttgcaacagcaaatcttgcctgggct
tcagtagcaatacatcaggtgcaggtatgcagaggccttgccaaacagactgaattgaat
gactttctactcgacgtatcaaaaacatattttgataacatagttgcaatagattctcta
cttgaacacataatgatatatgcaaaaaacctggtgaatgccgaccgttgtgcacttttc
caggtagaccataagaacaaggagttatattcagacctttttgatattggagaggaaaag
gaaggaaaacccgtcttcaagaagaccaaagagataagattttcaattgagaaaggaatt
gctggccaagtagcaagaacaggggaagtcctgaacattccagatgcctatgcagaccca
cgctttaacagagaagtagacttgtacacaggctacaccacgcggaacatcctgtgcatg
cccatcgtcagccgaggcagcgtgataggtgtggtgcagatggtcaacaaaatcagtggc
agtgccttctctaaaaccgatgaaaacaacttcaaaatgtttgccgtcttttgtgcttta
gccttacactgtgctaatatgtatcatagaattcgccactcagagtgcatttaccgggta
acaatggaaaagctgtcctaccatagcatttgtactgcagaagagtggcaaggcctcatg
cgatttacccttcctgtgcgtctctgcaaagaaattgaattattccactttgacattggt
ccttttgaaaacatgtggcctggaatttttgtctacatggttcatcggtcctgtgggaca
tcctgctttgagctcgaaaagttgtgtcgttttattatgtctgtgaagaagaactatcgg
cgggttccttatcacaactggaagcatgcggtcactgtagcacactgcatgtacgccata
cttcagaacaaccacgcgcttttcacagaccttgagcgcaaaggactgctgatcgcgtgt
ctgtgtcatgacctagaccacagaggcttcagtaacacctacctgcagaagttcgaccac
cctctagcagctctctactccacttccaccatggagcagcaccacttctcccagaccgtg
tccatcctccagctggaagggcacaatatcttctccactctgagctccagtgaatacgag
caggtgcttgagatcatccgcaaagccatcattgccacagaccttgctttatactttgga
aacaggaaacagttggaagagatgtaccagacgggatcgctaaaccttaataatcaatca
cacagagaccgtgtaattggtttgatgatgactgcctgtgacctttgttctgtgacaaaa
ctgtggcccgttacaaaattgacggcaaatgatatatatgcagaattctgggctgagggt
gatgaaatgaagaaattgggaatacagcctattcctatgatggacagagacaagaaggat
gaagtcccccaaggccagcttgggttctacaatgccgtagccattccctgctatacaacc
cttacccagatcctccctcccacggagcctctccttaaagcatgcagggataatctcaat
cagtgggagaaggttattcgaggggaggagactgcaacctggatttcatccccgtccgtg
gctcagaagacagctgcatctgaagattga

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