Macaca mulatta (rhesus monkey): 715422
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Entry
715422 CDS
T01028
Symbol
MYLK
Name
(RefSeq) myosin light chain kinase, smooth muscle isoform X1
KO
K00907
myosin-light-chain kinase [EC:
2.7.11.18
]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc04020
Calcium signaling pathway
mcc04022
cGMP-PKG signaling pathway
mcc04270
Vascular smooth muscle contraction
mcc04371
Apelin signaling pathway
mcc04510
Focal adhesion
mcc04611
Platelet activation
mcc04810
Regulation of actin cytoskeleton
mcc04921
Oxytocin signaling pathway
mcc04971
Gastric acid secretion
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
715422 (MYLK)
04020 Calcium signaling pathway
715422 (MYLK)
04022 cGMP-PKG signaling pathway
715422 (MYLK)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
715422 (MYLK)
09142 Cell motility
04810 Regulation of actin cytoskeleton
715422 (MYLK)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
715422 (MYLK)
09152 Endocrine system
04921 Oxytocin signaling pathway
715422 (MYLK)
09153 Circulatory system
04270 Vascular smooth muscle contraction
715422 (MYLK)
09154 Digestive system
04971 Gastric acid secretion
715422 (MYLK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mcc01001
]
715422 (MYLK)
Enzymes [BR:
mcc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.18 myosin-light-chain kinase
715422 (MYLK)
Protein kinases [BR:
mcc01001
]
Serine/threonine kinases: CAMK group
MLCK family
715422 (MYLK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
I-set
Ig_3
ig
Ig_2
Pkinase
23ISL
V-set
PK_Tyr_Ser-Thr
C2-set_2
fn3
Ig_4
Ig_DSCAM-DSCAML_C
Invasin_D3
Kinase-like
Kdo
Ig_J_second
Pur_ac_phosph_N
AvrM_N
Motif
Other DBs
NCBI-GeneID:
715422
NCBI-ProteinID:
XP_001113525
Ensembl:
ENSMMUG00000014818
UniProt:
F6VWL8
LinkDB
All DBs
Position
2:152480878..152701002
Genome browser
AA seq
1914 aa
AA seq
DB search
MGDVKLVASSHISKTSLSVAPSRVGSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP
EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE
LTVEGSFAKQLGQPVVSKTLGDRFSASAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF
SCKITGRPQPQVTWLKGNVPLQPSARVSMSEKNGMQVLEIHGVNQDDMGVYTCLVVNGSG
KASMSAELSIQGLDSANRSFGRETKATNSYVRREVTNVISKELKLNSLEAAAESKNCCSP
QRGGSPAWAANSQPQPPRESKLESCKDSPRTAPQTPVLQTTSSSITLQAARVQLEPRAPG
LGALSPSGEERKRPAAPRPATFPTRQPGLGSQDVVSKAATRIIPMEGQKDSALPKFESKP
QSQEVRENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLRARTR
DSGTYSCTASNARGQVSCSWTLQVERLAVMEVAPSFSSVLKDCTVIEGQDFVLQCSVRGT
PVPQITWLLNGQPIQYAHSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSARVTV
HEKKSSGKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG
NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ
PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALSKDTGHYEVLQNEDVFTLV
LKKVQPWHAGRYEILLKNRVGECSCQVSLMLQNSPAGALPRGREPASCEGLCGGGVGADG
GGSDRYGTLRPGWPARGQGWPEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL
LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK
GTPKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS
GPLKPMGNAKPAETLKPMGNAKPAETLKPMGNTKPAETLKSASKEELKKDVKNDVNCKRG
HAGTTDNEKRSESQGTAPVFKEKLQDVRVAEGEKLLLQCQVSSDPPATVTWTLNGKTLKT
TKFIVLSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE
MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK
VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ
AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE
LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD
DEKEPEVDYRTVTINTEQKVSDVYDIEERLGSGKFGQVFRLVEKKTRKIWAGKFFKAYSA
KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER
ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV
LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF
DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM
ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV
AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD
EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
NT seq
5745 nt
NT seq
+upstream
nt +downstream
nt
atgggggatgtgaagctggttgcctcgtcacacatttccaaaacctccctcagcgtggct
ccctcaagagttggctccatgcccctgacagaggcccctgctttcattttgccccctcgg
aacctctgcatcaaagaaggagccaccgccaagttcgaagggcgggtccggggttaccca
gagccccaggtgacgtggcacagaaacgggcaacccatcaccagtgggggccgctttctg
ctggactgcggcatccgggggaccttcagcctagtgattcatgctgtccacgaggaggac
aggggaaagtatacctgtgaagccaccaatggcagtggtgctcgccaggtgacagtggag
ttgacagtagaaggaagttttgcaaagcaacttggtcaacctgttgtttccaaaactttg
ggggatagattttcagcttcagcagtggagacccgtcctagcatctggggggagtgccca
ccaaagtttgctaccaagctgggccgagttgtggtcaaagaaggacagatgggacgattc
tcctgcaagatcactggccggccccaaccgcaggtcacctggctcaagggaaatgttcca
ctgcagccgagtgcccgtgtgtctatgtctgagaagaacgggatgcaggttctggaaatc
catggagtcaaccaagatgacatgggagtgtacacgtgcctggtggtgaacgggtcaggc
aaggcctcgatgtcagctgaactttccatccaaggtttggacagtgccaataggtcattt
gggagagaaacaaaagccaccaattcctacgtcaggagggaggtgaccaatgtaatctca
aaggagttgaaactgaacagtctggaggctgcagccgaaagcaagaactgctgcagcccc
cagagaggtggttccccagcctgggctgcaaacagccagcctcagcccccaagggagtcc
aagctggagtcatgcaaggactcgcccagaacggccccgcagaccccggtccttcagacg
acttccagctccatcaccctgcaggccgcaagagttcagctggaaccaagagcaccaggc
ctgggggccctatcgccttctggagaagagaggaagaggccagctgcaccccgtccagcc
accttccccaccaggcagcctggcctggggagccaagacgttgtgagcaaggctgctacc
aggataatccccatggagggccagaaggattcagcactccccaaatttgagagcaagccc
caaagccaggaggtcagggaaaatcaaactgtcaagttcagatgtgaagtttcagggatt
ccaaagcctgaagtggcctggttcctggaaggcacccccgtgaggagacaggagggcagc
attgaggtttatgaagatgctggctcccattacctctgcctgctgagagcccggaccagg
gacagtgggacatacagctgcactgcttccaacgcccgaggccaggtgtcctgtagctgg
accctccaagtggaaaggcttgctgtgatggaggtggccccctccttctccagtgtcctg
aaggactgcactgtcattgagggtcaggattttgtgctgcagtgctccgtacgggggact
ccagtgccccagatcacttggctgctgaatggacagcccatccagtacgctcactccacc
tgcgaggctggcgtggctgagctccacatccaggatgccctgccagaggaccatggcacc
tacacctgcctggctgagaatgccttggggcaggtgtcctgcagcgcccgggtcaccgtc
catgaaaagaagagtagcgggaagagcgagtaccttctgcctgtggcccccagcaagccc
actgcccccatcttcctgcagggcctctctgatctcaaagtcatggatggaagccaggtc
actatgacagtccaagtgtcagggaatccaccccctgaggtcatctggctgcacaatggg
aacgagatccaagagtcagaggacttccactttgaacagagaggcactcagcacagcctt
tgtatccaggaagtgttcccggaggacacgggcacatacacctgcgaggcctggaacagc
gctggagaggtccgcacccaggccgtgctcacggtacaagagcctcacgatggcacccag
ccctggttcatcagtaagcctcgctcggtgacagcctccctgggccagagtgtcctcatc
tcctgcgccatagctggtgacccctttcctactgtgcactggctccgagatggcaaagcc
ctctccaaagacactggccactacgaggtgcttcagaatgaggacgtgttcaccctggtt
ctaaagaaggtgcagccctggcatgccggccggtatgagatcctgctcaagaaccgggtt
ggtgaatgcagttgccaggtgtcactgatgctacagaacagccctgccggagcccttcca
cgggggagggagcctgccagctgtgagggcctctgtggtggaggagttggtgctgatggt
ggtggtagtgaccgctatgggaccctgaggcctggctggccagcaagagggcagggttgg
ccagaggaggaagacggcgaggacgtgcgaggggtgctgaagaggcgcgtggagacgagg
cagcacaccgaggaggcgatccgccagcaggaggtggagcagctggacttccgagacctc
ctggggaagaaggtgagtaccaagaccctatcggaagacgacctgaaggagatcccagcc
gagcagatggatttccgtgccaacctgcagcggcaagtgaagccaaagactgtgtccgag
gaagagaggaaggtgcacagcccccagcaggtcgatttccgctctgtcctggccaagaag
gggactcccaagacccctgtgcctgagaaggtgccaccaccgaaacctgccaccccggat
tttcgctcagtgctcggtggcaagaagaaattaccagcggagaatggtagcagcagtgct
gagaccctgaatgccaaggccgtggaaagttccaagcccctgagcaatgcacagccttca
gggcccttgaaacccatgggcaacgccaagcctgctgagaccctgaagcccatgggcaac
gccaagcctgctgagaccctgaagcccatgggcaacaccaagcctgctgagaccctgaaa
tccgctagcaaagaagaactcaagaaagatgttaagaatgatgtgaattgcaagagaggc
catgcagggaccacagataatgaaaaaagatcagagagccaggggacagccccagtcttc
aaggagaagctgcaagatgttcgtgtggcagagggcgagaagctgctgctccagtgccag
gtgtcttctgaccccccagccaccgtcacctggacactgaatggaaagaccctcaagacc
accaagttcatcgtcctctcccaggaaggctcactctgctccgtctccatcgagaaggca
ctgcctgaggacagaggcttgtacaagtgtgtagccaagaatgatgctggccaggctgag
tgctcctgccaagtcaccgtggacgatgccccggccagtgagaacaccaaggccccagag
atgaaatcccggaggcccaagagctctcttcctcccgtgctaggaactgagagtgatgca
actgtgaaaaagaaacctgcccccaagacacctccgaaggcagcaatgccccctcagatc
atccagttccctgaggaccagaaggtacgcgccggagagtcagtggagctgtttggtaaa
gtgacaggcacccagcccatcacctgtacctggatgaagttccgaaagcagatccaggag
agcgagcacatgaaggtggagaacagcgagaatggcagcaagctcaccatcctggccgca
cgccaggagcactgcggctgctacacactgctggtggagaacaagctgggcagcaggcag
gcccaggtcaacctcactgtcgtggataagccagaccccccagctggcacaccttgtgcc
tctgacattcggagctcctcactgaccctgtcctggtacggctcctcgtacgatgggggc
agtgccgtgcagtcctacagcatcgagatctgggactcagccaacaagacgtggaaggaa
ctagccacatgccgcagcacctctttcaacgttcaggacctgctgcctgaccatgagtat
aagttccgtgtacgtgcaatcaacgtgtatggaaccagtgagccaagccaggagtctgaa
ctcacaacggtaggagagaaacctgaagagccaaaggatgaagtggaggtttcagacgat
gatgagaaggagcctgaggttgattatcggacggtgacaatcaatactgaacaaaaagta
tctgacgtctacgacatcgaagagagattaggatctgggaaatttggacaggtctttcga
cttgtagaaaagaaaactcgaaaaatctgggcagggaaattcttcaaggcatattcagca
aaagagaaagagaatatccggcaggagatcagcatcatgaactgcctccaccaccccaag
ctcgtccagtgtgtggatgccttcgaagaaaaggccaacatcgtcatggtcctggagatc
gtgtcaggaggtgagctgtttgagcgcatcattgacgaggacttcgagctgacggagcgc
gagtgcatcaagtacatgcggcagatctcggagggggtggagtacatccacaagcagggc
atcgtgcacctggacctcaagccggagaacatcatgtgtgtcaacaagacgggcaccagg
atcaagctcatcgactttggtctggccaggaggctggagaatgcggggtccctgaaggtc
ctctttggcaccccggagtttgtggctcctgaagtgatcaactatgagcccatcggctat
gccacagacatgtggagcatcggggtcatctgctacatcctagtcagtggcctttccccc
ttcatgggagacaacgataatgaaaccttggccaacgttacctcagccacctgggatttc
gacgacgaggcattcgatgagatctccgacgatgccaaggatttcatcagcaatctgctg
aagaaagatatgaaaaaccgcctggactgcacacagtgccttcagcatccatggctaatg
aaagataccaagaacatggaggccaagaaactctccaaggaccggatgaagaagtacatg
gcaagaaggaaatggcagaaaacgggcaatgctgtgagagccattggaagactgtcctct
atggcaatgatctcagggctcagtggcaggaaatcctcaacagggtcaccaaccagcccg
ctcaatgcagaaaaactagaatctgaagaagatgtgtcccaagctttccttgaggctgtt
gctgaggaaaagcctcatgtaaaaccctatttctctaagaccattcgtgatttagaagtt
gtggagggaagtgctgctagatttgactgcaagattgaaggatacccggaccccgaggtt
gtctggttcaaagatgaccagtcaatcagggagtcccgccacttccagatagactacgat
gaggacgggaactgctctttaattattagtgatgtttgtggggatgatgatgccaagtac
acctgcaaagctgtcaacagtcttggagaagccacctgcacagcagagctcattgtggaa
acgatggaggaaggtgaaggggaaggggaagaggaagaagagtga
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integrated database retrieval system
