Macaca mulatta (rhesus monkey): 717751
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Entry
717751 CDS
T01028
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
mcc
Macaca mulatta (rhesus monkey)
Pathway
mcc04140
Autophagy - animal
mcc04141
Protein processing in endoplasmic reticulum
mcc04210
Apoptosis
mcc04932
Non-alcoholic fatty liver disease
mcc05010
Alzheimer disease
mcc05012
Parkinson disease
mcc05014
Amyotrophic lateral sclerosis
mcc05016
Huntington disease
mcc05017
Spinocerebellar ataxia
mcc05022
Pathways of neurodegeneration - multiple diseases
mcc05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mcc00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
717751 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
717751 (ERN1)
09143 Cell growth and death
04210 Apoptosis
717751 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
717751 (ERN1)
05012 Parkinson disease
717751 (ERN1)
05014 Amyotrophic lateral sclerosis
717751 (ERN1)
05016 Huntington disease
717751 (ERN1)
05017 Spinocerebellar ataxia
717751 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
717751 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
717751 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
717751 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mcc01001
]
717751 (ERN1)
Enzymes [BR:
mcc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
717751 (ERN1)
Protein kinases [BR:
mcc01001
]
Serine/threonine kinases: Other
IRE family
717751 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
Beta-prop_ACSF4
PQQ_2
Pkinase_fungal
Kdo
APH
CytochromB561_N
Motif
Other DBs
NCBI-GeneID:
717751
NCBI-ProteinID:
XP_001109583
Ensembl:
ENSMMUG00000015185
UniProt:
F6WBI3
LinkDB
All DBs
Position
16:complement(60594802..60686360)
Genome browser
AA seq
978 aa
AA seq
DB search
MPARRLLLLLLTLLLPGLGIFGSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKED
PVLQVPTHVEEPAFLPDPNDGSLYTLGSKNNEGLTKLPFTIPELVQASPCRSSDGILYMG
KKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATY
FDYAASLPEDDMDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRK
VMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSM
VHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTELKFDSGLKSKNKLNYLRNYW
LLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSENAPTTVS
RDVEEKPAHAPARPEAPVDSMLKDVATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQF
QKELEKIQLLQQQQQQLPFHPPGDTAQDGELLDTSGPYSESSGTSSPNTSPRASNHSLCS
GSSASKAGSSPSLEQDDGDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVK
RILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFA
HLGLEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILISMPNAHGKIKAMISDFGLCKKLA
AGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSL
QRQANILLGACSLECLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQL
QFFQDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRD
LLRAMRNKKHHYRELPAEVRETLGSLPDDFVCYFTSRFPHLLAHTYRAMELCSHERLFQP
YYFHRPPEPQPPVTPDAL
NT seq
2937 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggcggctgctgctgctgctgctgacgctgctgctgcccggcctcgggatt
tttggaagtaccagcacagtgacgcttcctgaaaccttgttgtttgtgtcaacgctggat
ggaagtttacatgctgtcagcaagaggacaggctcaatcaaatggactttaaaagaagat
ccagtcctgcaggtcccaacgcatgtggaagagcctgcctttctcccagatcctaatgat
ggcagcctgtatacgcttggaagcaagaataatgaaggcctgacgaaacttccttttacc
atcccagaattggtgcaggcatccccgtgccgaagttcagatggaatcctctacatgggt
aaaaagcaggacatctggtatgttattgacctcctgactggggagaagcagcagaccttg
tcatcagcctttgcagatagtctctgcccatcaacctctcttctgtatcttgggcgaaca
gaatacaccatcaccatgtacgacaccaaaacgcgagagctccggtggaatgccacctac
tttgactacgcagcctcgctgcctgaggacgacatggactacaagatgtcccactttgtg
tccaatggtgatgggctggtggtgaccgtggacagtgaatctggggatgtcctgtggatc
caaaactacgcctcccctgtggtggccttttatgtctggcagcgggagggtctgaggaag
gtgatgcacatcaatgtcgccgtggagaccctgcgctatctgaccttcatgtctggggag
gtggggcgcatcaccaagtggaagtacccgttccccaaggagacagaggccaagagcaag
ctgacgcccactctgtatgttgggaaatactctaccagcctctatgcctctccctcaatg
gtacacgagggagttgctgtcgtgccccgcggcagcacacttcctttgctggaagggccc
cagactgatggcgtcaccattggggacaagggggagtgtgtgatcacgcccagcacagag
ctcaagtttgactccggactcaaaagcaagaacaagctcaactacttgaggaattactgg
cttctgataggccaccatgaaaccccactgtctgcatctaccaagatgctggagagattt
cccaacaatctgcccaaacatcgggaaaatgtgattcctgctgattcagagaaaaagagc
tttgaggaagttatcaacctggttgaccagacttcagaaaacgcacctaccaccgtgtct
cgggatgtggaggagaagcccgcccatgcccccgcccggcccgaggcccccgtggactcc
atgctcaaggacgtggccaccatcatcctgagcaccttcctgctgattggctgggtggcc
ttcatcatcacctaccccctgagcatgcatcagcagcagcagctccagcaccagcagttc
cagaaggaactggagaagattcagctcctgcagcagcagcagcagcagctgcccttccac
ccacctggagacacggctcaggacggcgagcttctggacacatctggcccatactcagag
agctcgggcaccagcagccccaacacgtcccccagggcctccaaccactcgctctgctcc
ggcagctctgcctccaaggctggcagcagcccctccctggagcaagacgacggagatgag
gaaaccagcatggtgatagttgggaaaatttccttctgtcccaaggacgtcctgggccat
ggagctgagggcacaattgtgtaccggggcatgtttgacaaccgtgatgtggccgtgaag
aggatcctccccgagtgttttagcttcgcagaccgtgaggtccagctgttgcgagaatca
gatgagcacccgaacgtgatccgctacttctgcacggagaaggaccggcaattccagtac
attgccatcgagctgtgtgcagccaccctgcaagagtatgtggagcagaaggactttgcg
catctcggcctggagcccatcaccttgctgcagcagaccacctcgggcctggcccacctt
cactccctcaacatcgttcacagagacctaaagccccacaacattctcatatccatgccc
aatgcacatggcaagatcaaggccatgatctctgactttggcctgtgcaagaagctggca
gcgggcaggcacagcttcagccgccgatctggggtgcctggcacagaaggctggatcgct
ccagagatgctgagcgaagactgtaaggagaaccctacctacacggtggacatcttttct
gcaggctgcgtcttttactacgtgatctctgagggcagccacccttttggcaagtccctg
cagcggcaggccaacatcctcctgggtgcctgcagcctcgagtgcttgcacccagagaag
cacgaagacgtcattgcacgtgaattgatagagaagatgattgcgatggatcctcagaaa
cgcccctcagcgaagcacgtgctgaaacacccgttcttctggagcctagagaagcagctc
cagttcttccaggacgtgagcgacagaatagaaaaggaatccctggatggcccgattgtg
aagcagttagagagaggcgggagagccgtggtgaagatggactggcgggagaacatcacc
gtccccctccagacagacctgcgtaaattcaggacctataaaggtggttctgtcagagat
ctcctccgagccatgagaaataagaagcaccactaccgggaactgcctgcggaggtgcgg
gagacgctggggtccctccctgacgacttcgtgtgctacttcacgtctcgcttcccccac
ctcctcgcacacacctaccgggccatggagctgtgcagccacgagagactcttccagccc
tactacttccacaggcccccagagccccagcccccagtgactccagacgccctctga
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