Macaca mulatta (rhesus monkey): 718412 Help Entry 718412            CDS       T01028                                  Symbol PRKCA Name (RefSeq) protein kinase C alpha type   KO K02677   classical protein kinase C alpha type [EC:2.7.11.13] Organism mcc  Macaca mulatta (rhesus monkey) Pathway mcc01521   EGFR tyrosine kinase inhibitor resistance mcc04010   MAPK signaling pathway mcc04012   ErbB signaling pathway mcc04014   Ras signaling pathway mcc04015   Rap1 signaling pathway mcc04020   Calcium signaling pathway mcc04066   HIF-1 signaling pathway mcc04070   Phosphatidylinositol signaling system mcc04071   Sphingolipid signaling pathway mcc04072   Phospholipase D signaling pathway mcc04082   Neuroactive ligand signaling mcc04150   mTOR signaling pathway mcc04151   PI3K-Akt signaling pathway mcc04261   Adrenergic signaling in cardiomyocytes mcc04270   Vascular smooth muscle contraction mcc04310   Wnt signaling pathway mcc04360   Axon guidance mcc04370   VEGF signaling pathway mcc04510   Focal adhesion mcc04540   Gap junction mcc04613   Neutrophil extracellular trap formation mcc04650   Natural killer cell mediated cytotoxicity mcc04664   Fc epsilon RI signaling pathway mcc04666   Fc gamma R-mediated phagocytosis mcc04670   Leukocyte transendothelial migration mcc04713   Circadian entrainment mcc04720   Long-term potentiation mcc04723   Retrograde endocannabinoid signaling mcc04724   Glutamatergic synapse mcc04725   Cholinergic synapse mcc04726   Serotonergic synapse mcc04727   GABAergic synapse mcc04728   Dopaminergic synapse mcc04730   Long-term depression mcc04750   Inflammatory mediator regulation of TRP channels mcc04911   Insulin secretion mcc04912   GnRH signaling pathway mcc04916   Melanogenesis mcc04918   Thyroid hormone synthesis mcc04919   Thyroid hormone signaling pathway mcc04921   Oxytocin signaling pathway mcc04925   Aldosterone synthesis and secretion mcc04926   Relaxin signaling pathway mcc04928   Parathyroid hormone synthesis, secretion and action mcc04929   GnRH secretion mcc04933   AGE-RAGE signaling pathway in diabetic complications mcc04935   Growth hormone synthesis, secretion and action mcc04960   Aldosterone-regulated sodium reabsorption mcc04961   Endocrine and other factor-regulated calcium reabsorption mcc04970   Salivary secretion mcc04971   Gastric acid secretion mcc04972   Pancreatic secretion mcc05017   Spinocerebellar ataxia mcc05022   Pathways of neurodegeneration - multiple diseases mcc05031   Amphetamine addiction mcc05032   Morphine addiction mcc05143   African trypanosomiasis mcc05146   Amoebiasis mcc05161   Hepatitis B mcc05163   Human cytomegalovirus infection mcc05164   Influenza A mcc05170   Human immunodeficiency virus 1 infection mcc05171   Coronavirus disease - COVID-19 mcc05200   Pathways in cancer mcc05205   Proteoglycans in cancer mcc05206   MicroRNAs in cancer mcc05207   Chemical carcinogenesis - receptor activation mcc05214   Glioma mcc05223   Non-small cell lung cancer mcc05225   Hepatocellular carcinoma mcc05231   Choline metabolism in cancer mcc05415   Diabetic cardiomyopathy mcc05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mcc00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     718412 (PRKCA)    04012 ErbB signaling pathway     718412 (PRKCA)    04014 Ras signaling pathway     718412 (PRKCA)    04015 Rap1 signaling pathway     718412 (PRKCA)    04310 Wnt signaling pathway     718412 (PRKCA)    04370 VEGF signaling pathway     718412 (PRKCA)    04066 HIF-1 signaling pathway     718412 (PRKCA)    04020 Calcium signaling pathway     718412 (PRKCA)    04070 Phosphatidylinositol signaling system     718412 (PRKCA)    04072 Phospholipase D signaling pathway     718412 (PRKCA)    04071 Sphingolipid signaling pathway     718412 (PRKCA)    04151 PI3K-Akt signaling pathway     718412 (PRKCA)    04150 mTOR signaling pathway     718412 (PRKCA)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     718412 (PRKCA)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     718412 (PRKCA)    04540 Gap junction     718412 (PRKCA)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     718412 (PRKCA)    04650 Natural killer cell mediated cytotoxicity     718412 (PRKCA)    04664 Fc epsilon RI signaling pathway     718412 (PRKCA)    04666 Fc gamma R-mediated phagocytosis     718412 (PRKCA)    04670 Leukocyte transendothelial migration     718412 (PRKCA)   09152 Endocrine system    04911 Insulin secretion     718412 (PRKCA)    04929 GnRH secretion     718412 (PRKCA)    04912 GnRH signaling pathway     718412 (PRKCA)    04921 Oxytocin signaling pathway     718412 (PRKCA)    04926 Relaxin signaling pathway     718412 (PRKCA)    04935 Growth hormone synthesis, secretion and action     718412 (PRKCA)    04918 Thyroid hormone synthesis     718412 (PRKCA)    04919 Thyroid hormone signaling pathway     718412 (PRKCA)    04928 Parathyroid hormone synthesis, secretion and action     718412 (PRKCA)    04916 Melanogenesis     718412 (PRKCA)    04925 Aldosterone synthesis and secretion     718412 (PRKCA)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     718412 (PRKCA)    04270 Vascular smooth muscle contraction     718412 (PRKCA)   09154 Digestive system    04970 Salivary secretion     718412 (PRKCA)    04971 Gastric acid secretion     718412 (PRKCA)    04972 Pancreatic secretion     718412 (PRKCA)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     718412 (PRKCA)    04961 Endocrine and other factor-regulated calcium reabsorption     718412 (PRKCA)   09156 Nervous system    04724 Glutamatergic synapse     718412 (PRKCA)    04727 GABAergic synapse     718412 (PRKCA)    04725 Cholinergic synapse     718412 (PRKCA)    04728 Dopaminergic synapse     718412 (PRKCA)    04726 Serotonergic synapse     718412 (PRKCA)    04720 Long-term potentiation     718412 (PRKCA)    04730 Long-term depression     718412 (PRKCA)    04723 Retrograde endocannabinoid signaling     718412 (PRKCA)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     718412 (PRKCA)   09158 Development and regeneration    04360 Axon guidance     718412 (PRKCA)   09159 Environmental adaptation    04713 Circadian entrainment     718412 (PRKCA)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     718412 (PRKCA)    05206 MicroRNAs in cancer     718412 (PRKCA)    05205 Proteoglycans in cancer     718412 (PRKCA)    05207 Chemical carcinogenesis - receptor activation     718412 (PRKCA)    05231 Choline metabolism in cancer     718412 (PRKCA)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     718412 (PRKCA)    05214 Glioma     718412 (PRKCA)    05223 Non-small cell lung cancer     718412 (PRKCA)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     718412 (PRKCA)    05161 Hepatitis B     718412 (PRKCA)    05171 Coronavirus disease - COVID-19     718412 (PRKCA)    05164 Influenza A     718412 (PRKCA)    05163 Human cytomegalovirus infection     718412 (PRKCA)   09174 Infectious disease: parasitic    05146 Amoebiasis     718412 (PRKCA)    05143 African trypanosomiasis     718412 (PRKCA)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     718412 (PRKCA)    05022 Pathways of neurodegeneration - multiple diseases     718412 (PRKCA)   09165 Substance dependence    05031 Amphetamine addiction     718412 (PRKCA)    05032 Morphine addiction     718412 (PRKCA)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     718412 (PRKCA)    05415 Diabetic cardiomyopathy     718412 (PRKCA)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     718412 (PRKCA)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     718412 (PRKCA)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mcc01001]     718412 (PRKCA)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mcc04131]     718412 (PRKCA) Enzymes [BR:mcc01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      718412 (PRKCA) Protein kinases [BR:mcc01001]  Serine/threonine kinases: AGC group   PKC family [OT]    718412 (PRKCA) Membrane trafficking [BR:mcc04131]  Endocytosis   Lipid raft mediated endocytosis    Caveolin-mediated endocytosis     718412 (PRKCA) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C C1_2 ABC1 Motif Other DBs NCBI-GeneID:  718412 NCBI-ProteinID:  NP_001247662 Ensembl:  ENSMMUG00000018378 UniProt:  H9EMT3 LinkDB All DBs Position 16:62679282..63190313 Genome browser AA seq 672 aa AA seqDB search MADVFPANDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVADEKLHVTVRDA KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNME LRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKG TEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYV NGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIA DFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDG EDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGPEGERDVREHAFFRRI DWEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVN PQFVHPILQSAV NT seq 2019 nt NT seq  +upstreamnt  +downstreamnt atggctgacgttttcccggccaacgactccacggcgtctcaggacgtggccaaccgcttc gcccgcaaaggggcgctgaggcagaagaacgtgcacgaggtgaaggaccacaaattcatc gcgcgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctgggggttt gggaaacagggcttccagtgccaagtttgctgttttgtggtccacaagaggtgccatgaa tttgttactttttcttgtccgggtgcagataagggacccgacactgatgaccccaggagc aagcacaagttcaaaatccacacttacggaagccccaccttctgcgatcactgtgggtcc ctgctgtatggacttatccaccaagggatgaaatgtgacacctgcgatatgaacgttcac aagcaatgcgtcatcaatgtccccagcctctgcggaatggatcacacagagaagaggggg cggatttacctaaaggctgaggttgctgatgaaaagctccatgtcacagtacgagatgca aaaaatctaatccctatggatccaaacgggctttcagatccttatgtgaagctgaaactt attcctgatcccaagaatgaaagcaaacaaaaaaccaaaaccatccgctccacactaaat ccccagtggaatgagtcctttacattcaaactgaaaccttcagacaaagaccgacgactg tctgtagaaatctgggactgggatcgaacaacaaggaatgacttcatgggatccctttcc tttggggtttcggaactaatgaagatgccagccagtggatggtacaagttgcttaaccaa gaagaaggtgagtactacaatgtacccattccagaaggggacgaagaaggaaacatggaa ctcaggcagaaattcgagaaagccaagcttggccctgctggcaacaaagtcatcagtccc tctgaagacaggaaacagccttccaacaacctggaccgagtgaaactcaccgacttcaat ttcctcatggtgctggggaaggggagttttggaaaggtgatgcttgccgacaggaagggc acagaagaactgtatgcaatcaaaatcctgaagaaggatgtggtgattcaggacgacgac gtggagtgcaccatggtagaaaaacgagtcttggccctgcttgacaaacccccgttcttg acgcagctgcactcctgcttccagacagtggatcggctgtacttcgtcatggaatatgtc aacggtggggacctcatgtaccacattcagcaagtaggaaaatttaaggaaccacaagca gtattctatgcggcagagatttccatcggattgttctttcttcataaaagaggaatcatt tatagggatctgaagttagataacgtcatgttggattcagaaggacatatcaaaattgct gactttgggatgtgcaaggaacatatgatggatggagtcacgaccaggaccttctgtggg actccagattacatcgccccagagattatcgcttatcagccatatggaaaatctgtggac tggtgggcctatggcgtcctgttgtatgaaatgcttgccgggcagcctccatttgatggt gaagatgaagacgagctgtttcagtctatcatggagcacaacgtttcctatccaaaatcc ttgtccaaggaggctgtttccatctgcaaaggactaatgaccaaacacccagccaagcgg ctgggctgcgggcctgagggggagagggacgtgagagaacatgctttcttccggaggatc gactgggaaaaactggagaacagggagatccagccaccgttcaagcccaaagtgtgcggc aaaggagcagaaaactttgacaagttcttcacacgagggcagcccgtcttaacgccgcct gatcagctggttatcgctaacatagaccagtctgattttgaagggttctcgtatgtcaac ccccagtttgtgcaccccatcttacagagtgcggtatga

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