Mycobacterium canettii CIPT 140010059: MCAN_25361
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Entry
MCAN_25361 CDS
T01585
Symbol
pdhA
Name
(GenBank) putative pyruvate dehydrogenase E1 component (alpha subunit) PDHA (pyruvate decarboxylase) (pyruvate dehydrogenase) (pyruvic dehydrogenase)
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
mce
Mycobacterium canettii CIPT 140010059
Pathway
mce00280
Valine, leucine and isoleucine degradation
mce00640
Propanoate metabolism
mce00785
Lipoic acid metabolism
mce01100
Metabolic pathways
mce01110
Biosynthesis of secondary metabolites
mce01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
mce00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
MCAN_25361 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
MCAN_25361 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MCAN_25361 (pdhA)
Enzymes [BR:
mce01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
MCAN_25361 (pdhA)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Transketolase_N
MCD
Motif
Other DBs
NCBI-ProteinID:
CCC44867
UniProt:
A0AB72XPS9
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Position
complement(2879054..2880157)
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AA seq
367 aa
AA seq
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MGEGSRRPSGMLMSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTE
FVNLQRQGELALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAW
RGTWHGGLQFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVH
EALNFAAVFTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACY
AVMAEAAARARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYL
QDQGLWSQRLEEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLR
AELARTD
NT seq
1104 nt
NT seq
+upstream
nt +downstream
nt
atgggggagggttctcggaggccatctgggatgttgatgtctgtcgatcttgagccggtg
caactcgtcggcccggacggtacgccgacggccgaacgccgctaccaccgtgaccttcct
gaggaaacgctgcgttggctctacgagatgatggtggtcacccgcgagctggataccgaa
ttcgtcaatctgcagcgccagggggagctggcgttgtacacgccctgtcgcgggcaggaa
gccgcgcaggtgggtgcggcggcttgcctacgcaaaaccgactggttgttcccccaatac
cgagaattgggcgtctacctagtgcgtggcatcccgcctggacatgttggggtcgcgtgg
cgtggaacctggcacggcgggctgcaattcaccacgaagtgctgtgcaccgatgtcggtt
cccatcggcacccagaccttgcacgcggtgggcgcggcgatggccgcgcaacgcctggac
gaggactccgtgacggtggcctttctgggcgacggcgccaccagcgagggcgacgtacat
gaggcgctcaatttcgcggcggtgttcaccacaccgtgcgtgttctacgtgcagaacaac
cagtgggcaatctcgatgccggtatccaggcagaccgccgcaccatctatcgcgcacaag
gcgattggctacgggatgccaggcatccgggtggacggcaacgacgtgctggcatgctat
gcggtgatggccgaagctgccgctcgggctcgggccggcgacggtccaacgctgatcgag
gcggtcacttaccgtcttggtccgcacaccaccgccgatgatccaacccggtaccgcagc
caggaggaggtggaccgctgggcgacgctggacccgattccgcgctatcgcacttactta
caagatcagggcctgtggtcgcaacgcctcgaggaacaggtgacggctcgggcaaaacac
gtgcggtccgagctacgcgacgcggtctttgatgcgcctgacttcgacgtcgatgaggtg
ttcaccacggtgtacgccgaaatcacacccgggttgcaggcgcagcgcgaacagctgcgt
gccgaactggcgcggactgactga
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