Mycobacterium canettii CIPT 140010059: MCAN_37251
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Entry
MCAN_37251 CDS
T01585
Symbol
gshA
Name
(GenBank) glutamate--cysteine ligase GSHA (gamma-glutamylcysteine synthetase) (gamma-ECS) (GCS) (gamma-glutamyl-L-cysteine synthetase)
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
mce
Mycobacterium canettii CIPT 140010059
Pathway
mce00270
Cysteine and methionine metabolism
mce00480
Glutathione metabolism
mce01100
Metabolic pathways
mce01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
mce00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
MCAN_37251 (gshA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
MCAN_37251 (gshA)
Enzymes [BR:
mce01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
MCAN_37251 (gshA)
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Gene cluster
GFIT
Motif
Pfam:
GCS2
Motif
Other DBs
NCBI-ProteinID:
CCC46056
UniProt:
A0AB72XQV4
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All DBs
Position
complement(4216407..4217705)
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AA seq
432 aa
AA seq
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MTLAAMTAAASQLDNAAPDDVEITDSSAAAEYIADGCLVDGPLGRVGLEMEAHCFDPADP
FRRPSWEEITEVLEWLSPLPGGSVVSVEPGGAVELSGPPADGVLAAIGAMTRDQAVLRSA
LANAGLGLVSLGADPLRSPVRVNPGARYRAMEQFFAASHSGVPGAAMMTSTAAIQVNLDA
GPQEGWAERVRLAHALGPTMIAIAANSPMLGGRFSGWQSTRQRVWGQMDSARCGPILGAS
GDHPGIDWAKYALKAPVMMVRSPDAQDTRAVTDYVPFTDWVDGRVLLDGRRATVADLVYH
LTTLFPPVRPRQWLEIRYLDSVPDEVWPAVVFTLVTLLDDPVAADLAVDAVEPVATAWDT
AARIGLADRRLYLAANRCLAIAARRVPTELIDAMQRLVDHVDRGVCPADDFSDRVIAGGI
ASAITGMMHGAS
NT seq
1299 nt
NT seq
+upstream
nt +downstream
nt
atgacgcttgccgccatgaccgccgcggcctcgcagctggataacgctgccccggacgac
gtcgagatcaccgattcgtcggccgccgcggaatacatcgcggacggctgcctcgtcgat
ggtccgttgggacgcgtcggtctggagatggaggcgcactgcttcgacccggccgatccg
tttcgccggcccagctgggaagagatcaccgaggttctcgaatggctcagtccgctgccg
ggcggcagcgtggtcagcgtggagcccggtggcgccgtcgaactgtccggaccgcccgcc
gacggcgtgctggcagccatcggtgccatgacgcgcgatcaggcggtgctacggtcggcg
cttgccaatgccgggctgggtttggtctccctgggtgcagacccgctgcggtcgccggtg
cgggtcaatccgggcgcacgctatcgggccatggagcagtttttcgccgccagccatagc
ggagtgccgggtgcggcgatgatgacctcgacagccgcgatccaggtcaatctggatgcc
ggaccgcaggaaggatgggctgagcgagtccgcctggcgcacgccttggggccgacgatg
atcgcgattgccgccaactccccgatgctgggcggccggttttccggctggcagtccacc
cggcagcgggtgtggggccagatggactccgcgcgctgcggccccattcttggtgccagt
ggcgaccaccccggcatcgactgggctaagtatgccttgaaggcgccggtgatgatggtg
cgaagcccggacgctcaagacacccgtgcggtgacggactacgtgcccttcaccgactgg
gttgacggtcgggtgctgctggacggtcgccgcgctaccgtcgccgacctggtttaccac
ctgacaacgttgttcccgccggtgcgtcctcggcaatggctggaaattcgctacctcgac
agcgtgcccgacgaggtgtggcccgcggtggtgttcaccttggtgacactgctcgacgac
ccggtggcggcagatttggcggtcgacgcggtcgaaccggtggccacggcctgggacacc
gcggcccggatcggcctggccgaccggcggctctacctggcagccaacagatgcctggcc
atcgccgcgcggcgggtaccgactgaactcatcgacgcgatgcagcggttggtggaccac
gtcgacaggggtgtttgcccggcagacgatttctccgaccgggtgatcgcgggcggcatc
gcgtcagccatcaccgggatgatgcacggggcgtcgtga
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