Mugil cephalus (flathead mullet): 125015488
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Entry
125015488 CDS
T08342
Symbol
lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
mcep
Mugil cephalus (flathead mullet)
Brite
KEGG Orthology (KO) [BR:
mcep00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mcep01001
]
125015488 (lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mcep04131
]
125015488 (lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mcep04147
]
125015488 (lrrk2)
Enzymes [BR:
mcep01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
125015488 (lrrk2)
Protein kinases [BR:
mcep01001
]
Serine/threonine kinases: TKL group
LRRK family
125015488 (lrrk2)
Membrane trafficking [BR:
mcep04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
125015488 (lrrk2)
Exosome [BR:
mcep04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
125015488 (lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_8
LRR_4
Roc
Ras
COR-A
COR-B
LRR_14
Beta-prop_RSE1_2nd
WDR55
Arf
Ank_2
Ank_3
AAA_22
Viral_helicase1
Beta-prop_EML_2
nSTAND3
TPR_IPO5
WD40_2
AAA_16
NACHT
Rad17
LRR_NXF1-5
Beta-prop_THOC3
ATP_bind_1
cobW
MobB
G-alpha
PduV-EutP
TniB
TrwB_AAD_bind
AAA_7
Septin
T2SSE
NB-ARC
Ank_4
ABC_tran
AAA_30
Gtr1_RagA
TsaE
UvrD-helicase
Motif
Other DBs
NCBI-GeneID:
125015488
NCBI-ProteinID:
XP_047453370
LinkDB
All DBs
Position
10:23302507..23335385
Genome browser
AA seq
2550 aa
AA seq
DB search
MVNKEELEERLRKLLVRLNTPQEDRRLDTLIQIIKDLLFLAHTDYAAELFEDKEVHVPLT
RVLSSYISSAGVQQVGWSLLCQLIEICPTTLDQLTRPLQSAPESEVLGLHQQILKVLSQY
STDCRVTMVGLRALALLLRSDTIPLLVLDEEEDVFGLVVQAMKTFPTSEEVQFQGCGALQ
LLLERVSDDHLVEFVENQDHVVVLAALRRFSDSPELLQRVLKVLLPLARPSSNLEVLMSG
GTRCYSMIIAAMDAFPEVEKLQETACCLFKMFTSGHNKSINESYYNILVLNGVQRVALRA
CQTFPDNALLQAAALSCLADLTATIVQNKAVAEQGLEDGEEEENRGKGEVEDMGLGWMKD
CCVALELHAAEPEVQEAASWAIHNLLLHGAGGTFTEEEQNERAPVHRQLMAAMLLHSSSP
SVFEAATSALGTLITNNSKMPSLLLSSGLHVNLVEMMKRHSTSVEVSISACRLLNLLFQG
RTASLDELNMAMSQILSNMKVHNFEPEVQLEALQASLVFLCPDRSLREHGVSVSDPDMAD
VSLKVLKTQCVVEGAHTLYLEVLNRFISSSAIQRCGLKVLCVLADCSGAVDLLCQQGAID
TVLHTLQMFPQEREIHYWGLTLLNYLVAKKKLSRMIVPVLASVVVASLIQYREDSEMLLK
CFHVALRMLDACSGAAAELHREDFDRQIFQHLRDETDQSFSPLRKSVCLALSKMWCNSDL
HYSMLEKACKEGDTTMAECLIELGADINRKTKTDSLIYQVCEGGGPLELVELLLSRGAHE
QHLRRALAVSVKKGDGPTVIQLLGRLGLDLNNSALCLGGFRLGRLEASWLSPLLADRGRA
QSLRFNNTKGMSLARYIQSLQRSKSVSCPSRTTADPCLTSGYISDESDDSSFSFVSTEDS
LFFNDDLESDGSDSLSGALSPKPLNNSTEELRGESFKRKQTRRRHASAENGQAESEHTEP
VPTSRRYGRKSSSQKVLGFGENSAALPKEKERIRLLDLSGNELDSLSCLMDHGLVQQQLG
QLLRLDLSHNILLEFPSVLCQCLKSLTRLDLQGNHLQSLPTELLSLPSLNMLNVSRNCVG
PVLTFDPAVTCPSLRQLNLSFNKITTFPHELCRATDHLEELFLEGNSVTELCTPLCLPEI
KLLDVSKNSVENISPDFLTGCPKLETFNASMNKICSLSHLPSKITTLKLANNSFTYIPEA
ILELPNLRSLDMKTNDIAILPAPGSWASSNIRELIFSQNCIKALDLSGPINKWARLEKLH
LSDNKLSEIPPQIGLLEGLTSLDVSRNTNVRSFPDEMGKLCRLWDLPLDGLQLQLDLKLI
GSKTKDIVRFLQQRLKKAVPYYRMKLIVVGNAGSGKTTLIQQLMKMKRSQMKQAAVGIDV
RDWPIRDPDKKKMVLNVWDFSGGEEFSGSHPHFLTSRALYLVVYNLSKGASEVDALKPWL
FNIKAVAPLSPVILVGTHKDVSEESQVQACLIKIKEELLNHQDFPAIRDYHMVSVCEDSD
ALSMLRKAIASEVTSFKIQGQRVIGQLVPDSYVELERRVLQERTRVPPEFPVLRHRELLQ
LIQDSQLQLEEAELPHAIHFLSEVGVLLHFDDPGLQLQELYFIDPQWLCNLLSQKLTWKS
FGLKGNPKGVLQRSAVEKFLFDTKCFPKSHLTQFLKLLEKFQIALPFSEDQLLVPSSLSK
YRPVIELPHCENSEVIVRLYEMPYFPMDYWSRQISRLLEVSSYLLCGREKVVRPNQIYWR
RGVYLHWSTEAYCLVEAASEEENPSSFVRITVPSSRKGQVLLGQVVDHIDSLLEEWFPGL
LNTDIHGSGESLLKKWALYSFEDGQEWSKILLEDLFACFDNDFLLVNPKDPRSTLPISQI
APDLVLTDQPASTILDSEELEVDMSKENRLGDGGFGTVYRGVYKNEEVAVKIFNKHASEL
YIYRLLRQELTVLGHLRHPSLVGLLAAGSAPQVLVMELALRGSLDSLFEHENSSLNQKLQ
HRIALQVADGLRYLHSTMIIYRDLKPHNVLLFNLKTDSEMIAKITDYGIAQYCCSMGVRS
SEGTPGFRAPEVARGNVTYNQQADVFSFGLLLYDLLTCGERISDGMKFPSEFDEIAVQGK
LPDPVEHYGCSPWPGFQALMKDCLRENPQDRPTSAQVFDRLNSGEMLCLMREIVVSRLFN
AECFTVSSGSKAGPSSDHRAWLGGGSSTEKLGSITEVDLDTNAVKTQEVDTSPVLCLVTV
QIPDEACDWLVAGTQSGSLVVISTRDTSTWHYLQAVTDSVTSLYFHAHPQPTHRKNYLLV
GTADGILSVYEDSVLKQGNGQPVKTLTVGNVNTPVMCLGQSVHSLDSKSVWAGCGSKILS
FTIDYSVCKTIDTRPNLIFPQQRSLGSEVCVSRLVVDKYVYLSKAGASTVEVWDKRSERM
VDSIDCAQIIRHESSSRGRQGSEAGLPTDASPHWVTVKALLVQSTATLWIGTRGGHLLLL
ELSKHQTLHVMNPRCDSIRCMASAFIQTLNWKNVVLVLGRRLSQDKNRDDKESVLMVWNS
MLPVEVKDLKKHCEKRERIAAKMREQLHHN
NT seq
7653 nt
NT seq
+upstream
nt +downstream
nt
atggttaacaaagaagagttggaggaaaggctgaggaaactcctggtgaggttgaatact
ccccaagaagacagacgactggatacgctgattcaaatcatcaaggatttgctcttcctg
gcgcacacggactatgcagcagaactgtttgaagacaaagaagtccacgtccccctcacg
cgggtgctgtcatcatacatcagcagcgcaggagttcagcaggtgggttggtcattgctg
tgtcagctgattgaaatatgccccactacactggaccagcttaccagacctttgcagtcg
gccccagagtcggaggttctgggattgcaccagcagatcctgaaggtgctgtctcagtac
agcacagactgtcgagtgaccatggttggactcagagccctggctctactgctcagatca
gacacgattcctctgctggtgctggatgaggaggaggatgtgtttggcctcgtggtgcag
gcgatgaagacgtttcccactagtgaagaggtgcagttccaaggatgtggagctctgcag
ctgctgctggagagagtaagtgacgaccacctggtggagtttgtggagaaccaggatcat
gttgtggttctggcggctctgcggaggttcagcgacagcccggagctgctccaaagggtg
ctgaaagtgctgctgcctctggctcgtcctagtagtaatttggaggtgctgatgtcagga
ggcactcggtgttacagcatgatcatcgccgccatggacgccttccccgaggtggagaag
ctgcaggagacggcctgctgccttttcaagatgtttacgtcagggcacaacaagagcata
aatgagagttactacaacatcctggtgctgaacggagtccagagggttgcactcagagcc
tgtcagaccttccctgacaatgccctgctgcaggctgctgctctctcctgcctggctgac
ctcactgccaccatcgtgcagaacaaggcggtggcggagcagggcctggaggacggggag
gaggaggagaaccggggtaagggggaggtggaggacatgggcctgggctggatgaaagac
tgctgcgtcgcactggagcttcacgctgctgagccagaagttcaggaagctgcaagctgg
gccattcacaacctgttattgcacggagccggtggaacatttacagaagaggagcagaat
gaaagagctcctgttcatagacagttaatggcagcgatgctgctccattcctcctctccc
agtgtgtttgaagctgctaccagtgccttgggcacactcattacaaacaacagtaaaatg
ccttctctgctgctgtccagtggcctccacgtcaatctggtggagatgatgaagagacat
tcaacctcagtagaagtttccatcagcgcctgcagactgttaaacctgctcttccaggga
aggacagccagtttggatgagttgaacatggccatgagtcagatcctcagcaacatgaag
gtccacaacttcgagccggaggttcagctggaggccctgcaggccagcttggtcttcctt
tgtccagacaggagtttaagggagcacggcgtctcagtctctgatcctgacatggccgac
gtgtctctgaaggtcctgaaaacccagtgtgtggtggaaggagctcacactctctacctg
gaggttctcaacaggttcatcagcagctctgccatacagaggtgtgggttgaaggtgctg
tgtgttctggccgactgctctggtgcagtggacctactctgccagcagggggcgatagac
acagtgctgcatacactacaaatgttcccacaggaacgagagatacactactggggcctg
accctgctcaactacctcgtagccaaaaagaagctgtcaagaatgattgtacctgttctg
gcctctgttgtggtggcctccctcatccagtacagagaagactcagagatgctgctgaag
tgtttccacgtggcgttgaggatgctggacgcctgttcgggagcagctgctgaactgcac
agggaagactttgacaggcagatcttccagcaccttagagacgagacggaccagagcttc
agcccactgcggaagtccgtgtgtctggctttgtccaaaatgtggtgcaactctgaccta
cactacagcatgctggaaaaggcctgcaaggagggagacacgaccatggccgagtgtctc
atcgagctgggtgctgacatcaacaggaagacaaagactgattctctcatttaccaggtg
tgtgaagggggtggaccactagaactggtggagcttctactcagccgaggtgcccacgag
cagcatctccgccgagctctggcagtgagcgtgaagaagggagacgggcccacagtcatc
cagctgttgggccgtctgggactggacctcaacaacagcgccctctgcctgggcggcttc
aggctgggccgcctggaggcctcctggctgagccccctgctggctgatagaggcagagct
cagagtctacgttttaacaatactaaaggtatgagcttagccaggtacatccagtctctc
cagaggtccaagagtgtgagctgtccttccaggacaacagccgacccgtgtctgacatcc
ggctacatttccgacgagagtgatgactccagtttcagcttcgtctccacggaagacagc
ttgttttttaatgacgacttggaaagtgatggaagtgattcactgtccggtgctctgtct
cctaagccacttaacaattcaacagaggagctgaggggggaatccttcaaaaggaagcaa
acgcgtcgtagacatgccagcgcagagaatggtcaagctgagagtgaacacactgagcct
gtacctacgtctagaagatatggaaggaaaagctcgagtcaaaaagtgctgggatttggt
gagaactctgctgccctgcccaaagagaaggagaggatccgcctgctggacttgtcaggg
aacgagttggactctctgtcctgtctaatggaccacggtttagtccagcagcagctgggg
cagctcctccgcctggacctgagccacaacattctgctggagtttccctctgtcctgtgc
cagtgtttgaagagcctgactcgactggacctgcaggggaaccacctccagtctctgccc
acggagctgctgtctctgccgtcactgaacatgctgaacgtctcccggaactgtgtcgga
cccgtgctgacctttgaccccgctgtgacctgcccgtcactgaggcagctcaacctttca
ttcaacaaaatcaccacgttccctcatgagctgtgccgcgccaccgatcacctggaggag
cttttcttggaaggtaacagtgtaactgagctgtgcactccgctgtgtctaccggagatc
aagctgctcgatgtgagcaagaacagcgtggagaatatttctccagacttcctgactggc
tgccccaaactagaaacatttaatgcctccatgaacaaaatctgttccctgtcacatctt
ccatccaaaattacgacactgaaactagccaacaacagctttacgtacatccctgaggct
atacttgagctcccaaacttgcggtcactggacatgaaaaccaacgatattgccatccta
cccgctccggggtcctgggcgtccagcaacattagagaactcatctttagtcagaactgt
atcaaagctctggatctgagcggaccaatcaacaaatgggccagactggagaaactccac
ctgagtgacaacaagctctctgagatccctccacagattgggctgttggaaggtctcacc
tccctagatgtgagtcgtaacactaacgtgcggtcgttcccagatgagatgggaaaactg
tgcagactctgggacctgccgcttgatggccttcagctgcagctggacctcaaactcatt
ggcagcaagaccaaagacattgttaggttcttgcagcagcgtctgaagaaggcggtgccg
tactaccgcatgaagctgattgtggtggggaatgctggcagtgggaagacgaccctgata
cagcagctgatgaagatgaagcgctcccagatgaagcaggctgcggttggcatcgacgtc
cgagactggcccatcagggatccggacaagaagaaaatggtgctgaatgtttgggacttt
tcagggggagaggagttcagcggctctcaccctcacttcctgacgtccagagctctctac
ctggttgtgtacaacctcagcaaaggagccagtgaggtggatgccctcaaaccctggctc
ttcaacatcaaagcggtagctcctctttccccggtcattctggtgggaacccacaaagat
gtaagcgaggagtcacaggtgcaggcctgcctgatcaaaatcaaagaggagcttctgaac
catcaggacttccctgccatcagggactatcacatggtctccgtgtgcgaggactcggat
gccttgtccatgctccgcaaggccatcgcgagcgaggtcaccagctttaagatccagggc
caacgtgtgataggtcagctggttccagacagttatgtggagctggagcgccgggttctc
caggagaggaccagggttccaccagagttccccgttctcaggcaccgtgagctgctgcag
cttatccaggacagtcagctgcagctggaggaagcagagctgccccacgcgatccacttc
ctcagtgaagttggggttttattgcactttgatgatcctggacttcagcttcaagagctc
tattttatcgacccacagtggctgtgcaacctcctctcccagaaactgacttggaagagc
tttggcttgaagggcaatcctaaaggagttctgcagcgctccgctgtggaaaagtttctg
tttgataccaaatgttttccaaagagccacctgacgcagttcctcaaactgctggagaag
tttcagatcgctcttcccttcagcgaggaccagctgcttgtacccagcagtttgtccaaa
tacagaccagtaatagagctgcctcactgtgagaactcagaggtgattgtgcgcctttat
gagatgccctacttccccatggactactggtctcggcagatcagccgactactggaggtc
tcctcctacctgctttgtggaagagaaaaagtggttcgacccaaccagatctactggagg
aggggagtttacctgcactggtccactgaagcgtactgtctggtggaggctgcctcagag
gaggaaaatccctccagctttgtcaggatcactgtcccctcttcccgtaaaggccaagtg
ttactgggtcaagtggtggatcacatcgactccctgctggaggaatggtttcctggcctg
ctcaatactgacatccatggcagtggagaatctctgctaaagaagtgggcgctgtacagc
ttcgaggacgggcaggaatggagcaagatcctgctggaagacctattcgcttgttttgac
aacgattttctgctggtgaacccaaaggatccacgctccacacttcccatctctcagatt
gccccagacttggtactgactgaccagcctgcaagtacaatcctggacagtgaagagctg
gaggtagatatgtctaaagagaaccgtctcggggacggtggctttgggactgtttaccga
ggtgtctataaaaatgaagaagtagcagtgaagatattcaacaagcatgcgtctgagctt
tacatctacagactcctcagacaggaattgaccgttttgggtcatctccgtcaccccagc
ctcgtcggcctcctggcagccggctcagctcctcaggtcctggtgatggagctggctctg
cgaggctctctcgattccctttttgagcatgagaacagtagcctcaaccaaaagttgcag
cacaggattgccctgcaggtggcagatggactcaggtaccttcactccaccatgatcatc
taccgggatctgaagccccacaacgtcctcctgttcaacctgaagaccgactctgagatg
atcgctaaaatcactgactatggcatcgctcagtactgctgcagcatgggagtgaggagc
tcagaggggacaccaggcttccgagcaccagaggttgcccgaggtaatgtgacttacaac
cagcaggctgatgtgttctcatttggcctgctcctctatgacctcctgacctgtggcgag
cgcatttctgatggcatgaagttccccagtgagtttgatgaaatcgcagtgcaggggaaa
ctgccagatccggtggaacactacggttgttcaccgtggccaggttttcaggccctgatg
aaggactgtctgagggaaaacccacaggaccgacccacttctgctcaggtgttcgatcgg
ctgaattcaggtgaaatgctgtgtctaatgcgggaaatcgtagtttctcggctgttcaac
gccgagtgcttcacagtgagctcaggcagcaaagctgggccctcgtcagaccacagggcc
tggcttggtgggggcagcagcaccgagaagctgggttccatcacagaagtggacctggac
accaacgctgtcaaaacacaggaggtcgacaccagtcctgtcctgtgccttgtgacggtc
caaatcccagacgaggcctgtgactggcttgtagcgggcacccagtctggctccctggtg
gtcatcagcacgcgggacacatccacctggcactacctgcaggctgtcaccgattctgtc
acctcactgtacttccatgcgcacccccaaccaacacacagaaagaattatttgctggtt
ggaacagcagatggaattctcagtgtttacgaggactctgtgctcaagcaggggaacggg
cagccagttaaaactctaaccgtgggtaacgtcaacactcccgtcatgtgtctggggcag
tcggtgcattcgctggacagcaaatctgtgtgggctggctgcgggtccaagatcctctcc
ttcaccatcgactacagcgtctgcaagaccatcgacacaaggccaaacctcatcttcccg
cagcagcggtcactgggcagtgaggtgtgcgtgtctcgtttggttgtggataaatacgtg
tacctgagcaaagccggggcatccactgtcgaggtttgggacaagaggagtgagaggatg
gtggactccatcgactgtgctcagattattaggcatgaatcgtccagcagaggcaggcag
ggcagtgaagccgggctgcccaccgatgcgtctccccactgggtcacggtgaaggccctg
ctggtgcagagcactgcaactctctggatcggcactagggggggccacctgctgctgctg
gagctctccaaacaccagaccctgcacgtcatgaacccccgctgtgactccatccgctgc
atggcctccgcattcatacaaactcttaactggaagaacgtggtgctggttttgggccga
agactctcacaagacaaaaacagagatgacaaggagtccgtgctgatggtgtggaacagc
atgctgcccgtggaggtcaaggacctgaagaagcactgcgagaagagggagcggatcgcg
gccaaaatgagagagcagctccatcacaactga
DBGET
integrated database retrieval system
