Mugil cephalus (flathead mullet): 125019173
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Entry
125019173 CDS
T08342
Symbol
gclC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
mcep
Mugil cephalus (flathead mullet)
Pathway
mcep00270
Cysteine and methionine metabolism
mcep00480
Glutathione metabolism
mcep01100
Metabolic pathways
mcep01240
Biosynthesis of cofactors
mcep04216
Ferroptosis
Module
mcep_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
mcep00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
125019173 (gclC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
125019173 (gclC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
125019173 (gclC)
Enzymes [BR:
mcep01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
125019173 (gclC)
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
125019173
NCBI-ProteinID:
XP_047459676
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Position
13:12291067..12301308
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AA seq
630 aa
AA seq
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MGLLSQGSPLNWEETRKYADHIRKHGIIQFLNIYNKVKERQKDVLKWGDEVEYMLLELDD
KDEKVRIVLSGGDVLETLQDQGEKVNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EGNMRKRRREASSVLNQNETLCSITAFPRLGCPGFTKPECRPTPVEKGVSKSLFFPDEAI
NRHPRFSTLTRNIRHRRGEKVAINVPIFKDKCTPSPFVEEFPEDDGEAARAALPDHIYMD
AMGFGMGNCCLQVTFQACSIDEARYLYDQLATFCPIVMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTQEERGLKPLKNNKYRIFKSRYDSIDSYLSSCGEKYNDIDLTIDEEINKQLL
AAGIDKLLAQHIAHLFIRDPLSVFEEKIHLDDENESDHFENLQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENAAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRNAV
HEGMFYFRKDIFKGCSSVPDGAASAQNGLDADGANEEYMLMSIDTIINGKEGVFQGLIPI
LNCYLENMEVDVDTRCTILNYLKLIKKRASGELMTMAKWMREFVAKHPQYKQDSVITDKI
NYDLIKKCDRIAKGEEQCPELFGNPVNKFK
NT seq
1893 nt
NT seq
+upstream
nt +downstream
nt
atgggtctgctgtcacagggatcaccactgaactgggaagaaaccaggaagtatgccgac
cacatcagaaagcacggtatcatccagtttctgaacatctacaacaaggtgaaggagcgt
cagaaagatgtgctgaaatggggcgacgaggttgagtatatgctattggaattggatgac
aaggatgagaaggtccgaattgtcctgagcggcggggacgtcctggagaccctccaagac
cagggtgaaaaggtcaatcccaatcaccctacactctggagaccagagtatggcagctac
atgatcgaggggactccggggcagccgtacggcggcaccatgtccgagttcaacaccgtg
gagggcaacatgaggaagaggcgacgagaggcgtcatctgtcctgaaccagaatgaaacc
ctgtgctccattaccgcctttccaaggttaggttgcccaggtttcaccaaaccagagtgc
cggccgactcccgttgagaagggagtgtcgaagtcgctgtttttcccagatgaagccatc
aacaggcacccaagattcagcaccctgaccagaaacatacgtcacagaagaggagagaaa
gtcgcaataaatgtgccaatctttaaagacaagtgcactccatctccatttgtggaggag
tttcctgaggacgatggcgaagcagcgcgggcggctctgcccgaccacatctacatggac
gccatgggctttggcatggggaactgctgcctgcaggtgacattccaggcttgtagcatt
gatgaggcgaggtatctatacgaccaactagcgacgttctgccccattgtgatggctctg
agtgcagcctcacccttctacagaggctacgtgtcggatatcgattgtcgctggggggtt
atttctgcctcggtggatgacaggacacaggaggagcgcgggctgaagcccctgaaaaac
aacaaatacaggatcttcaagtcgagatacgactcgattgacagctacctgtccagctgt
ggtgagaagtacaacgacattgatttgacgatagacgaggagatcaacaagcagctgctc
gcagccggaattgacaagctgctggctcaacacatagcacacctcttcatccgggatcct
ctctctgtgtttgaggagaaaatacacttggatgatgaaaacgagtcggatcactttgag
aacctccagtcgaccaactggcagacgatgaggtttaaacctccacctccgaactctgat
atcggctggagagtggagttccgccccatggaggtgcagctaactgactttgaaaacgct
gcatacgtggtcttcgtcgtcctgctcacccgagtgatcttgtcctacaagctggacttc
ctgatccccttgtcaaaggttgatgagaacatgaaggtggcgcagaagaggaacgctgtc
cacgagggcatgttttacttccgaaaggacatctttaaaggctgcagctcggtccccgat
ggcgccgcctctgctcagaacggcttggacgctgacggtgctaacgaggagtacatgctg
atgagcattgacaccatcatcaacggaaaggagggagtatttcaagggctgatcccaatc
ctcaactgctacctggaaaacatggaggttgatgtggacaccaggtgcaccattttaaat
tatctgaagctcatcaagaagcgcgcctcaggggaactgatgaccatggccaagtggatg
agggagtttgtggccaagcacccgcagtacaagcaggacagcgtcataactgacaagatc
aactacgacctgatcaaaaagtgcgacagaatcgccaagggcgaagagcagtgccccgag
ctctttggaaacccagttaacaagttcaaatga
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