Macaca fascicularis (crab-eating macaque): 101865903
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Entry
101865903 CDS
T02918
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
mcf
Macaca fascicularis (crab-eating macaque)
Pathway
mcf00260
Glycine, serine and threonine metabolism
mcf00630
Glyoxylate and dicarboxylate metabolism
mcf00670
One carbon pool by folate
mcf01100
Metabolic pathways
mcf01200
Carbon metabolism
mcf01230
Biosynthesis of amino acids
mcf01240
Biosynthesis of cofactors
mcf01523
Antifolate resistance
Module
mcf_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
mcf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
101865903 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
101865903 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
101865903 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101865903 (SHMT2)
Enzymes [BR:
mcf01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
101865903 (SHMT2)
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Gene cluster
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Motif
Pfam:
SHMT
Motif
Other DBs
NCBI-GeneID:
101865903
NCBI-ProteinID:
XP_005571353
Ensembl:
ENSMFAG00000002112
UniProt:
G7PIU7
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Position
11:54032099..54037157
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AA seq
513 aa
AA seq
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MSGVLGLASQAEPFRPALSPADDATEPHCLHQTGVPAAVRAGRRWNGLCRDGGSWSGWPF
GLSTARQPRLRLGKQTGAGQARRACRTVILRCGSCCRGRRTGSVVAWSSLPQRYYGGAEV
VDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGH
LTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYDQLALTARLFRPRLIIAGTSAYARL
IDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIF
YRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYS
LQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNT
CPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKTKTAKLQDFKSF
LLKDSETSQRLADLRQRVEQFARGFPMPGFDEH
NT seq
1542 nt
NT seq
+upstream
nt +downstream
nt
atgagtggagttctcggcctggcctcacaagctgagccttttcggccagctctgagccct
gcagatgatgcaaccgagcctcactgcttgcatcagacaggggtcccggcggcagtgagg
gctggaaggaggtggaacggcctctgcagagatgggggcagctggtcaggatggccattc
gggctcagcacagcaaggcagcccagactcagactggggaagcaaacaggggctggacag
gccaggagagcctgtcggacagtgatcctgagatgtgggagttgctgcagagggagaagg
acaggcagtgtcgtggcctggagctcattgcctcagagatattatgggggagcagaggtg
gtggatgaaattgagctgctgtgccagcgccgggccttggaagcctttgacctggatcct
gcacagtggggagtcaatgtccagccctactctgggtccccagccaacctggctgtctat
acagcccttctgcaacctcatgaccggatcatggggctggacctgcccgatgggggccat
ctcacccacggctacatgtctgacgtcaagcggatatcagccacgtccatcttcttcgag
tctatgccctataagctcaatcccaaaactggcctcattgactatgaccagctggcactg
actgctcgacttttccgaccgcggctcatcatagctggcaccagtgcctatgctcgcctc
attgactatgcccgcatgagagaggtgtgtgatgaagtcaaagcacacctgctggcagac
atggctcacatcagtggcctggtggctgccaaggtgattccctcgcctttcaagcacgcg
gacatcgtcaccaccactactcacaagactcttcgaggggccaggtcagggctcatcttt
taccggaaaggggtgaaggctgtggaccccaagactggccgggagatcccttacacattt
gaggaccgaatcaactttgctgtgttcccatccctgcaggggggcccccacaatcatgcc
attgctgcagtagctgtggccctaaagcaggcttgcacccccatgttccgggagtactcc
ctgcaggttctgaagaatgctcgggccatggcggatgccctgctagagcgaggctactca
ctagtatcgggtggtactgacaatcacctggtgctggtggacctgcggcccaagggcctg
gatggagctcgggctgagcgggtgctggagcttgtatccatcactgccaacaagaacacc
tgtcctggagaccgaagtgccatcacaccggggggcctgcggcttggggccccggccttg
acttctcgacagttccgtgaggatgacttccggagagttgtggactttatagatgaaggg
gtcaacattggcttagaggtgaagactaagactgccaagctccaggatttcaaatccttc
ctgctcaaggactcagaaacaagtcagcgtctggccgacctcaggcaacgggtggagcag
tttgccaggggcttccccatgcctggttttgatgagcattga
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