KEGG T02918: 101865903

Macaca fascicularis (crab-eating macaque): 101865903

Entry

101865903         CDS       T02918

Symbol

SHMT2

Name

(RefSeq) serine hydroxymethyltransferase, mitochondrial isoform X1

K00600

glycine hydroxymethyltransferase [EC:2.1.2.1]

Organism

mcf Macaca fascicularis (crab-eating macaque)

Pathway

mcf00260

Glycine, serine and threonine metabolism

mcf00630

Glyoxylate and dicarboxylate metabolism

mcf00670

One carbon pool by folate

mcf01100

Metabolic pathways

mcf01200

Carbon metabolism

mcf01230

Biosynthesis of amino acids

mcf01240

Biosynthesis of cofactors

mcf01523

Antifolate resistance

mcf04981

Folate transport and metabolism

Module

mcf_M00141

C1-unit interconversion, eukaryotes

Brite

KEGG Orthology (KO) [BR:mcf00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    101865903 (SHMT2)
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    101865903 (SHMT2)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    101865903 (SHMT2)
09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    101865903 (SHMT2)
09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    101865903 (SHMT2)
Enzymes [BR:mcf01000]
2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.1  glycine hydroxymethyltransferase
     101865903 (SHMT2)

SSDB

Motif

Pfam:

SHMT

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

Ensembl:

UniProt:

LinkDB

Position

11:join(64031948..64032087,64032646..64032843,64033555..64033755,64034054..64034135,64034296..64034418,64034545..64034684,64035021..64035186,64035404..64035503,64035592..64035747,64035846..64035953,64036077..64036204)

AA seq 513 aa
MSGVLGLASQAEPFRPALSPADDATEPHCLHQTGVPAAVRAGRRWNGLCRDGGSWSGWPF
GLSTARQPRLRLGKQTGAGQARRACRTVILRCGSCCRGRRTGSVVAWSSLPQRYYGGAEV
VDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGH
LTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYDQLALTARLFRPRLIIAGTSAYARL
IDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIF
YRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYS
LQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNT
CPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKTKTAKLQDFKSF
LLKDSETSQRLADLRQRVEQFARGFPMPGFDEH

NT seq 1542 nt +upstreamnt +downstreamnt
atgagtggagttctaggcctggcctcacaagctgagccttttcggccagctctgagccct
gcagatgatgcaaccgagcctcactgcttgcatcagacaggggtcccggcggcagtgagg
gctggaaggaggtggaacggcctctgcagagatgggggcagctggtcaggatggccattc
gggctcagcacagcaaggcagcccagactcagactggggaagcaaacaggggctggacag
gccaggagagcctgtcggacagtgatcctgagatgtgggagttgctgcagagggagaagg
acaggcagtgtcgtggcctggagctcattgcctcagagatattatgggggagcagaggtg
gtggatgaaattgagctgctgtgccagcgccgggccttggaagcctttgacctggatcct
gcacagtggggagtcaatgtccagccctactctgggtccccagccaacctggctgtctat
acagcccttctgcaacctcatgaccggatcatggggctggacctgcccgatgggggccat
ctcacccacggctacatgtctgacgtcaagcggatatcagccacgtccatcttcttcgag
tctatgccctataagctcaatcccaaaactggcctcattgactatgaccagctggcactg
actgctcgacttttccgaccgcggctcatcatagctggcaccagtgcctatgctcgcctc
attgactatgcccgcatgagagaggtgtgtgatgaagtcaaagcacacctgctggcagac
atggctcacatcagtggcctggtggctgccaaggtgattccctcgcctttcaagcacgcg
gacatcgtcaccaccactactcacaagactcttcgaggggccaggtcagggctcatcttt
taccggaaaggggtgaaggctgtggaccccaagactggccgggagatcccttacacattt
gaggaccgaatcaactttgctgtgttcccatccctgcaggggggcccccacaatcatgcc
attgctgcagtagctgtggccctaaagcaggcttgcacccccatgttccgggagtactcc
ctgcaggttctgaagaatgctcgggccatggcggatgccctgctagagcgaggctactca
ctagtatcgggtggtactgacaatcacctggtgctggtggacctgcggcccaagggcctg
gatggagctcgggctgagcgggtgctggagcttgtatccatcactgccaacaagaacacc
tgtcctggagaccgaagtgccatcacaccggggggcctgcggcttggggccccggccttg
acttctcgacagttccgtgaggatgacttccggagagttgtggactttatagatgaaggg
gtcaacattggcttagaggtgaagactaagactgccaagctccaggatttcaaatccttc
ctgctcaaggactcagaaacaagtcagcgtctggccgacctcaggcaacgggtggagcag
tttgccaggggcttccccatgcctggttttgatgagcattga

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