KEGG   Macaca fascicularis (crab-eating macaque): 101867234
Entry
101867234         CDS       T02918                                 
Symbol
VAV1
Name
(RefSeq) proto-oncogene vav isoform X1
  KO
K05730  guanine nucleotide exchange factor VAV
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
mcf04015  Rap1 signaling pathway
mcf04024  cAMP signaling pathway
mcf04062  Chemokine signaling pathway
mcf04510  Focal adhesion
mcf04517  IgSF CAM signaling
mcf04519  Cadherin signaling
mcf04650  Natural killer cell mediated cytotoxicity
mcf04660  T cell receptor signaling pathway
mcf04662  B cell receptor signaling pathway
mcf04664  Fc epsilon RI signaling pathway
mcf04666  Fc gamma R-mediated phagocytosis
mcf04670  Leukocyte transendothelial migration
mcf04810  Regulation of actin cytoskeleton
mcf05135  Yersinia infection
mcf05205  Proteoglycans in cancer
mcf05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mcf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    101867234 (VAV1)
   04024 cAMP signaling pathway
    101867234 (VAV1)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    101867234 (VAV1)
   04519 Cadherin signaling
    101867234 (VAV1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101867234 (VAV1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101867234 (VAV1)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    101867234 (VAV1)
   04660 T cell receptor signaling pathway
    101867234 (VAV1)
   04662 B cell receptor signaling pathway
    101867234 (VAV1)
   04664 Fc epsilon RI signaling pathway
    101867234 (VAV1)
   04666 Fc gamma R-mediated phagocytosis
    101867234 (VAV1)
   04670 Leukocyte transendothelial migration
    101867234 (VAV1)
   04062 Chemokine signaling pathway
    101867234 (VAV1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    101867234 (VAV1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    101867234 (VAV1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101867234 (VAV1)
SSDB
Motif
Pfam: RhoGEF SH3_1 SH3_2 CAMSAP_CH CH SH2 SH3_9 C1_1 PH SOS1_NGEF_PH CDC24 RHG20_PH C1_2 LZ3wCH
Other DBs
NCBI-GeneID: 101867234
NCBI-ProteinID: XP_005587784
Ensembl: ENSMFAG00000039752
UniProt: A0A2K5WYC0
LinkDB
Position
19:join(7537958..7538161,7584414..7584530,7585323..7585381,7585494..7585562,7585896..7586004,7586096..7586191,7589405..7589473,7589645..7589748,7590952..7591051,7592375..7592470,7592718..7592786,7592921..7593007,7593111..7593196,7593945..7594077,7596397..7596506,7597363..7597464,7597707..7597804,7597890..7597912,7598088..7598133,7600809..7600945,7601352..7601417,7606181..7606212,7611450..7611566,7613700..7613787,7615657..7615771,7616672..7616823,7620458..7620511)
AA seq 845 aa
MELWRQCTHWLIQCRVLPPSHRVTWDGAQVCELAQALRDGVLLCQLLNNLLPHAINLREV
NLRPQMSQFLCLKNIRTFLSTCCEKFGLKRSELFEAFDLFDVQDFGKVIYTLSALSWTPI
AQNRGIMPFPTEEESVGDEDIYSGLSDQIDDTVEEDEDLYDCVENEEAEGDEIYEDLMRS
EPVSMPPKMTEYDKRCCCLREIQQTEEKYTDTLGSIQQHFMKPLQRFLKPQDIEIIFINI
EDLLRVHTHFLKEMKEALGTPGAANLYQVFIKYKERFLVYGRYCSQVESASKHLDRVAAA
REDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQEAIEKENLRLAL
DAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLAHYGRPKIDGELKITSVERRSKM
DRYAFLLDKALLICKRRGDSYDLKDFVNLHSFQIRDDSSGDRDNKKWSHMFLLIEDQGAQ
GYELFFKTRELKKKWMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTF
YQGYRCHRCRAPAHKECLGRVPPCGRHGQDFPGTMRKDKLHRRAQDKKRNELGLPKMEVF
QEYYGLPPPPGAIGPFLRLNPGDIVELTKAEAEQNWWEGRNTSTNEIGWFPCNRVKPYIR
GPPQDLSVHLWYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKI
MTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFPFKEPEKRTISKPAVGS
TKYFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRVGWFPANYVEED
YSEYC
NT seq 2538 nt   +upstreamnt  +downstreamnt
atggagctgtggcgccagtgcacccactggctcatccagtgccgagtgctgccgcccagc
caccgcgtgacctgggatggggctcaggtgtgtgaactggcccaggccctccgggatggt
gtccttctatgtcagctgcttaacaacctgctaccccatgccatcaacctgcgtgaggtc
aacctgcgcccccagatgtcccagttcctgtgccttaagaacattagaaccttcctgtcc
acctgctgtgagaagtttggcctcaagcggagtgagctcttcgaagcctttgacctcttc
gacgtgcaggattttggcaaggtcatctacaccctgtctgctctgtcctggaccccgatc
gcccagaacagggggatcatgcccttccccaccgaggaggagagtgtaggtgatgaagat
atctacagtggcctgtccgaccagatcgacgacacggtggaagaggatgaggacctgtat
gactgcgtggagaatgaggaggcggaaggcgacgagatctatgaggacctcatgcgctcg
gagcccgtgtccatgccgcccaagatgacagagtatgacaagcgctgctgctgcctgcgg
gagattcagcagacggaggagaagtacacggacacactgggctccatccagcagcatttc
atgaagcccctgcaacggttcctgaaacctcaagacattgagatcatctttatcaacatt
gaggacctgcttcgtgttcatactcacttcctaaaggagatgaaggaagccctgggcacc
cctggcgcagccaatctctaccaggtcttcatcaaatacaaggagaggttcctcgtctac
ggccgctactgcagccaggtggagtcagccagcaaacacctggatcgtgtggccgcagcc
cgggaggacgtgcagatgaagctggaggaatgttctcagcgagccaacaacgggaggttc
accttgcgggacctactgatggtgcctatgcagcgagttctcaaatatcaccttcttctc
caggagctggtgaaacacacgcaggaggctatagagaaggagaacctgcggctggccctg
gatgccatgagggacctggctcagtgcgtgaacgaggtcaagcgagacaacgagacactg
cggcagatcaccaatttccagctctccattgagaacctggaccagtctctggctcactat
ggccggcccaagatcgacggggagctcaagatcacctcggtggaacggcgctccaagatg
gacaggtatgccttcctgctcgacaaagctctgctcatctgtaaacgccggggagactcc
tatgacctcaaggactttgtgaacctgcacagcttccagattcgggatgactcttcagga
gaccgtgacaacaagaagtggagccacatgttcctgctgattgaggaccaaggtgcccag
ggctatgaactgttcttcaagacaagagaattgaagaagaagtggatggagcagtttgag
atggccatctccaacatttacccggagaatgccaccgccaacgggcatgacttccagatg
ttctcctttgaggagaccacgtcctgcaaggcttgtcagatgctgcttagaggcaccttc
tatcagggctatcgctgccatcggtgccgggcacctgcacacaaggagtgtctggggagg
gtccctccgtgtggccgacatgggcaagatttcccgggaactatgaggaaggacaaactg
catcgcagggctcaggacaaaaagaggaatgagctgggtctgcccaagatggaggtgttc
caggaatactatgggcttcctccaccccctggagccattggaccctttctacgactcaac
cctggagacattgtggagctcacaaaggctgaggctgaacagaactggtgggagggcagg
aatacatctactaatgaaattggctggtttccttgtaacagggtgaagccctacatccgt
ggccctcctcaggacctgtctgttcatctctggtacgcaggccccatggaacgggcaggg
gcagaaagcatccttgccaaccgctcggacgggactttcttggtgcggcagagggtgaag
gatgcagcagaatttgccatcagcattaaatataacgtcgaggtcaagcacattaaaatc
atgacagcagagggactgtaccggatcacagagaagaaggctttccgggggcttacggag
ctggtggagttttaccagcagaactccctaaaggattgcttcaagtctctggacaccacc
ttgcagttccccttcaaggagcctgagaagaggaccatcagcaagccagcagtgggaagc
acaaagtattttggcacagccaaagcccgctatgacttctgtgcccgggaccgatcagag
ctgtcgctcaaggagggtgacatcatcaagatccttaacaagaagggacagcaaggctgg
tggcgaggggagatctatggccgggttggctggttccctgccaactacgtggaggaagat
tattctgaatactgctga

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