KEGG   Macaca fascicularis (crab-eating macaque): 101925060
Entry
101925060         CDS       T02918                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X4
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
mcf04010  MAPK signaling pathway
mcf04015  Rap1 signaling pathway
mcf04218  Cellular senescence
mcf04380  Osteoclast differentiation
mcf04620  Toll-like receptor signaling pathway
mcf04664  Fc epsilon RI signaling pathway
mcf04668  TNF signaling pathway
mcf04750  Inflammatory mediator regulation of TRP channels
mcf04912  GnRH signaling pathway
mcf04935  Growth hormone synthesis, secretion and action
mcf04936  Alcoholic liver disease
mcf05014  Amyotrophic lateral sclerosis
mcf05022  Pathways of neurodegeneration - multiple diseases
mcf05132  Salmonella infection
mcf05135  Yersinia infection
mcf05145  Toxoplasmosis
mcf05161  Hepatitis B
mcf05163  Human cytomegalovirus infection
mcf05167  Kaposi sarcoma-associated herpesvirus infection
mcf05169  Epstein-Barr virus infection
mcf05170  Human immunodeficiency virus 1 infection
mcf05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mcf05417  Lipid and atherosclerosis
mcf05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mcf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101925060 (MAP2K6)
   04015 Rap1 signaling pathway
    101925060 (MAP2K6)
   04668 TNF signaling pathway
    101925060 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    101925060 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    101925060 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    101925060 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    101925060 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    101925060 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101925060 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101925060 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101925060 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101925060 (MAP2K6)
   05161 Hepatitis B
    101925060 (MAP2K6)
   05163 Human cytomegalovirus infection
    101925060 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101925060 (MAP2K6)
   05169 Epstein-Barr virus infection
    101925060 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101925060 (MAP2K6)
   05135 Yersinia infection
    101925060 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101925060 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    101925060 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    101925060 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101925060 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    101925060 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101925060 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mcf01001]
    101925060 (MAP2K6)
Enzymes [BR:mcf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     101925060 (MAP2K6)
Protein kinases [BR:mcf01001]
 Serine/threonine kinases: STE group
  STE7 family
   101925060 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Haspin_kinase Choline_kinase DUF4344 APH
Other DBs
NCBI-GeneID: 101925060
NCBI-ProteinID: XP_045230435
Ensembl: ENSMFAG00000040095
UniProt: A0A2K5WZY2
LinkDB
Position
16:join(75738360..75738375,75832647..75832713,75844005..75844053,75844637..75844750,75846484..75846603,75847440..75847556,75848220..75848271,75850870..75850997,75852258..75852335,75853910..75854049,75863436..75863481,75869071..75869148)
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKGTDVASFVKLILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagcgaaaccctggccttaaaattccaaaagaagcattt
gagcaacctcagaccagttccacaccacctcgagatttagactccaaggcttgcatttct
attggaaatcagaactttgaggtgaaggcagatgacctagagcctataatggaactggga
cgaggtgcgtacggggtggtggagaagatgcggcacgtgcccagcgggcagatcatggca
gtgaagcggattcgagccacagtaaatagccaggaacagaaaaggctactgatggatttg
gatatttccatgaggacggtggactgtccattcaccgtcaccttttatggcgcactgttt
cgggagggtgatgtgtggatctgcatggagctcatggacacatcactagataaattctac
aaacaagttattgataaaggccagacaattccagaggacatcttagggaaaatagcagtt
tctattgtaaaagcattagaacatttacacagtaagctgtctgtcattcacagagacgtc
aagccttctaatgtactcattaatgctctcggtcaagtgaagatgtgcgattttggaatc
agtggctacttggtggactctgttgctaaaacaattgatgcgggttgcaaaccatacatg
gcccctgaaagaataaacccagagctcaaccagaagggatacagtgtgaagtctgacatt
tggagtctgggcatcacgatgattgagttggccatccttcgatttccctatgattcctgg
ggaactccatttcagcagctcaaacaggtggtagaggagccatctccacaactcccagca
gacaagttctctgcagagttcgttgactttacctcacagtgcttaaagaagaattccaaa
gaacggcctacatacccagagctaatgcaacatccatttttcaccctacatgaatccaaa
ggaacagatgtggcatcttttgtaaaactgattcttggagattaa

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