Macaca fascicularis (crab-eating macaque): 102115639
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Entry
102115639 CDS
T02918
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2 isoform X1
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
mcf
Macaca fascicularis (crab-eating macaque)
Pathway
mcf00140
Steroid hormone biosynthesis
mcf01100
Metabolic pathways
mcf05215
Prostate cancer
Module
mcf_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
mcf00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
102115639 (SRD5A2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
102115639 (SRD5A2)
Enzymes [BR:
mcf01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
102115639 (SRD5A2)
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Gene cluster
GFIT
Motif
Pfam:
Steroid_dh
DUF1295
DUF6832
PEMT
Motif
Other DBs
NCBI-GeneID:
102115639
NCBI-ProteinID:
XP_045225483
Ensembl:
ENSMFAG00000000955
LinkDB
All DBs
Position
13:join(90591470..90591750,90638350..90638513,90640637..90640738,90642956..90643106,90646128..90646194)
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AA seq
254 aa
AA seq
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MQVQCQQSPVLAGSATLVALGALVLYVAKPSGYGKHTESLKPAATRLPARAAWFLQELPS
FAVPAGILARQPLSLFGPPGTVLLGLFCVHYFHRTFMYSLLNRGRPYPAVLIFRGIAFCA
GNGFLQSYYLIYCAEYPDGWYTDIRFCLGVFLFILGMGVNIHSDYILRQLRKPGEITYRI
PKGGLFTYVSGANFLGEIIEWIGYALATWSLPALAFAFFSVCFLGLRAFHHHRFYLKMFE
DYPKSRKALIPFIF
NT seq
765 nt
NT seq
+upstream
nt +downstream
nt
atgcaggttcagtgccagcagagcccagtgctggcaggcagcgccactttggtcgccctt
ggggcactggtcttgtacgtcgcgaagccctccggctacgggaagcacacggagagcctg
aagcccgcggctacccgcctgccagcccgcgcagcctggttcctgcaggagctgccctcc
ttcgcggtgcccgcggggatcctcgctcggcagcccctctccctcttcgggccacctggg
acggtgcttctgggcctcttctgcgtacattacttccacaggacatttatgtactcactg
ctcaatcgagggaggccttatccagctgtactcattttccgaggcattgccttctgcgct
ggaaatggattccttcaaagctactatctgatttactgtgctgaataccctgatgggtgg
tacacagacatacggttttgcttgggtgtcttcttatttattttgggaatgggagtcaac
atccatagtgactatatattgcgccagctcaggaagcctggagaaatcacctacaggatt
ccaaaaggtggcttgtttacgtatgtttctggagccaatttccttggtgagatcattgaa
tggatcggctatgcgctggccacttggtccctcccagcacttgcatttgcatttttctca
gtttgtttccttgggctgcgagcttttcaccaccataggttctacctcaagatgtttgag
gactaccccaaatctcggaaagcccttattccattcatcttttaa
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