KEGG   Macaca fascicularis (crab-eating macaque): 102118853
Entry
102118853         CDS       T02918                                 
Symbol
ATIC
Name
(RefSeq) bifunctional purine biosynthesis protein ATIC
  KO
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
mcf00230  Purine metabolism
mcf00670  One carbon pool by folate
mcf01100  Metabolic pathways
mcf01523  Antifolate resistance
Module
mcf_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:mcf00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    102118853 (ATIC)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    102118853 (ATIC)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    102118853 (ATIC)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mcf04147]
    102118853 (ATIC)
Enzymes [BR:mcf01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     102118853 (ATIC)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     102118853 (ATIC)
Exosome [BR:mcf04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   102118853 (ATIC)
SSDB
Motif
Pfam: AICARFT_IMPCHas MGS Ribosomal_L12_N
Other DBs
NCBI-GeneID: 102118853
NCBI-ProteinID: XP_005574261
Ensembl: ENSMFAG00000044630
LinkDB
Position
12:join(111200034..111200052,111200376..111200502,111206080..111206156,111207584..111207650,111211846..111211934,111212898..111213049,111213733..111213889,111219854..111219979,111220815..111220922,111222033..111222118,111223142..111223231,111225882..111226010,111231855..111231947,111233833..111234015,111236191..111236346,111236623..111236742)
AA seq 592 aa
MAPGQLALFSVSDKTGLVEFARNLTSLGLNLVASGGTAKALRDAGLAVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARNIPEDNADMTRLDFNLIRVVACNLYPFVKTVASPGVTVEEA
VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVAVSTEMQSSESKDTSLETRRQLALKAFT
HTAQYDEAISDYFRRQYSKGISQMPLRYGMNPHQTPAQLYTLKPKLPITVLNGAPGFINL
CDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPIS
TAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYEEEALTILSKKKNG
NYCVLQMDQSYKPDENEVRTLFGLHLSQKRNNGVVDKSLFSNVVTKNKDLPESAVRDLIV
ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKT
GVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVEKLTEVSISSDA
FFPFRDNVDRAKRSGVAYIAAPAGSAADKVVIEACDELGIILAHTNLRLFHH
NT seq 1779 nt   +upstreamnt  +downstreamnt
atggctcctggccagctcgccttatttagtgtctctgacaaaaccggccttgtggaattt
gcaagaaacctgacctctcttggtttgaatctggtcgcttccggagggactgcaaaagct
ctcagggatgctggtctggcagtcagagatgtctccgagttgacgggatttcccgaaatg
ttggggggacgtgtgaaaactttgcatcctgcagtgcatgctggaatcctggctcgtaat
atcccagaagataatgctgacatgaccagacttgatttcaatcttataagagttgttgcc
tgcaatctctatccctttgtgaagacagtggcttctccaggtgtaactgttgaggaggct
gtggagcaaattgacattggtggagtaaccttactgagagctgcagccaaaaaccatgct
cgagtgacagtagtgtgtgaaccagaggactatgtggcagtgtccacggagatgcagagc
tccgagagtaaggacacctccttggagactagacgccagttagctttgaaggcattcact
catacggcacaatatgatgaagcaatttcagattatttcaggagacagtacagcaaaggc
atatctcagatgcccttgcgctatggaatgaaccctcatcagacccctgcccagctgtac
acactgaagcccaagcttcccatcacagttctaaatggagcccctggatttataaacttg
tgcgatgctttgaacgcctggcaactggtgaaggaactcaaggaggcgttaggtattcca
gccgctgcctctttcaaacatgtcagtccagcaggtgctgcggttggaattccactcagt
gaagatgaggccaaagtctgcatggtctatgatctctataaaaccctcacacccatctca
acggcatatgcaagagcaagaggggctgataggatgtcttcatttggtgattttgttgca
ctgtccgatgtttgtgatgtaccaactgcaaaaattatttccagagaagtatctgatggt
ataattgccccaggatatgaagaagaagctttgacaatactttccaaaaagaaaaatgga
aattactgtgtccttcagatggaccagtcttacaaaccagatgaaaatgaagttcgaact
ctcttcggtcttcatttaagccagaagagaaataatggtgtcgtcgacaagtcattattt
agcaatgttgttaccaagaataaagatttgccagagtcagccgtccgagacctcatcgta
gccaccattgctgtcaagtacactcagtctaactccgtgtgctacgccaagaatgggcag
gttatcggcattggagcaggacagcagtctcgtatacactgcactcgacttgcaggagat
aaggcaaactattggtggcttagacaccatccacaagtgctttcgatgaagtttaaaaca
ggagtgaagagagcagaaatctccaatgccatcgatcaatacgtgactggaaccattggc
gaggatgaagatttaatcaagtggaaggcattgtttgaggaagtccctgagttactcact
gaggcagagaagaaggaatgggttgagaaactgactgaagtttctatcagctctgatgcc
ttcttccctttcagagataacgtagacagagctaaaaggagtggtgtggcgtacattgcg
gctcccgccggttctgctgctgacaaagttgtgattgaagcctgcgacgaactgggaatc
atcctcgctcatacgaaccttcggctcttccaccactga

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