KEGG T02918: 102122757

Macaca fascicularis (crab-eating macaque): 102122757

Entry

102122757         CDS       T02918

Symbol

PDE10A

Name

(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1

K18438

cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35]

Organism

mcf Macaca fascicularis (crab-eating macaque)

Pathway

mcf00230

Purine metabolism

mcf01100

Metabolic pathways

mcf04024

cAMP signaling pathway

mcf05032

Morphine addiction

Brite

KEGG Orthology (KO) [BR:mcf00001]
09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    102122757 (PDE10A)
09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    102122757 (PDE10A)
09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    102122757 (PDE10A)
Enzymes [BR:mcf01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.17  3',5'-cyclic-nucleotide phosphodiesterase
     102122757 (PDE10A)
    3.1.4.35  3',5'-cyclic-GMP phosphodiesterase
     102122757 (PDE10A)

SSDB

Motif

Pfam:

PDEase_I GAF GAF_2 GAF_3 SpoVT_C HD DUF7334

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

Ensembl:

UniProt:

LinkDB

Position

4:join(5461538..5462411,5594480..5594608,5666418..5666446,5692401..5692521,5693885..5693934,5708708..5708848,5710615..5710770,5712185..5712235,5713618..5713676,5715253..5715304,5725396..5725538,5727882..5727974,5730457..5730643,5745785..5745927,5747164..5747247,5749563..5749713,5753903..5754058,5762619..5762791,5790658..5790769,5794888..5794968,5797723..5797811,5800655..5800757)

AA seq 1058 aa
MASPEEPLAPRPQGPPPAAGDEPGCGPGKLRLEPRRSAAGGGRAAGPGLAPEWPGRGRAE
RAAPPRPPPSSAGRASPAGGPGALSARGGGCGWVAARAPLALAFSSRVPSSSPSSFYFWP
PPPPPPPSFLPSSSAFHLPVRLPGREGAAAAAAAAGGGGDAGGGGGGRQEAAPLSVPTSS
SHRGGGGSGSGGGRRRLFLSPALQGLLLPARAGPRPPPPPRLPLGQAARRAGSPGFPGAG
PGGGGRTPRRPQGAGFALAAAAALLFGSDMEDGPSNNASCFRRLTECFLSPSLTDEKVKA
YLSLHPQVLDEFVSESVSAETVEKWLKRKNNKSEDESAPKEVSRYQDTNMQGVVYELNSY
IEQRLDTGGDNQLLLYELSSIIKIATKADGFALYFLGECNNSLCIFTPPGIKEGKPRLIP
AGPITQGTTISAYVAKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLCLPIVTAIGDLI
GILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYF
DNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIGEEKEGKPVFKKTKE
IRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGV
VQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSIC
TAEEWQGLMRFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRF
IMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHALFTDLERKGLLIACLCHDLDHRGFS
NTYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAII
ATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTAND
IYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPL
LKACRDNLNQWEKVIRGEETATWISSPSVAQKAAASED

NT seq 3177 nt +upstreamnt +downstreamnt
atggccagccccgaggagcctcttgctccccgcccccagggtcccccgccagcggcaggg
gacgagccgggctgcggccccggcaaactccgcctggaaccccggcgcagcgcggccggc
ggggggagagcggcgggcccgggcctggcccccgagtggcctggccgcggccgggccgag
cgcgccgcgcccccgcgcccgcccccctcctccgcaggccgcgccagcccagctgggggc
cccggcgccctctctgcgcgcggcggcggttgcggctgggtcgcggcccgcgctcccttg
gcgctcgccttctcctcccgggtcccctcctcctctccatcttccttttacttctggccg
ccgccccccccgccccctccctcttttctcccctcctcatctgcctttcacctccccgtg
cgtctcccaggaagggagggcgcagcggcggcggcggcggcggcgggaggaggcggcgat
gctggcggaggaggaggaggacgacaagaggcagctcccttgagcgtccccaccagcagt
agtcaccgcggcggcggtggcagcggcagcggcggcgggcggcggcggctcttcctctcg
cctgcgctccagggcttgcttctcccagcccgtgcagggccccggccgccgccgccgccc
cggctcccactcggccaggccgcccgccgcgcgggctcccccggcttccccggcgccggc
ccaggcggcggcggccgaactccgcggcgtccccagggcgccggcttcgccctcgccgcc
gcggccgcgctgctcttcggctccgacatggaagatggaccttctaataatgcgagctgc
ttccgaaggctgactgagtgcttcctgagccccagtttgacagatgaaaaagtgaaggca
tatctttctcttcacccccaggtattagatgaatttgtatctgaaagtgttagtgcagag
acagtagagaaatggctgaagaggaagaacaacaaatcagaagatgaatcggctcctaag
gaagtcagcaggtaccaagatacgaatatgcagggagttgtatatgaactaaacagctat
atagaacaacggttggacacaggaggagacaaccagctactcctctatgaactgagcagc
atcatcaaaatagccacaaaagctgatggatttgcattgtatttccttggagagtgcaat
aatagcctgtgcatattcacaccacctgggataaaggaaggaaaaccccgcctcatccct
gctgggcccatcactcagggcaccaccatctctgcttatgtggccaagtccaggaagaca
ttgctagtagaagacatccttggagatgagcgatttccaagaggtactggactggaatca
gggactcgtatccagtctgttctttgcttaccaattgtcactgcaattggtgacttgatt
ggtattcttgagctgtatcggcactggggcaaagaagccttctgtcttagtcaccaggag
gttgcaacagcaaatcttgcctgggcttcagtagcaatacatcaggtgcaggtatgcaga
ggccttgccaaacagactgaattgaatgactttctactcgacgtatcaaaaacatatttt
gataacatagttgcaatagattctctacttgaacacataatgatatatgcaaaaaacctg
gtgaatgccgaccgttgtgcacttttccaggtagaccataagaacaaggagttatattca
gacctttttgatattggagaggaaaaggaaggaaaacccgtcttcaagaagaccaaagag
ataagattttcaattgagaaaggaattgctggccaagtagcaagaacaggggaagtcctg
aacattccagatgcctatgcagacccacgctttaacagagaagtagacttgtacacaggc
tacaccacgcggaacatcctgtgcatgcccatcgtcagccgaggcagcgtgataggtgtg
gtgcagatggtcaacaaaatcagtggcagtgccttctctaaaaccgatgaaaacaacttc
aaaatgtttgccgtcttttgtgctttagccttacactgtgctaatatgtatcatagaatt
cgccactcagagtgcatttaccgggtaacaatggaaaagctgtcctaccatagcatttgt
actgcagaagagtggcaaggcctcatgcgatttacccttcctgtgcgtctctgcaaagaa
attgaattattccactttgacattggtccttttgaaaacatgtggcctggaatttttgtc
tacatggttcatcggtcctgtgggacatcctgctttgagctcgaaaagttgtgtcgtttt
attatgtctgtgaagaagaactatcggcgggttccttatcacaactggaagcatgcggtc
actgtagcacactgcatgtacgccatacttcagaacaaccacgcgcttttcacagacctt
gagcgcaaaggactgctgatcgcgtgtctgtgtcatgacctagaccacagaggcttcagt
aacacctacctgcagaagttcgaccaccctctagcagctctctactccacttccaccatg
gagcagcaccacttctcccagaccgtgtccatcctccagctggaagggcacaatatcttc
tccactctgagctccagtgaatacgagcaggtgcttgagatcatccgcaaagccatcatt
gccacagaccttgctttatactttggaaacaggaaacagttggaagagatgtaccagacg
ggatcgctaaaccttaataatcaatcacacagagaccgtgtaattggtttgatgatgact
gcctgtgacctttgttctgtgacaaaactgtggcccgttacaaaattgacggcaaatgat
atatatgcagaattctgggctgagggtgatgaaatgaagaaattgggaatacagcctatt
cctatgatggacagagacaagaaggatgaagtcccccaaggccagcttgggttctacaat
gccgtagccattccctgctatacaacccttacccagatcctccctcccacggagcctctc
cttaaagcatgcagggataatctcaatcagtgggagaaggtgattcgaggggaggagact
gcaacctggatttcatccccgtccgtggctcagaaggcagctgcatctgaagattga

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