KEGG   Macaca fascicularis (crab-eating macaque): 102125039
Entry
102125039         CDS       T02918                                 
Symbol
HDAC1
Name
(RefSeq) histone deacetylase 1 isoform X1
  KO
K06067  histone deacetylase 1/2 [EC:3.5.1.98]
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
mcf03082  ATP-dependent chromatin remodeling
mcf03083  Polycomb repressive complex
mcf04110  Cell cycle
mcf04213  Longevity regulating pathway - multiple species
mcf04330  Notch signaling pathway
mcf04350  TGF-beta signaling pathway
mcf04613  Neutrophil extracellular trap formation
mcf04919  Thyroid hormone signaling pathway
mcf05016  Huntington disease
mcf05031  Amphetamine addiction
mcf05034  Alcoholism
mcf05165  Human papillomavirus infection
mcf05169  Epstein-Barr virus infection
mcf05200  Pathways in cancer
mcf05202  Transcriptional misregulation in cancer
mcf05203  Viral carcinogenesis
mcf05206  MicroRNAs in cancer
mcf05220  Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:mcf00001]
 09120 Genetic Information Processing
  09126 Chromosome
   03082 ATP-dependent chromatin remodeling
    102125039 (HDAC1)
   03083 Polycomb repressive complex
    102125039 (HDAC1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    102125039 (HDAC1)
   04350 TGF-beta signaling pathway
    102125039 (HDAC1)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    102125039 (HDAC1)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    102125039 (HDAC1)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    102125039 (HDAC1)
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    102125039 (HDAC1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102125039 (HDAC1)
   05202 Transcriptional misregulation in cancer
    102125039 (HDAC1)
   05206 MicroRNAs in cancer
    102125039 (HDAC1)
   05203 Viral carcinogenesis
    102125039 (HDAC1)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    102125039 (HDAC1)
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    102125039 (HDAC1)
   05165 Human papillomavirus infection
    102125039 (HDAC1)
  09164 Neurodegenerative disease
   05016 Huntington disease
    102125039 (HDAC1)
  09165 Substance dependence
   05031 Amphetamine addiction
    102125039 (HDAC1)
   05034 Alcoholism
    102125039 (HDAC1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mcf03036]
    102125039 (HDAC1)
Enzymes [BR:mcf01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.98  histone deacetylase
     102125039 (HDAC1)
Chromosome and associated proteins [BR:mcf03036]
 Eukaryotic type
  Histone modification proteins
   HDACs (histone deacetylases)
    Class I HDACs
     102125039 (HDAC1)
   HDAC complexes
    Sin3A-HDAC complex
     102125039 (HDAC1)
    BRAF-HDAC complex
     102125039 (HDAC1)
    REST complex
     102125039 (HDAC1)
    SHIP complex
     102125039 (HDAC1)
    MiDAC complex
     102125039 (HDAC1)
   Polycomb repressive complex (PRC) and associated proteins
    Noncanonical PRC1 (PRC1.6)
     102125039 (HDAC1)
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    102125039 (HDAC1)
  Chromatin remodeling factors
   NuRD complex
    102125039 (HDAC1)
SSDB
Motif
Pfam: Hist_deacetyl
Other DBs
NCBI-GeneID: 102125039
NCBI-ProteinID: XP_005544162
Ensembl: ENSMFAG00000001093
UniProt: A0A2K5U8T1
LinkDB
Position
1:complement(join(202689402..202689429,202689699..202689747,202690206..202690358,202690638..202690768,202690862..202690970,202691538..202691678,202691760..202691868,202693615..202693707,202695103..202695244,202695703..202695841,202698856..202698930,202707683..202707800,202724368..202724480,202733081..202733129))
AA seq 482 aa
MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKAN
AEEMTKYHSDDYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAS
AVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHG
DGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDESYEAI
FKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCFNLTIKGHAKCVEFVKSFNLPMLMLGG
GGYTIRNVARCWTYETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTNEYLE
KIKQRLFENLRMLPHAPGVQMQAIPEDAIPEESGDEDEEDPDKRISICSSDKRIACEEEF
SDSEEEGEGGRKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEKPEAKGVKEEVK
LA
NT seq 1449 nt   +upstreamnt  +downstreamnt
atggcgcagacgcagggcacccggaggaaagtctgttactactacgacggggatgttgga
aattactactacggacaaggccacccaatgaagcctcaccgaatccgcatgactcataat
ttgctgctcaactatggtctctaccgaaaaatggaaatctatcgccctcacaaagccaat
gctgaggagatgaccaagtaccatagtgacgactacattaaattcttgcgctccatccgt
ccagataacatgtcggagtacagcaagcagatgcagagattcaacgttggtgaggactgt
ccagtattcgacggcctgtttgagttctgtcagttgtctactggtggttctgtggcaagt
gctgtgaaacttaataagcagcagacggacatcgctgtgaattgggctgggggcctgcac
catgcaaagaagtctgaggcatctggcttctgttacgtcaatgatatcgtcttggccatc
ctggaactgctaaagtatcaccagagggtgctgtatattgacattgatattcaccatggc
gacggcgtggaagaggccttctataccacagaccgggtcatgactgtgtcctttcataag
tatggagagtacttcccaggaactggggacctgcgggatatcggggctggaaaaggcaag
tattatgctgttaactacccgctccgagacgggattgatgacgagtcctatgaggccatt
ttcaagccggtcatgtccaaagtaatggagatgttccaacctagcgcggtggtcttacag
tgtggctcagactccctgtctggggatcggttaggttgcttcaatctaaccatcaaaggg
cacgccaagtgtgtggaatttgtcaagagctttaacctgcctatgctgatgctgggaggt
ggtggttacaccattcgtaatgttgcccggtgctggacatacgagacagctgtggccctg
gatacggagatccctaatgagcttccatacaacgactactttgaatactttggaccggat
ttcaagctccacatcagtccttccaatatgactaaccagaacacgaatgagtacctggag
aagatcaaacagcggctgtttgagaaccttagaatgctgccgcatgcacctggggtccaa
atgcaggcgattcctgaggacgccatccctgaggagagtggcgatgaggacgaagaagac
cctgacaagcgcatctcgatctgctcctccgacaaacgaattgcctgtgaggaagagttc
tccgattctgaagaggagggagaggggggccgcaagaactcttccaacttcaaaaaagcc
aagagagtcaaaacagaggatgaaaaagagaaagacccagaggagaagaaagaagtcaca
gaagaggagaaaaccaaggaggaaaagccagaagccaaaggggtcaaggaggaggtcaag
ttggcctga

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