KEGG T02918: 102126003

Macaca fascicularis (crab-eating macaque): 102126003

Entry

102126003         CDS       T02918

Symbol

SDHA

Name

(RefSeq) succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial isoform X2

K00234

succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1]

Organism

mcf Macaca fascicularis (crab-eating macaque)

Pathway

mcf00020

Citrate cycle (TCA cycle)

mcf00190

Oxidative phosphorylation

mcf01100

Metabolic pathways

mcf01200

Carbon metabolism

mcf04714

Thermogenesis

mcf04932

Non-alcoholic fatty liver disease

mcf05010

Alzheimer disease

mcf05012

Parkinson disease

mcf05014

Amyotrophic lateral sclerosis

mcf05016

Huntington disease

mcf05020

Prion disease

mcf05022

Pathways of neurodegeneration - multiple diseases

mcf05208

Chemical carcinogenesis - reactive oxygen species

mcf05415

Diabetic cardiomyopathy

Module

mcf_M00009

Citrate cycle (TCA cycle, Krebs cycle)

mcf_M00011

Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate

mcf_M00148

Succinate dehydrogenase (ubiquinone)

Brite

KEGG Orthology (KO) [BR:mcf00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    102126003 (SDHA)
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    102126003 (SDHA)
09150 Organismal Systems
  09159 Environmental adaptation
   04714 Thermogenesis
    102126003 (SDHA)
09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    102126003 (SDHA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102126003 (SDHA)
   05012 Parkinson disease
    102126003 (SDHA)
   05014 Amyotrophic lateral sclerosis
    102126003 (SDHA)
   05016 Huntington disease
    102126003 (SDHA)
   05020 Prion disease
    102126003 (SDHA)
   05022 Pathways of neurodegeneration - multiple diseases
    102126003 (SDHA)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    102126003 (SDHA)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    102126003 (SDHA)
Enzymes [BR:mcf01000]
1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.5  With a quinone or related compound as acceptor
    1.3.5.1  succinate dehydrogenase
     102126003 (SDHA)

SSDB

Motif

Pfam:

FAD_binding_2 Succ_DH_flav_C Thi4 Pyr_redox_2 DAO GIDA HI0933_like FAD_binding_3

Other DBs

NCBI-GeneID:

102126003

NCBI-ProteinID:

XP_045250642

LinkDB

Position

6:join(547794..547856,552913..552999,553728..553889,554792..554935,555256..555420,557530..557678,560811..560935,563528..563696,565541..565736,567132..567303,571680..571798,575130..575241,575468..575598,577571..577684,579546..579632)

AA seq 664 aa
MSGVRRLSRLLSTRRLALAKAWPAVLQTGTRGFHFTVDGNKRASAKVSDSISAQYPVVDH
EFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNWR
WHFYDTVKGSDWLGDQDAIHYMTEQAPAAVVELENYGMPFSRTEDGKIYQRAFGGQSLKF
GKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMEDGECRGVIALCIE
DGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMITRAGLPCQDLEFVQFHPTGI
YGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPE
KDHVYLQLHHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQ
VLRHVNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIEESCRPGDK
VPPIKPNAGEESVMNLDKLRFADGSIRTSELRLSMQKSMQNHAAVFRVGSVLQEGCGKIS
KLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVR
IDEYDYSKPIQGQQKKPFEEHWRKHTLSYVDVSTGKVTLEYRPVIDKTLNEADCATVPPA
IRSY

NT seq 1995 nt +upstreamnt +downstreamnt
atgtcgggggtccggagactgtcgcggctgctgagcactcggcgcctggcgctggccaag
gcgtggccagcagtgttgcaaacaggaacccgaggttttcacttcactgttgatgggaac
aagagggcatctgctaaagtttcagattccatttctgctcagtatccagtagtggatcat
gaatttgatgcggtggtggtaggcgctggaggggcaggcttgcgagctgcatttggcctt
tctgaggcagggtttaatacagcatgtgttacaaagctgtttcctaccaggtcacacact
gttgcggcacagggaggaatcaacgctgctctggggaacatggaggaggacaactggagg
tggcatttctacgacaccgtgaagggctccgactggctgggggaccaggatgccatccac
tacatgacagagcaggctcctgccgccgtggtcgagctggaaaattacggcatgccgttt
agcagaactgaagatgggaagatttatcagcgtgcatttggtggacagagcctcaagttt
ggaaagggcgggcaggcccatcggtgctgctgtgtggctgatcggaccggccactcacta
ttgcacaccttatatggaaggtctctgcgatacgataccagctattttgtggagtatttt
gccttggatctcctgatggaggacggggagtgccgtggtgtcatcgcactgtgcatagag
gacgggtccatccatcgcataagagcaaagaacactgttgttgccacaggaggctacggg
cgcacctacttcagctgcacgtctgcccacaccagcaccggcgacggcacggccatgatc
accagggcaggccttccttgccaggacctagagttcgttcagttccaccccacaggcata
tatggtgccggttgtctcattacggaaggatgtcgtggagagggaggcattctcattaac
agtcaaggcgaaaggtttatggagcgatacgcccccgtggcgaaggacctggcgtctaga
gatgtggtgtctcggtcgatgactctggagatccgcgaaggaagaggctgtggccctgag
aaagatcacgtctacctgcagctgcaccacctgcctccggagcagctggccacgcgcctg
cccggcatttcagagacagccatgatcttcgctggtgtggacgtcacgaaggagccgatc
cctgtcctccccaccgtgcattataacatgggcggcattcccaccaactacaagggtcag
gtcctgaggcacgtgaatggccaggatcagattgtgcccgggctgtacgcctgtggggag
gccgcctgtgcctcggtacatggtgccaaccggctcggggcaaactccctcttggacctg
gtcgtctttggtcgggcatgtgccctgagcatcgaagagtcgtgcaggcctggagataaa
gtccctccaattaaaccaaatgctggagaagaatctgtcatgaatcttgacaaattgaga
tttgctgacggaagcataagaacgtcagaacttcgactcagcatgcagaagtcaatgcaa
aatcatgctgccgtgttccgtgtgggaagcgtgttgcaagaaggttgtgggaaaatcagc
aagctctacggagacctgaagcacctgaagacgtttgaccggggaatggtctggaacacg
gacctggtggagaccctggagctgcagaacctgatgctgtgtgcgctgcagaccatctac
ggagcagaggcgcggaaggagtcacggggcgcacacgccagggaagactacaaggtgcgg
attgatgagtacgattactccaagcccatccaggggcaacagaagaagccttttgaggag
cactggaggaagcacaccctgtcctatgtggacgtcagcactgggaaggtcactctggaa
tatagacccgtaatcgacaaaactttgaacgaggctgactgtgccaccgtccccccagcc
attcgctcctactga

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