KEGG   Macaca fascicularis (crab-eating macaque): 102132595
Entry
102132595         CDS       T02918                                 
Symbol
ITGB4
Name
(RefSeq) integrin beta-4 isoform X10
  KO
K06525  integrin beta 4
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
mcf04151  PI3K-Akt signaling pathway
mcf04382  Cornified envelope formation
mcf04510  Focal adhesion
mcf04512  ECM-receptor interaction
mcf04518  Integrin signaling
mcf04810  Regulation of actin cytoskeleton
mcf04820  Cytoskeleton in muscle cells
mcf05165  Human papillomavirus infection
mcf05410  Hypertrophic cardiomyopathy
mcf05412  Arrhythmogenic right ventricular cardiomyopathy
mcf05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mcf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    102132595 (ITGB4)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    102132595 (ITGB4)
   04518 Integrin signaling
    102132595 (ITGB4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102132595 (ITGB4)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    102132595 (ITGB4)
   04810 Regulation of actin cytoskeleton
    102132595 (ITGB4)
 09150 Organismal Systems
  09158 Development and regeneration
   04382 Cornified envelope formation
    102132595 (ITGB4)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    102132595 (ITGB4)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    102132595 (ITGB4)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    102132595 (ITGB4)
   05414 Dilated cardiomyopathy
    102132595 (ITGB4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mcf04147]
    102132595 (ITGB4)
   04515 Cell adhesion molecules [BR:mcf04515]
    102132595 (ITGB4)
   04090 CD molecules [BR:mcf04090]
    102132595 (ITGB4)
Exosome [BR:mcf04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   102132595 (ITGB4)
  Exosomal proteins of bladder cancer cells
   102132595 (ITGB4)
Cell adhesion molecules [BR:mcf04515]
 Integrins
  Integrin beta subunits
   102132595 (ITGB4)
CD molecules [BR:mcf04090]
 Proteins
  102132595 (ITGB4)
SSDB
Motif
Pfam: Integrin_beta fn3 Calx-beta Integrin_B_tail Pur_ac_phosph_N I-EGF_1 EGF_Teneurin FN3_DSCAM-DSCAML_C PSI_integrin EGF_integrin EGF_TEN EGF_2 vWA_SIBA-E SEA
Other DBs
NCBI-GeneID: 102132595
NCBI-ProteinID: XP_005585030
Ensembl: ENSMFAG00000001695
UniProt: A0A2K5TWI7
LinkDB
Position
16:join(82126546..82126624,82129407..82129489,82129616..82129717,82129863..82130067,82130590..82130686,82131787..82131958,82133022..82133285,82133672..82133761,82134045..82134167,82134607..82134771,82134961..82135037,82135972..82136174,82139034..82139137,82139267..82139365,82139545..82139674,82140304..82140426,82140518..82140624,82143016..82143049,82143226..82143417,82143704..82143807,82144143..82144201,82144333..82144356,82145682..82145830,82145920..82146099,82147036..82147184,82152205..82152409,82153786..82153943,82154365..82154545,82154656..82154793,82156192..82156374,82156464..82156595,82158593..82158832,82159044..82159202,82159697..82159846,82160709..82160897,82160984..82161139,82161222..82161386,82161480..82161590,82161696..82161835)
AA seq 1806 aa
MAGPRPSPWARLLLAALISISLSGTLANRCKKAPVKSCTECVRVDKDCAYCTDEMFRDRR
CNTQAELLAAGCQRESIVVMESSFQITEETQIDTTLRRSQMSPQGLRVRLRPGEERHFEL
EVFEPRESPVDLYILMDFSNSMSDDLDNLKKMGQNLAQVLSQLTSDYTIGFGKFVDKVSV
PQTDMRPEKLKEPWPNSDPPFSFKNVISLTEDVDEFRNKLQGERISGNLDAPEGGFDAIL
QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMSRNDERCHLDATGTYTQYR
TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVELLE
EAFNRIRSNLDIRALDSPRGFRTEVTSKMFQKMKTGSFQIQRGEVGIYQVQLRAIEHVDG
THVCQLPKEDQKGNIHLKPSFSDGLKMDAGIICDVCPCELQKEVRSARCNFNGDFMCGQC
VCSEGWSGQTCNCSTGSLSDIQPCLREGEDKPCSGRGECQCGHCVCYGEGRYEGQFCEYD
NFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGPSCDCPLSNATCIDSNGGICNGRGHCECG
RCHCHQQSLYTDTICEINYSAIHPGLCEDLRSCVQCQAWGTGEKKGRTCEECNFKVKMVD
ELKRAEEVVVRCSFRDEDDDCTYSYTMEGDGAPGPNSTVLVHKKKDCPPSSFWWLIPLLL
LLLPLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPML
RSGNLKGRDVVRWKVTNNVQRPGFATHAASINPTELVPYGLSLRLARLCTENLLKPDTRE
CAQLRQEVEENLNEVYRQISGVHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKPALL
KLTEKQVEQRAFHDLKVAPGYYTLTADQDARGMVEFQEGVELVDVRVPLFIRPEDDEEKQ
LLVEAIDVPAGTATLGRRLVNITIIKEQARDVVSFEQPEYSVSRGDQVARIPVIRRVLDG
GKSQVSYRTQDGTAQGNRDYIPVEGELLFQPGEAWKELQVKLLELEEVDSLLRGRQIRRF
HVQLSNPKFGAHLGQPHSTTIIIRDPDELDRSLTSQMVSSQPPSHGDLGAPQNPNAKAAG
SRKIHFNWLPPSGKPMGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAY
GAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGL
VNDDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQ
PKRPMSIPIIPDIPIVDAQSGEDYDSFLMYSDDVLRSPSGSQRPSVSDDTEHLVNGRMDF
AFPGSANSLHRMTTTGAAAYGTHLSPHVPHRGLSTSSTLTRDYHSLTRSEHSHSTTLPRD
YSTLTSVSSHGLPPIWEHGRSRLPLSWALGSRSRAQMKGFPPSRGPRDSIILAGRPAAPS
WGPDSRLTAGVPDTPTRLVFSALGPTSLRVSWQEPRCERPLQGYSVEYQLLNGGELHRLN
IPNPAQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPGSAF
TLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDIVGYLVTCEMAQGGGPATTFRVDGDS
PESRLTVPGLSENVPYKFKVQARTTEGFGPEREGIITIESQDGGPFPQLGSHAGLFQHPL
QSEYSSITTTHTSATEPFLVDGLTLGAQHLEAGGSLTRHVTQEFVSRTLTTSGTLSTQVD
QQFFQT
NT seq 5421 nt   +upstreamnt  +downstreamnt
atggcagggccacgccccagcccatgggccaggctgctactggcagccttgatcagcatc
agcctctctgggaccttggcaaaccgctgcaagaaggccccagtgaagagctgcacggag
tgtgtccgtgtggataaggactgcgcctactgcacggacgagatgttcagggaccggcgc
tgcaacacccaggcggagctgctggccgcaggctgtcagcgcgagagcatcgtggtcatg
gagagcagcttccagattacagaggagacccagattgacaccaccctgcggcgcagccag
atgtccccccagggcctgcgggtccggctgcggcccggtgaggagcggcactttgagctg
gaggtgtttgagccccgggagagccccgtggacctgtacatcctcatggacttctccaac
tccatgtccgatgatctggacaacctcaagaagatggggcagaacttggctcaggtcctg
agccagctcaccagtgactacactattggatttggcaagtttgtggacaaagtcagcgtc
ccgcagacagacatgaggcctgagaagctgaaggagccctggcccaacagtgaccccccc
ttctccttcaagaacgtcatcagcctgacagaagatgtggatgagttccggaataaactg
cagggggagaggatctcaggcaacctggatgctcctgagggcggcttcgatgccatcctg
cagacggccgtgtgcacgagggacattggctggcgcccggacagcacccacctgctggtc
ttctccaccgagtcggccttccactatgaggctgacggtgccaatgtgctggctggcatc
atgagccgcaacgatgaacggtgccacctggacgccacgggcacctacacccagtacagg
acacaggactacccgtcggtgcccaccctggtgcgcctgctcgcaaagcacaacatcatc
cctatctttgctgtcaccaactactcctacagctactacgagaagcttcacacctatttc
cctgtctcctcgctgggggtgctgcaggaggactcgtccaacatcgtggagctgctggag
gaggccttcaatcgaatccgctccaacctggacatccgggccctagacagcccccgaggc
tttcggacagaggtcacctccaagatgttccagaagatgaagactgggtcctttcagatc
cagcggggggaagtgggcatataccaggtgcagctgcgggccattgagcacgtggatggg
acgcacgtgtgccagctgccgaaggaggaccagaagggcaacatccatctgaaaccttcc
ttctctgatggcctcaagatggacgcgggcatcatctgtgatgtgtgcccctgcgagctg
caaaaagaggtgcggtcagctcgctgcaacttcaatggagacttcatgtgtggacagtgt
gtgtgcagtgagggctggagtggccagacctgcaactgctccaccggctctctgagtgac
attcagccctgcctgcgggagggtgaggacaagccatgctcgggccgtggggagtgccag
tgcgggcactgtgtgtgctacggcgaaggccgctacgagggtcagttctgcgagtatgac
aacttccagtgtccccgcacttctgggttcctctgcaatgaccgaggacgctgctccatg
ggccagtgtgtgtgtgagcctggttggacaggcccaagctgtgactgtcccctcagcaat
gccacctgcatcgacagcaatgggggcatctgtaatggacgtggccactgtgagtgtggc
cgctgccactgccaccagcagtcgctttacacggacaccatctgcgagatcaactactca
gcgatccacccgggcctctgcgaggacctacgctcctgcgtgcagtgccaggcatggggc
accggggagaagaaggggcgcacgtgtgaggaatgcaacttcaaggtcaagatggtggac
gagcttaagagagccgaggaggtggtggtgcgctgctccttccgggacgaggacgatgac
tgcacctacagctacaccatggaaggcgacggcgcccctgggcccaacagcaccgtcctg
gtgcacaagaagaaggactgccctcccagctccttctggtggctcatccccctgctcctc
ctcctcctgccgctcctggccctgctgctgctgctctgctggaagtactgcgcctgctgc
aaggcctgcctggcacttctcccttgctgcaaccgaggtcacatggtgggctttaaggaa
gaccactacatgctgcgggagaacctgatggcctcagaccacctggacacgcccatgctg
cgcagcgggaacctcaagggccgtgacgtggtccgctggaaggtcaccaacaacgtgcag
cggcctggctttgccactcatgccgccagcatcaaccccacagaactggtgccctacggg
ctgtccttgcgcctggcccgcctttgcaccgagaacctgctaaagcctgacactcgggag
tgtgcccagctgcgccaggaggtggaggagaacctgaacgaagtctacaggcagatctcc
ggtgtacacaagctccagcagaccaagttccggcagcagcccaatgctgggaaaaagcaa
gaccacaccattgtggacacagtgctgatggcgccccgctcggccaagccggccctgctg
aagcttacagagaagcaggtggaacagagggcctttcatgacctcaaggtggcccccggc
tactacaccctcactgcagaccaggacgcccggggcatggtggagttccaggagggtgtg
gagctggtggacgtacgggtgcccctctttatccggcctgaggacgacgaggagaagcag
ctgctggtggaggccatcgatgtacctgcgggcactgccacccttggccgccgcctggta
aacatcaccatcatcaaggagcaagccagagatgtggtgtcctttgagcagcctgagtac
tcggtcagccgtggggaccaggtggctcgcatccctgtcatccggcgcgtcctggacggc
gggaagtctcaggtctcctaccgcacgcaggatggcactgcacagggcaaccgggactac
atccctgtggagggtgagctgctgttccagcctggagaggcctggaaagagctgcaggtg
aagctcctggagctggaagaggtcgactcccttctgcggggccgccagatccgccgtttc
cacgtacagctcagcaaccctaagtttggggcccacctgggccagccccactccaccacc
atcatcatcagggacccagatgagctggaccggagcctcacgagtcagatggtgtcatca
cagccaccctctcacggtgacctgggcgccccgcagaaccccaacgctaaggccgctggg
tccaggaagatccatttcaactggctgcccccttctggcaagccaatggggtacagggta
aagtactggattcagggtgactctgagtccgaagcccacctgctcgacagcaaggtgccc
tcagtggagctcaccaacctgtacccgtattgcgactatgagatgaaggtgtgcgcctac
ggggctcagggcgagggaccctacagctccctagtgtcctgccgcacccaccaggaagtg
cccagcgagccagggcgtctggccttcaatgtcgtctcctccacggtgacccagctgagc
tgggccgagccggctgagaccaacggtgagatcacagcctacgaggtctgctatggcctg
gtcaacgacgacaaccgacctatcgggcccatgaagaaggtgctggttgacaatcctaag
aaccggatgctgctcattgagaaccttcgggagtcccagccctaccgctacacggtgaag
gcgcgcaacggggccggctgggggcccgagcgggaggccatcatcaacctggccacccaa
cccaagcggcccatgtccatccccatcatccctgacatccccatcgtggacgcccagagc
ggggaggactacgacagcttccttatgtacagcgatgatgttctacgctctccatctggc
agccagaggcccagcgtctctgatgacaccgagcacctagtgaatggccggatggacttt
gccttcccgggcagtgccaactccctgcacaggatgaccacgaccggtgccgctgcctat
ggaacccacctgagcccccacgtgccccaccgcggactaagcacatcctccaccctcaca
cgggactaccactcgctgacccgctcagaacactcacactcgaccacactgcccagggac
tactccaccctcacctccgtctcctcccacggcctccctcccatctgggaacacgggagg
agcaggcttccgctgtcctgggctctggggtcccggagtcgggctcagatgaaagggttc
cccccttccaggggcccacgagactctataatcctggctgggaggccagcagcgccctcc
tggggcccagactctcgcctgaccgctggtgtgcccgacacgcccacccgcctggtattc
tctgccctgggacccacatctctcagagtgagctggcaggagccacggtgcgagcggccg
ctgcagggctacagcgtggagtaccagctgctgaacggcggcgagctacatcggctcaac
atccccaaccctgcccagacctcggtggtggtggaagacctcctgcccaaccactcctat
gtgttccgcgtgcgggcccagagccaggaaggctggggccgagagcgtgagggtgtcatc
accatcgaatcccaggtgcacccgcagagcccactctgtcccctgccaggctccgccttc
actttgagcactcccagcgccccaggtccgctggtgttcactgccctgagcccagactcg
ctgcagctgagctgggagcggccacggaggcccaatggggatatcgtcggctacctggtg
acctgtgagatggcccaaggaggagggccagccactacattccgggtggatggcgacagc
cccgagagccggctgaccgtgccgggcctcagcgagaacgtgccctacaagttcaaggtg
caggccaggaccactgagggcttcgggccagagcgcgagggcatcatcaccatagagtcc
caggatggaggccccttcccacagctgggcagccatgccgggctcttccagcacccactg
caaagtgagtacagcagcatcaccaccacccacaccagcgccaccgagcccttcctagtg
gatgggctgaccctgggggcccagcacctggaggcaggcggctccctcacccggcatgtg
acccaggagtttgtgagccggacgctgaccaccagcggaaccctcagcacccaggtggac
caacagttcttccaaacctga

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