KEGG   Macaca fascicularis (crab-eating macaque): 102133756
Entry
102133756         CDS       T02918                                 
Symbol
GSK3B
Name
(RefSeq) glycogen synthase kinase-3 beta isoform X1
  KO
K03083  glycogen synthase kinase 3 beta [EC:2.7.11.26]
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
mcf01521  EGFR tyrosine kinase inhibitor resistance
mcf04012  ErbB signaling pathway
mcf04062  Chemokine signaling pathway
mcf04110  Cell cycle
mcf04150  mTOR signaling pathway
mcf04151  PI3K-Akt signaling pathway
mcf04310  Wnt signaling pathway
mcf04340  Hedgehog signaling pathway
mcf04360  Axon guidance
mcf04390  Hippo signaling pathway
mcf04510  Focal adhesion
mcf04517  IgSF CAM signaling
mcf04518  Integrin signaling
mcf04550  Signaling pathways regulating pluripotency of stem cells
mcf04657  IL-17 signaling pathway
mcf04660  T cell receptor signaling pathway
mcf04662  B cell receptor signaling pathway
mcf04722  Neurotrophin signaling pathway
mcf04728  Dopaminergic synapse
mcf04910  Insulin signaling pathway
mcf04916  Melanogenesis
mcf04917  Prolactin signaling pathway
mcf04919  Thyroid hormone signaling pathway
mcf04931  Insulin resistance
mcf04932  Non-alcoholic fatty liver disease
mcf04934  Cushing syndrome
mcf04935  Growth hormone synthesis, secretion and action
mcf04936  Alcoholic liver disease
mcf05010  Alzheimer disease
mcf05020  Prion disease
mcf05022  Pathways of neurodegeneration - multiple diseases
mcf05135  Yersinia infection
mcf05160  Hepatitis C
mcf05162  Measles
mcf05163  Human cytomegalovirus infection
mcf05165  Human papillomavirus infection
mcf05167  Kaposi sarcoma-associated herpesvirus infection
mcf05200  Pathways in cancer
mcf05210  Colorectal cancer
mcf05213  Endometrial cancer
mcf05215  Prostate cancer
mcf05217  Basal cell carcinoma
mcf05224  Breast cancer
mcf05225  Hepatocellular carcinoma
mcf05226  Gastric cancer
mcf05415  Diabetic cardiomyopathy
mcf05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mcf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    102133756 (GSK3B)
   04310 Wnt signaling pathway
    102133756 (GSK3B)
   04340 Hedgehog signaling pathway
    102133756 (GSK3B)
   04390 Hippo signaling pathway
    102133756 (GSK3B)
   04151 PI3K-Akt signaling pathway
    102133756 (GSK3B)
   04150 mTOR signaling pathway
    102133756 (GSK3B)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    102133756 (GSK3B)
   04518 Integrin signaling
    102133756 (GSK3B)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    102133756 (GSK3B)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102133756 (GSK3B)
   04550 Signaling pathways regulating pluripotency of stem cells
    102133756 (GSK3B)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    102133756 (GSK3B)
   04657 IL-17 signaling pathway
    102133756 (GSK3B)
   04662 B cell receptor signaling pathway
    102133756 (GSK3B)
   04062 Chemokine signaling pathway
    102133756 (GSK3B)
  09152 Endocrine system
   04910 Insulin signaling pathway
    102133756 (GSK3B)
   04917 Prolactin signaling pathway
    102133756 (GSK3B)
   04935 Growth hormone synthesis, secretion and action
    102133756 (GSK3B)
   04919 Thyroid hormone signaling pathway
    102133756 (GSK3B)
   04916 Melanogenesis
    102133756 (GSK3B)
  09156 Nervous system
   04728 Dopaminergic synapse
    102133756 (GSK3B)
   04722 Neurotrophin signaling pathway
    102133756 (GSK3B)
  09158 Development and regeneration
   04360 Axon guidance
    102133756 (GSK3B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102133756 (GSK3B)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102133756 (GSK3B)
   05225 Hepatocellular carcinoma
    102133756 (GSK3B)
   05226 Gastric cancer
    102133756 (GSK3B)
   05217 Basal cell carcinoma
    102133756 (GSK3B)
   05215 Prostate cancer
    102133756 (GSK3B)
   05213 Endometrial cancer
    102133756 (GSK3B)
   05224 Breast cancer
    102133756 (GSK3B)
  09172 Infectious disease: viral
   05160 Hepatitis C
    102133756 (GSK3B)
   05162 Measles
    102133756 (GSK3B)
   05163 Human cytomegalovirus infection
    102133756 (GSK3B)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102133756 (GSK3B)
   05165 Human papillomavirus infection
    102133756 (GSK3B)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    102133756 (GSK3B)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102133756 (GSK3B)
   05020 Prion disease
    102133756 (GSK3B)
   05022 Pathways of neurodegeneration - multiple diseases
    102133756 (GSK3B)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102133756 (GSK3B)
   05415 Diabetic cardiomyopathy
    102133756 (GSK3B)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    102133756 (GSK3B)
   04932 Non-alcoholic fatty liver disease
    102133756 (GSK3B)
   04931 Insulin resistance
    102133756 (GSK3B)
   04934 Cushing syndrome
    102133756 (GSK3B)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102133756 (GSK3B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mcf01001]
    102133756 (GSK3B)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mcf03036]
    102133756 (GSK3B)
Enzymes [BR:mcf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.26  tau-protein kinase
     102133756 (GSK3B)
Protein kinases [BR:mcf01001]
 Serine/threonine kinases: CMGC group
  GSK family [OT]
   102133756 (GSK3B)
Chromosome and associated proteins [BR:mcf03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    102133756 (GSK3B)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kinase-like Kdo APH
Other DBs
NCBI-GeneID: 102133756
NCBI-ProteinID: XP_005548108
Ensembl: ENSMFAG00000002620
LinkDB
Position
2:join(163087739..163087826,163179500..163179693,163230757..163230840,163254305..163254415,163263156..163263286,163266494..163266600,163273365..163273462,163301834..163301929,163311686..163311724,163314344..163314530,163334211..163334309,163350995..163351062)
AA seq 433 aa
MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTK
VIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSG
EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR
DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDV
WSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHP
WTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPN
VKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANTGDRGQ
TNNAASASASNST
NT seq 1302 nt   +upstreamnt  +downstreamnt
atgtcagggcggcccagaaccacctcctttgcggagagctgcaagccggtgcagcagcct
tcagcttttggcagcatgaaagttagcagagacaaggatggcagcaaggtgaccacagtg
gtagcaactcctgggcagggtccagacaggccacaagaagtcagctatacagacactaaa
gtgattggaaatggatcatttggtgtggtgtatcaagccaaactttgtgattcaggagaa
ctggtcgccatcaagaaagtattgcaggacaagagatttaagaaccgagagctccagatc
atgagaaagctagatcactgtaacatagtccgattgcgttatttcttctactccagtggt
gagaagaaagatgaggtctatcttaatctggtgctggactatgttccggaaacagtatac
agagttgccagacactatagtcgagccaaacagacgctccctgtgatttatgtcaagtta
tatatgtatcagctgttccgaagtttagcctatatccattcctttggaatctgccatcgg
gatattaaaccacagaacctcttgttggatcctgatacagccgtattaaaactctgtgac
tttggaagtgcaaagcagctggtccgaggagaacccaatgtttcgtatatctgttctcgg
tactatagggcaccagagttgatctttggagccactgattatacctctagtatagatgta
tggtctgctggctgtgtgttggctgagctgctactaggacaaccaatatttccaggggat
agtggtgtggatcaattggtggaaataatcaaggtcctgggaactccaacaagggagcaa
atcagagaaatgaacccaaactacacagaatttaaattccctcaaattaaggcacatccc
tggactaaggattcgtcaggaacaggacatttcacctcaggagtgcgggtcttccgaccc
cgaactccaccagaggcaattgcactgtgtagccgtctgctggagtatacgccaactgcc
cgactaacaccactggaagcttgtgcacattcattttttgatgaattacgggacccaaat
gtcaaactaccaaatgggcgagacacacctgcactcttcaacttcaccactcaagaactg
tcaagtaatccacctctggctaccatccttattcctcctcatgctcggattcaagcagct
gcttcaacccccacaaatgccacagcagcctcagatgctaatactggagaccgtggacag
accaataatgctgcttccgcatcagcttccaactccacctga

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