| Entry |
|
|---|
| Symbol |
PRKN
|
|---|
| Name |
(RefSeq) E3 ubiquitin-protein ligase parkin isoform X3
|
|---|
| KO |
|
|---|
| Organism |
mcf Macaca fascicularis (crab-eating macaque)
|
|---|
| Pathway |
| mcf04141 | Protein processing in endoplasmic reticulum |
| mcf05022 | Pathways of neurodegeneration - multiple diseases |
|
|---|
| Brite |
KEGG Orthology (KO) [BR:mcf00001]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
102134446 (PRKN)
04120 Ubiquitin mediated proteolysis
102134446 (PRKN)
09140 Cellular Processes
09141 Transport and catabolism
04137 Mitophagy - animal
102134446 (PRKN)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
102134446 (PRKN)
05014 Amyotrophic lateral sclerosis
102134446 (PRKN)
05022 Pathways of neurodegeneration - multiple diseases
102134446 (PRKN)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:mcf04131]
102134446 (PRKN)
04121 Ubiquitin system [BR:mcf04121]
102134446 (PRKN)
03029 Mitochondrial biogenesis [BR:mcf03029]
102134446 (PRKN)
Enzymes [BR:mcf01000]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.31 RBR-type E3 ubiquitin transferase
102134446 (PRKN)
Membrane trafficking [BR:mcf04131]
Autophagy
Mitophagy
PINK1-Parkin associated proteins
102134446 (PRKN)
Aggrephagy
Other aggrephagy associated proteins
102134446 (PRKN)
Xenophagy
Other xenophagy associated proteins
102134446 (PRKN)
Ubiquitin system [BR:mcf04121]
Ubiquitin ligases (E3)
Single Ring-finger type E3
RBR proteins
102134446 (PRKN)
Mitochondrial biogenesis [BR:mcf03029]
Mitochondrial quality control factors
Mitophagy factors
Parkin-dependent mechanism factors
102134446 (PRKN)
|
|---|
| SSDB |
|
|---|
| Motif |
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| Position |
4:join(8404640..8404646,8683755..8683918,8864660..8864900,8928265..8928386,9071986..9072069,9150799..9150914,9334385..9334521,9551821..9551882,9570262..9570411,9733884..9733967,9757447..9757564,9766583..9766695)
|
|---|
| AA seq |
465 aa
MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPTDQLRVIFAGKELRNDWTVQNCD
LDQQSIVHIVQRPRRKGQEMNATGGDNARNTAGGCEREPQSLTRVDLSSSVLPGDSVGLA
VILHTDSRNDSPPAGSPADRPIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGP
SCWDDVLIPNRMSGECQSPHCPGTTAEFFFKCGAHPTSDKETSVALHLIATNSRNITCIT
CTDVRSPVLVFQCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKE
LHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPESDQRKVTCEGGNGLGC
GFAFCRECKEAYHEGECSALFEASGTTTQAYRVDERAAEQARWEEASKETIKKTTKPCPR
CHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEWNRVCMGDHWFDV |
|---|
| NT seq |
1398 nt +upstreamnt +downstreamnt
atgatagtgtttgtcaggttcaactccagccatggtttcccagtggaggtcgattctgac
accagcatcttccagctcaaggaggtggttgctaagcgacagggggttccgactgaccag
ttgcgtgtgattttcgcagggaaggagctgaggaatgactggactgtgcagaactgtgac
ctggatcagcagagcatcgttcacattgttcagagaccacggagaaaaggtcaagaaatg
aatgcaactggaggcgacaacgccagaaacacggcgggaggctgtgagcgggagccccag
agcttgactcgggtggacctcagcagctcagtcctcccaggagactctgtgggactggct
gtcattctgcacactgacagcaggaatgactcaccaccagctggcagtccagcagataga
ccaatctacaacagcttttatgtgtattgcaaaggcccctgtcaaagagtgcagccggga
aaactcagggtacagtgcagcacctgcagacaagcaacgctcaccttgacccagggtcca
tcgtgctgggatgatgttttaattccaaaccggatgagcggtgaatgccaatccccacac
tgccctgggactactgcagaatttttctttaaatgtggagcacaccccacctctgacaag
gaaacatcagtagctttgcacctgatcgcaacaaatagtcggaacatcacttgcattacg
tgcaccgacgtcaggagccccgtcctggttttccagtgcaactcccgccacgtgatttgc
ttagactgtttccacttatactgtgtgacaagactcaatgatcggcagtttgttcatgac
cctcaactgggctactccctgccttgtgtggctggctgtcccaactccttgattaaagag
ctccatcacttcaggattctgggagaagagcagtacaaccgataccagcagtatggtgca
gaggagtgtgtcctgcagatggggggcgtgttatgcccccgccctggctgtggagcgggg
ctgctgccggagtctgaccagaggaaagtcacctgtgaaggcggcaacggcctgggctgt
gggtttgccttctgccgggagtgtaaagaagcgtaccatgaaggggagtgcagtgcccta
tttgaagcctcaggaacaactactcaggcctacagagttgatgaaagagccgcagagcag
gctcgttgggaagaagcctccaaagaaaccatcaagaaaaccacgaagccctgtccccgc
tgccatgtaccagtggaaaaaaatggaggctgcatgcacatgaagtgtccgcagccccag
tgcaggctcgagtggtgctggaactgtggctgcgagtggaaccgcgtctgcatgggggac
cactggtttgacgtgtag |
|---|
