KEGG   Macaca fascicularis (crab-eating macaque): 102137660
Entry
102137660         CDS       T02918                                 
Symbol
CBL
Name
(RefSeq) E3 ubiquitin-protein ligase CBL isoform X1
  KO
K04707  E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
mcf04012  ErbB signaling pathway
mcf04120  Ubiquitin mediated proteolysis
mcf04144  Endocytosis
mcf04910  Insulin signaling pathway
mcf05100  Bacterial invasion of epithelial cells
mcf05200  Pathways in cancer
mcf05205  Proteoglycans in cancer
mcf05220  Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:mcf00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    102137660 (CBL)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    102137660 (CBL)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    102137660 (CBL)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    102137660 (CBL)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102137660 (CBL)
   05205 Proteoglycans in cancer
    102137660 (CBL)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    102137660 (CBL)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    102137660 (CBL)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mcf04131]
    102137660 (CBL)
   04121 Ubiquitin system [BR:mcf04121]
    102137660 (CBL)
Enzymes [BR:mcf01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     102137660 (CBL)
Membrane trafficking [BR:mcf04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    102137660 (CBL)
Ubiquitin system [BR:mcf04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   CBL proteins
    102137660 (CBL)
SSDB
Motif
Pfam: Cbl_N Cbl_N3 Cbl_N2 zf-C3HC4 zf-C3HC4_3 Prok-RING_4 zf-RING_2 UBA RING_XB3-XBAT31 zf-C3HC4_2 zf-RING_UBOX zf-RING_5 UBA_RAD5A zf-rbx1 zf-C3HC4_4
Other DBs
NCBI-GeneID: 102137660
NCBI-ProteinID: XP_005579973
Ensembl: ENSMFAG00000040139
LinkDB
Position
14:join(118078484..118078681,118106536..118106783,118145666..118145812,118147814..118147970,118148773..118148894,118149923..118150060,118151953..118152040,118152387..118152518,118152731..118152934,118158975..118159106,118159195..118159572,118161883..118161977,118172246..118172362,118172711..118172808,118173695..118173877,118174844..118175130)
AA seq 907 aa
MAGNVKKSSGAGGGGGSGGSGSGGLIGLMKDAFQPHHHHHHHHLSPHPPGTVDKKMVEKC
WKLMDKVVRLCQNPKLALKNSPPYILDLLPDTYQHLRTILSRYEGKMETLGENEYFRVFM
ENLMKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDTF
RITKADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVF
EFDIFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTR
LGQWAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQD
HIKVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQGCPFC
RCEIKGTEPIVVDPFDPRGSGSLLRQGAEGAPSPNYDDDDDERADDTLFMMKELAGAKVE
RPPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTL
RDLPPPPPPDRPYSVGTESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVP
VSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSSPLVGPEC
DHPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEEDTEYMTPSSRPLRPLDTSQSSRA
CDCDQQIDTCTYEAMYNIQSQAPSVTESSTFGEGSLAAAHANTGPEEPENEDDGYDVPKP
PVPAVLARRTLSDISNASSSFGWLSLDGDPTTNVTEVSQVPERPPKPFPRRINSERKAGS
WQQGSGAAASAATASPQLSSEIENLMSQGYSYQDIQKALVIAQNNIEMAKNILREFVSIS
SPAHVAT
NT seq 2724 nt   +upstreamnt  +downstreamnt
atggccggcaacgtgaagaagagctctggggccgggggcggcggcggctccgggggctcg
ggctcgggtggcctgattgggctcatgaaggacgccttccagccgcaccaccaccaccac
caccaccacctcagcccccacccgccggggaccgtagacaagaagatggtggagaagtgc
tggaagctcatggacaaggtggtgcggttgtgtcagaacccaaagctggcgctaaagaat
agcccaccttatatcttagacctgctgccagatacctaccagcatctccgtactatcttg
tcaagatatgaggggaagatggagacacttggagaaaatgagtattttagggtattcatg
gagaatttgatgaagaaaactaagcaaaccataagcctcttcaaggagggaaaagaaaga
atgtatgaggagaattctcagcctaggcgaaacctaaccaagctgtccctcatcttcagc
cacatgctggcagagctaaaaggaatctttccaagtggactctttcaaggagacacattt
cggattactaaagcagatgctgcagaattttggagaaaagcttttggggaaaagacaata
gtcccttggaagagctttcgacaggctctacatgaagtgcatcccatcagttctgggctg
gaggccatggctctgaaatccactattgatctgacctgcaatgattatatttcagttttt
gaatttgacatctttacccgactctttcagccctggtcctctttgctcaggaattggaac
agccttgctgtaactcatcctggctacatggcttttttgacgtatgacgaagtgaaagct
cggctccagaaattcattcacaaacctggcagttacatcttccggctgagctgtactcgt
ctgggtcagtgggctattgggtatgttactgctgatgggaacattctccagacaatccct
cacaataaacctctcttccaagcactgattgatggcttccgggaaggcttctatttgttt
cctgatggacgaaatcagaatcctgatctgactggcttatgtgaaccaactccccaagac
catatcaaagtgacccaggaacaatatgaattatactgtgagatgggctccacattccag
ctgtgtaaaatatgtgctgaaaatgataaggatgtaaagattgagccctgtggacacctc
atgtgcacatcctgtcttacatcctggcaggaatcagaaggtcagggctgtcctttctgc
cgatgtgaaattaaaggtactgaacccatcgtggtagatccatttgatcctagagggagt
ggcagcctgttgaggcaaggagcagagggagctccctccccaaattatgatgatgatgac
gatgaacgagctgatgatactctcttcatgatgaaggaattggctggtgccaaggtggaa
cggccgccttctccattctccatggccccacaagcttcccttcccccagtgccaccacga
cttgaccttctgccacagcgagtatgtgttccctcaagtgcttctgctcttggaactgct
tctaaggctgcttctggctcccttcataaagacaaaccattgccagtacctcccacactt
cgagatcttccaccaccaccgcctccagaccggccatattctgttggaacagaatcccga
cctcagagacgccccttgccttgtacaccaggcgattgtccatccagagacaaactgcca
cctgtcccctctagccgccttggagactcatggctgccccggccgatccccaaagtacca
gtatctgccccaagttccagtgatccctggacaggaagagaattaaccaaccggcactca
cttccattttcattgccctcacaaatggagcccagaccagatgtgcctaggctcggaagc
acgtttagtctggatacctccatgagtatgaatagcagcccattagtaggtccagagtgt
gaccaccccaaaatcaaaccttcctcatctgccaatgccatttattctctggctgcaaga
cctcttcctgtgccaaaactgccacctggggagcagtgtgagggtgaagaggacacagag
tacatgactccctcctccaggcctctacggcctttggatacatcccagagttcacgagca
tgtgattgcgaccagcagattgatacctgtacgtatgaagcaatgtataatattcagtcc
caggcgccatctgtcaccgagagcagcacctttggtgaagggagtttggctgcagcccat
gccaacactggccctgaggagccagaaaatgaggatgatgggtatgatgtccctaagcca
cctgtgccggccgtgctggcccgccggactctgtcagatatctctaatgccagctcctcc
tttggctggttgtctctggatggtgatcccacaacaaatgtcactgaagtttcccaagtt
cctgagagacctcctaaaccattccctcggagaatcaactctgaacggaaagctggcagc
tggcagcaaggtagtggtgctgccgcctctgctgccaccgcctcgcctcagctctccagt
gagatcgagaacctcatgagtcaggggtactcgtaccaggacatccagaaagctttggtc
attgcccagaacaacatcgagatggccaaaaacatcctccgggaatttgtttccatttcc
tctcctgcccatgtagctacctag

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