KEGG   Macaca fascicularis (crab-eating macaque): 102139399
Entry
102139399         CDS       T02918                                 
Symbol
PDE3B
Name
(RefSeq) cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B isoform X1
  KO
K13296  cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17]
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
mcf00230  Purine metabolism
mcf01100  Metabolic pathways
mcf04022  cGMP-PKG signaling pathway
mcf04024  cAMP signaling pathway
mcf04371  Apelin signaling pathway
mcf04910  Insulin signaling pathway
mcf04914  Progesterone-mediated oocyte maturation
mcf04922  Glucagon signaling pathway
mcf04923  Regulation of lipolysis in adipocytes
mcf04924  Renin secretion
mcf05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:mcf00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    102139399 (PDE3B)
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    102139399 (PDE3B)
   04024 cAMP signaling pathway
    102139399 (PDE3B)
   04022 cGMP-PKG signaling pathway
    102139399 (PDE3B)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    102139399 (PDE3B)
   04922 Glucagon signaling pathway
    102139399 (PDE3B)
   04923 Regulation of lipolysis in adipocytes
    102139399 (PDE3B)
   04914 Progesterone-mediated oocyte maturation
    102139399 (PDE3B)
   04924 Renin secretion
    102139399 (PDE3B)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    102139399 (PDE3B)
Enzymes [BR:mcf01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.17  3',5'-cyclic-nucleotide phosphodiesterase
     102139399 (PDE3B)
SSDB
Motif
Pfam: PDEase_I DUF1129
Other DBs
NCBI-GeneID: 102139399
NCBI-ProteinID: XP_005578607
Ensembl: ENSMFAG00000043764
LinkDB
Position
14:complement(join(50926530..50926744,50928473..50928725,50934818..50934979,50936923..50937126,50946001..50946200,50957762..50957875,50960010..50960121,50961075..50961212,50962002..50962150,50973618..50973691,50974453..50974663,50987081..50987187,51001604..51001740,51004159..51004407,51019630..51019680,51130061..51131038))
AA seq 1117 aa
MRRDERDAKAMRSLQQPDGAGSPPESLRNGYVKSCVSPLRQDPPRGFFFHLCRFCNVELR
PPPASPQQPRRGSPFCRARLSLGALAAFVLALLLGAEPESWAAGAAWLRTLLSVCSHSLS
PLFSIACAFFFLTCFLTRTKRGPGPGRSGGSWWLLALPACCYLGDFLVWQWWSWPWGDGD
AGSPATHTPPEAAAGRLLLVLSCVGLLLTLAHPLRLRHCLLVLLLASFVWWVSFTSLGSL
PSALRPLLSGLVGGAGCLLALALDHFFQIREAPLHPRLSSAAEEKVPVIRPRRRSSCVSL
GETAASYYGSCKIFRRPSLPCISREQMILWDWDLKQWYKPHYQNSGGGNGVDLAVLNEAR
NMVSDLLIDPSLPPQVISSLRSISSLMGAFSGSCRPKINPLTPFPGFYPCSEIEDPAEKG
DRKLNKGLNRNSSPTPQLRRSSGTSGLLPVEQSSRWERNNGKRPHQEFGISSQGCYLNGP
FNSNLLTIPKQRSSSVSLTHHVGLRRAGVLSSLSPVNSPNYGPMAAGSLTNRSPIEFPDT
ADFLNKPSIILQRSLGNAPNTPDFYQHLRNSDSNLCNNCGHQILKYVSTSESDSTDCCSG
KSGEEENIFSKESFKLMETQQEEKTEKKDSRKLFQEGDNWLTEESQNEQQTNIEQEVSLD
LILVEEYDSLIEKMSNWNFPIFELVEKMGEKSGRILSQVMYTLFQDTGLLEIFKIPTQQF
MNYFRALENGYRDIPYHNRIHATDVLHAVWYLTTRPVPGLQQIHNGCGTGNETDSDGRIN
RGRIAYISSKSCSIPDESYGCLSSNIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQ
AVLYNDRSVLENHHAASAWNLYLSRPEYNFLLHLDHVEFKRFRFLVIEAILATDLKKHFD
FLAEFNAKANDVNSNGIEWSNENDRLLVCQVCIKLADINGPAKVRDLHLKWTEGIVNEFY
EQGDEEANLGLPISPFMDRSSPQLAKLQESFITHIVGPLCNSYDAAGLLPGQWIEAEEDN
DTESGDDEDGEELDTDDEEMENNLNPKPPRRKSRRQIFCQLMHHLTENHKIWKEIIEEEE
KCKADGNKLQVENSSLPQADEIQVIEEADEEEERQFE
NT seq 3354 nt   +upstreamnt  +downstreamnt
atgaggagggacgagcgagacgccaaagccatgcggtccctgcagcagccagatggggcc
ggctcgccccccgagagtctgaggaacggctacgtgaagagttgcgtgagccccttgcgg
caggaccctccgcgcggcttcttcttccacctctgccgcttctgcaacgtggagctgcgg
ccgccgccggcctccccccagcagccgcggcgcggctcccccttctgccgggcgcgcctc
tcgctgggcgccctggctgcctttgtcctcgccctgctgctgggcgcggaacccgagagc
tgggctgccggggccgcctggctgcggacgctgctgagcgtgtgttcgcacagcctcagc
cccctctttagcatcgcctgtgccttcttcttcctcacctgcttcctcacccggaccaag
cggggacccggcccgggccggagcggcggctcctggtggctgctggcgctgcccgcctgc
tgttacctgggggacttcttggtgtggcagtggtggtcctggccttggggggatggcgac
gcagggtccccggccacgcacacgcccccggaggcggcggccggcaggttgctgctggtg
ctgagctgcgtggggctgctgctgacgctcgcgcaccctctgcggctccggcactgcctc
ctggtgctgctcctggccagcttcgtctggtgggtctccttcaccagcctcgggtcgctg
ccctccgccctcaggccgctgctctccggcctggtggggggcgctggctgcctgctggcc
ctggcgttggatcacttctttcaaatcagggaagcgcctcttcatcctcggctgtccagt
gccgccgaagaaaaagtgcctgtgatccgaccccggaggaggtccagctgcgtgtcgcta
ggagaaactgcagccagttactacggcagttgcaaaatattcaggagaccttcgttgcct
tgtatttcgagagagcagatgattctttgggattgggatttaaagcaatggtataagcct
cattatcaaaattctggaggcggaaatggagttgatcttgcagtgctaaatgaggctcgc
aatatggtttcagatcttctgattgatccaagccttcctccacaagtcatttcctctcta
cggagtatcagtagcttaatgggtgctttctcaggttcctgtaggccaaagattaatcct
ctcacaccatttcctggattttacccctgctctgaaatagaggacccagctgagaaaggg
gatagaaaacttaacaagggactaaataggaatagttcgccaactccacagctgaggagg
agctcaggaacttcaggattgctacctgttgaacagtcttcaaggtgggaacgtaataat
ggcaaaaggcctcaccaagaatttggcatttcaagtcaaggatgctatctaaatgggcct
tttaattcaaatctactgactatcccgaagcaaaggtcatcttctgtatcactgactcac
catgtaggtctgagaagagctggtgttttatccagtctgagtcctgtgaattctcccaac
tatggaccaatggctgctggctctctaactaatcgatcacccatagaatttcctgatact
gctgattttcttaataagccaagcattattttacagagatctctgggcaatgcacctaat
acaccagatttttatcagcatcttagaaattctgatagcaatctgtgtaacaactgtgga
catcaaatactgaaatatgtttcaacatctgaatcagacagtacagattgctgcagtgga
aaatcaggtgaagaagaaaacattttctcaaaagaatcattcaaacttatggaaactcaa
caagaagagaaaacagagaagaaagacagcagaaaattatttcaggaaggtgataattgg
ctaacagaagagtcacagaatgaacagcaaacaaatattgaacaggaagtatcactggac
ctgattttagtagaagagtatgactcattaatagagaagatgagcaactggaattttcca
atttttgaacttgtagaaaagatgggagagaaatcaggaaggattctcagtcaggttatg
tataccttatttcaagacactggtttattggaaatatttaaaattcccactcaacaattt
atgaactattttcgtgcattagaaaatggctatcgagacattccttatcacaatcgtata
catgccacagatgtcctacatgcagtttggtatctgacaacacggccagttcctggctta
cagcagatccacaatggttgtggaacaggaaatgaaacagattctgatggtagaattaac
cgtgggcgaattgcttatatttcttcgaagagctgctctattccagatgagagttatggc
tgcctgtcttcaaacatccctgcattagaattgatggctctatacgtggcagctgccatg
catgattatgaccacccagggaggacaaatgcatttctagtggctacaaatgcccctcag
gcagttttatacaatgacagatctgttctggaaaatcatcatgctgcgtcagcttggaat
ctgtatctttctcgcccagaatacaacttccttcttcatcttgatcatgtggaattcaag
cgctttcgttttttagtcatcgaagcaatccttgccacagatcttaaaaaacattttgat
tttcttgcagaattcaatgccaaggcaaatgatgtaaatagtaatggcatagaatggagt
aatgaaaatgatcgcctcttggtatgccaggtgtgcatcaaactggcagatataaatggc
ccagcaaaagttcgagacttgcatttgaaatggacagaaggcattgtcaatgaattttat
gagcagggagatgaagaagcaaatcttggtctgcccatcagtccattcatggatcgttct
tctcctcaactagcaaaactccaagaatcttttatcacccacatagtgggtcccctgtgt
aactcctatgatgctgctggtttgctaccaggtcagtggatagaagcagaagaggataat
gatactgaaagtggtgatgatgaagatggtgaagaattagatacagatgatgaagaaatg
gaaaacaatctaaatccaaaaccaccaagaaggaaaagcagacggcaaatattttgtcag
ctaatgcaccacctcaccgaaaaccacaagatatggaaggaaatcatagaggaagaagaa
aaatgtaaagctgatgggaataaactgcaggtggagaactcctccttacctcaagcagat
gagattcaggtcattgaagaagcagatgaagaggaagagcgacagtttgagtaa

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