KEGG   Macaca fascicularis (crab-eating macaque): 102140224
Entry
102140224         CDS       T02918                                 
Symbol
GNAI1
Name
(RefSeq) guanine nucleotide-binding protein G(I) subunit alpha-1 isoform X1
  KO
K04630  guanine nucleotide-binding protein G(i) subunit alpha
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
mcf04015  Rap1 signaling pathway
mcf04022  cGMP-PKG signaling pathway
mcf04024  cAMP signaling pathway
mcf04062  Chemokine signaling pathway
mcf04071  Sphingolipid signaling pathway
mcf04081  Hormone signaling
mcf04082  Neuroactive ligand signaling
mcf04261  Adrenergic signaling in cardiomyocytes
mcf04360  Axon guidance
mcf04371  Apelin signaling pathway
mcf04540  Gap junction
mcf04611  Platelet activation
mcf04670  Leukocyte transendothelial migration
mcf04713  Circadian entrainment
mcf04723  Retrograde endocannabinoid signaling
mcf04724  Glutamatergic synapse
mcf04725  Cholinergic synapse
mcf04726  Serotonergic synapse
mcf04727  GABAergic synapse
mcf04728  Dopaminergic synapse
mcf04730  Long-term depression
mcf04914  Progesterone-mediated oocyte maturation
mcf04915  Estrogen signaling pathway
mcf04916  Melanogenesis
mcf04921  Oxytocin signaling pathway
mcf04923  Regulation of lipolysis in adipocytes
mcf04924  Renin secretion
mcf04926  Relaxin signaling pathway
mcf04928  Parathyroid hormone synthesis, secretion and action
mcf04934  Cushing syndrome
mcf04935  Growth hormone synthesis, secretion and action
mcf04971  Gastric acid secretion
mcf05012  Parkinson disease
mcf05030  Cocaine addiction
mcf05032  Morphine addiction
mcf05034  Alcoholism
mcf05133  Pertussis
mcf05142  Chagas disease
mcf05145  Toxoplasmosis
mcf05163  Human cytomegalovirus infection
mcf05170  Human immunodeficiency virus 1 infection
mcf05200  Pathways in cancer
mcf05207  Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:mcf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    102140224 (GNAI1)
   04371 Apelin signaling pathway
    102140224 (GNAI1)
   04071 Sphingolipid signaling pathway
    102140224 (GNAI1)
   04024 cAMP signaling pathway
    102140224 (GNAI1)
   04022 cGMP-PKG signaling pathway
    102140224 (GNAI1)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    102140224 (GNAI1)
   04081 Hormone signaling
    102140224 (GNAI1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    102140224 (GNAI1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102140224 (GNAI1)
   04670 Leukocyte transendothelial migration
    102140224 (GNAI1)
   04062 Chemokine signaling pathway
    102140224 (GNAI1)
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    102140224 (GNAI1)
   04915 Estrogen signaling pathway
    102140224 (GNAI1)
   04914 Progesterone-mediated oocyte maturation
    102140224 (GNAI1)
   04921 Oxytocin signaling pathway
    102140224 (GNAI1)
   04926 Relaxin signaling pathway
    102140224 (GNAI1)
   04935 Growth hormone synthesis, secretion and action
    102140224 (GNAI1)
   04928 Parathyroid hormone synthesis, secretion and action
    102140224 (GNAI1)
   04916 Melanogenesis
    102140224 (GNAI1)
   04924 Renin secretion
    102140224 (GNAI1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102140224 (GNAI1)
  09154 Digestive system
   04971 Gastric acid secretion
    102140224 (GNAI1)
  09156 Nervous system
   04724 Glutamatergic synapse
    102140224 (GNAI1)
   04727 GABAergic synapse
    102140224 (GNAI1)
   04725 Cholinergic synapse
    102140224 (GNAI1)
   04728 Dopaminergic synapse
    102140224 (GNAI1)
   04726 Serotonergic synapse
    102140224 (GNAI1)
   04730 Long-term depression
    102140224 (GNAI1)
   04723 Retrograde endocannabinoid signaling
    102140224 (GNAI1)
  09158 Development and regeneration
   04360 Axon guidance
    102140224 (GNAI1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    102140224 (GNAI1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102140224 (GNAI1)
   05207 Chemical carcinogenesis - receptor activation
    102140224 (GNAI1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102140224 (GNAI1)
   05163 Human cytomegalovirus infection
    102140224 (GNAI1)
  09171 Infectious disease: bacterial
   05133 Pertussis
    102140224 (GNAI1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    102140224 (GNAI1)
   05142 Chagas disease
    102140224 (GNAI1)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    102140224 (GNAI1)
  09165 Substance dependence
   05030 Cocaine addiction
    102140224 (GNAI1)
   05032 Morphine addiction
    102140224 (GNAI1)
   05034 Alcoholism
    102140224 (GNAI1)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    102140224 (GNAI1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mcf04147]
    102140224 (GNAI1)
   04031 GTP-binding proteins [BR:mcf04031]
    102140224 (GNAI1)
Exosome [BR:mcf04147]
 Exosomal proteins
  Proteins found in most exosomes
   102140224 (GNAI1)
GTP-binding proteins [BR:mcf04031]
 Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 1 (Gi/o) [OT]
    102140224 (GNAI1)
SSDB
Motif
Pfam: G-alpha Arf Gtr1_RagA TniB FtsK_SpoIIIE AAA_29
Other DBs
NCBI-GeneID: 102140224
NCBI-ProteinID: XP_005550437
Ensembl: ENSMFAG00000001117
LinkDB
Position
3:complement(join(141212661..141212851,141217174..141217327,141218988..141219117,141224251..141224379,141228714..141228871,141238868..141239009,141239115..141239157,141292063..141292180))
AA seq 354 aa
MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAG
YSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMT
AELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVK
TTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAA
AYIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
NT seq 1065 nt   +upstreamnt  +downstreamnt
atgggctgcacgctgagcgccgaggacaaggcggcggtggagcggagtaagatgatcgac
cgcaacctccgcgaggacggcgagaaggcggcgcgcgaggtcaagctgctgctgcttggt
gctggtgaatctggtaaaagtacaattgtgaagcagatgaaaattatccatgaagctggt
tattcagaagaggagtgtaaacagtacaaagcagtcgtctacagtaacaccatccagtcg
attattgctatcattagggccatggggaggttgaagatagactttggtgactcagcccgg
gcggatgatgcacgccaactctttgtgctagctggagctgctgaagaaggctttatgact
gcagaacttgctggagttataaagagattgtggaaagatagtggtgtacaagcctgtttc
aacagatcccgagagtaccagcttaatgattctgcagcatactatttgaatgacttggac
agaatagctcagccaaattacatcccgactcaacaagatgttctcagaactagagtgaaa
actacaggaattgttgaaacccattttactttcaaagatcttcattttaaaatgtttgat
gtgggaggtcagagatctgagcggaagaagtggattcattgcttcgaaggagtgacggcg
atcatcttctgtgtagcactgagtgactacgatctggttctagctgaagatgaagaaatg
aatcgaatgcatgaaagcatgaagttgtttgacagcatatgtaacaacaagtggtttaca
gatacatccattatactttttctcaacaagaaggatctctttgaagaaaaaatcaagaag
agccctctcactatatgctatccagaatatgcaggatcaaacacatatgaagaggcagct
gcatatattcaatgtcagtttgaagacctcaataaaagaaaggacacaaaggaaatatac
acccacttcacatgtgccacagatactaagaatgtgcagtttgtttttgatgctgtaaca
gatgtcatcataaaaaataatctaaaagattgtggtctcttctaa

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