KEGG   Macaca fascicularis (crab-eating macaque): 102142443
Entry
102142443         CDS       T02918                                 
Symbol
PRKACA
Name
(RefSeq) cAMP-dependent protein kinase catalytic subunit alpha
  KO
K04345  protein kinase A [EC:2.7.11.11]
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
mcf01522  Endocrine resistance
mcf04010  MAPK signaling pathway
mcf04014  Ras signaling pathway
mcf04020  Calcium signaling pathway
mcf04024  cAMP signaling pathway
mcf04062  Chemokine signaling pathway
mcf04081  Hormone signaling
mcf04082  Neuroactive ligand signaling
mcf04114  Oocyte meiosis
mcf04140  Autophagy - animal
mcf04211  Longevity regulating pathway
mcf04213  Longevity regulating pathway - multiple species
mcf04261  Adrenergic signaling in cardiomyocytes
mcf04270  Vascular smooth muscle contraction
mcf04310  Wnt signaling pathway
mcf04340  Hedgehog signaling pathway
mcf04371  Apelin signaling pathway
mcf04530  Tight junction
mcf04540  Gap junction
mcf04611  Platelet activation
mcf04713  Circadian entrainment
mcf04714  Thermogenesis
mcf04720  Long-term potentiation
mcf04723  Retrograde endocannabinoid signaling
mcf04724  Glutamatergic synapse
mcf04725  Cholinergic synapse
mcf04726  Serotonergic synapse
mcf04727  GABAergic synapse
mcf04728  Dopaminergic synapse
mcf04740  Olfactory transduction
mcf04742  Taste transduction
mcf04750  Inflammatory mediator regulation of TRP channels
mcf04910  Insulin signaling pathway
mcf04911  Insulin secretion
mcf04912  GnRH signaling pathway
mcf04913  Ovarian steroidogenesis
mcf04914  Progesterone-mediated oocyte maturation
mcf04915  Estrogen signaling pathway
mcf04916  Melanogenesis
mcf04918  Thyroid hormone synthesis
mcf04919  Thyroid hormone signaling pathway
mcf04921  Oxytocin signaling pathway
mcf04922  Glucagon signaling pathway
mcf04923  Regulation of lipolysis in adipocytes
mcf04924  Renin secretion
mcf04925  Aldosterone synthesis and secretion
mcf04926  Relaxin signaling pathway
mcf04927  Cortisol synthesis and secretion
mcf04928  Parathyroid hormone synthesis, secretion and action
mcf04934  Cushing syndrome
mcf04935  Growth hormone synthesis, secretion and action
mcf04961  Endocrine and other factor-regulated calcium reabsorption
mcf04962  Vasopressin-regulated water reabsorption
mcf04970  Salivary secretion
mcf04971  Gastric acid secretion
mcf04976  Bile secretion
mcf05012  Parkinson disease
mcf05020  Prion disease
mcf05030  Cocaine addiction
mcf05031  Amphetamine addiction
mcf05032  Morphine addiction
mcf05034  Alcoholism
mcf05146  Amoebiasis
mcf05163  Human cytomegalovirus infection
mcf05165  Human papillomavirus infection
mcf05166  Human T-cell leukemia virus 1 infection
mcf05200  Pathways in cancer
mcf05203  Viral carcinogenesis
mcf05205  Proteoglycans in cancer
mcf05207  Chemical carcinogenesis - receptor activation
mcf05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mcf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    102142443 (PRKACA)
   04310 Wnt signaling pathway
    102142443 (PRKACA)
   04024 cAMP signaling pathway
    102142443 (PRKACA)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    102142443 (PRKACA)
   04081 Hormone signaling
    102142443 (PRKACA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    102142443 (PRKACA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102142443 (PRKACA)
   04062 Chemokine signaling pathway
    102142443 (PRKACA)
  09152 Endocrine system
   04911 Insulin secretion
    102142443 (PRKACA)
   04922 Glucagon signaling pathway
    102142443 (PRKACA)
   04923 Regulation of lipolysis in adipocytes
    102142443 (PRKACA)
   04913 Ovarian steroidogenesis
    102142443 (PRKACA)
   04915 Estrogen signaling pathway
    102142443 (PRKACA)
   04921 Oxytocin signaling pathway
    102142443 (PRKACA)
   04926 Relaxin signaling pathway
    102142443 (PRKACA)
   04935 Growth hormone synthesis, secretion and action
    102142443 (PRKACA)
   04918 Thyroid hormone synthesis
    102142443 (PRKACA)
   04919 Thyroid hormone signaling pathway
    102142443 (PRKACA)
   04928 Parathyroid hormone synthesis, secretion and action
    102142443 (PRKACA)
   04924 Renin secretion
    102142443 (PRKACA)
   04925 Aldosterone synthesis and secretion
    102142443 (PRKACA)
   04927 Cortisol synthesis and secretion
    102142443 (PRKACA)
  09154 Digestive system
   04970 Salivary secretion
    102142443 (PRKACA)
   04971 Gastric acid secretion
    102142443 (PRKACA)
   04976 Bile secretion
    102142443 (PRKACA)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    102142443 (PRKACA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    102142443 (PRKACA)
  09156 Nervous system
   04724 Glutamatergic synapse
    102142443 (PRKACA)
   04727 GABAergic synapse
    102142443 (PRKACA)
   04725 Cholinergic synapse
    102142443 (PRKACA)
   04728 Dopaminergic synapse
    102142443 (PRKACA)
   04726 Serotonergic synapse
    102142443 (PRKACA)
   04720 Long-term potentiation
    102142443 (PRKACA)
   04723 Retrograde endocannabinoid signaling
    102142443 (PRKACA)
  09157 Sensory system
   04740 Olfactory transduction
    102142443 (PRKACA)
   04742 Taste transduction
    102142443 (PRKACA)
   04750 Inflammatory mediator regulation of TRP channels
    102142443 (PRKACA)
  09149 Aging
   04211 Longevity regulating pathway
    102142443 (PRKACA)
   04213 Longevity regulating pathway - multiple species
    102142443 (PRKACA)
  09159 Environmental adaptation
   04713 Circadian entrainment
    102142443 (PRKACA)
   04714 Thermogenesis
    102142443 (PRKACA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102142443 (PRKACA)
   05205 Proteoglycans in cancer
    102142443 (PRKACA)
   05207 Chemical carcinogenesis - receptor activation
    102142443 (PRKACA)
   05203 Viral carcinogenesis
    102142443 (PRKACA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102142443 (PRKACA)
   05163 Human cytomegalovirus infection
    102142443 (PRKACA)
   05165 Human papillomavirus infection
    102142443 (PRKACA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    102142443 (PRKACA)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    102142443 (PRKACA)
   05020 Prion disease
    102142443 (PRKACA)
  09165 Substance dependence
   05030 Cocaine addiction
    102142443 (PRKACA)
   05031 Amphetamine addiction
    102142443 (PRKACA)
   05032 Morphine addiction
    102142443 (PRKACA)
   05034 Alcoholism
    102142443 (PRKACA)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    102142443 (PRKACA)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    102142443 (PRKACA)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    102142443 (PRKACA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mcf01001]
    102142443 (PRKACA)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:mcf03019]
    102142443 (PRKACA)
   03036 Chromosome and associated proteins [BR:mcf03036]
    102142443 (PRKACA)
Enzymes [BR:mcf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     102142443 (PRKACA)
Protein kinases [BR:mcf01001]
 Serine/threonine kinases: AGC group
  PKA family
   102142443 (PRKACA)
Messenger RNA biogenesis [BR:mcf03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     102142443 (PRKACA)
Chromosome and associated proteins [BR:mcf03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    102142443 (PRKACA)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_C
Other DBs
NCBI-GeneID: 102142443
NCBI-ProteinID: XP_005588291
Ensembl: ENSMFAG00000004590
UniProt: A0A2K5UC31
LinkDB
Position
19:complement(join(14512384..14512509,14512897..14513061,14516285..14516407,14516501..14516596,14516686..14516812,14520279..14520361,14522367..14522465,14526290..14526418,14526878..14526939,14538524..14538569))
AA seq 351 aa
MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVML
VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV
MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY
IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT
TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF
NT seq 1056 nt   +upstreamnt  +downstreamnt
atgggcaacgccgccgccgccaagaagggcagcgagcaggagagcgtgaaagaattctta
gccaaagccaaagaagattttcttaaaaaatgggaaagtcccgctcagaacacagcccac
ttggatcagtttgaacgaatcaagaccctcggcacgggctccttcgggcgggtgatgctg
gtgaaacacaaggagaccgggaaccactatgccatgaagatcctcgacaaacagaaggtg
gtgaagctgaaacagatcgaacataccctgaatgaaaagcgcatcctgcaagccgtcaac
tttccgttcctcgtcaaactcgagttctccttcaaggacaactcaaacttatacatggtc
atggaatacgtgcccggtggggagatgttctcacacctacggcggattggaaggttcagc
gagccccatgcccgtttctacgcggcccagatcgtcctgaccttcgagtatctgcactcg
ctggatctcatctacagggacctgaagccggagaatctgctcattgaccagcagggatac
attcaggtgacagacttcggtttcgccaagcgcgtgaagggccgcacttggaccttgtgc
ggcacccctgagtatctggcccctgagattatcctgagcaaaggctacaacaaggctgtg
gactggtgggccctgggggttcttatctatgaaatggctgctggctacccgcccttcttc
gcagaccagcccatccagatctatgagaagatcgtctctgggaaggtgcggttcccttcc
cacttcagctctgacttgaaggacctgctgcggaacctcctgcaggtagatcttaccaag
cgctttgggaacctcaagaatggggtcaatgatatcaagaaccacaagtggtttgccacg
actgactggatcgccatctaccagaggaaggtggaagctcccttcataccaaagtttaaa
ggccctggggatacgagtaactttgacgactatgaggaagaagaaatccgggtctccatc
aatgagaagtgtggcaaggagttttctgagttttag

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