KEGG   Macaca fascicularis (crab-eating macaque): 102147121
Entry
102147121         CDS       T02918                                 
Symbol
PDE4A
Name
(RefSeq) 3',5'-cyclic-AMP phosphodiesterase 4A isoform X1
  KO
K13293  cAMP-specific phosphodiesterase 4 [EC:3.1.4.53]
Organism
mcf  Macaca fascicularis (crab-eating macaque)
Pathway
mcf00230  Purine metabolism
mcf01100  Metabolic pathways
mcf04024  cAMP signaling pathway
mcf04928  Parathyroid hormone synthesis, secretion and action
mcf05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:mcf00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    102147121 (PDE4A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    102147121 (PDE4A)
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    102147121 (PDE4A)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    102147121 (PDE4A)
Enzymes [BR:mcf01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.53  3',5'-cyclic-AMP phosphodiesterase
     102147121 (PDE4A)
SSDB
Motif
Pfam: PDEase_I PDE4_UCR
Other DBs
NCBI-GeneID: 102147121
NCBI-ProteinID: XP_045237009
UniProt: A0A2K5UCF1
LinkDB
Position
19:join(10985795..10986114,11012590..11012781,11015274..11015310,11015526..11015596,11017055..11017104,11017281..11017393,11021254..11021347,11024492..11024715,11026008..11026106,11026203..11026367,11027908..11028007,11028302..11028456,11028660..11028782,11030553..11030735,11033437..11034171)
AA seq 886 aa
MEPPTVPSERSLSLSLPGPREGQATLKPPPQHLWRQPRTPIRIQQRGYSDSAERAEPERP
PHRPIERADAMDTSDRPGLRTTRMSWPSSFHGTGTGSSGAGGGSSRRFEAENGPTPPPGR
SPLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTP
FAQVLASLRSVRSNFSLLTNVPVPTNKRSPLGGPTPVCKATLSEETCQQLARETLEELDW
CLEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEI
PSPTMKEREKQQALRPRPSQPPPPPVPHLQPMSQITGVKKLMHSNSLNNSNIPRFGVKTD
QEELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYML
TLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGV
SNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDM
VLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLE
LYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADL
VHPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEESRGPGHPPPPDKFQFELTLEEEEEEE
ISMAPIPCTAQEALTAQGLSGAEEALDTTVAREASPAQESLDVMAQDESLEAELEEVYLT
QQAQSTGSAPVAQDEFSSQEESVVAVSQSSLSALALQSPLLPAWRTLSVSEHAPGLPGLP
STAAEVEAQREHQAAKRACSACTGTSGEDTSALPAPGGGGSGGDPT
NT seq 2661 nt   +upstreamnt  +downstreamnt
atggagcccccgaccgtcccctcggaaaggagcctgtctctgtcactgcctgggccccgg
gagggccaagccaccctgaagcctccccctcagcacctgtggcggcagcctcggaccccc
atacgtatccagcagcgcggctactccgacagcgcggagcgcgcagagccggagcggccg
cctcaccggcccatagagcgcgccgatgccatggacaccagcgaccggcccggcctgcgc
acgacccgcatgtcctggccctcgtccttccatggcactggcaccggcagcagcggcgcg
ggcggaggcagcagcaggcgcttcgaggcagagaatgggccgacaccacctcctggccgc
agccccctggactcgcaggcgagcccaggactcgtgctacatgccggggcggccaccagc
cagcgccgggagtccttcttgtaccgctcggacagcgactatgacatgtcacccaagacc
atgtcccggaactcatcggtcaccagcgaggcgcacgctgaagacctcatcgtaacaccg
tttgctcaggtgctggccagcctccggagcgtccgtagcaacttctcactcctgaccaat
gtgcccgttcccactaacaagcggtccccgctgggcggccccacccctgtctgcaaggcc
acgctgtcagaagaaacgtgtcagcagttggcccgggagacgctggaagagctggactgg
tgtctggagcagctggagaccatgcaaacttaccgctctgtcagcgagatggcctcgcac
aagttcaagaggatgttgaatcgtgaactcacacacctgtcagaaatgagcaggtcggga
aaccaggtctcagagtacatttccacaacattcctggacaaacagaatgaagtggagatc
ccgtcacccacgatgaaggaacgagaaaaacagcaagcgctgcgaccaagaccgtcccag
ccgcccccgccccctgtaccacacttacagcccatgtcccaaatcacaggggtgaaaaag
ttgatgcatagtaacagcctgaacaactctaacattccccgatttggggtgaagaccgat
caagaagagctcctggcccaagaactggagaacctgaacaagtggggcctgaacatcttt
tgcgtgtcagattacgccggaggccgctcgctcacctgcatcatgtacatgatattccag
gagcgggacctgctgaagaaattccgcatccctgtggacacgatggtgacatacatgctg
acgctggaggatcactaccacgctgacgtagcctaccataacagcctgcacgctgccgac
gtactgcagtccacccacgtactgctggccacgcctgcgctagatgcagtgttcacggac
ctggagattctcgccgccctcttcgcggctgccatacacgatgtagatcaccctggggtc
tccaaccagttcctcatcaacaccaattcggagctggcgctcatgtacaacgatgagtcg
gtgctcgagaatcaccacctggccgtgggcttcaagctgctgcaggaggacaactgcgac
atcttccagaacctcagcaagcgccagcggcagagcctacgcaagatggtcatcgacatg
gtgctggctacggacatgtccaagcacatgaccctcctggctgacctgaagaccatggtg
gagaccaagaaagtgaccagctcgggggtcctgctgctggataactactccgaccgcatc
caggtcctccggaacatggtgcactgcgcagacctcagcaaccccaccaagccactggag
ctgtaccgccagtggacggaccgcatcatggccgagttcttccagcagggtgaccgtgag
cgcgagcgtggcatggaaatcagccccatgtgtgacaagcacactgcctccgtggagaag
tctcaggtgggttttattgactacattgtgcacccattgtgggagacctgggcagacctt
gtccacccagacgcccaggagatcctggacactttggaggacaaccgggactggtactac
agcgccatccggcagagcccgtcgccgccacctgaggaggagtcaagggggccaggtcac
ccacccccacctgataaattccagtttgagctgactctggaggaggaagaagaggaagaa
atatcaatggccccgataccgtgcacagcccaagaggcattgacagcgcagggattgtca
ggagccgaggaagctctggatacaaccgtggcccgggaggcatccccagcgcaggagtca
ttggatgttatggcacaggatgagtccctggaggccgagctggaggaagtgtatttgaca
cagcaggcacagtccacaggcagtgcacctgtggctcaggatgagttctcgtcccaggaa
gaatccgtggttgctgtaagccagagcagcctctccgccctggctcttcaaagccccctt
ctccctgcctggaggaccctgtctgtttcagagcatgccccgggcctcccgggcctcccc
tccacggcggccgaggtggaggcccaacgagagcaccaggctgccaagagggcttgcagt
gcctgcacagggacatctggggaggacacatctgcactcccagctcctggtgggggaggg
tcaggtggagaccctacctga

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