Macaca fascicularis (crab-eating macaque): 7857746
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Entry
7857746 CDS
T02918
Symbol
ND4, KEG98_p04
Name
(RefSeq) NADH dehydrogenase subunit 4
KO
K03881
NADH-ubiquinone oxidoreductase chain 4 [EC:
7.1.1.2
]
Organism
mcf
Macaca fascicularis (crab-eating macaque)
Pathway
mcf00190
Oxidative phosphorylation
mcf01100
Metabolic pathways
mcf04714
Thermogenesis
mcf04723
Retrograde endocannabinoid signaling
mcf05010
Alzheimer disease
mcf05012
Parkinson disease
mcf05014
Amyotrophic lateral sclerosis
mcf05016
Huntington disease
mcf05020
Prion disease
mcf05022
Pathways of neurodegeneration - multiple diseases
mcf05208
Chemical carcinogenesis - reactive oxygen species
mcf05415
Diabetic cardiomyopathy
Module
mcf_M00142
NADH:ubiquinone oxidoreductase, mitochondria
Brite
KEGG Orthology (KO) [BR:
mcf00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
7857746 (ND4)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
7857746 (ND4)
09159 Environmental adaptation
04714 Thermogenesis
7857746 (ND4)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
7857746 (ND4)
09164 Neurodegenerative disease
05010 Alzheimer disease
7857746 (ND4)
05012 Parkinson disease
7857746 (ND4)
05014 Amyotrophic lateral sclerosis
7857746 (ND4)
05016 Huntington disease
7857746 (ND4)
05020 Prion disease
7857746 (ND4)
05022 Pathways of neurodegeneration - multiple diseases
7857746 (ND4)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
7857746 (ND4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03029 Mitochondrial biogenesis [BR:
mcf03029
]
7857746 (ND4)
Enzymes [BR:
mcf01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
7857746 (ND4)
Mitochondrial biogenesis [BR:
mcf03029
]
Mitochondrial DNA transcription, translation, and replication factors
Mitochondrial DNA-encoded proteins
Mitochondrial respiratory chain complex I
7857746 (ND4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Proton_antipo_M
Oxidored_q5_N
Motif
Other DBs
NCBI-GeneID:
7857746
NCBI-ProteinID:
YP_002884235
UniProt:
C3W4Z4
LinkDB
All DBs
Position
MT:10759..12136
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AA seq
459 aa
AA seq
DB search
MLKMIIPTTMLLPMTWLSKNDTIWINLTMHSLAISLIPLLFLNQTNTNLLNHSTYLSSDP
LTTPLLMLTAWLLALMITASQYHLHNESPPRKKFYLSMMVFLQISLIFTFMATELIMFYI
LFETTLIPTLIIITRWGSQAERLNPGMYFLFYTLAGSVPLLIMLIYAYNNLGSLNITLLT
LVAQKLTTTWSHSLTWLTCMMAFMVKMPLYGLHLWLPKAHVEAPIAGSMVLATVLLKLGG
YGMMWLTSILSLTTEYMTYPFLMLSLWGMIMTSSTCLRQTDLKSLIAYSSVSHMALVIVA
SLIQTPWSFSGATVLMIAHGLTSSMYFCLANSNYERTHSRTMLLSRGLQILLPLMAFWWL
AASLTNLALPPTINLLGELFVITTSFSWSHITIVLTGLNMLITALYSLHMFITMQRGTLT
HHMINMKPPFTRENMLMFMHLAPIILLSLNPNIILGFTS
NT seq
1378 nt
NT seq
+upstream
nt +downstream
nt
atgctaaagataatcatcccaacaaccatactactacctataacatggctttctaaaaac
gacacgatttgaatcaacttaactatacacagcttagctatcagcctcattcccttacta
ttcctcaaccaaaccaacactaacctcctcaatcactcaacctatctatcttctgaccca
ctaacaacacccctcctaatattaaccgcctgactcttagctcttataatcacagcaagc
caataccacttacacaatgaatcccctccacgaaaaaagttttacctctctataatggtc
ttcctacaaatctctttaattttcacatttatagctacagaactaatcatattttatatt
ctatttgagaccactctcattcctaccctaattatcatcacccgatgaggcagccaagca
gaacgccttaacccaggcatatacttcctcttctatacactagccggctctgtcccccta
cttattatgctaatctatgcttataataatttaggctctctaaatatcacattactaacg
cttgtagctcaaaaactaacaactacctgatcccatagtcttacctgactaacatgcata
atagccttcatagtaaaaatacccctatatggcttacacttatgacttcccaaagcccat
gttgaagctcccattgctgggtcaatagtcctcgccacagtactcctgaaactaggtggc
tatggcataatatgactcacctctatccttagtctcacaacagaatacataacctacccc
ttcctcatactatctttatgaggcataatcataacaagctcaacctgtcttcgacaaaca
gacctaaaatcacttatcgcatactcttctgtaagccacatagcccttgtaattgtagcc
tctctcatccaaaccccctgaagcttttccggcgcaaccgtccttataatcgcccacggg
ctcacctcttccatgtacttctgcctagccaattcaaactatgagcgcacccatagccgt
accatactactatcccgaggacttcaaattctacttccactaatagccttctgatggctc
gcagcaagccttactaaccttgccctacctcccactattaatctactaggcgaactcttt
gtaatcacaacctcattttcctgatcccatatcaccattgtattaacgggccttaacata
ctgatcacagccctctactctctccacatgttcattacaatacaacgaggaacactcaca
caccacataatcaatataaaaccccccttcacacgagaaaacatattaatattcatacac
ctcgctccaattatccttctatccctcaaccccaacatcatcctgggatttacttcct
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