Methyloceanibacter caenitepidi: GL4_1573
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Entry
GL4_1573 CDS
T03636
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mcg
Methyloceanibacter caenitepidi
Pathway
mcg00300
Lysine biosynthesis
mcg00550
Peptidoglycan biosynthesis
mcg01100
Metabolic pathways
mcg01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mcg00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
GL4_1573
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
GL4_1573
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
GL4_1573
Enzymes [BR:
mcg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
GL4_1573
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BAQ17028
UniProt:
A0A0A8K240
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All DBs
Position
1624587..1626014
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AA seq
475 aa
AA seq
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MGEVISATDGRCEGDPAAPITGFSIDSRAIEPGEGFIAIRGPNRDGHDFVAKALETEAGC
AIVEETFPADTSIEQGGAGAPSEYDEARLVRVRDTFEALNDLGREGRDRTDHAVVIGVTG
SAGKTGTKEALRVALSPSGSVHASAKSFNNHWGVPLTLANMPRGIDYGVFEMGMNHAGEI
SALTRLVRPHIAIVTTVAPVHLGFFASVEEIADAKAEIFEGLVPGGSAVINRDNPHFERL
TAAARSEGAEVVSFGEDERSTVRLMHCDLDPNGSTVTSDILGETITYRVGAPGRHVVQNM
LAVLGAVKLAGADLKAAAEALGALQPPVGRGQRFVIATERDPVCIVDESYNANPASMRAA
LATLGLTPRSEYKRRVVVLGDMLELGKDSPRLHRELAEAVDAAGIDVVFASGADMASLFE
AVPKERRGAYAKTSEELAPALLSTVQPGDIVMVKGSLGSRMAPLVDELKRKFEDR
NT seq
1428 nt
NT seq
+upstream
nt +downstream
nt
ttgggcgaggtcatcagcgccacggacggccgatgcgagggggaccccgccgcgccgatt
accggattttccatcgacagtcgcgccatcgaacctggcgaagggtttatcgcgatccgc
ggaccgaaccgcgatggtcacgacttcgtcgcgaaagccctggagacggaggcaggctgc
gccatcgtggaagagacgtttccggcggacacttcaatcgagcagggcggcgccggtgcg
ccctccgagtacgatgaagcgcgtctggtccgcgttcgggacacgttcgaagcgctcaac
gatctcggccgggagggccgcgaccgcacggaccatgccgtcgtgatcggggtgaccggc
agcgcgggcaagacgggaacgaaggaggcgcttcgggtcgctctcagcccaagcggcagc
gtccacgcctcggcaaagtccttcaacaaccattggggcgtgccgctcaccctcgccaac
atgccgcgcggcatcgactacggcgtattcgagatgggtatgaaccatgcgggcgagatt
tccgcgctcacacgtctcgtgcgtccgcatatcgcgatcgtcacgaccgtggcgccggtc
catctcggcttctttgcgtcggtggaggagatcgccgatgccaaggcggagatcttcgag
gggctggtaccgggcggctccgccgttatcaaccgcgataacccgcacttcgaacgcctg
accgcggccgcgcgcagcgagggtgcggaggtcgtatccttcggcgaggatgagcggtcg
acggtccgtctcatgcactgcgacctcgacccgaacggctcgacggtgacgtcggatatc
ctcggcgaaacgatcacgtaccgtgtaggcgcaccgggacgccacgtggttcagaacatg
cttgcggtcctcggcgcggtgaaactcgccggcgccgatctcaaggcggctgcagaagcg
ctgggtgcgctccaaccgcctgtgggccgcggccaacggtttgtcatcgcgacggaacgg
gacccggtctgcatcgttgatgagtcctataacgccaacccggcctccatgcgcgcggct
ctcgcgacactggggctgacgccccgcagcgaatacaagcggcgtgtggtcgtgcttggc
gatatgctcgaactcggcaaggacagcccaagacttcatcgcgaactcgcggaagccgtt
gacgcggcgggtatagatgttgtctttgcgtccggcgcggacatggcctcgttgttcgaa
gcggtgccaaaggagcggcgtggcgcgtacgcaaaaacgtcggaggaactggcgccggcg
ctgctgtcgactgtgcagcccggcgacattgttatggtcaagggctcgctgggtagccgc
atggcgccgcttgtcgacgagctaaagcgtaagttcgaagaccgttaa
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