Mycobacteroides chelonae: BB28_20550
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Entry
BB28_20550 CDS
T04665
Name
(GenBank) uroporphyrin-III methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mche
Mycobacteroides chelonae
Pathway
mche00860
Porphyrin metabolism
mche01100
Metabolic pathways
mche01110
Biosynthesis of secondary metabolites
mche01120
Microbial metabolism in diverse environments
mche01240
Biosynthesis of cofactors
Module
mche_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mche_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mche00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
BB28_20550
Enzymes [BR:
mche01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
BB28_20550
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
BB28_20550
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
ANA99968
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Position
complement(4095187..4096836)
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AA seq
549 aa
AA seq
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MTRGRKKPGRILFVGSGPGDPGLLTVRARAVLTGATVAFTDPDVPQAVLDLVGSAVELPE
PAPVKPTTGTDDAPTSSDVEAAVEPPLTIDIRPALGDPADVAKTLVAEAKNGVDVVRLVA
GDPLSIDSVLAEVTAVTRTQVAFEILPGLSSSTAVPAYAGLPPGSAHTVADVRGDVDWAA
LAAAPGPLILHATPTHVPDAAKALIEHGLSDQTLVAVTAQGTTCAQRTVETTLASLIDGV
PVDANDPHGPMTGALVLTIGRVVGGRSKLNWWESRALYGWTVLVPRTKDQAGEMSEKLVG
YGALPVEVPTIAVEPPRSPAQMERAVKGLVDGRYQWVVFTSTNAVRAVWEKFAEFGLDAR
AFSGVKIACVGQATADKVRAFGINPELVPEGEQSSLGLLDEFPPYDDVFDPVNRVLLPRA
DIATETLAEGLRERGWEIDDVTAYRTVRAAPPAAQTREMIKTGGFDAVCFTSSSTVRNLV
GIAGKPHARTIVACIGPKTAETAIEFGLRVDVQPETAAVGPLVEALAEHAARLRTEGALP
PPRKKSRRR
NT seq
1650 nt
NT seq
+upstream
nt +downstream
nt
gtgacccgagggcgcaagaagccagggcgcatcctgttcgttggttccgggccgggagat
cctggtctgctgacggtccgcgcacgcgcggtactcacaggtgccaccgtcgcgttcacc
gaccccgatgtgccgcaggcggtactcgatctcgtcgggtccgcggtcgagcttcctgaa
cccgcgccggtcaaacccacgaccggtaccgacgacgcgcccacgtcgagtgacgtcgag
gccgctgtcgagccgccgctgaccatcgacattcgccccgcgctgggtgatcccgccgat
gttgccaagaccctggtcgccgaggccaagaacggtgtggatgtcgtgcggctggtcgcc
ggcgatccgctctcgatcgattcggtgctcgctgaggtcaccgcggtcacccgtactcag
gtcgccttcgagattctgcccgggctgtcgtcgagcaccgcggtgcccgcctacgccggt
ctaccgccgggatccgcacacaccgtcgccgatgtgcgcggtgacgtggactgggcggcg
ctggccgctgctccgggcccgctgatcctgcatgccaccccgacacatgtgcccgacgcc
gccaaggcgctcatcgagcacggtttgtccgatcagaccctggtcgcggtcaccgcgcag
ggcaccacctgcgcacagcgcaccgtggagaccacgctggcctcgctgatcgacggcgtg
ccggtggatgccaatgacccgcacggcccgatgaccggtgccctggtgctgacgatcggc
cgtgtggtcggtggccgctccaagctgaactggtgggagagtcgtgcgctgtacggctgg
accgtgctggtaccgcgcaccaaagatcaggccggcgagatgagcgagaagctcgtcgga
tacggagccctgccggtcgaggtgcccaccatcgccgtggagccgccgcgcagcccagcc
caaatggagagggccgtcaagggtctggtcgatggccggtaccagtgggtggtcttcacc
tccaccaatgcggtgcgtgcggtgtgggagaagttcgccgagttcggtctggacgcccgc
gccttctccggtgtgaagatcgcatgcgtggggcaggcgaccgccgacaaggtgcgcgcc
tttggtatcaaccccgagctggtgcccgaaggagagcagtcctcgctgggcctgctcgat
gagttcccgccctatgacgacgttttcgacccggtgaaccgggtgctgctgcctcgcgcc
gatatcgccaccgaaactctcgccgaggggctgcgggagcgcgggtgggaaatcgacgac
gtgaccgcgtaccgcaccgtgcgtgcggcgccaccggcagcgcagacccgcgagatgatc
aagaccggtggattcgacgccgtgtgcttcacctcgagctcgacggtgcgcaatctggtg
ggtatcgccgggaagccgcatgcgcgcaccatcgtggcctgcatcggaccgaaaaccgcg
gagaccgcaatcgaattcgggctgcgggtggacgtgcagccggagaccgccgccgtcggc
ccgctggtcgaggccctcgccgagcatgccgcgcggttgcgcaccgagggcgcgctgccg
ccgccgcgtaagaagagccgtcggcgctag
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