Micromonospora chalcea: PVK74_00755
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Entry
PVK74_00755 CDS
T08919
Name
(GenBank) thiamine pyrophosphate-dependent enzyme
KO
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
Organism
mchl
Micromonospora chalcea
Pathway
mchl00280
Valine, leucine and isoleucine degradation
mchl00640
Propanoate metabolism
mchl00785
Lipoic acid metabolism
mchl01100
Metabolic pathways
mchl01110
Biosynthesis of secondary metabolites
mchl01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
mchl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
PVK74_00755
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
PVK74_00755
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
PVK74_00755
Enzymes [BR:
mchl01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
PVK74_00755
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Motif
Pfam:
E1_dh
Transketolase_C
Transket_pyr
PFOR_II
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
WDQ03315
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All DBs
Position
complement(171558..173663)
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AA seq
701 aa
AA seq
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MDAGLLLDYFDAQIQSRHLDLALRWLQSKREGFYTIGSSGHESNAAVALALRPTDPALLH
YRSGGFYAARAGQVPGSTPITDVLHSAAASRRDPISGGRHKVFGHRALNVIPQTSTIASH
LPRAMGMAFALERGVGDTGYPADAVVVCSFGDASANHSTAAGALNAVGWAAHQGLGMPVL
FVCEDNGIGISTRSPHGWVDRMLSALPALDYTAVDGADPARLLAVAGEVADRVRAGRRPA
VLHLRTVRFMGHAGSDAELAYRSRSEILADYARDPLLATAAVLARRGILAPAESLARYEQ
TRKLVMDQAEAMLGRVERLPDAAAVTAPLTERRTDRVSAAAGRAGAGREKVFGGRLPESR
GPLTLAQSVNAALHDALLTWPQAQVFGEDVARKGGVYGATRGLRKAFGANRVFDTLLDEQ
TILGVALGGALAGTLPIPEIQYLAYLHNAEDQLRGEAASLRFFSDGQYGNGMVVRIAGLA
YQKGFGGHFHNDNSVAVLRDIPGLALAVASHPATAPALLRQCLALAEQEKRVCVFLEPIA
LYHTRDLHSDGDGGWLARYAPPDEWAATETPLGQVRTVRDGDDLALVTFGNGVPMSLRVA
ETLAAERGAGTRVVDLQWLAPLPAASMLAALDGVPRVLVVDETRAGGGVSEAVVAALVDA
GYPGRISRVNSVDSYVPLGPAADHVLLGEHDVLTAARALLD
NT seq
2106 nt
NT seq
+upstream
nt +downstream
nt
atcgacgccggcctgctgctcgactacttcgacgcccagatccagagccgccacctcgac
ctcgcgttgcgctggctgcagtcgaaacgggagggcttctacacgatcggatccagcggc
cacgagagcaacgccgccgtcgcgctggcgctgcgcccgaccgatccggcgctgctgcac
taccggtccggcggcttctacgccgcccgggccgggcaggtccccggctccaccccgatc
accgacgtgctgcactccgccgccgcgtcccggcgggacccgatctccggcggccggcac
aaggtgttcgggcaccgggcgctgaacgtcatcccgcagacctcgacgatcgcctcgcac
ctgccccgcgcgatgggcatggcgttcgcgctggagcggggcgtcggcgacaccggttac
ccggccgacgcggtggtggtgtgcagcttcggcgacgcctcggccaaccactccaccgcg
gcgggcgcgctgaacgccgtcgggtgggccgcccaccaggggctcgggatgccggtgctg
ttcgtctgcgaggacaacggcatcggcatcagcacccggtccccgcacggctgggtggac
cggatgctgtccgcgctaccagccctggactacaccgccgtcgacggcgccgatcccgcg
cggctgctcgccgtcgcgggcgaggtggccgatcgggtacgcgccggacgccgccctgcc
gtgctgcacctgcgcacggtccggttcatgggccacgccggttccgacgccgagctggcg
taccggtcccggtcggagatcctcgccgactacgcccgcgacccgctgctggccacggcg
gcggtgctggcccggcgcggcatcctcgccccggccgagagtctggcccgctacgagcag
acccgcaagctggtcatggaccaggccgaggcgatgctcgggcgggtcgagcggctgccc
gacgcggctgcggtgaccgctccgctgaccgaacgccggaccgaccgggtcagcgcggcc
gccggacgggccggcgccggacgggagaaggtgttcggcggccggctccccgagtcgcgc
ggaccgctcacgctcgcccagtcggtcaacgccgcgctgcacgacgcgctgctcacctgg
ccgcaggcgcaggtcttcggcgaggacgtggcgcgcaagggcggcgtctacggcgccacc
cgcgggctgcgcaaggcattcggcgcgaaccgcgtgttcgacacgctgctggacgagcag
accatcctcggggtggcgctcggcggcgcgctggccggcacgctgccgatcccggagatc
cagtacctcgcctacctgcacaacgccgaggaccagctgcgcggcgaggccgcctcgctg
cggttcttctccgacgggcagtacggcaacggcatggtggtccggatcgccgggctggcg
taccagaaggggttcggcgggcacttccacaacgacaactcggtggcggtgctgcgggac
atccccggcctggcgctggctgtcgcctcccacccggccaccgcgccggcgctgctgcgg
cagtgcctcgcgctggccgagcaggagaagcgggtctgcgtgttcctggagccgatcgcg
ctctaccacacccgtgacctgcacagcgacggcgacggcggctggctggcccggtacgcc
ccgccggacgagtgggcggccaccgagacgccgctcggacaggtccggaccgtacgcgac
ggcgacgacctggcgctcgtcacgttcggcaacggcgtgccgatgagcctgcgggtggcc
gagacgctggccgccgagcggggtgccggcacccgcgtcgtggacctgcagtggctcgcg
ccgctgccggccgcgagcatgctcgccgcgctcgacggcgtaccccgggtgctggtggtg
gacgagacccgggccggcggcggcgtctccgaggcggtggtggccgccctggtcgacgcc
ggttacccggggcggatctcccgcgtcaacagcgtcgacagctacgtcccgctgggcccg
gcggccgaccacgtcctgctcggtgagcacgacgtgctgactgcggcccgcgcgctgctc
gactga
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