Melitaea cinxia (Glanville fritillary): 123666011 Help Entry 123666011         CDS       T09237                                  Name (RefSeq) E3 ubiquitin-protein ligase UBR4   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism mcix  Melitaea cinxia (Glanville fritillary) Brite KEGG Orthology (KO) [BR:mcix00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:mcix04121]     123666011 Enzymes [BR:mcix01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      123666011 Ubiquitin system [BR:mcix04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     123666011 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  E3_UbLigase_R4 E3_UBR4_N UBR4 zf-UBR Flu_PB2_1st Motif Other DBs NCBI-GeneID:  123666011 NCBI-ProteinID:  XP_045456184 LinkDB All DBs Position 2:16603901..16668419 Genome browser AA seq 5235 aa AA seqDB search MAASGGNIEWSTAVKPILTALYGPFFDKNDAVEIIQAIIKSENEFENHEDIYDLFYTCFA CLSAHFISINANNLPPDQLSTAHDAFRIMLRHILKKISQAVLTYDDSINMAAPKVTFKQL LLPILGLCGIDGGGLPQSELAILTSLLKSSKLPANVNVTETQTTKSSVSPITSLASQSTT QEKQPPSNAQRRSDALLEQLTMPLKNPMASLIQNQPAAVVLSPGSKDSLESTKDVNVSQQ ITTDVKKWMHSTCASLLMELRAGPMLLNVCSSLPCLYRYLTRWRDAKESAIPPQFNSEVK LLNFLMNEAYVCRMALSLPCLEPLTPERIALLSDLATTWLICAVTAQATLHPRDDENEEM TATLVERALGLYNTIGETFKQSTRAGGYVYQNHLMIGAWVLLCGLHHALGGAPPSSAPKS PAKTPSRPYNLTKMQQSLSAVWVALGDRCLAWTGTLLSDARLEALSATPGTADAPAPLHI LAHHTAHQRELRLAAAAPLHQLLVSLAVVCYRKATNLKRAVVQKQNQDADPDRSDSTVYF QDMILCSEDSETDDEDSEPLFGLWFESTLVAPDALDSGLTRAAPDSDDAPDDAPAQQALL LDKAEPYSYITLATDIFNLLTEEIIGEGVERLGTTAQQLHEAHHALLVALAKDLDRETAR TDTGTISPCFGARLGALYAAFSSALVRYLHNLQPQLQQQLISTGSDRSNVTPLQVGPRVA KLLGGMVLSKTAAERENNILVMWHKIINTLQECALQNQPSQDHDYEDLNVEHAQLLVYLF HSLTLMQKKSVLLMTSNAIIKVVETLGISDRKRAMNLAPHQLILTTRLMLLLEYLMKHLY DAPQFLLQQIEWNLVIAPGLAQRPSSDGNNTSVNTTTDNGQIKSRIYCELMFIELAYITP TQDDSSMRPRFYALTNAEINNQENPKLDGLACNFVLGTPHKLKYPLLLDALLSLLNSACL CDNPQYHNSPAALAAAHYCFQTAWRLVISMPPATPHMDKLQAGTAAELPSPLPLHALVWA PRADNKKVFNPWLKDALVKQGMYTQYAENLLAGVSASCDNIKYTAWLASETMKHLKQNLT ADGLPSLLDVISCDAALMRLKVCLVDSASASEAHQFMPDLLDLLETILECCRLSVGIEIS RAADASPGGPAEAEAAVARARLQVCGGEGAAGAAGAAALGSWLKAQLPPHVAAALEACAA PPARAVDTTAYESHIIPSESAVLALVSSHSELMIVRGKYSIGASLTMLAYSAAKLLEIGS SKLAENTNLTKKTLDLIVPALTDGRLQFLTEPLAATLNALVPQVNKAEQLIHEHILKTTY TVLVDHLQPSTEKTLRHMIIYWEKILDRPAGRVAYENVFADNSGYALGKILLAAPNGKSA FTDKVIKLFIKIFTGCENSELNALCVSVSKFIGVADQQKLVNLLSHICSVASATPTNGNV GTANATPTETELPTPTSGAADASPASVALRNALRSVFRTEDANGANAANVANAANRNLTD QDLPVFDAPIPAPRPPVEPAQQSKNGSWSEGGSKDNTSAVVVSTEAGNPFSAHDNATLLS LLCKHIVHHGGEKVCERMVSALIDVSGASCTPLLLRELCRLADAHSGAEHRQLFPAALSW LSTCVDNLSSPEVLEKLEEGQLDTNITSQIESACVLLSYLGDALHAIGSAQPHTWRSVSP TWESPSDLGFDFDYADEQQDEDDTSADDSDEDAMLQYKLCTFTVTQREFMNQHWYHCHTC KMVDGVGVCTVCARVCHRGHDVSYAKFGNFFCDCGAKPDSSCQALVKRSVTLGGARGGSG GTEETPPAPSIRRRPSSPTPPALLAPPRRPVLAHNIQGCRPFLLSFGGWAGCLERVRRLL GALAGPVRAACERGAAVGAHGRAQRALAQLHLGEKRFTHTDTLMLPTLGSQEGAFENVRM SYTGENGQTIRQLMSAHKLRRVAMCCLASPHGRRQHLAVSHEKGKITVLQLSALLKQADS SKHKLTLTRLSSAPIPFTVLSLGGNPWNEDLLAVCGLKECHVLTFNSGGAVADHLVLNTG LEANNYVIKAIWLPGSQTQLALVTSDFVKIFDLSKDLNNPMHHFLVPSGKVRDVTFVNQE DIMHMLCMSSAGHIYWQPMSEESRATLGTFYVTNTLEVLHPEIQDVAGLVGGGGVSIYYS HILKMLFFSYAQGKSFLAPLNTVEDSVKGTAMITLSSSSAQKEGGRGKQGGVQSLCQWAE VPGHPGLVTAVMQASNNPVVLMLTPNNIYVQEIKVVPAKAKITDMVAVRHWCGGGGEQKS TLILLCEDGSLRMYAASNEDTGYWLSPAIQPVHAPRRRPRLLTHHNKGKAQQVVTKSNSN GTPQFPIDFFEHCVAMSDIEFGGNDLLQVYNTAQIKHRLNNTGLYVVSTKMSGFTMEVVN SDPNMVMCGIRVLLGNQDVARTPAYVEIHGRSIQTIVVRNRWFDIPLTREESLQSDKKLV INFGPSQDPDGVTVVDSVKVYGKNKEQFGWPEENEDPSACPSSSKVAQESESSSGSWKPS SLERLACAALEALELGAGAPASSGAAAGAEAGAEAARKLLCAPASAHLHARAQCLLRAVH QAQYHQFKDQAILKYVSTSLRELRDTADARNIDPEAYFRLVLLARGVAVARPQHLVKYSG PTPPKPTDGDWSALWKADCQDEPDHEPHLCALLSSVLWKLTGCRSQTTGPPGILSYGLRH AEHTLHALADTIHAFQLHGDSDCIDFGNQIYLSLLLAEDQSISFGAKAALMRVLRPRVKR RRVYIPSPPNTPGAVSSVTTAQPAGSITEAVVSEAELSANRDDQQENQYMDVDDSLEPMV LLAPDGGLEALLDIPTDADDETMVELAIALSLQEQGRRAPPAPAPPPAPAPHAPAYSDAT ASPNGSDDEGSTAATDGSTLRTSPAEAGGSAASDSGGSAAESIGGVSGRSSAYGEMSAPS GQPCSTVVEVPAAVAAGPSSSSQPMPSTSRAAEVENEARKLHALRLSLLSAALDALPTLR TLPGVRAIPFVQVVLMLAGDLDSSVEGDRAVLERLLEVLVGELDIQPEEPSSGEDRTEKR ELQLAIMRLELLVSELDEQVAVHSPPVHERTNRRELQLVIMRLLSVLMARWKTCGAHAGG AGGGAARGEAPGAACAAHVSRLAAAALVRAGAPKHCYNVLAALLPYWKEKTANSGTTTTV QQLLKPQPPQPLPDMQPFFVKEYVKSHALDVFDNYPQLVMEMALRLPCQIHKHCDPKHFD ARWRTLLCEYMMNQQTPLRKQVRKLLLLLCGTRELYRQLRDVHALDTHLNAARALLATDP AYDKLVRLMDHLKACAEIVSARTGNWQHTCATERRETLGWLVGAARRLHPHVAPTVLQLL QAALCAPAPPAPPTPHTPPGTNWPDRERSTESDAFVSDGSKFQEHRVPQLVQQILKQVNQ DELKLFVKAFLLETNSTAVRWQAHALLLAIYNNCSQTEQASLVSLLWSLWPTLPQYGRKA VQFVDLLGYFTLKTPNIDTESYIGSAVELLRNQNQLLSSHGNSALYASLGAYVELDGYYL ESEPCLVCNNPEVPMASIKLPTIKIDSKFTTTTQIVKLVNSHMISRISLRIGDIKRSKMV RVINFYYNNRTVQAVQELKNKPSMWHKAKRVQLQSGQSEVRVDFPLPIVACNLMMEYADF YENQQATGESLQCPRCSQSVPANPGVCGNCGENVFQCHKCRAINYDEKDPFLCHACGFCK YAKFDYTLTARPCCAVDTIENDEERKKMVQTIGALLDKADRVYRQLIANKPVLESLVHKI SEHRVEGRADENSNGAGGAFGGAQINRVIQMLAHKYCVESKGHFEDLSKIIQKVLACRKE LVAYDRSQSEQLEGDTLPVYAGLLQNYDGDVTKESGGSCYGCSLACAEQCLTLLRALASQ REHRARLCRFGLVHELVHHNLHRGTPQCQDEVRSLICLVTRDNLPATKQLCYLLSQRITL SLMGHAASQDHNNSVRPLVLLLGALVKVQDSVECWEVRLRCVVKLWVWCCPQLTEVVGIP PAATAILKSEALSGIPGINTSSPNSHQFALQQVALPCLRYMQELMEPAAPAAAPAPAADD QAKDTKESTQPTAPPPIVLQANTGNLVVDLSAWLAGRVPHKQWRKLVAKNEIPPADTTLP TRDIHLAHKYLGKWKEKMLLSHGMRTLSLDAGGWLRPVMFDPSSRIARDTACQMVKSLCD SYDRTKAVLILLTSFLPEVGAAGEASEQFLQLYQSLASEAPWKQFLALRGVLQQIADLMT KEIDQLHRLEETTLTSDLAQGYALKRLTELLAMFLEEAGARRAYKTRLVGAVLGGYLALR RLVVQRTRLTDDTQEKLLELLEEMTTGTEAETAEFMAVCIETVQKYPLHDYRTPVFIFER LCSIIYPEENDVGEFFLTLEKDPQQEDFLQGRMLGNPYSSLEPGMGPLMRDVKNKICTDC ELVALLEDDNGMELLVCNKIMSLDLPVKEVYKKVWCTSGEGVDAMRVVYRMRGLLGDATE EFVETLSQTNAETVDDEQVYRMANVLADCGGLEVMLQRLAAIGRVACARSLAGTLLRLLA LCARVRRCVRVLTRPEARALPVLLHALSLAAADERDGPRAPLVYQLLEIMERILSVAASE SLESFLQFSLTFGGPEHVQALLNCTECPGIRNNSVALGHLTRVLAALVYGNDLKMAMLVD HFKPVLDFNRLDNEQWSDEEFRMELFCVLCANIERNSIGGTLKDYLISLGVVRDALEYIM KHAPCVKPTLVCTDSDELKEFISRPALKYILRFLTGLAADHEPTQMLVCENVIPIVHRLE QVSSGEHVGSLAENLLEALRSQPQCAAKVQQVRDFTRQEKKRLAMAVRERQLGALGMRSN ERGQVTAQCSLTQQVADLAEEAGAVCCICREGYKYQPTKVLGIYTFTKRCPVEEYEARAR KTLGYTTVSHYNIVHVECHMAAVRLARARDEWESAALQNASTRCNGLLPLWGPYVPESAF ASCLARHTTYLQECTGHRDIGHSCTVHDLKLLLLRFARGLSFHNDTGGGGPLSNMQLVPA LMHMALYVINTTRVAAREVSALEASLAWPPPRVLESAHDAEGPLYYLTLMLLLYPHAKWR ALRLDMMKRMLLVGHVRDVARGGPALRALAPEHRAPRAWPEYKPYLVFVALIHQLYTVMF KNVNATTVEQWPIKLAEYIRHNDEANAKAAERIVTTLTDELLPCDSLAELCDAAGFLDDA PEPDALLQRLLDEQP NT seq 15708 nt NT seq  +upstreamnt  +downstreamnt atggccgcatcgggaggaaatatagaatggtctaccgcagttaaaccaatattaacagca ctttacggcccattttttgataaaaatgatgccgttgaaattatacaagctataatcaaa agtgaaaacgaatttgaaaatcatgaagacatctacgaccttttctacacctgctttgcg tgtctttcggcacattttattagcatcaacgcaaataacttgccaccagatcagctcagc actgctcatgacgcctttagaattatgctacgacacattctcaaaaagatttctcaagcc gtgttgacctatgatgattccataaatatggctgcaccaaaagtgactttcaaacagctt cttctaccaatccttggcctatgtggtattgatggtggtggtctgccacagtcagagctt gctattttgacttcccttctcaagtcatccaagcttccagcaaatgttaatgtaactgaa actcaaactacaaagtcttcagtaagccctatcacatcccttgcatctcaatcaacgaca caagaaaagcaaccaccgtcaaatgctcaacgtaggtccgacgcattgttggagcagctg acaatgccgttaaaaaatcctatggcttcattaattcagaatcagccagcagcagtcgta ttatcccccggaagcaaagatagtttggaaagtacaaaagatgtaaatgtttctcaacag attactacagatgtaaagaaatggatgcattcaacttgcgcatcattgctaatggaactt cgagcgggacccatgttgctgaacgtgtgctcgtctttaccgtgtctgtaccgctatctg actcgatggcgtgacgctaaagagagcgctatacccccgcagtttaattccgaagttaaa ctcctcaatttcctcatgaatgaagcgtatgtgtgccgcatggcgctgtcactaccgtgc ctagagcccttgacaccagaacgcatcgctctactgagtgacctagcaaccacttggctg atttgcgccgttacggcacaggcaacgctacatccaagagacgatgaaaatgaggaaatg actgcaaccctagttgagagagcacttggtctttacaacactattggggaaactttcaaa cagtccactcgggctggtggatatgtatatcaaaaccacctgatgatcggcgcttgggtt ctactgtgtggtcttcatcatgctttgggaggagcacccccctcttccgcccctaagagc cccgctaaaacaccttcgcggccttacaacctcactaaaatgcaacaaagcctaagtgcg gtgtgggtggcgctgggtgatcgctgcctagcgtggactggcacgctgctgtcggatgcg cggctggaggcgctgagcgcgacgccgggcactgcggacgcgcccgcgccgctgcacatc ctggcgcaccacaccgcgcaccagcgcgagctgcgcctcgccgccgccgcgccgctgcac cagttgctagtatcgttggctgtggtgtgttaccgaaaagccacaaatttaaagagggcc gtcgtacaaaagcagaaccaagacgccgaccccgatagatccgactcaaccgtttacttc caggatatgatactctgctctgaggattctgaaactgatgatgaagatagcgagccgctg tttgggctgtggttcgagtcgacgctggtggcgcctgacgcgctcgatagcggactgacg cgcgccgcgcccgacagcgacgatgcgcccgacgacgctcccgcgcaacaggcattgctg ctcgacaaggccgagccatactcgtacataacactagcaacagatatattcaacctgtta accgaagagataatcggcgaaggagtagaacgcttgggtactacagctcagcagttacac gaagcacaccatgctttactcgttgcgcttgctaaggacctcgatagagagactgctagg actgatactggaactatatccccatgtttcggtgcgcgtctcggagcgctgtacgccgcg ttcagttcggcgctcgtgcgctacctgcacaacctacaaccgcaattgcagcaacaactc atctcgactggctccgacaggagcaacgtgacgccactgcaggtcggtcctcgagtagca aagctgcttggtggtatggtcttgagtaagacagcagctgaacgtgagaacaacatcctt gttatgtggcataagattatcaacactctacaagagtgtgccttgcagaatcaacccagc caagatcacgattatgaagacttgaacgttgagcatgcccagctgcttgtatatttgttc cattctttgactctaatgcaaaagaaatctgttcttcttatgacatccaatgcaatcatt aaagttgtcgaaaccctcggtataagtgatagaaaacgtgcgatgaatttagcacctcac cagctaattttgactacaagacttatgcttctgttggaatatctcatgaaacatttatat gacgctccgcagttcttgctgcaacagattgaatggaatctcgtcatagcaccggggtta gcacagcgtccctcctcagatggcaacaacactagcgtaaatacaacgacggataatggg caaataaaatctcgtatatactgtgaattaatgtttatagaactcgcttatattacaccg actcaagatgactcatctatgagacctaggttctacgcgcttactaacgcagaaattaac aaccaggaaaatccgaaattagacggcttagcatgcaatttcgtgctgggaacaccacac aagttgaaatatcccttacttctggacgcattgctatctctactgaactccgcgtgcctc tgcgataaccctcagtatcacaactcgccggctgctcttgccgccgcgcattattgcttc cagactgcttggaggctggtgataagcatgccgcccgcgaccccgcacatggacaagctg caggcgggcaccgcggccgagttgccgtcgccgctgccgctgcacgcgctggtgtgggcg ccgcgcgccgacaacaagaaggttttcaacccctggctcaaggacgcactcgtcaagcag ggcatgtacacgcagtacgcggaaaacttattagctggtgtaagtgcttcatgtgacaac atcaagtacacagcctggcttgcttctgaaactatgaaacatctgaaacaaaatctcaca gctgatggccttccatcccttctcgatgtgatatcatgcgacgctgctttgatgagactt aaagtttgtctcgtggactctgcttcagcatctgaagcgcatcaattcatgcccgattta ttggatctacttgaaacaattctcgagtgctgccgactaagcgtggggatagagatatcg cgggcggcggacgcgagcccgggcggcccggcggaggcggaggcggccgtggcgcgcgcg cggctgcaggtgtgcggcggcgagggcgcggcgggcgcggcgggcgcggcggcgctgggc tcgtggctcaaggcgcagctgccgccgcacgtggccgccgcgctcgaggcctgcgccgcg ccgcccgcgcgcgccgtcgacacgactgcttacgaatcccacatcataccgtctgaaagt gcagtcttggcactcgtgtcgtctcacagtgaacttatgattgttcgcggcaagtactcc atcggagcgtccttgactatgctcgcctactccgcggcgaagcttctagaaatcggctct agcaaactagctgagaataccaatctcactaagaagactttggacttgatcgttccagct ttgactgatggcagactccagttcttaacggaaccattggcagctactttgaatgcttta gtaccacaagtaaacaaagcagaacagctcatacatgaacatatattaaagacgacatat acggttttggttgatcatctgcaaccatcaacagagaaaactctgcggcatatgattatt tactgggagaagattctagatcgaccagctggaagagtagcatacgaaaatgttttcgcg gacaactctggttacgccctcggaaaaatattactcgcggcaccaaatggaaaaagtgcc ttcactgataaagttataaagctcttcatcaagatatttactggttgcgaaaattcggaa ctgaacgctctttgtgtatcagtgagcaaatttattggggtggcagatcaacaaaaactt gtcaatctgctttctcacatctgttcagttgcatcagcgacgccaacgaacggcaacgtg ggcacggcgaacgcgacgccaaccgaaacggagttgccgacgccgacatcgggcgcggcg gacgccagcccggcctccgtggccctccgcaacgcgctgcgctccgttttccgcaccgag gacgccaacggagccaacgcggccaacgtcgccaatgccgccaaccgcaacctgaccgat caggacctgcctgtcttcgacgcgccaattccagctccaagacctccagtagagcctgca caacaatccaaaaatggcagctggtccgaaggcggtagcaaagataatacaagcgcagtt gtcgttagcactgaagctggcaacccattctcagcccatgataacgctacacttttatct ctgctttgtaagcacattgtccatcacggcggggagaaggtgtgcgagcgcatggtgagc gcgctaatagacgtgagcggcgcgtcgtgcactccgctgctgctgcgcgagctgtgtcgc ctggcggacgcgcacagcggcgccgagcaccgccagctgttccccgccgcgctctcctgg ctctccacctgtgtggacaaccttagcagtccagaagtacttgaaaagttggaagaaggc caattagacacgaacattacctcgcagatcgaatcagcatgcgttctcttatcttatctc ggtgatgcgttgcatgctatcggatctgcgcagccacacacttggcgatctgtcagtccc acatgggaatctccatcagatctcggtttcgacttcgattatgctgatgaacaacaggat gaagacgatacgagtgctgacgactctgacgaggacgccatgctgcagtacaagctgtgt acgttcacggtgacgcagcgcgagttcatgaaccagcactggtaccactgccacacgtgc aagatggtggacggcgtgggcgtgtgcacggtgtgcgcgcgcgtgtgccaccgcggacac gacgtgtcctacgccaagttcggaaatttcttctgtgactgcggcgccaagcccgactcg agctgccaagctttagtaaaacgttcggtgacactgggaggcgctcgcggaggtagcggt ggcacggaggaaactccaccggcgccctctattagacgccgtccatccagtcctactccc cctgcgctacttgcgccgccacgacgccccgtgctcgctcataacattcaaggctgccgg ccgttcctgctgtcgttcggcggctgggcgggctgcctggagcgcgtgcggcggctgctg ggcgcgctggcgggcccggtgcgcgcggcgtgcgagcgcggcgcggcggtgggcgcgcac ggccgcgcgcagcgcgcgctcgcgcagctgcacctcggcgagaagcgcttcacgcacacc gacacgctcatgctgcccacgctgggatcgcaagaaggcgcgtttgaaaatgtacgcatg tcatacacgggtgagaacggacaaacaatccggcaactgatgtcggctcataaactgcgt cgtgtcgccatgtgttgtcttgcttcaccccacggccgacgacagcacctggctgtgtca cacgaaaaaggaaaaattacagttctccaactatcagctttactcaaacaggctgattct tctaaacacaaattgacgctaactcgactatcttccgctcctataccattcactgtgctc agtctcggcggaaacccatggaatgaggatcttttagccgtgtgtggattgaaagaatgt cacgtccttacatttaatagtggaggtgcggtagcagaccacttagttctgaacacaggt ctggaggccaacaactatgtaatcaaagcaatctggttaccgggctcacagacgcagtta gctctcgtcacttcagactttgtcaagatattcgaccttagcaaggatttgaataatcct atgcatcacttccttgtaccgagtggcaaggtccgcgatgttacattcgtgaatcaagaa gatattatgcacatgttatgcatgagctccgcgggtcatatttactggcaaccaatgagc gaagagtcgcgagcaactttaggaacattctatgttactaatacacttgaagttttacac cctgaaatacaggatgttgctggattagtcggcggcggcggggtgtcgatatactactcg cacatactgaagatgcttttcttctcctacgctcaagggaagagtttccttgcaccactt aacactgttgaagacagcgttaaaggcacagcgatgataacgctgtcgtcgtcatcggcg cagaaggagggtgggcgcggcaagcagggcggtgtgcagtcgctctgccagtgggccgag gtgcccggccaccccggcctcgtcaccgccgtcatgcaggcctccaacaaccccgtcgtg ctcatgctcacgccgaacaacatatatgtacaggagatcaaggtggtaccagcaaaagca aagataacagacatggtagctgtccggcactggtgtggaggtggcggcgaacagaaaagt actctcatactgttgtgcgaggacggcagtctacgtatgtacgcggctagtaacgaggac acaggttactggctatcgcctgccattcagccagtgcatgctcctaggcgtcgaccgagg cttctcactcatcacaataagggcaaagcgcaacaggttgtgacaaagtcaaattcgaat ggaacgccacaattccccattgacttctttgagcactgtgttgccatgagtgacattgaa tttggcggtaatgatctgcttcaagtttacaatacggcacaaattaaacaccgcctaaac aatactggtttatacgtagtatccacaaaaatgagtggtttcacaatggaagtcgtaaac tccgaccccaatatggtcatgtgtggtatacgagtgttgcttgggaaccaagatgttgct agaactccggcttatgtagagatacatggaaggtcaatacaaacaatcgttgttagaaat cgatggttcgatattccgctgacacgtgaggagtctttacagtctgataagaagctcgtt ataaactttggtccttctcaagaccccgatggtgtgacagtggttgattccgttaaagta tatggcaaaaataaagagcagtttggttggccagaagaaaacgaggatccttctgcttgc ccgtcatcgagtaaagtcgctcaggaatcggaaagcagcagcggttcatggaagccgagt tccctagagcggctagcgtgcgcggctctagaagccctcgagctgggcgcgggcgcgccc gccagcagcggcgcggcggcgggcgcggaggccggcgcggaggccgcgcgcaagctgctg tgcgcgccggcgtccgcgcacctgcacgcgcgcgcgcagtgcctgctgcgggccgtccac caggcgcagtaccaccagttcaaggatcaagcaatactaaaatacgtttcaacgtctctc cgcgagctgcgtgacacggcagatgcccgtaacatcgatcccgaggcgtacttccgtctc gtactactggcgcgaggcgtggccgtggcgcgcccgcaacatctcgtcaagtacagcggg cccacaccgcccaaacccaccgacggcgactggtcagcgctatggaaggcagattgtcaa gatgaacccgatcacgaaccgcatctatgtgcacttttgagtagcgtgttgtggaagttg acaggctgccgtagccagaccaccggcccgccgggcatcttgtcatatgggttaagacac gctgaacacacgctccacgcactagctgacaccatacatgcgttccaattgcacggagac tctgattgtattgatttcggaaatcaaatctacttatcgttactcctggctgaagaccag agtataagcttcggtgctaaggcggcacttatgcgtgtgttacgtccgcgtgtcaagaga cgcagagtgtacataccatcaccaccaaatacgccaggtgccgtttcatctgtaacaacg gctcaacccgccggttcaattactgaagcagtggtgtcagaggcggagttgagtgctaat cgcgatgatcaacaggagaaccagtatatggacgtagatgactcactcgaaccgatggtt ttacttgcgcctgatggaggcctcgaggcgctgctggacatcccgacggacgcggacgac gagacgatggtggagctggccatcgcgctgtcgctgcaggagcagggccggcgcgcgccg cccgcgcccgcgccgccgcccgcgcccgcgccgcacgcgcccgcctacagcgacgccacc gcctcgcccaacggatcggacgatgaaggtagcaccgctgcgacggacggtagtacattg cgcacgtcgccggccgaagccggcggatcggccgcttccgacagcggcggctcggcggcc gagagcatcggtggcgtctcgggccgaagcagcgcttacggagagatgtctgcgccctcc gggcagccgtgctccactgtcgtggaagttcctgctgcggttgcagcaggtccatcaagc tcgtctcaaccaatgccatcgacgtcccgcgcggcggaagtcgagaacgaggcgcgcaag ttgcacgcactgcgactgtccctgctgtccgctgctctggatgctttgcccacactcagg accttgcccggagtgcgcgctataccttttgtacaggttgttttaatgttggctggtgat ctcgactccagcgtcgaaggtgaccgagcggtactagagcgtttgctcgaagtactggtc ggtgaattggatattcaacccgaagagccgtcaagtggtgaagatcgcactgagaaacgt gagctgcaactagccatcatgaggctcgagttgctcgtctcggaactagacgagcaagtg gccgtgcactcgccgcctgtacacgaacgcaccaataggagggaacttcagctcgttatt atgaggttactcagtgtgctaatggctcgctggaagacgtgcggcgcgcacgcgggcggg gcgggcggcggtgcggcgcgcggggaggcgccgggcgccgcgtgcgccgcgcacgtgtcg cgcctggccgcggccgcgctggtgcgcgccggcgcgcccaagcactgctacaacgtgctc gccgcgctgctgccctactggaaggagaagactgccaattcaggcactacaacaactgtt cagcagttactaaaaccacaaccgccgcagccactaccagacatgcaaccattctttgtc aaagaatatgttaagagtcacgccttggacgtgtttgacaactacccacaattagtaatg gaaatggctttacggttgccgtgccaaatccacaagcactgtgacccgaaacatttcgat gcacgttggcgtacattactttgcgaatacatgatgaaccaacagacaccgctcaggaaa caagtccgcaagctactgctgctgttgtgcgggactcgcgagctctaccgccagctgcgc gacgtgcacgcgctcgacacgcacctaaacgccgcgcgcgcgctgctcgccaccgacccc gcctacgacaagctggtgcgcttgatggaccatttgaaggcgtgcgccgagatcgtgtcg gcgcgcacgggcaactggcagcacacgtgcgcgacggagcggcgcgagacgctgggctgg ctggtgggcgcggcgcggcgcctgcacccgcacgtggcgcccaccgtgctgcagctgctg caggcggcgctgtgcgcgcccgcgccgcccgcgccgcccacgccgcacacgccgcccggt acgaactggccagatcgtgaacgaagtaccgagagtgacgcgtttgtgtccgacggatct aagttccaggaacatagagtaccgcaactggtgcagcagatattaaaacaggtcaatcaa gatgaacttaaactatttgtgaaagcattccttttggagaccaactcaacagcagttcgc tggcaagcacatgctttacttcttgcgatttacaacaattgttcacaaactgaacaagcc tcccttgtgtctttgctgtggagcttgtggcctacactgcctcaatatggaagaaaagcg gtacaattcgtcgatctgcttggatatttcacgcttaaaactcctaacatcgatactgag tcgtacatcggcagcgcggtggagctgctccgcaaccagaaccaactgctgtcttcccac ggcaactccgctctgtacgcgtctctcggcgcctatgtggaactagacggctactacctc gagtccgagccgtgcctcgtctgcaacaacccggaggtgcccatggcatccatcaagctg cccaccattaagatcgactcgaagttcacgacaacgacgcagatcgtgaaactggtcaac agccacatgatcagtcgcatcagccttcgtatcggagacatcaagcggagcaagatggtg cgggttattaacttctactacaacaaccgtaccgttcaggccgtacaagagctcaagaat aaaccaagtatgtggcacaaagcgaaacgcgttcagctccagtcgggacagtcggaggtg cgcgtcgacttcccgcttccaattgttgcctgtaacctcatgatggagtacgctgacttt tatgaaaatcaacaagccacaggtgaatctctgcaatgtcctcgttgctctcaatctgta ccagccaatccgggagtgtgtggtaactgcggagaaaacgtcttccagtgccacaagtgc cgcgctataaactacgacgagaaagacccgttcttgtgccacgcgtgcggcttctgtaag tacgcgaagttcgactacactctaacggcgcggccgtgctgcgccgtggacaccatcgag aacgacgaggaacgcaagaagatggtgcagaccatcggcgcgctgctcgacaaggccgac cgcgtctaccgccagctcatcgccaacaagcccgtactggagtcgctggtgcacaagata agcgagcaccgcgtggaggggcgcgcggacgagaacagcaacggcgcgggcggcgccttc ggcggcgcgcagatcaaccgcgtcatacagatgctcgcacacaagtactgcgtcgagagc aagggccacttcgaggacctctccaagatcattcagaaggtgctcgcctgcaggaaagag ttagttgcctatgacagatcacaaagtgaacaacttgaaggggatacgttaccagtttat gctggcttattgcaaaattatgacggtgatgttactaaagagagcgggggctcgtgctac ggttgctcgctggcgtgcgccgagcagtgcctgacgctgctgcgcgcgctggcctcgcag cgcgagcaccgcgcgcgcctgtgccgcttcggcctcgtgcacgagctcgtgcaccacaac ctgcaccgtggcacgccgcagtgtcaagacgaagttcgctctctcatctgtctggtgacc cgtgataatctcccagcgacgaagcaattatgctatttgctgtcacagagaatcactctg tcgctaatgggtcatgccgcttcacaagaccataacaactccgtacgacctctggtgctt ttattgggcgcattggttaaagtccaagattcggtagaatgctgggaagtaagattgcgt tgcgttgtaaagctatgggtttggtgctgtcctcaactaacggaagtggtcggcatacca ccagcagccactgctatcttaaaatcagaagcgctgtctggtatccctggcataaatact tcgtcacctaactcgcaccagttcgcgctccagcaagtggcgctgccgtgcctgcgctac atgcaggagctgatggagccggccgcgcccgccgccgcgcccgcgcccgccgccgacgac caagctaaggacactaaggaatctactcagccaacagcacctccgcctatagtactacag gcgaatacaggcaacttagtggtagacttgtctgcttggctcgctggtagagtaccacat aagcagtggagaaaactagtagctaaaaacgagataccgcccgcagacactactctacct acccgcgatatacatctcgcccacaagtatcttggcaaatggaaagaaaagatgctgctg tcgcacggcatgcgcacgctgtcgctggacgcgggcggctggctgcggcccgtcatgttc gaccccagctcgcgcatcgcgcgcgacaccgcctgccagatggtcaagtcgctctgcgac tcctacgacaggactaaggcggttctcatactgttgacgagcttcttaccagaagtcgga gcagccggtgaagcaagcgagcaattcttgcaactgtaccaaagtctcgcatcagaagct ccatggaaacagttcttggcattgcgtggagtactacaacaaattgcagatctgatgacg aaagagattgatcagctgcatcgtcttgaagaaacaacactcacatctgacctggctcaa ggctacgcgctgaagcggctgacggagctgctggccatgttcctggaggaggcgggcgcg cggcgcgcctacaagacgcggctggtgggcgccgtgctgggcggctacctggcgctgcgc cgcctcgtggtgcagcgcacgcgcctcaccgacgacacgcaggagaagctgctcgagctg ctggaggagatgaccaccggcacggaagcggaaacggccgagtttatggcagtgtgcata gagacagttcagaagtacccgctccacgactatcgcacaccagtctttatattcgagcga ttatgttctatcatttaccccgaggagaacgacgtcggagaattcttcttgactttggag aaagatccgcaacaggaagatttcttgcagggacgaatgttaggcaatccgtattcgtcg ctcgaaccgggcatgggtccactaatgagagatgtaaagaacaaaatttgtacagattgt gaattggtagctcttctggaagatgacaacggcatggaactgcttgtttgtaacaagatc atgtcactggatttgcctgttaaagaagtttataaaaaggtgtggtgtacatcaggagaa ggtgtcgatgcaatgcgcgtcgtataccgcatgcgcggtttgctcggagacgccactgag gagttcgtggagactctcagccagaccaacgccgagactgtggacgacgaacaagtttat cgaatggcaaacgtgctcgctgactgcggcgggctggaggtgatgctgcagcggctggcg gccatcgggcgcgtggcgtgcgcgcgctcgctggcgggcacgctgctgcggctgctggcg ctgtgcgcgcgcgtgcggcgctgcgtgcgcgtgctgacgcggccggaggcgcgcgcgctg cccgtgctgctgcacgcgctcagcctggccgccgccgacgagcgcgacgggccgcgcgcg ccgctcgtctaccagctgctcgagatcatggaacgcatactttccgtcgcggctagcgaa agtctcgaatcgttcttgcagttctccctcacattcggcggaccggaacacgtacaagct ctactcaattgcactgaatgtccaggaatccgcaacaactcggtcgctctcggtcatctc acgcgtgtactcgcggcgctcgtttacggcaacgatctcaagatggctatgttagtggat cacttcaagcccgtactggatttcaaccgactggacaacgaacagtggagcgacgaagag ttccgcatggaactattctgcgtgctctgtgctaatatagaacgtaattctatcggggga acgttaaaggattacttgatatcgctaggcgttgtgcgagatgctttggagtatatcatg aaacatgccccatgcgtaaaaccaacgctcgtgtgcacggactcagacgagctaaaggag ttcatcagtcgacctgcgctcaaatacatcctgcgttttctcaccggcctcgctgcggac cacgagcctactcagatgctagtgtgcgagaacgtaataccgatcgtacatcgcttagag caagtgtcatccggtgaacacgtgggctctcttgcagagaatttactcgaagcgttgcgt tcacaaccgcaatgcgctgccaaagtgcagcaagtacgagatttcacgagacaggagaag aagcgcctggcgatggcggtgcgcgagcggcagctgggcgcgctgggcatgcgcagcaac gagcgcgggcaggtgacggcgcagtgcagcctcacgcagcaggtggccgacctggcggag gaggcgggcgccgtgtgctgcatctgccgcgagggctacaagtaccagcccaccaaggtg ctcggcatctacacgttcacgaagcgctgcccggtggaggagtacgaggcgcgcgcgcgc aagacgctcggctacaccacggtctcgcactacaacatcgtgcacgtggagtgccacatg gcggccgtgaggctcgcgcgagctagagatgaatgggaaagcgcggcattacaaaatgct tcaacaagatgtaacggcttgctacctctgtggggcccctacgtaccagaatcggcattt gcttcttgtcttgcaaggcatactacgtacttacaggagtgcacgggacaccgcgacatc ggtcacagctgcacggtacacgacctaaagctactgctgctgcggtttgcacgcggcctt agtttccacaacgacacgggcggcggcggcccgctctccaacatgcagctcgtgcctgct ctcatgcatatggcgctctacgtcatcaacacgacacgcgtagccgctcgcgaggtgtcc gcgctggaggcgagcctggcgtggccgccgccgcgcgtgctggagtcggcgcacgacgcc gagggcccgctctactacctcacgctcatgctgctgctctacccgcacgccaaatggcgc gcgctgcgcttggacatgatgaagcgcatgctgctggtggggcacgtgcgcgacgtggcg cgcggcgggccggcgctgcgcgcgctggcgcccgagcaccgcgcgccgcgcgcctggccc gagtacaagccctacctggtcttcgtggcgctcatccaccagctctacaccgtcatgttc aagaacgtgaacgcgacgacagtcgagcagtggccgatcaagctggccgagtacatccgg cacaacgacgaggcgaacgcgaaggcggccgagcgcatcgtgacgacgctgacggacgag ctgctcccgtgcgactcgctggccgagctgtgcgacgcggccggcttcctggacgacgcg cccgagcccgacgcgctgctgcagcggctgctggacgagcagccgtga

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