Mastomys coucha (southern multimammate mouse): 116070251
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Entry
116070251 CDS
T07224
Symbol
Plcg2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
mcoc
Mastomys coucha (southern multimammate mouse)
Pathway
mcoc00562
Inositol phosphate metabolism
mcoc01100
Metabolic pathways
mcoc01521
EGFR tyrosine kinase inhibitor resistance
mcoc04012
ErbB signaling pathway
mcoc04014
Ras signaling pathway
mcoc04020
Calcium signaling pathway
mcoc04062
Chemokine signaling pathway
mcoc04064
NF-kappa B signaling pathway
mcoc04066
HIF-1 signaling pathway
mcoc04070
Phosphatidylinositol signaling system
mcoc04072
Phospholipase D signaling pathway
mcoc04360
Axon guidance
mcoc04370
VEGF signaling pathway
mcoc04380
Osteoclast differentiation
mcoc04611
Platelet activation
mcoc04613
Neutrophil extracellular trap formation
mcoc04625
C-type lectin receptor signaling pathway
mcoc04650
Natural killer cell mediated cytotoxicity
mcoc04662
B cell receptor signaling pathway
mcoc04664
Fc epsilon RI signaling pathway
mcoc04666
Fc gamma R-mediated phagocytosis
mcoc04670
Leukocyte transendothelial migration
mcoc04722
Neurotrophin signaling pathway
mcoc04750
Inflammatory mediator regulation of TRP channels
mcoc04919
Thyroid hormone signaling pathway
mcoc04933
AGE-RAGE signaling pathway in diabetic complications
mcoc04935
Growth hormone synthesis, secretion and action
mcoc05167
Kaposi sarcoma-associated herpesvirus infection
mcoc05169
Epstein-Barr virus infection
mcoc05170
Human immunodeficiency virus 1 infection
mcoc05171
Coronavirus disease - COVID-19
mcoc05200
Pathways in cancer
mcoc05205
Proteoglycans in cancer
mcoc05206
MicroRNAs in cancer
mcoc05214
Glioma
mcoc05223
Non-small cell lung cancer
mcoc05225
Hepatocellular carcinoma
Module
mcoc_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
mcoc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
116070251 (Plcg2)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
116070251 (Plcg2)
04064 NF-kappa B signaling pathway
116070251 (Plcg2)
04066 HIF-1 signaling pathway
116070251 (Plcg2)
04070 Phosphatidylinositol signaling system
116070251 (Plcg2)
04072 Phospholipase D signaling pathway
116070251 (Plcg2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
116070251 (Plcg2)
04613 Neutrophil extracellular trap formation
116070251 (Plcg2)
04650 Natural killer cell mediated cytotoxicity
116070251 (Plcg2)
04662 B cell receptor signaling pathway
116070251 (Plcg2)
04664 Fc epsilon RI signaling pathway
116070251 (Plcg2)
04666 Fc gamma R-mediated phagocytosis
116070251 (Plcg2)
04670 Leukocyte transendothelial migration
116070251 (Plcg2)
04062 Chemokine signaling pathway
116070251 (Plcg2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
116070251 (Plcg2)
04919 Thyroid hormone signaling pathway
116070251 (Plcg2)
09156 Nervous system
04722 Neurotrophin signaling pathway
116070251 (Plcg2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
116070251 (Plcg2)
09158 Development and regeneration
04360 Axon guidance
116070251 (Plcg2)
04380 Osteoclast differentiation
116070251 (Plcg2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
116070251 (Plcg2)
05206 MicroRNAs in cancer
116070251 (Plcg2)
05205 Proteoglycans in cancer
116070251 (Plcg2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
116070251 (Plcg2)
05214 Glioma
116070251 (Plcg2)
05223 Non-small cell lung cancer
116070251 (Plcg2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
116070251 (Plcg2)
05171 Coronavirus disease - COVID-19
116070251 (Plcg2)
05167 Kaposi sarcoma-associated herpesvirus infection
116070251 (Plcg2)
05169 Epstein-Barr virus infection
116070251 (Plcg2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
116070251 (Plcg2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
116070251 (Plcg2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mcoc04131
]
116070251 (Plcg2)
Enzymes [BR:
mcoc01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
116070251 (Plcg2)
Membrane trafficking [BR:
mcoc04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
116070251 (Plcg2)
Endocytosis
Macropinocytosis
Phospholipase C
116070251 (Plcg2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF-hand_PLCG2
C2
SH3_1
SH3_9
PH
PH_12
EF-hand_PLCG1
SH2_1
SH3_2
PH_14
GDPD
EF-hand_like
Motif
Other DBs
NCBI-GeneID:
116070251
NCBI-ProteinID:
XP_031197390
LinkDB
All DBs
Position
Unknown
AA seq
1265 aa
AA seq
DB search
MTTMVNVDTLPEYEKSQIKRALELGTVMTVFSARKSTPERRTVQMIMETRQVAWSKTADK
IEGFLDIMEIKEIRPGKNSKDFERAKAVRHKADCCFTILYGTQFVLNTLSLATDSKEDAV
QWLSGLKILHQEAMSASTPTMIESWLRKQIYSVDQTRRNSISLRELKAILPLVNFKVSGI
KFLKDKLVEIGAQKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASA
VYLQDFQRFLLHEQQELWAQDLNKVREQMTKFIDDTMRETAEPFLFVDEFLTYLFSRENS
IWDEKYDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRAGCRCIELDC
WDGPDGKPIIYHGWTRTTKIKFDDVVQAIRDHAFVTSSFPVILSIEEHCSVEQQRHMAKV
FKEVLGDLLLTKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNVDDKKDEHKTQGE
LYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTVEEELVQDTPPTELHFGEKWFHKKVERR
TSAEKLLQEYCAETGAKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMENGVMKYY
LTDNLTFNSIYALIQHYREAHLRCAEFELRLTDPVPNPNPHESKPWYYDRLSRGEAEDML
MRIPRDGAFLIRKREGTDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYY
EKHALYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDY
KAKRSDELTFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISAGDAEDMEKQII
EDNPLGSLCRGILDLNTYNVVKAPQGKNQKAFVFILEPKKQGDPPVEFATDRVEELFEWF
QSIREITWKMDTKENNMKYWERNQSIAIELSDLVVYCKPTSKTKDHLENPDFREIRSFVE
TKADSIVRQKPVDLLRYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTPDKY
MQMNHALFSLNGRTGYVLQPESMRSEKYDPMPPESQRKILMTLTVKVLGARHLPKLGRSI
ACPFVEVEICGAEYDSNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLRFVVYEED
MFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSC
RQLRRRQEEINNQLYLYETHQNLRGANRDALVKEFNVNENQLQLYQEKCNRRLREKRVSN
SRFYS
NT seq
3798 nt
NT seq
+upstream
nt +downstream
nt
atgaccaccatggtcaatgtggacacccttccagaatatgagaagagtcagatcaagaga
gccctggagctagggacggtgatgaccgtgttcagcgcccgcaaatccaccccagagcgg
aggacagtacagatgatcatggagacccgacaggtggcatggagcaagaccgcagacaag
attgaaggtttcttggacatcatggaaataaaggagatccgtccggggaagaactccaag
gactttgagcgagccaaggctgtccggcacaaggcagactgttgcttcactatcctctac
ggcacccagttcgtcctcaacacactcagtttggcaactgattcgaaggaggatgcggtg
cagtggctctctggcttgaagatcctacaccaggaagcgatgagtgcatccactcctaca
atgattgagagttggctgcgaaaacagatttattcggtagatcaaacccgaagaaacagc
atcagtctccgggagctgaaggccatcctgcccctggtcaacttcaaagtgagcggcatc
aagtttctcaaggacaagctggtggaaatcggtgcgcagaaagatgagctcagttttgaa
cagttccatctcttctataaaaaactcatgtttgagcagcaaaagtcgatacttgacgaa
ttcaaaaaagactcctccgtgttcatcctagggaacacagaccggcctgatgcctcagct
gtctacctgcaggacttccagaggtttcttttacatgaacagcaggagctttgggctcag
gatttgaacaaggtccgggagcagatgaccaagtttatcgatgacacaatgagggagact
gcagagcccttcttgtttgtggacgagtttctcacgtacctgttctcacgggagaacagc
atctgggacgagaagtacgatgcagtggacatgcaagacatgaacaatcccttgtctcat
tactggatctcttcttcccacaacacgtacctcaccggggaccagctgcgtagtgagtcc
tccacggaagcatatatccgctgtctgcgtgctggttgccgctgtattgagttggactgc
tgggatgggcctgacgggaaacccataatctatcacggctggacacggaccaccaagatc
aagtttgatgatgttgttcaggccatccgggaccatgcctttgttacctccagcttccct
gtgatcttgtctattgaggaacactgcagtgtggagcagcagcgtcacatggccaaagtg
ttcaaggaagtgttaggagacctgctgttgaccaagcccacggaggccagtgctgaccag
ttgccctcgcccagtcagcttcgtgagaagatcattatcaagcataagaagctgggcccc
cggggtgatgtcgatgtcaatgtggatgacaagaaagatgagcacaagacccagggagag
ctgtacatgtgggactccattgaccagaaatggacgcgccactactgtgccattgctgac
gccaagctgtccttcagtgatgacattgaacagactgtggaggaggagctggtccaggac
actccccccacggagctgcattttggggagaaatggttccataagaaggttgagaggagg
accagtgcggagaagctactgcaagagtactgtgcggagaccggggccaaggacggcacc
ttcctggtgcgggagagcgagaccttccccaacgactacacactctccttctggcggtct
ggccgggtgcagcactgccggatccggtctaccatggagaatggggtcatgaagtactac
ctaactgacaacctcaccttcaacagcatctacgccctcatccagcactaccgtgaggca
catctgcgctgtgcggagttcgagctgcggcttacagacccggtgcccaatcccaaccca
catgagtccaagccgtggtactatgacagactgagcaggggggaagcagaggacatgctg
atgcggattccccgggatggagccttcctcatccggaagcgggaggggaccgattcttac
gccatcaccttcagggccaggggcaaggtgaaacactgccgcatcaaccgggatggacgc
cactttgtgctggggacctctgcctactttgagagcctggtggagcttgtcagctactac
gagaagcatgcactctatcgcaagatgaggctccgctaccccgtgaccccagagctcctg
gagcgatataatatggaaagagacatcaattccctctatgacgtcagcaggatgtatgtg
gacccgagtgagatcaacccttccatgcctcagaggactgtgaaagcgctctatgactac
aaagccaagcgcagcgatgagctgaccttttgccgcggtgccctcatccacaatgtctcc
aaggagcccgggggatggtggaaaggggactacgggacccggatccagcagtacttcccg
tccaactatgttgaggatatctctgcaggagatgctgaggacatggaaaagcagattatt
gaagacaatccccttgggtctctctgcagaggcatattggatcttaatacctacaatgtt
gtgaaagccccccaggggaaaaaccagaaagcctttgtcttcatcctggagcctaagaaa
cagggggatcctcctgtggagttcgcaacggaccgtgtggaggaactgtttgaatggttt
cagagcatccgagagatcacttggaaaatggacaccaaggagaacaacatgaaatactgg
gagaggaaccagtccattgctattgagctctctgacttggttgtgtactgcaagccaact
agcaaaaccaaggaccatttggaaaatcctgacttccgagaaatccgctctttcgtggag
acaaaggcagacagcatcgtcaggcaaaagcctgtggatctattgcggtacaatcagaag
ggcctgacccgcgtctaccccaagggacagagagttgactcttcgaactacgaccccttc
cgtctgtggctatgtggctcccagatggtggcgctcaatttccagactccagacaagtac
atgcagatgaaccatgcgctgttttcgctcaatgggaggacaggctacgtcctgcagcct
gagagcatgcgctccgagaagtatgacccaatgcccccagagtcccagaggaagatcctg
atgacactcactgtcaaggttcttggtgcacgccacctccccaaactagggcggagtatc
gcctgtccctttgtggaggtggaaatctgcggggctgagtacgacagcaacaaattcaag
acgacagttgtgaacgacaatggcctcagccctgtctgggctccaactcaggagaaggtg
acatttgaaatttatgatccaaacctcgcgttcctacgctttgtggtctatgaagaagac
atgttcagtgaccccaacttcctggctcatgccacataccccattaaaggcatcaaatcg
gggtttagatcagtccctctgaagaacgggtacagtgaagacatcgagctggcatccctc
ctggttttctgtgagatgcggccagtcctggagagtgaagaagaactctattcctcctgt
cgccaactgcggaggcggcaggaagagatcaacaaccagctctacctgtatgagacacac
cagaaccttcgaggagccaaccgtgatgcccttgtgaaggagttcaacgttaacgagaat
cagctgcagctgtaccaggagaagtgcaaccggaggctgagagagaagagagtgagcaac
agcaggttctactcctag
DBGET
integrated database retrieval system
