Mastomys coucha (southern multimammate mouse): 116073280
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Entry
116073280 CDS
T07224
Symbol
Bace1
Name
(RefSeq) beta-secretase 1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
mcoc
Mastomys coucha (southern multimammate mouse)
Pathway
mcoc05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
mcoc00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
116073280 (Bace1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
mcoc01002
]
116073280 (Bace1)
Enzymes [BR:
mcoc01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
116073280 (Bace1)
Peptidases and inhibitors [BR:
mcoc01002
]
Aspartic peptidases
Family A1: pepsin family
116073280 (Bace1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
PE-PGRS_C
Motif
Other DBs
NCBI-GeneID:
116073280
NCBI-ProteinID:
XP_031200933
LinkDB
All DBs
Position
Unknown
AA seq
501 aa
AA seq
DB search
MAPALRWLLLWVGSGMLPAQGTHLGIRLPLRSGLAGPPLGLRLPRETDEEPEEPGRRGSF
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
GLAYAEIARPDDSLEPFFDSLVKQTRIPNIFSLQLCGTGFPLNQTEALASVGGSMIIGGI
DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
HVHDEFRTAAVEGPFVTAGMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
RCLRCLRHQHDDFADDISLLK
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atggccccggcgctgcgctggctcctgctatgggtaggctcgggaatgctgcctgcccag
ggaacccatctcggcatccgtctgccccttcgcagcggcctggcagggccacccctgggc
ctgaggctgccccgggagacggacgaggaacctgaggagcctggccggagaggcagcttt
gtggagatggtggacaacctgaggggaaaatccggccagggctactatgtggagatgacc
gtgggtagccccccacagacgctcaacatcctggtggacacgggcagtagtaactttgca
gtgggggctgccccacaccctttcctgcatcgctattaccagagacagctgtccagcaca
taccgagacctccgaaagggtgtgtatgtgccctacacccagggcaagtgggagggggaa
ctgggcaccgacctggtgagcatccctcatggtcccaacgtcactgtgcgtgccaacatt
gctgccatcactgaatcggacaagttcttcatcaatggttccaactgggagggcatccta
gggctggcctatgctgagattgccaggcccgatgactccttggagcccttttttgactca
ctggtgaagcagacccgcattcccaacatcttttccctgcagctctgcggcactggcttc
cccctcaaccagaccgaggcgctggcctcggtgggagggagcatgatcattggtggtatt
gaccactcgctatacacgggcagtctctggtacacacccatccggcgggagtggtattat
gaagtgatcattgtacgtgtggaaatcaatggtcaggatctgaagatggactgcaaggag
tacaactatgacaagagcatcgtagacagtggcaccaccaaccttcgcttgcccaagaaa
gtatttgaagctgctgtcaagtccatcaaggcagcctcctcgacggagaagttcccggat
ggcttttggctaggggagcagctggtgtgctggcaagcaggcacgaccccttggaacatt
ttcccagtcatttcactttacctcatgggtgaagtcaccaatcagtccttccgcatcacc
atccttcctcagcaatacctacggccagtggaagatgtggctacgtcccaagacgactgt
tacaagtttgccatttcacagtcatccacgggcactgttatgggagccgtcatcatggaa
ggcttctatgttgtctttgatcgagcccgaaagcgaattggctttgctgtcagcgcttgc
catgtgcacgatgagttcaggacagcggcagtggaaggtccgtttgttactgcaggcatg
gaagactgtggctacaacattccacagacagatgagtcgacacttatgaccatagcctat
gtcatggctgccatctgtgccctcttcatgttgccactctgcctcatggtatgtcagtgg
cgctgcctacgctgcctgcgccatcagcatgatgactttgctgatgacatctccctgctg
aaataa
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